The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Overview of Cotinine Cutoff Values for Smoking Status Classification
Open accessAbstract
While cotinine is commonly used as a biomarker to validate self-reported smoking status, the selection of an optimal cotinine cutoff value for distinguishing true smokers from true nonsmokers shows a lack of standardization among studies. This review describes how the cutoff values have been derived, and explains the issues involved in the generalization of a cutoff value. In this study, we conducted an English-language literature search in PubMed using the keywords “cotinine” and “cutoff” or “self-reported” and “smoking status” and “validation” for the years 1985–2014. We obtained 104 articles, 32 of which provided (1) sensitivity and specificity of a cutoff value and (2) determination methods for the given cutoff value. We found that the saliva cotinine cutoff value range of 10–25 ng/mL, serum and urine cotinine cutoff of 10–20 ng/mL and 50–200 ng/mL, respectively, have been commonly used to validate self-reported smoking status using a 2 × 2 table or a receiver operating characteristics (ROC) curve. We also found that recent large population-based studies in the U.S. and UK reported lower cutoff values for cotinine in serum (3 ng/mL) and saliva (12 ng/mL), compared to the traditionally accepted ones (15 and 14 ng/mg, respectively).
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Performance of plasma trigonelline as a marker of coffee consumption in an epidemiologic setting
Midttun, Ø., Ulvik, A., Nygård, O., & Ueland, P. M. (2018) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy059 · Cited by 50
Minatoya, M., Araki, A., Itoh, S., Yamazaki, K., Kobayashi, S., Miyashita, C., Sasaki, S., & Kishi, R. (2019) · Environmental Health and Preventive Medicine · doi:10.1186/s12199-019-0834-4 · Cited by 43
Zhang, Y., Mustieles, V., Sun, Y., Oulhote, Y., Wang, Y.-X., & Messerlian, C. (2022) · Environment International · doi:10.1016/j.envint.2022.107239 · Cited by 39
Trends in Vitamin C consumption in the United States: 1999-2018
Brauchla, M., Dekker, M. J., & Rehm, C. D. (2021) · Nutrients · doi:10.3390/nu13020420 · Cited by 35
Silva, A. I., Camelo, A., Madureira, J., Reis, A. T., Machado, A. P., Teixeira, J. P., & Costa, C. (2022) · Environmental Research · doi:10.1016/j.envres.2021.111827 · Cited by 13
Metadata
- Authors
- Kim, S.
- Venue
- International Journal of Environmental Research and Public Health
- Publisher
- MDPI AG
- Published
- 2016-12-14
- Volume
- 13
- Issue
- 12
- Pages
- 1236
- ISSN
- 1660-4601 (ISSN-L)
- OpenAlex
- W2564037959
- Cited by
- 304
- References
- 53
- FWCI
- 16.43
- Type
- journal article
- Language
- en
- Open access
- gold
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