The DOI matches its Crossref record; 113 of the 113 references it cites were found in a registry or an index.
The Value of Reference Genomes in the Conservation of Threatened Species
Open accessAbstract
Conservation initiatives are now more crucial than ever—over a million plant and animal species are at risk of extinction over the coming decades. The genetic management of threatened species held in insurance programs is recommended; however, few are taking advantage of the full range of genomic technologies available today. Less than 1% of the 13505 species currently listed as threated by the International Union for Conservation of Nature (IUCN) have a published genome. While there has been much discussion in the literature about the importance of genomics for conservation, there are limited examples of how having a reference genome has changed conservation management practice. The Tasmanian devil (Sarcophilus harrisii), is an endangered Australian marsupial, threatened by an infectious clonal cancer devil facial tumor disease (DFTD). Populations have declined by 80% since the disease was first recorded in 1996. A reference genome for this species was published in 2012 and has been crucial for understanding DFTD and the management of the species in the wild. Here we use the Tasmanian devil as an example of how a reference genome has influenced management actions in the conservation of a species.
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“High-quality reference genome assemblies are increasingly recognized as an important foundation of conservation genomics84–91.”
From Chromosomal-level reference genome assembly of muskox (Ovibos moschatus) from Banks Island in the Canadian Arctic, a resource for conservation genomics (2024) · cites this paper as [88]
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Cites
Accelerated modern human–induced species losses: Entering the sixth mass extinction
Ceballos, G., Ehrlich, P. R., Barnosky, A. D., García, A., Pringle, R. M., & Palmer, T. M. (2015) · Science Advances · doi:10.1126/sciadv.1400253 · Cited by 4,220 · cited 1×
“We are currently in the midst of a global sixth mass extinction event, with biodiversity rapidly declining around the world [1], and extinction rates are accelerating [2].”
BackgroundPeterson, B. K., Weber, J. N., Delaney, E., Fisher, H. S., & Hoekstra, H. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037135 · Cited by 3,766
Genome-wide genetic marker discovery and genotyping using next-generation sequencing
Davey, J. W., Hohenlohe, P. A., Etter, P. D., Boone, J. Q., Catchen, J., & Blaxter, M. (2011) · Nature Reviews Genetics · doi:10.1038/nrg3012 · Cited by 2,489
PacBio Sequencing and its Applications
Rhoads, A., & Au, K. F. (2015) · Genomics, Proteomics & Bioinformatics · doi:10.1016/j.gpb.2015.08.002 · Cited by 2,135
Microsatellites for ecologists: a practical guide to using and evaluating microsatellite markers.
Selkoe, K., & Toonen, R. (2006) · Ecology Letters · doi:10.1111/j.1461-0248.2006.00889.x · Cited by 1,814
Harnessing the power of RADseq for ecological and evolutionary genomics
Andrews, K. R., Good, J. M., Miller, M. R., Luikart, G., & Hohenlohe, P. A. (2016) · Nature Reviews Genetics · doi:10.1038/nrg.2015.28 · Cited by 1,509
Analyses of pig genomes provide insight into porcine demography and evolution
Groenen, M. A. M., Archibald, A. L., Uenishi, H., Tuggle, C. K., Takeuchi, Y., Rothschild, M. F., Rogel-Gaillard, C., Park, C., Milan, D., Megens, H., et al. (2012) · Nature · doi:10.1038/nature11622 · Cited by 1,424
Introduction to Conservation Genetics
Frankham, R., Ballou, J. D., & Briscoe, D. A. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511809002 · Cited by 1,271
The sequence and de novo assembly of the giant panda genome
Li, R., Fan, W., Tian, G., Zhu, H., He, L., Cai, J., Huang, Q., Cai, Q., Li, B., Bai, Y., et al. (2010) · Nature · doi:10.1038/nature08696 · Cited by 1,180
Noninvasive genetic sampling: look before you leap
Taberlet, P., Waits, L. P., & Luikart, G. (1999) · Trends in Ecology & Evolution · doi:10.1016/s0169-5347(99)01637-7 · Cited by 1,110
Research works printed but not linked: 4
- Potter, 2017, Oz Mammal Genomics, Australas. Sci., 38, 19
- Grueber, C.E., Chong, R., Gooley, R.M., McLennan, E.A., Barrs, V.R., Belov, K., and Hogg, C.J. Genetic analysis of scat samples to inform conservation of Tasmanian devil. Aust. Zool., (In press).
- Hogg, C.J., McLennan, E.A., Wise, P., Lee, A., Pemberton, D., Fox, S., Belov, K., and Grueber, C.E. Preserving the integrity of a single source population during multiple translocations. Biol. Conserv., (In press).
- McLennan, E.A., Grueber, C.E., Wise, P., Belov, K., and Hogg, C.J. Mixing genetic lineages sucessfully boosts diversity of an endangered carnivore. Anim. Conserv., (under review).
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How genomics can help biodiversity conservation
Theissinger, K., Fernandes, C., Formenti, G., Bista, I., Berg, P. R., Bleidorn, C., Bombarely, A., Crottini, A., Gallo, G. R., Godoy, J. A., et al. (2023) · Trends in Genetics · doi:10.1016/j.tig.2023.01.005 · Cited by 401
The era of reference genomes in conservation genomics
Formenti, G., Theissinger, K., Fernandes, C., Bista, I., Bombarely, A., Bleidorn, C., Ciofi, C., Crottini, A., Godoy, J. A., Höglund, J., et al. (2022) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2021.11.008 · Cited by 340
Opportunities and challenges of macrogenetic studies
Leigh, D. M., van Rees, C. B., Millette, K. L., Breed, M. F., Schmidt, C., Bertola, L. D., Hand, B. K., Hunter, M. E., Jensen, E. L., Kershaw, F., et al. (2021) · Nature Reviews Genetics · doi:10.1038/s41576-021-00394-0 · Cited by 127
The phenotypic costs of captivity
Crates, R., Stojanović, D., & Heinsohn, R. (2022) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12913 · Cited by 115
Metadata
- Authors
- Brandies, P., Peel, E., Hogg, C. J., & Belov, K.
- Affiliations
- The University of Sydney (AU)
- Corresponding author
- Belov, Katherine
- Venue
- Genes
- Publisher
- MDPI AG
- Published
- 2019-10-25
- Volume
- 10
- Issue
- 11
- Pages
- 846
- ISSN
- 2073-4425 (ISSN-L)
- PMC
- PMC6895880
- OpenAlex
- W2981549736
- Cited by
- 158
- References
- 113
- Citations by year
- 2026: 16 · 2025: 29 · 2024: 25 · 2023: 28 · 2022: 24 · 2021: 22 · 2020: 11 · 2019: 1
- FWCI
- 1.95
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Genes (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Australian Research Council (LP140100508, DP180102465)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Health Sciences › Veterinary › Small Animals › Veterinary Oncology Research
- Keywords
- reference genome, conservation genomics, threatened species, Tasmanian devil, devil facial tumour disease, insurance population, genetic management, extinction risk, marsupials
- MeSH terms
- Animals, Marsupialia, Reference Standards, Genome, Genomics, Endangered Species, Genotyping Techniques
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