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Combination of Cell-Penetrating Peptides with Nanoparticles for Therapeutic Application: A Review
Open accessAbstract
Cell-penetrating peptides (CPPs), also known as protein translocation domains, membrane translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid residues capable of penetrating biological barriers and cellular membranes. Furthermore, CPP have become an alternative strategy to overcome some of the current drug limitations and combat resistant strains since CPPs are capable of delivering different therapeutic molecules against a wide range of diseases. In this review, we address the recent conjugation of CPPs with nanoparticles, which constitutes a new class of delivery vectors with high pharmaceutical potential in a variety of diseases.
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Cited by
Strategies for delivering therapeutics across the blood–brain barrier
Terstappen, G. C., Meyer, A. H., Bell, R. D., & Zhang, W. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-021-00139-y · Cited by 1,138
Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine
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Gene Delivery Technologies with Applications in Microalgal Genetic Engineering
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Alishah Aratboni, H., Rafiei, N., Mehdizadeh Allaf, M., Abedini, S., Naseema Rasheed, R., Seif, A., Barati, B., Wang, S., & Morones-Ramírez, J. R. (2023) · Algal Research · doi:10.1016/j.algal.2023.103019 · Cited by 43
Metadata
- Authors
- Silva, S., Almeida, A., & Vale, N.
- Venue
- Biomolecules
- Publisher
- MDPI AG
- Published
- 2019-01-10
- Volume
- 9
- Issue
- 1
- Pages
- 22
- ISSN
- 2218-273X (ISSN-L)
- OpenAlex
- W2911207445
- Cited by
- 223
- References
- 6
- FWCI
- 10.24
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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