The DOI matches its Crossref record; 133 of the 133 references it cites were found in a registry or an index.
Neuroprotective Effects of Quercetin in Alzheimer’s Disease
Open accessAbstract
Quercetin is a flavonoid with notable pharmacological effects and promising therapeutic potential. It is widely distributed among plants and found commonly in daily diets predominantly in fruits and vegetables. Neuroprotection by quercetin has been reported in several in vitro studies. It has been shown to protect neurons from oxidative damage while reducing lipid peroxidation. In addition to its antioxidant properties, it inhibits the fibril formation of amyloid-β proteins, counteracting cell lyses and inflammatory cascade pathways. In this review, we provide a synopsis of the recent literature exploring the relationship between quercetin and cognitive performance in Alzheimer’s disease and its potential as a lead compound in clinical applications.
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Neuroinflammation in Alzheimer's disease
Heneka, M. T., Carson, M. J., Khoury, J. E., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., et al. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)70016-5 · Cited by 6,226
The neuropathological diagnosis of Alzheimer's disease
DeTure, M. A., & Dickson, D. W. (2019) · Molecular Neurodegeneration · doi:10.1186/s13024-019-0333-5 · Cited by 3,329
Nelson, P. T., Alafuzoff, I., Bigio, E. H., Bouras, C., Braak, H., Cairns, N. J., Castellani, R. J., Crain, B. J., Davies, P., Tredici, K. D., et al. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e31825018f7 · Cited by 2,050
Quercetin, Inflammation and Immunity
Li, Y., Yao, J., Han, C., Yang, J., Chaudhry, M., Wang, S., Liu, H., & Yin, Y. (2016) · Nutrients · doi:10.3390/nu8030167 · Cited by 1,999
The Cellular Phase of Alzheimer’s Disease
De Strooper, B., & Karran, E. (2016) · Cell · doi:10.1016/j.cell.2015.12.056 · Cited by 1,990
Overviews of biological importance of quercetin: A bioactive flavonoid
Parasuraman, S., Anand David, A., & Arulmoli, R. (2016) · Pharmacognosy Reviews · doi:10.4103/0973-7847.194044 · Cited by 1,610
The Pharmacological Potential of Rutin
Ganeshpurkar, A., & Saluja, A. K. (2017) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2016.04.025 · Cited by 1,253
Epidemiology of Alzheimer Disease
Mayeux, R., & Stern, Y. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006239 · Cited by 1,064
Anti-inflammatory Plant Flavonoids and Cellular Action Mechanisms
Kim, H. P., Son, K. H., Chang, H. W., & Kang, S. S. (2004) · Journal of Pharmacological Sciences · doi:10.1254/jphs.crj04003x · Cited by 1,014
Cited by
An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases
Teleanu, D. M., Niculescu, A.-G., Lungu, I. I., Radu, C. I., Vladâcenco, O., Roza, E., Costăchescu, B., Grumezescu, A. M., & Teleanu, R. I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23115938 · Cited by 1,085
Astrocytic and microglial cells as the modulators of neuroinflammation in Alzheimer’s disease
Singh, D. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02565-0 · Cited by 569
Jurcău, M. C., Andronie-Cioara, F. L., Jurcău, A., Marcu, F., Ţiț, D. M., Pașcalău, N., & Nistor-Cseppentö, D. C. (2022) · Antioxidants · doi:10.3390/antiox11112167 · Cited by 226
Rahman, M. H., Bajgai, J., Fadriquela, A., Sharma, S., Trinh, T. T., Akter, R., Jeong, Y. J., Goh, S. H., Kim, C.-S., & Lee, K.-J. (2021) · Molecules · doi:10.3390/molecules26175327 · Cited by 182
Neuropharmacological Effects of Quercetin: A Literature-Based Review
Islam, M. S., Quispe, C., Hossain, R., Islam, M. T., Al-Harrasi, A., Al-Rawahi, A., Martorell, M., Mamurova, A., Seilkhan, A., Altybaeva, N., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.665031 · Cited by 165
Metadata
- Authors
- Khan, H., Ullah, H., Aschner, M., Cheang, W. S., & Akkol, E. K.
- Venue
- Biomolecules
- Publisher
- MDPI AG
- Published
- 2019-12-30
- Volume
- 10
- Issue
- 1
- Pages
- 59
- ISSN
- 2218-273X (ISSN-L)
- OpenAlex
- W2997032704
- Cited by
- 537
- References
- 133
- FWCI
- 24.57
- Type
- journal article
- Language
- en
- Open access
- gold
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- Khan, H., Ullah, H., Aschner, M., Cheang, W. S., & Akkol, E. K. (2019). Neuroprotective Effects of Quercetin in Alzheimer’s Disease. Biomolecules. https://doi.org/10.3390/biom10010059
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
