The DOI matches its Crossref record; 86 of the 86 references it cites were found in a registry or an index.
Mesenchymal Stem Cell Migration and Tissue Repair
Open accessAbstract
Mesenchymal stem cells (MSCs) are multilineage cells with the ability to self-renew and differentiate into a variety of cell types, which play key roles in tissue healing and regenerative medicine. Bone marrow-derived mesenchymal stem cells (BMSCs) are the most frequently used stem cells in cell therapy and tissue engineering. However, it is prerequisite for BMSCs to mobilize from bone marrow and migrate into injured tissues during the healing process, through peripheral circulation. The migration of BMSCs is regulated by mechanical and chemical factors in this trafficking process. In this paper, we review the effects of several main regulatory factors on BMSC migration and its underlying mechanism; discuss two critical roles of BMSCs—namely, directed differentiation and the paracrine function—in tissue repair; and provide insight into the relationship between BMSC migration and tissue repair, which may provide a better guide for clinical applications in tissue repair through the efficient regulation of BMSC migration.
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1 retracted
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Cited by
Stem cell-based therapy for human diseases
Hoang, D. M., Pham, P. T., Bach, T. Q., Ngo, A. T. L., Nguyen, Q. T., Phan, T. T. K., Nguyen, G. H., Le, P. T. T., Hoang, V. T., Forsyth, N. R., et al. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01134-4 · Cited by 1,074
Calcium Phosphate-Based Biomaterials for Bone Repair
Hou, X., Zhang, L., Zhou, Z., Luo, X., Wang, T., Zhao, X., Lu, B., Chen, F., & Zheng, L. (2022) · Journal of Functional Biomaterials · doi:10.3390/jfb13040187 · Cited by 322
Polarized Macrophages in Periodontitis: Characteristics, Function, and Molecular Signaling
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Chen, X., Zheng, J., Yin, L., Li, Y., & Liu, H. (2024) · Journal of Orthopaedic Surgery and Research · doi:10.1186/s13018-024-04846-1 · Cited by 34
Metadata
- Authors
- Fu, X., Liu, G., Halim, A., Ju, Y., Luo, Q., & Song, G.
- Venue
- Cells
- Publisher
- MDPI AG
- Published
- 2019-07-28
- Volume
- 8
- Issue
- 8
- Pages
- 784
- ISSN
- 2073-4409 (ISSN-L)
- OpenAlex
- W2965698862
- Cited by
- 1,044
- References
- 86
- FWCI
- 47.70
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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