A Novel Photoplethysmography Sensor for Vital Signs Monitoring from the Human Trachea
Open accessAbstract
Current pulse oximeter sensors can be challenged in working accurately and continuously in situations of reduced periphery perfusion, especially among anaesthetised patients. A novel tracheal photoplethysmography (PPG) sensor has been developed in an effort to address the limitations of current pulse oximeters. The sensor has been designed to estimate oxygen saturation (SpO2) and pulse rate, and has been manufactured on a flexible printed circuit board (PCB) that can adhere to a standard endotracheal (ET) tube. A pilot clinical trial was carried out as a feasibility study on 10 anaesthetised patients. Good quality PPGs from the trachea were acquired at red and infrared wavelengths in all patients. The mean SpO2 reading for the ET tube was 97.1% (SD 1.0%) vs. the clinical monitor at 98.7% (SD 0.7%). The mean pulse rate for the ET sensor was 65.4 bpm (SD 10.0 bpm) vs. the clinical monitor at 64.7 bpm (SD 9.9 bpm). This study supports the hypothesis that the human trachea could be a suitable monitoring site of SpO2 and other physiological parameters, at times where the periphery circulation might be compromised.
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Peripheral vasoconstriction can result in low-quality PPG signals.
“Peripheral vasoconstriction can also result in low-quality signals [52].”
From Wearable Photoplethysmography for Cardiovascular Monitoring (2022) · cites this paper as [52]
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Cites
STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT
Martin Bland, J., & Altman, D. (1986) · The Lancet · doi:10.1016/s0140-6736(86)90837-8 · Cited by 47,965 · see citing works
(1997) · Institute of Physics eBooks · doi:10.1887/0750304677 · Cited by 455 · see citing works
Masimo Signal Extraction Pulse Oximetry
Goldman, J. M., Petterson, M. T., Kopotic, R. J., & Barker, S. J. (2000) · Journal of Clinical Monitoring and Computing · doi:10.1023/a:1011493521730 · Cited by 283 · see citing works
Pulse Oximetry: Uses and Limitations
DeMeulenaere, S. (2007) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2007.02.021 · Cited by 109 · see citing works
Effect of skin pigmentation on pulse oximetry accuracy in the emergency department
Adler, J. N., Hughes, L. A., Vtvilecchia, R., & Jr., C. A. C. (1998) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.1998.tb02772.x · Cited by 102 · see citing works
Chatterjee, S., & Kyriacou, P. A. (2019) · Sensors · doi:10.3390/s19040789 · Cited by 86 · see citing works
Self-citationKyriacou, P. A., Powell, S., Langford, R. M., & Jones, D. P. (2002) · Physiological Measurement · doi:10.1088/0967-3334/23/3/305 · Cited by 61 · see citing works
Self-citationDesign and Development of a Modular, Multichannel Photoplethysmography System
Budidha, K., Rybynok, V., & Kyriacou, P. A. (2018) · IEEE Transactions on Instrumentation and Measurement · doi:10.1109/tim.2018.2810643 · Cited by 49 · see citing works
Self-citationEvaluation of oesophageal pulse oximetry in patients undergoing cardiothoracic surgery*
Kyriacou, P. A., Powell, S. L., Jones, D. P., & Langford, R. M. (2003) · Anaesthesia · doi:10.1046/j.1365-2044.2003.03091.x · Cited by 36 · see citing works
Self-citationDesign and development of a novel multi-channel photoplethysmographic research system
Rybynok, V. O., May, J. M., Budidha, K., & Kyriacou, P. A. (2013) · doi:10.1109/pht.2013.6461336 · Cited by 32 · see citing works
Self-citationInvestigation of the human oesophagus as a new monitoring site for blood oxygen saturation
Kyriacou, P. A., Moye, A. R., Choi, D. M., Langford, R. M., & Jones, D. P. (2001) · Physiological Measurement · doi:10.1088/0967-3334/22/1/325 · Cited by 28 · see citing works
Self-citationPälve, H., & Vuori, A. (1991) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1016/1053-0770(91)90154-l · Cited by 19 · see citing works
Measurement of splanchnic photoplethysmographic signals using a new reflectance fiber optic sensor
Hickey, M., Samuels, N., Randive, N., Langford, R. M., & Kyriacou, P. A. (2010) · Journal of Biomedical Optics · doi:10.1117/1.3374355 · Cited by 15 · see citing works
Self-citationDevelopment of a New Splanchnic Perfusion Sensor
Hickey, F. M., & Kyriacou, P. A. (2007) · Conference proceedings · doi:10.1109/iembs.2007.4352948 · Cited by 11 · see citing works
Self-citationMay, J. M., Kyriacou, P. A., & Petros, A. (2011) · doi:10.1109/iembs.2011.6089886 · Cited by 8 · see citing works
Self-citationInvestigation of photoplethysmographs from the anterior fontanelle of neonates
May, J. M., Kyriacou, P. A., Honsel, M., & Petros, A. (2014) · Physiological Measurement · doi:10.1088/0967-3334/35/10/1961 · Cited by 6 · see citing works
Self-citationShivering and pulse oximeter function
Langton, J. A. (1992) · Anaesthesia · doi:10.1111/j.1365-2044.1992.tb02399.x · Cited by 5 · see citing works
Dermatologic complication following axillary cannulation for aortic dissection repair
Nguyen, R. D., Hierlmeier, B. J., & Kurnutala, L. N. (2019) · Clinical Case Reports · doi:10.1002/ccr3.1969 · Cited by 2 · see citing works
May, J., Phillips, J. P., Snidvongs, S., & Kyriacou, P. A. (2019) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2019.8856662 · Cited by 1 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Wearable Photoplethysmography for Cardiovascular Monitoring
Charlton, P. H., Kyriacou, P. A., Mant, J., Marozas, V., Chowienczyk, P., & Alastruey, J. (2022) · Proceedings of the IEEE · doi:10.1109/jproc.2022.3149785 · Cited by 250 · see citing works
Self-citationA Self-Powered Portable Flexible Sensor of Monitoring Speed Skating Techniques
Lu, Z., Zhu, Y., Jia, C., Zhao, T., Bian, M., Jia, C., Zhang, Y., & Mao, Y. (2021) · Biosensors · doi:10.3390/bios11040108 · Cited by 34 · see citing works
Application of Modern Multi-Sensor Holter in Diagnosis and Treatment
Vavrinský, E., Subjak, J., Donoval, M., Wagner, A., Zavodnik, T., & Svobodová, H. (2020) · Sensors · doi:10.3390/s20092663 · Cited by 32 · see citing works
The Concept of Advanced Multi-Sensor Monitoring of Human Stress
Vavrinský, E., Stopjaková, V., Kopáni, M., & Kosnacova, H. (2021) · Sensors · doi:10.3390/s21103499 · Cited by 32 · see citing works
Oxygen Saturation Behavior by Pulse Oximetry in Female Athletes: Breaking Myths
Martín-Escudero, P., Cabanas, A. M., Fuentes, M. E., & Galindo-Canales, M. (2021) · Biosensors · doi:10.3390/bios11100391 · Cited by 25 · see citing works
Photoplethysmography in oxygenation and blood volume measurements
Abay, T. Y., & Kyriacou, P. A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823374-0.00003-7 · Cited by 16 · see citing works
Self-citationTrace Polymer-Bonded carbon nanotube networks for precise strain sensing in healthcare
Wang, J., Chang, X., Gao, Y., Wang, Y., Wu, H., Dong, S., & Wang, H. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.161142 · Cited by 7 · see citing works
Intra-tracheal multiplexed sensing of contact pressure and perfusion
Correia, R. G., Gadsby, B., Korposh, S., Norris, A. M., Hayes‐Gill, B., Sinha, R., Hardman, J. G., Gardner, D. S., Talbot, S., Harvey, D., et al. (2021) · Biomedical Optics Express · doi:10.1364/boe.442165 · Cited by 7 · see citing works
Flexible photoplethysmographic sensing devices for intelligent medical treatment
Wu, W., Wang, L., & Shen, G. (2022) · Journal of Materials Chemistry C · doi:10.1039/d2tc03318f · Cited by 7 · see citing works
Fabricating Novel PDMS Vessels for Phantoms in Photoplethysmography Investigations
Nomoni, M., May, J. M., & Kyriacou, P. A. (2020) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc44109.2020.9176476 · Cited by 6 · see citing works
Self-citationGao, Y., Fang, Y., Zhang, C., Zhou, D., & Ju, Z. (2025) · IEEE Sensors Journal · doi:10.1109/jsen.2025.3605063 · Cited by 4 · see citing works
Kanter, K. N., Wang, A., Gordon, D., Singer, A., Brenner, J. S., Gurubhagavatula, I., Lingamoorthy, A., Oni, O. O., & Baston, C. M. (2026) · Sensors · doi:10.3390/s26041276
Non-Contact Vital Signs Estimation Ml and Dl Techniques: A Comprehensive Survey
Shobana, T. S. (2026) · Journal of Intelligent Decision Making and Information Science · doi:10.59543/jidmis.v3.1396
- Authors
- May, J. M., Phillips, J. P., Fitchat, T., Ramaswamy, S., Snidvongs, S., & Kyriacou, P. A.
- Affiliations
- City, University of London (GB)
- Barts Health NHS Trust (GB)
- Corresponding author
- May, James M.
- Venue
- Biosensors
- Publisher
- MDPI AG
- Published
- 2019-10-02
- Volume
- 9
- Issue
- 4
- Pages
- 119
- ISSN
- 2079-6374 (ISSN-L)
- PMC
- PMC6956046
- OpenAlex
- W2978363524
- Cited by
- 12
- References
- 19
- Citations by year
- 2025: 2 · 2022: 3 · 2021: 5 · 2020: 2
- FWCI
- 0.88
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Biosensors (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- City Research Online (City University London) (acceptedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Barts Charity (832/2130)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Physical Sciences › Chemical Engineering › Bioengineering › Analytical Chemistry and Sensors
- Keywords
- pulse oximetry, endotracheal tube, pulse rate monitoring, anaesthetised patients, vital signs monitoring
- MeSH terms
- Adult, Female, Humans, Male, Middle Aged, Monitoring, Physiologic, Oximetry, Signal Processing, Computer-Assisted, Trachea, Biosensing Techniques, Photoplethysmography, Vital Signs
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