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Cited by 349

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Point-of-Care Diagnostics in Low Resource Settings: Present Status and Future Role of Microfluidics

Open access
Sharma, Shikha, Zapatero-Rodríguez, Julia, Estrela, Pedro, O'Kennedy, Richard·2015·Biosensors
DOI 10.3390/bios5030577
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Abstract

The inability to diagnose numerous diseases rapidly is a significant cause of the disparity of deaths resulting from both communicable and non-communicable diseases in the developing world in comparison to the developed world. Existing diagnostic instrumentation usually requires sophisticated infrastructure, stable electrical power, expensive reagents, long assay times, and highly trained personnel which is not often available in limited resource settings. This review will critically survey and analyse the current lateral flow-based point-of-care (POC) technologies, which have made a major impact on diagnostic testing in developing countries over the last 50 years. The future of POC technologies including the applications of microfluidics, which allows miniaturisation and integration of complex functions that facilitate their usage in limited resource settings, is discussed The advantages offered by such systems, including low cost, ruggedness and the capacity to generate accurate and reliable results rapidly, are well suited to the clinical and social settings of the developing world.

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Metadata

Authors
Sharma, S., Zapatero-Rodríguez, J., Estrela, P., & O'Kennedy, R.
Venue
Biosensors
Publisher
MDPI AG
Published
2015-08-13
Volume
5
Issue
3
Pages
577-601
ISSN
2079-6374 (ISSN-L)
DOI
10.3390/bios5030577
OpenAlex
W1898049656
Cited by
349
References
33
FWCI
17.77
Type
journal article
Language
en
Open access
gold

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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