A Deep Learning Model with Self-Supervised Learning and Attention Mechanism for COVID-19 Diagnosis Using Chest X-ray Images
Open accessAbstract
The SARS-CoV-2 virus has spread worldwide, and the World Health Organization has declared COVID-19 pandemic, proclaiming that the entire world must overcome it together. The chest X-ray and computed tomography datasets of individuals with COVID-19 remain limited, which can cause lower performance of deep learning model. In this study, we developed a model for the diagnosis of COVID-19 by solving the classification problem using a self-supervised learning technique with a convolution attention module. Self-supervised learning using a U-shaped convolutional neural network model combined with a convolution block attention module (CBAM) using over 100,000 chest X-Ray images with structure similarity (SSIM) index captures image representations extremely well. The system we proposed consists of fine-tuning the weights of the encoder after a self-supervised learning pretext task, interpreting the chest X-ray representation in the encoder using convolutional layers, and diagnosing the chest X-ray image as the classification model. Additionally, considering the CBAM further improves the averaged accuracy of 98.6%, thereby outperforming the baseline model (97.8%) by 0.8%. The proposed model classifies the three classes of normal, pneumonia, and COVID-19 extremely accurately, along with other metrics such as specificity and sensitivity that are similar to accuracy. The average area under the curve (AUC) is 0.994 in the COVID-19 class, indicating that our proposed model exhibits outstanding classification performance.
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Two of the five self-prediction studies compared their approach to models without self-supervised pre-training and reported slight relative improvements in performance of 1.12% and 0.690%.
“Two of the five studies compared their approach to models without self-supervised pre-training and reported slight relative improvements in performance of 1.12%67 and 0.690%63.”
From Self-supervised learning for medical image classification: a systematic review and implementation guidelines (2023) · cites this paper as [67]
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Cites
Deep Residual Learning for Image Recognition
He, K., Zhang, X., Ren, S., & Sun, J. (2016) · 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR) · doi:10.1109/cvpr.2016.90 · Cited by 235,474 · see citing works
U-Net: Convolutional Networks for Biomedical Image Segmentation
Ronneberger, O., Fischer, P., & Brox, T. (2015) · Lecture notes in computer science · doi:10.1007/978-3-319-24574-4_28 · Cited by 99,404 · see citing works
Very Deep Convolutional Networks for Large-Scale Image Recognition
Simonyan, K., & Zisserman, A. (2014) · arXiv · doi:10.48550/arxiv.1409.1556 · Cited by 74,248 · see citing works
XGBoost: A Scalable Tree Boosting System
Chen, T., & Guestrin, C. (2016) · Proceedings of the 22nd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining · doi:10.1145/2939672.2939785 · Cited by 54,569 · see citing works
You Only Look Once: Unified, Real-Time Object Detection
Redmon, J., Divvala, S., Girshick, R., & Farhadi, A. (2016) · 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR) · doi:10.1109/cvpr.2016.91 · Cited by 53,803 · see citing works
(2014) · Cited by 33,419 · see citing works
MobileNetV2: Inverted Residuals and Linear Bottlenecks
Sandler, M., Howard, A., Zhu, M., Zhmoginov, A., & Chen, L.-C. (2018) · 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition · doi:10.1109/cvpr.2018.00474 · Cited by 28,755 · see citing works
CBAM: Convolutional Block Attention Module
Woo, S., Park, J., Lee, J.-Y., & Kweon, I. S. (2018) · Lecture Notes in Computer Science · doi:10.1007/978-3-030-01234-2_1 · Cited by 25,853 · see citing works
Self-citationGrad-CAM: Visual Explanations from Deep Networks via Gradient-Based Localization
Selvaraju, R. R., Cogswell, M., Das, A., Vedantam, R., Parikh, D., & Batra, D. (2017) · 2017 IEEE International Conference on Computer Vision (ICCV) · doi:10.1109/iccv.2017.74 · Cited by 24,513 · see citing works
Xception: Deep Learning with Depthwise Separable Convolutions
Chollet, F. (2017) · 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR) · doi:10.1109/cvpr.2017.195 · Cited by 20,380 · see citing works
MobileNets: Efficient Convolutional Neural Networks for Mobile Vision Applications
Howard, A. G., Zhu, M., Chen, B., Kalenichenko, D., Wang, W., Weyand, T., Andreetto, M., & Adam, H. (2017) · arXiv · doi:10.48550/arxiv.1704.04861 · Cited by 19,015 · see citing works
Learning Deep Features for Discriminative Localization
Zhou, B., Khosla, A., Lapedriza, A., Oliva, A., & Torralba, A. (2016) · 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR) · doi:10.1109/cvpr.2016.319 · Cited by 11,428 · see citing works
A model of saliency-based visual attention for rapid scene analysis
Itti, L., Christof Koch, A., & Niebur, E. (1998) · IEEE Transactions on Pattern Analysis and Machine Intelligence · doi:10.1109/34.730558 · Cited by 11,289 · see citing works
Identity mappings in deep residual networks
He, K., Zhang, X., Ren, S., & Sun, J. (2016) · Lecture Notes in Computer Science · doi:10.1007/978-3-319-46493-0_38 · Cited by 10,741 · see citing works
Detection of SARS-CoV-2 in Different Types of Clinical Specimens
Wang, W., Xu, Y., Gao, R., Lu, R., Han, K., Wu, G., & Tan, W. (2020) · JAMA · doi:10.1001/jama.2020.3786 · Cited by 5,019 · see citing works
Zhang, R., Isola, P., & Efros, A. A. (2016) · Lecture notes in computer science · doi:10.1007/978-3-319-46487-9_40 · Cited by 3,361 · see citing works
Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR
Fang, Y., Zhang, H., Xie, J., Lin, M., Ying, L., Pang, P., & Ji, W. (2020) · Radiology · doi:10.1148/radiol.2020200432 · Cited by 3,340 · see citing works
Automated detection of COVID-19 cases using deep neural networks with X-ray images
Öztürk, T., Talo, M., Yildirim, E. A., Baloğlu, U. B., Yıldırım, Ö., & Acharya, U. R. (2020) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2020.103792 · Cited by 2,607 · see citing works
The Effectiveness of Data Augmentation in Image Classification using Deep Learning
Perez, L., & Wang, J. (2017) · arXiv · doi:10.48550/arxiv.1712.04621 · Cited by 2,499 · see citing works
Unsupervised Representation Learning by Predicting Image Rotations
Gidaris, S., Singh, P., & Komodakis, N. (2018) · arXiv · doi:10.48550/arxiv.1803.07728 · Cited by 2,477 · see citing works
Narin, A., Kaya, C., & Pamuk, Z. (2021) · Pattern Analysis and Applications · doi:10.1007/s10044-021-00984-y · Cited by 2,054 · see citing works
Data augmentation for improving deep learning in image classification problem
Mikołajczyk, A., & Grochowski, M. (2018) · International Interdisciplinary PhD Workshop (IIPhDW) · doi:10.1109/iiphdw.2018.8388338 · Cited by 1,737 · see citing works
Improved Adam Optimizer for Deep Neural Networks
Zhang, Z. (2018) · International Workshop on Quality of Service · doi:10.1109/iwqos.2018.8624183 · Cited by 1,607 · see citing works
Score-CAM: Score-Weighted Visual Explanations for Convolutional Neural Networks
Wang, H., Wang, Z., Du, M., Yang, F., Zhang, Z., Ding, S., Mardziel, P., & Hu, X. (2020) · IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW) · doi:10.1109/cvprw50498.2020.00020 · Cited by 1,553 · see citing works
Frequency and Distribution of Chest Radiographic Findings in Patients Positive for COVID-19
Wong, H. Y. F., Lam, H. Y. S., Fong, A. H.-T., Leung, S. T., Chin, T. W.-Y., Lo, C. S.-Y., Lui, M. M., Lee, J. C. Y., Chiu, K. W.-H., Chung, T. W., et al. (2020) · Radiology · doi:10.1148/radiol.2020201160 · Cited by 1,485 · see citing works
Regularization Theory and Neural Networks Architectures
Girosi, F., Jones, M., & Poggio, T. (1995) · Neural Computation · doi:10.1162/neco.1995.7.2.219 · Cited by 1,345 · see citing works
CoroNet: A deep neural network for detection and diagnosis of COVID-19 from chest x-ray images
Khan, A. I., Shah, J. L., & Bhat, M. M. (2020) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2020.105581 · Cited by 1,312 · see citing works
Imaging Profile of the COVID-19 Infection: Radiologic Findings and Literature Review
Ng, M., Lee, E. Y. P., Jin, Y., Yang, F., Li, X., Wang, H., Lui, M. M., Lo, C. S.-Y., Leung, B., Khong, P., et al. (2020) · Radiology Cardiothoracic Imaging · doi:10.1148/ryct.2020200034 · Cited by 1,141 · see citing works
Deep-COVID: Predicting COVID-19 from chest X-ray images using deep transfer learning
Minaee, S., Kafieh, R., Milan Sonka, A., Yazdani, S., & Soufi, G. J. (2020) · Medical Image Analysis · doi:10.1016/j.media.2020.101794 · Cited by 1,026 · see citing works
COVID-19 Image Data Collection: Prospective Predictions are the Future
Cohen, J., Morrison, P., Dao, L., Roth, K., Duong, T. Q., & Ghassemi, M. (2020) · The Journal of Machine Learning for Biomedical Imaging · doi:10.59275/j.melba.2020-48g7 · Cited by 1,026 · see citing works
Learning Representations for Automatic Colorization
Larsson, G., Maire, M., & Shakhnarovich, G. (2016) · Lecture Notes in Computer Science · doi:10.1007/978-3-319-46493-0_35 · Cited by 946 · see citing works
Two public chest X-ray datasets for computer-aided screening of pulmonary diseases.
(2014) · PubMed Central · doi:10.3978/j.issn.2223-4292.2014.11.20 · Cited by 918 · see citing works
Deep Learning COVID-19 Features on CXR Using Limited Training Data Sets
Oh, Y., Park, S. J., & Ye, J. C. (2020) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2020.2993291 · Cited by 897 · see citing works
COVID-CAPS: A capsule network-based framework for identification of COVID-19 cases from X-ray images
Afshar, P., Heidarian, S., Naderkhani, F., Oikonomou, A., Plataniotis, K. N., & Mohammadi, A. (2020) · Pattern Recognition Letters · doi:10.1016/j.patrec.2020.09.010 · Cited by 710 · see citing works
Rahimzadeh, M., & Attar, A. (2020) · Informatics in Medicine Unlocked · doi:10.1016/j.imu.2020.100360 · Cited by 695 · see citing works
Using Self-Supervised Learning Can Improve Model Robustness and Uncertainty
Hendrycks, D., Mazeika, M., Kadavath, S., & Song, D. (2019) · arXiv · doi:10.48550/arxiv.1906.12340 · Cited by 634 · see citing works
Zhao, D., Yao, F., Wang, L., Zheng, L., Gao, Y., Ye, J., Guo, F., Zhao, H., & Gao, R. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa247 · Cited by 488 · see citing works
Clinical and CT Imaging Features of the COVID-19 Pneumonia: Focus on Pregnant Women and Children
Liu, H., Liu, F., Li, J., Zhang, T., Wang, D., & Lan, W. (2020) · Journal of Infection · doi:10.1016/j.jinf.2020.03.007 · Cited by 484 · see citing works
Why do deep convolutional networks generalize so poorly to small image transformations?
Azulay, A., & Weiss, Y. (2018) · arXiv · doi:10.48550/arxiv.1805.12177 · Cited by 428 · cited 1× · see citing works
“Furthermore, a global average pooling layer calculates the average values of each feature map, containing more implicative information than a flatten layer and prevents overfitting by reducing trainable parameters [43].”
BackgroundCOVID-ResNet: A Deep Learning Framework for Screening of COVID19 from RadiographsPreprint
Farooq, M. A., & Hafeez, A. B. (2020) · arXiv (Cornell University) · doi:10.48550/arxiv.2003.14395 · Cited by 409 · see citing works
The Impacts of Robotics, Artificial Intelligence On Business and Economics
Dirican, C. (2015) · Procedia - Social and Behavioral Sciences · doi:10.1016/j.sbspro.2015.06.134 · Cited by 402 · see citing works
Automated medical diagnosis of COVID-19 through EfficientNet convolutional neural network
Marques, G., Agarwal, D., & Díez, I. D. L. T. (2020) · Applied Soft Computing · doi:10.1016/j.asoc.2020.106691 · Cited by 401 · see citing works
Models Genesis: Generic Autodidactic Models for 3D Medical Image Analysis
Zhou, Z., Sodha, V., Siddiquee, M. M. R., Feng, R., Tajbakhsh, N., Gotway, M. B., & Liang, J. (2019) · Lecture notes in computer science · doi:10.1007/978-3-030-32251-9_42 · Cited by 327 · see citing works
Estimating the false-negative test probability of SARS-CoV-2 by RT-PCR
Wikramaratna, P. S., Paton, R. S., Ghafari, M., & Lourenço, J. (2020) · Eurosurveillance · doi:10.2807/1560-7917.es.2020.25.50.2000568 · Cited by 313 · see citing works
Rahaman, M. M., Li, C., Yao, Y., Kulwa, F., Rahman, M. A., Wang, Q., Qi, S., Kong, F., Zhu, X., & Zhao, X. (2020) · Journal of X-Ray Science and Technology · doi:10.3233/xst-200715 · Cited by 302 · see citing works
Hassantabar, S., Ahmadi, M., & Sharifi, A. (2020) · Chaos Solitons & Fractals · doi:10.1016/j.chaos.2020.110170 · Cited by 276 · see citing works
Automatic Detection of Acute Bacterial Pneumonia from Chest X-ray Reports
Fiszman, M., Chapman, W. W., Aronsky, D., Evans, R. S., & Haug, P. J. (2000) · Journal of the American Medical Informatics Association · doi:10.1136/jamia.2000.0070593 · Cited by 250 · see citing works
Ouchicha, C., Ammor, O., & Meknassi, M. (2020) · Chaos Solitons & Fractals · doi:10.1016/j.chaos.2020.110245 · Cited by 217 · see citing works
OptCoNet: an optimized convolutional neural network for an automatic diagnosis of COVID-19
Goel, T., Murugan, R., Mirjalili, S., & Chakrabartty, D. K. (2020) · Applied Intelligence · doi:10.1007/s10489-020-01904-z · Cited by 178 · see citing works
Artificial intelligence in engineering
Pham, D. T., & Pham, P. T. N. (1999) · International Journal of Machine Tools and Manufacture · doi:10.1016/s0890-6955(98)00076-5 · Cited by 157 · see citing works
Rate Bounds on SSIM Index of Quantized Images
Channappayya, S. S., Bovik, A. C., & Heath, R. W. (2008) · IEEE Transactions on Image Processing · doi:10.1109/tip.2008.2001400 · Cited by 133 · see citing works
Lee, K.-S., Kim, J., Jeon, E., Choi, W. S., Kim, N. H., & Lee, K. Y. (2020) · Journal of Personalized Medicine · doi:10.3390/jpm10040213 · Cited by 68 · see citing works
Improving Coronavirus (COVID-19) Diagnosis using Deep Transfer LearningPreprint
Rehman, A., Naz, S., Khan, A., Zaib, A., & Razzak, I. (2020) · medRxiv · doi:10.1101/2020.04.11.20054643 · Cited by 64 · see citing works
Detection of Pneumonia in chest X-ray images
Parveen, N. R. S., & Sathik, M. M. (2011) · Journal of X-Ray Science and Technology · doi:10.3233/xst-2011-0304 · Cited by 62 · see citing works
COVID-19 Prognosis via Self-Supervised Representation Learning and Multi-Image PredictionPreprint
Sriram, A., Muckley, M. J., Sinha, K., Shamout, F. E., Pineau, J., Geras, K. J., Azour, L., Aphinyanaphongs, Y., Yakubova, N., & Moore, W. H. (2021) · PubMed · doi:10.48550/arxiv.2101.04909 · Cited by 50 · see citing works
Bi-Level Prediction Model for Screening COVID-19 Patients Using Chest X-Ray Images
Das, S., Roy, S. D., Malakar, S., et al. (2021) · Big Data Research · doi:10.1016/j.bdr.2021.100233 · Cited by 30 · see citing works
Batch-normalized Mlpconv-wise supervised pre-training network in network
Han, X., & Dai, Q. (2017) · Applied Intelligence · doi:10.1007/s10489-017-0968-2 · Cited by 22 · see citing works
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Research works printed but not linked: 1
- Zhai, X.; Oliver, A.; Kolesnikov, A.; Beyer, L. S4l: Self-supervised semi-supervised learning. In Proceedings of the IEEE International Conference on Computer Vision, Seoul, Korea, 27 October-3 November 2019; pp. 1476-1485
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Sorted by citations
Huang, S.-C., Pareek, A., Jensen, M., Lungren, M. P., Yeung, S., & Chaudhari, A. S. (2023) · npj Digital Medicine · doi:10.1038/s41746-023-00811-0 · Cited by 479 · see citing works
“Two of the fi ve studies compared their approach to models without self-supervised pre-training and reported slight relative improvements in performance of 1.12% 67 and 0.690% 63 .”
BackgroundResultInfluential
- Authors
- Park, J., Kwak, I.-Y., & Lim, C.
- Affiliations
- Chung-Ang University (KR)
- Corresponding author
- Lim, Changwon
- Venue
- Electronics
- Publisher
- MDPI AG
- Published
- 2021-08-18
- Volume
- 10
- Issue
- 16
- Pages
- 1996
- ISSN
- 2079-9292 (ISSN-L)
- OpenAlex
- W3193757158
- Cited by
- 24
- References
- 57
- Citations by year
- 2025: 10 · 2024: 3 · 2023: 4 · 2022: 7
- FWCI
- 1.86
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Electronics (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Research Foundation of Korea (NRF-2017M3C4A7083281, 2020R1C1C1A01013020)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › COVID-19 diagnosis using AI
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Advanced Neural Network Applications
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Keywords
- COVID-19 diagnosis, chest X-ray images, self-supervised learning, attention mechanism, convolution block attention module, structural similarity, pneumonia classification, encoder fine-tuning, medical image classification
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