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Cited by 291

The DOI matches its Crossref record; 108 of the 108 references it cites were found in a registry or an index.

Roles of Oxidative Stress and Inflammation in Vascular Endothelial Dysfunction-Related Disease

Open access
Higashi, Yukihito·2022·Antioxidants

Abstract

Oxidative stress and chronic inflammation play an important role in the pathogenesis of atherosclerosis. Atherosclerosis develops as the first step of vascular endothelial dysfunction induced by complex molecular mechanisms. Vascular endothelial dysfunction leads to oxidative stress and inflammation of vessel walls, which in turn enhances vascular endothelial dysfunction. Vascular endothelial dysfunction and vascular wall oxidative stress and chronic inflammation make a vicious cycle that leads to the development of atherosclerosis. Simultaneously capturing and accurately evaluating the association of vascular endothelial function with oxidative stress and inflammation would be useful for elucidating the pathophysiology of atherosclerosis, determining treatment efficacy, and predicting future cardiovascular complications. Intervention in both areas is expected to inhibit the progression of atherosclerosis and prevent cardiovascular complications.

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Crossref · 10.3390/antiox11101958

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Metadata

Authors
Higashi, Y.
Venue
Antioxidants
Publisher
MDPI AG
Published
2022-09-30
Volume
11
Issue
10
Pages
1958
ISSN
2076-3921 (ISSN-L)
OpenAlex
W4303579210
Cited by
291
References
108
FWCI
26.57
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Roles of Oxidative Stress and Inflammation in Vascular Endothelial Dysfunction-Related Disease. https://app.cochat.ai/papers/10.3390/antiox11101958
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Higashi, Y. (2022). Roles of Oxidative Stress and Inflammation in Vascular Endothelial Dysfunction-Related Disease. Antioxidants. https://doi.org/10.3390/antiox11101958

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.