Effects of Indoor Air Pollutants on Atopic Dermatitis
Open accessAbstract
The increasing prevalence of atopic dermatitis (AD) is associated with variations in indoor environments. In Korea, many inner walls of homes are covered with wallpaper: such walls emit indoor air pollutants, including volatile organic compounds (VOCs) and formaldehyde. This randomized, double-blind study investigated the effects of wallpaper on indoor air quality and AD. Thirty-one children (aged three to eight years) with moderate AD were assigned to environmentally-friendly (EF) and polyvinyl chloride (PVC) wallpaper groups. Indoor air concentrations of VOCs, natural VOCs (NVOCs), formaldehyde, and total suspended bacteria were measured before and two (W2) and eight weeks (W8) after wallpapering. Scoring Atopic Dermatitis (SCORAD) evaluations and blood tests were performed during the same period. The EF wallpaper and PVC wallpaper groups showed similar trends in the changes in total VOCs (TVOC) and formaldehyde content in the indoor air. However, the EF wallpaper group showed more improvement on the SCORAD at W2 and W8 than the PVC wallpaper group. The SCORAD index was positively correlated with several indoor air pollutants. Further, the SCORAD index and NVOC % were negatively correlated. Improved SCORAD index and effects of wallpapering on indoor air quality improvements occurred within a short period of time in both groups. We believe that NVOCs in indoor air after EF wallpapering have a beneficial effect on health.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Indoor air pollution from cooking accelerated skin aging in Chinese women, and atopic dermatitis increased from other indoor pollutants, such as PVCs from wallpaper.
“indoor air pollution from cooking accelerated skin aging in Chinese women, and atopic dermatitis increased from other indoor pollutants, such as polyvinyl chloride (PVCs) from wallpaper [51,52]”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Diagnostic features of atopic dermatitis
Hanifin, J. M., & Rajka, G. (1980) · Acta Dermato-Venereologica · doi:10.2340/00015555924447 · Cited by 5,086 · see citing works
International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods
Asher, M., Keil, U., Anderson, H., Beasley, R., Crane, J., Martinez, F., Mitchell, E., Pearce, N., Sibbald, B., Stewart, A., et al. (1995) · European Respiratory Journal · doi:10.1183/09031936.95.08030483 · Cited by 3,724 · see citing works
Severity Scoring of Atopic Dermatitis: The SCORAD Index
(2009) · Dermatology · doi:10.1159/000247298 · Cited by 2,282 · see citing works
Treatment of Childhood Atopic Dermatitis and Economic Burden of Illness in Asia Pacific Countries
Lee, B. W., & Detzel, P. R. (2015) · Annals of Nutrition and Metabolism · doi:10.1159/000370221 · Cited by 1,671 · see citing works
Mendell, M. J. (2007) · Indoor Air · doi:10.1111/j.1600-0668.2007.00478.x · Cited by 438 · see citing works
The role of air pollutants in atopic dermatitis
Ahn, K. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.09.023 · Cited by 337 · see citing works
Eosinophils and atopic dermatitis
Simon, D., Braathen, L. R., & Simon, H. (2004) · Allergy · doi:10.1111/j.1398-9995.2004.00476.x · Cited by 325 · see citing works
Domestic exposure to formaldehyde significantly increases the risk of asthma in young children
Rumchev, K. B., Spickett, J. T., Bulsara, M. K., Phillips, M. R., & Stick, S. M. (2002) · European Respiratory Journal · doi:10.1183/09031936.02.00245002 · Cited by 309 · see citing works
Increased risk of allergy in children due to formaldehyde exposure in homes
Garrett, M., Hooper, M., Hooper, B., Rayment, P., & Abramson, M. J. (1999) · Allergy · doi:10.1034/j.1398-9995.1999.00763.x · Cited by 215 · see citing works
Does Exposure to Indoor Allergens Contribute to the Development of Asthma and Allergy?
Arshad, S. H. (2009) · Current Allergy and Asthma Reports · doi:10.1007/s11882-009-0082-6 · Cited by 129 · see citing works
Role of Reactive Oxygen Species in the Regulation of Physiological Functions.
Nose, K. (2000) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.23.897 · Cited by 116 · see citing works
Lehmann, I., Rehwagen, M., Diez, U., Seiffart, A., Rolle-Kampczyk, U. E., Richter, M., Wetzig, H., Borte, M., & Herbarth, O. (2001) · International Journal of Hygiene and Environmental Health · doi:10.1078/1438-4639-00100 · Cited by 111 · see citing works
Takeda, M., Saijo, Y., Yuasa, M., Kanazawa, A., Araki, A., & Kishi, R. (2009) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-009-0395-8 · Cited by 106 · see citing works
Huss‐Marp, J., Eberlein-König, B., Breuer, K., Mair, S., Ansel, A., Darsow, U. G., Krämer, U., Mayer, E., Ring, J., & Behrendt, H. (2006) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2006.02448.x · Cited by 106 · see citing works
Influences of environmental chemicals on atopic dermatitis.
Kim, K. (2015) · Toxicological Research · doi:10.5487/tr.2015.31.2.089 · Cited by 85 · see citing works
Symptom definitions for SBS (sick building syndrome) in residential dwellings
Wang, B.-L., Takigawa, T., Yamasaki, Y., Sakano, N., Wang, D.-H., & Ogino, K. (2007) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2007.03.004 · Cited by 79 · see citing works
Ahn, K., Kim, J., Kwon, H., Chae, Y., Hahm, M., Lee, K., Park, Y. M., Lee, S., Han, M. Y., & Kim, W. K. (2011) · Journal of Korean Medical Association · doi:10.5124/jkma.2011.54.7.769 · Cited by 74 · see citing works
Self-citationLee, J., Lee, H., Park, M. R., Lee, S.-W., Kim, E., Cho, J. B., Kim, J., Han, Y., Jung, K., Cheong, H., et al. (2014) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2014.6.6.517 · Cited by 58 · see citing works
Self-citationHalmerbauer, G., Frischer, T., & Roller, D. (1997) · Allergy · doi:10.1111/j.1398-9995.1997.tb01236.x · Cited by 48 · see citing works
A triterpene from Rubus pinfaensis
Durham, D. G., Liu, X., & Richards, R. M. E. (1994) · Phytochemistry · doi:10.1016/s0031-9422(00)89744-7 · Cited by 42 · see citing works
Indoor Volatile Organic Compounds in Atopy Patients' Houses in South Korea
Choi, D. W., Moon, K. W., Byeon, S. H., Lee, E. I., Sul, D. G., Lee, J. H., Oh, E. H., & Kim, Y. H. (2009) · Indoor and Built Environment · doi:10.1177/1420326x08101945 · Cited by 23 · see citing works
Behavior of VOCs and Carbonyl Compounds Emission from Different Types of Wallpapers in Korea
Lim, J., Kim, S., Kim, A., Lee, W., Han, J., & Cha, J.-S. (2014) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph110404326 · Cited by 19 · see citing works
Na, J., Byun, S. Y., Jeong, M. Y., Park, K. C., & Huh, C. (2014) · Annals of Dermatology · doi:10.5021/ad.2014.26.6.688 · Cited by 5 · see citing works
Characteristics of pollutant emission from wallpapers - Around TVOC and HCHO -
Jang, S.-K., Kim, M., Lee, H.-S., Lim, J.-H., Jang, M., & Seo, S. (2005) · Analytical Science and Technology · Cited by 3 · see citing works
Kim, G., Kwon, C., 염동걸, Joung, D., Choi, Y. H., & Park, B. (2014) · 한국산림과학회지(구 한국임학회지) · doi:10.14578/jkfs.2014.103.3.483 · Cited by 3 · see citing works
Yoo, B. H., & 박용승 (2006) · Cited by 3 · see citing works
Flagged first, then by citations
2 of the 28 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
The impact of airborne pollution on atopic dermatitis: a literature review
Hendricks, A. J., Eichenfield, L. F., & Shi, V. Y. (2019) · British Journal of Dermatology · doi:10.1111/bjd.18781 · Cited by 103 · see citing works
Porous cellulose nanofiber stringed HKUST-1 polyhedron membrane for air purification
Zhao, X., Chen, L., Guo, Y. F., Ma, X., Li, Z., Wen, Y., & Peng, X. (2018) · Applied Materials Today · doi:10.1016/j.apmt.2018.11.012 · Cited by 76 · see citing works
Impact of climate change on atopic dermatitis: A review by the International Eczema Council
Wang, S., Stefanovic, N., Orfali, R. L., Aoki, V., Brown, S. J., Dhar, S., Eichenfield, L. F., Flohr, C., Ha, A., Mora, C., et al. (2024) · Allergy · doi:10.1111/all.16007 · Cited by 51 · see citing works
Dai, L., Li, X., Zhang, L., Ma, P., Guan, J., & Yu, W. (2022) · Advanced Composites and Hybrid Materials · doi:10.1007/s42114-021-00398-8 · Cited by 40 · see citing works
Comparison of Pollutant Effects on Cutaneous Inflammasomes Activation
Ivarsson, J., Ferrara, F., Vallese, A., Guiotto, A., Colella, S., Pecorelli, A., & Valacchi, G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242316674 · Cited by 37 · see citing works
Bae, S., & Kwon, H. (2019) · Yonsei Medical Journal · doi:10.3349/ymj.2019.60.3.243 · Cited by 31 · see citing works
Kim, S. H., Lee, J., Oh, I., Oh, Y., Sim, C. S., Bang, J.-H., Park, J., & Kim, Y. (2021) · PLoS ONE · doi:10.1371/journal.pone.0248624 · Cited by 27 · see citing works
Lu, C., Jiang, Y., Lan, M., Wang, L., Zhang, W., & Wang, F. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.134506 · Cited by 24 · see citing works
Suzuki, N., Nakaoka, H., Nakayama, Y., Tsumura, K., Takaguchi, K., Takaya, K., Eguchi, A., Hanazato, M., Todaka, E., & Mori, C. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.141635 · Cited by 23 · see citing works
The clinical, mechanistic, and social impacts of air pollution on atopic dermatitis
Zeldin, J., Ratley, G., Shobnam, N., & Myles, I. A. (2024) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2024.07.027 · Cited by 22 · see citing works
Personal Exposure to Total VOC Is Associated With Symptoms of Atopic Dermatitis in Schoolchildren
Ha, E. K., Kim, J. H., Park, D., Lee, E., Lee, S. W., Jee, H. M., Shin, Y. H., & Han, M. Y. (2022) · Journal of Korean Medical Science · doi:10.3346/jkms.2022.37.e63 · Cited by 19 · see citing works
Self-citationLiang, H., Zhao, S., & Su, Y. (2018) · International Journal of Environmental Research · doi:10.1007/s41742-018-0096-9 · Cited by 17 · see citing works
Liu, S., Qiu, J. H., Han, L., Ma, X., & Chen, W. (2022) · Polymers · doi:10.3390/polym14091795 · Cited by 15 · see citing works
Lee, J., Yun, S., Oh, I., Kim, M. H., & Kim, Y. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17238831 · Cited by 14 · see citing works
Exposure to Volatile Organic Compounds May Contribute to Atopic Dermatitis in Adults
Tang, K., Chen, Y.-S., Lee, M.-F., Chen, T., Lai, C., Lin, C., & Chen, Y. (2024) · Biomedicines · doi:10.3390/biomedicines12071419 · Cited by 12 · see citing works
Zhu, R., Chen, R., Duo, Y., Zhang, S., Xie, D., & Mei, Y. (2019) · Polymers · doi:10.3390/polym11010086 · Cited by 9 · see citing works
Kim, S. H., Yu, S. Y., Choo, J. H., Kim, J. K., Kim, J., Ahn, K., & Hwang, S. Y. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252312827 · Cited by 4 · see citing works
Self-citationIndoor air pollution and atopic diseases: a comprehensive framework
Ridolo, E., Pederzani, A., Barone, A., Ottoni, M., Crivellaro, M., & Nicoletta, F. (2024) · doi:10.37349/eaa.2024.00038 · Cited by 4 · see citing works
Dermatitis, a nightmare for those exposed to environmental pollutants
Khoshakhlagh, A. H., Mohammadzadeh, M., & Gruszecka‐Kosowska, A. (2024) · Journal of Hazardous Materials Advances · doi:10.1016/j.hazadv.2024.100454 · Cited by 4 · see citing works
Home Remodeling and Food Allergy Interact Synergistically to Increase the Risk of Atopic Dermatitis
Lee, W. S., Lee, K. S., Lee, S., Sung, M., Lee, S.-J., Jee, H. M., Sheen, Y. H., Han, M. Y., & Jung, Y.-H. (2017) · BioMed Research International · doi:10.1155/2017/3793679 · Cited by 4 · see citing works
The home environment and current dermatitis in Japanese junior high school children in Kansai area
Takaoka, M., Suzuki, K., & Norbäck, D. (2022) · Indoor and Built Environment · doi:10.1177/1420326x211061855 · Cited by 4 · see citing works
Biomarkers and their Clinical Applications in Pediatrics
Elgörmüş, Y. (2022) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815040463122010019 · Cited by 3 · see citing works
Practical issues of emollient use in winter for patients with atopic dermatitis: expert resolution
Fedenko, E. S., Zakharova, I. N., Zaytseva, O. V., Pampura, A. N., Murashkin, N. N., & Litovkina, A. O. (2024) · Russian Journal of Allergy · doi:10.36691/rja16981 · Cited by 3 · see citing works
Ka, Y., & Ji, K. (2021) · Korean Journal of Environmental Health Sciences · doi:10.5668/jehs.2021.47.6.505 · Cited by 3 · see citing works
Oxidative Stress, Environmental Factors, and Pollutants
Hendricks, A. J., Thompson, A. M., & Shi, V. Y. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-84744-5.00009-7 · Cited by 3 · see citing works
Schneider, E., Butter, K., Schnautz, B., Musiol, S., Grosch, J., Schindela, S., Garcia‐Käufer, M., Gminski, R., Haak, S., Ohlmeyer, M., et al. (2025) · Experimental Dermatology · doi:10.1111/exd.70086 · Cited by 1 · see citing works
Atopik dermatitte biyo belirteç olarak eozinofil ve IgE.
Özkars, M. Y. (2018) · Zeynep Kamil Tıp Bülteni · doi:10.16948/zktipb.403247 · Cited by 1 · see citing works
Why Outcome Measures in Dermatology Are Becoming Patient Centric
Nergard, J. C., Siddiqui, F., Kailas, A., Winslow, M., & Solomon, J. A. (2017) · Current Dermatology Reports · doi:10.1007/s13671-017-0187-4 · Cited by 1 · see citing works
Функціональний стан гіпофізарно-тиреоїдної системи в дітей з алергодерматозами
Sorokman, Т. V., Lozyuk, I. Y., Daalder, L., & Ostapchuk, V. G. (2017) · INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine) · doi:10.22141/2224-0721.13.8.2017.119274
Formaldehyde and VOC Emissions from EFBMF Panel for Sound Absorption Material
Malaysia, U. T. H. O., & Samsudin, E. M. (2019) · International Journal of Advanced Trends in Computer Science and Engineering · doi:10.30534/ijatcse/2019/5181.32019
Study on the Characteristics of Formaldehyde Pollution in Typical Teaching Machine Room
Yang, P., Meng, M., Gao, D., Lin, Z., Ding, H. D., Tian, M., Chen, C., Zhou, Z., Huang, S., & Kang, C. (2020) · E3S Web of Conferences · doi:10.1051/e3sconf/202014302001
Multifunctional Gas Cleaning Membranes
Zhong, Z., & Xing, W. (2025) · Springer eBooks · doi:10.1007/978-981-96-1144-7_7
Targeting Pollutants in the Treatment and Prevention of Atopic Dermatitis
Shobnam, N., & Myles, I. A. (2025) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2025.06.002
- Authors
- Kim, J., Kim, H., Lim, D., Lee, Y.-K., & Kim, J.
- Affiliations
- Department of Pediatrics, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon-si, Gangwon-do 24341, Korea
- Department of Pediatrics, Inha University School of Medicine, 100 Inha-ro, Nam-gu, Incheon 22212, Korea
- Inha University (KR)
- Seoul National University (KR)
- Kangwon National University (KR)
- Corresponding author
- Kim, Jeong
- Venue
- International Journal of Environmental Research and Public Health
- Publisher
- MDPI AG
- Published
- 2016-12-09
- Volume
- 13
- Issue
- 12
- Pages
- 1220
- ISSN
- 1660-4601 (ISSN-L)
- PMC
- PMC5201361
- OpenAlex
- W2267632729
- Cited by
- 34
- References
- 28
- Citations by year
- 2025: 3 · 2024: 8 · 2023: 1 · 2022: 6 · 2021: 2 · 2020: 3 · 2019: 4 · 2018: 4 · 2017: 3
- FWCI
- 2.30
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Environmental Research and Public Health (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Inha University
- Korea Environmental Industry and Technology Institute
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Indoor Air Quality and Microbial Exposure
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
- Keywords
- atopic dermatitis, indoor air quality, wallpaper, volatile organic compounds, formaldehyde, children, SCORAD, indoor air pollutants
- MeSH terms
- Air Pollutants, Child, Child, Preschool, Construction Materials, Dermatitis, Atopic, Double-Blind Method, Environmental Monitoring, Female, Formaldehyde, Humans, Male, Polyvinyl Chloride, Ventilation, Air Pollution, Indoor, Volatile Organic Compounds, Republic of Korea
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
