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Cited by 369

The DOI matches its Crossref record; 263 of the 263 references it cites were found in a registry or an index.

Helicobacter pylori Virulence Factors—Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment

Open access
Baj, Jacek, Forma, Alicja, Sitarz, Monika, Portincasa, Piero, Garruti, Gabriella, Krasowska, Danuta, Maciejewski, Ryszard·2020·Cells

Abstract

Gastric cancer constitutes one of the most prevalent malignancies in both sexes; it is currently the fourth major cause of cancer-related deaths worldwide. The pathogenesis of gastric cancer is associated with the interaction between genetic and environmental factors, among which infection by Helicobacter pylori (H. pylori) is of major importance. The invasion, survival, colonization, and stimulation of further inflammation within the gastric mucosa are possible due to several evasive mechanisms induced by the virulence factors that are expressed by the bacterium. The knowledge concerning the mechanisms of H. pylori pathogenicity is crucial to ameliorate eradication strategies preventing the possible induction of carcinogenesis. This review highlights the current state of knowledge and the most recent findings regarding H. pylori virulence factors and their relationship with gastric premalignant lesions and further carcinogenesis.

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Registry

Crossref · 10.3390/cells10010027

Cites

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Citations

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Metadata

Authors
Baj, J., Forma, A., Sitarz, M., Portincasa, P., Garruti, G., Krasowska, D., & Maciejewski, R.
Venue
Cells
Publisher
MDPI AG
Published
2020-12-25
Volume
10
Issue
1
Pages
27
ISSN
2073-4409 (ISSN-L)
OpenAlex
W3115502776
Cited by
369
References
263
FWCI
30.60
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Helicobacter pylori Virulence Factors—Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment. https://app.cochat.ai/papers/10.3390/cells10010027
The paper
Baj, J., Forma, A., Sitarz, M., Portincasa, P., Garruti, G., Krasowska, D., & Maciejewski, R. (2020). Helicobacter pylori Virulence Factors—Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment. Cells. https://doi.org/10.3390/cells10010027

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.