The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Point-of-Care Diagnostics in Low Resource Settings: Present Status and Future Role of Microfluidics
Open accessAbstract
The inability to diagnose numerous diseases rapidly is a significant cause of the disparity of deaths resulting from both communicable and non-communicable diseases in the developing world in comparison to the developed world. Existing diagnostic instrumentation usually requires sophisticated infrastructure, stable electrical power, expensive reagents, long assay times, and highly trained personnel which is not often available in limited resource settings. This review will critically survey and analyse the current lateral flow-based point-of-care (POC) technologies, which have made a major impact on diagnostic testing in developing countries over the last 50 years. The future of POC technologies including the applications of microfluidics, which allows miniaturisation and integration of complex functions that facilitate their usage in limited resource settings, is discussed The advantages offered by such systems, including low cost, ruggedness and the capacity to generate accurate and reliable results rapidly, are well suited to the clinical and social settings of the developing world.
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Citations
Cites
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Global status report on noncommunicable diseases
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Designs, formats and applications of lateral flow assay: A literature review
Sajid, M., Kawde, A.-N., & Daud, M. (2015) · Journal of Saudi Chemical Society · doi:10.1016/j.jscs.2014.09.001 · Cited by 765
Cited by
Land, K. J., Boeras, D. I., Chen, X.-S., Ramsay, A. R., & Peeling, R. W. (2018) · Nature Microbiology · doi:10.1038/s41564-018-0295-3 · Cited by 1,065
Metadata
- Authors
- Sharma, S., Zapatero-Rodríguez, J., Estrela, P., & O'Kennedy, R.
- Venue
- Biosensors
- Publisher
- MDPI AG
- Published
- 2015-08-13
- Volume
- 5
- Issue
- 3
- Pages
- 577-601
- ISSN
- 2079-6374 (ISSN-L)
- OpenAlex
- W1898049656
- Cited by
- 349
- References
- 33
- FWCI
- 17.77
- Type
- journal article
- Language
- en
- Open access
- gold
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