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Cited by 1,520

The DOI matches its Crossref record; 111 of the 111 references it cites were found in a registry or an index.

Gastric Cancer: Epidemiology, Risk Factors, Classification, Genomic Characteristics and Treatment Strategies

Open access
Machlowska, Julita, Baj, Jacek, Sitarz, Monika, Maciejewski, Ryszard, Sitarz, Robert·2020·International Journal of Molecular Sciences

Abstract

Gastric cancer (GC) is one of the most common malignancies worldwide and it is the fourth leading cause of cancer-related death. GC is a multifactorial disease, where both environmental and genetic factors can have an impact on its occurrence and development. The incidence rate of GC rises progressively with age; the median age at diagnosis is 70 years. However, approximately 10% of gastric carcinomas are detected at the age of 45 or younger. Early-onset gastric cancer is a good model to study genetic alterations related to the carcinogenesis process, as young patients are less exposed to environmental carcinogens. Carcinogenesis is a multistage disease process specified by the progressive development of mutations and epigenetic alterations in the expression of various genes, which are responsible for the occurrence of the disease.

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Metadata

Authors
Machlowska, J., Baj, J., Sitarz, M., Maciejewski, R., & Sitarz, R.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2020-06-04
Volume
21
Issue
11
Pages
4012
ISSN
1422-0067 (ISSN-L)
OpenAlex
W3033366394
Cited by
1,520
References
111
FWCI
91.00
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Gastric Cancer: Epidemiology, Risk Factors, Classification, Genomic Characteristics and Treatment Strategies. https://app.cochat.ai/papers/10.3390/ijms21114012
The paper
Machlowska, J., Baj, J., Sitarz, M., Maciejewski, R., & Sitarz, R. (2020). Gastric Cancer: Epidemiology, Risk Factors, Classification, Genomic Characteristics and Treatment Strategies. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms21114012

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.