Association between malnutrition assessed by the global leadership initiative on malnutrition criteria and mortality in older people: a scoping review
Open accessAbstract
The Global Leadership Initiative on Malnutrition (GLIM) criteria were introduced in 2018 for the diagnosis of malnutrition in adults. This review was aimed at gathering the evidence about the association between malnutrition according to the GLIM criteria and mortality in older people, an emerging and clinically meaningful topic in the implementation of the GLIM criteria in geriatric healthcare settings. This scoping review considered meta-analyses, systematic reviews, cohort studies, and cross-sectional studies published in PubMed, Scopus, and the Cochrane Database for Systematic Reviews from the development of the GLIM criteria in 2018 to January 2023. Seventeen articles (15 cohort and 2 cross-sectional studies) were included. The association between GLIM criteria and mortality had been assessed in hospitalized (11 over the 17 articles) and community-dwelling older populations, and those in nursing homes. The review found a strong association between malnutrition according to GLIM criteria and mortality in hospitalized (1.2-fold to 7-fold higher mortality) and community-dwelling older people (1.6-fold to 4-fold higher mortality). These findings highlight the prognostic value of the GLIM criteria and support strategies towards the implementation of malnutrition evaluation according to the GLIM, in order to optimize comprehensive geriatric assessment and provide older people with the highest quality of nutritional care. Studies in nursing home populations were very scarce and may be urgently required.
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The systematic reviews included studies conducted in hospital settings, among community-dwelling older adults, and in nursing homes.
“The SRs included studies conducted in hospital settings, 14 among community‐dwelling older adults, 15 and in nursing homes. 15”
From GLIM consensus approach to diagnosis of malnutrition: A 5‐year update (2025) · cites this paper as [15]
The Results report that this review included studies of hospitalized, community-dwelling, and nursing-home older adults. However, the Discussion calls it a scoping review and notes its non-systematic nature, so describing this source as a systematic review is not supported. (LLM, conf=0.89)
Experimental — accuracy not yet measuredEight systematic reviews, some with meta-analyses, of predictive validity (mainly mortality as the outcome) were published.
“Concurrently, eight SRs, some with meta‐analyses, of predictive validity (mainly mortality as the outcome) were published (Table 1). 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21”
From GLIM consensus approach to diagnosis of malnutrition: A 5‐year update (2025) · cites this paper as [15]
The Discussion (page unavailable) says this review examines whether the GLIM criteria predict death in older people, supporting its inclusion as a review of predictive validity with mortality as the outcome. But the same section explicitly calls the review non-systematic, so this source does not support counting it as a systematic review. The claim that there were eight reviews depends on the other cited works, not this paper alone. (LLM, conf=0.88)
Experimental — accuracy not yet measuredAmong hospitalized patients with malnutrition, there was a 1.2- to 7.2-fold increase in mortality over 4 months; among nursing home patients, 1.3- to 4.7-fold over 1 or 2 years; among community settings, 1.6- to 4.4-fold over 2-14 years.
“Among hospitalized patients with malnutrition, there was a 1.2‐ to 7.2‐fold increase in mortality over 4 months; among nursing home patients with malnutrition, there was a 1.3‐ to 4.7‐fold increase in mortality over 1 or 2 years; and finally, among patients in community settings with malnutrition, there was a 1.6‐ to 4.4‐fold increase in mortality over 2–14 years. 15”
From GLIM consensus approach to diagnosis of malnutrition: A 5‐year update (2025) · cites this paper as [15]
The Results section reports associations close to the cited ranges for hospitalized and community-dwelling older people. For nursing-home residents, however, it reports HRs of 1.37–2.41, not an increase up to 4.7-fold. It also gives hospital-study follow-up periods of 4 months to 8 years, rather than a common 4-month period. (LLM, conf=0.91)
Experimental — accuracy not yet measured
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- Authors
- Sánchez-Rodríguez, D., De Meester, D., Minon, L., Claessens, M., Gümüs, N., Lieten, S., Benoit, F., Surquin, M., & Marco, E.
- Affiliations
- Geriatrics Department, Brugmann University Hospital, Université Libre de Bruxelles, Place A. Van Gehuchten 4, 1020 Brussels, Belgium
- Department of Geriatrics, Onze Lieve Vrouw Ziekehuis (OLV) Aalst, Moorselbaan 164, 9300 Aalst, Belgium
- Université Libre de Bruxelles (BE)
- Universitair Ziekenhuis Brussel (BE)
- Universitat Pompeu Fabra (ES)
- ORCID
- Venue
- International Journal of Environmental Research and Public Health
- Publisher
- MDPI AG
- Published
- 2023-03-30
- Volume
- 20
- Issue
- 7
- Pages
- 5320
- ISSN
- 1660-4601 (ISSN-L)
- PMC
- PMC10094645
- OpenAlex
- W4361278155
- Cited by
- 32
- References
- 40
- Citations by year
- 2026: 7 · 2025: 13 · 2024: 11 · 2023: 1
- FWCI
- 1.14
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Environmental Research and Public Health (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Repositori digital de la UPF (Universitat Pompeu Fabra) (acceptedVersion, cc-by)
- Open Repository and Bibliography (University of Liège) (submittedVersion, other-oa)
- VUBIR (Vrije Universiteit Brussel) (submittedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Keywords
- malnutrition, GLIM criteria, mortality, older adults, hospitalized older adults, community-dwelling older adults, nursing homes, prognostic value, geriatric assessment, dietary management, malnutrition screening
- MeSH terms
- Systematic Reviews as Topic, Adult, Aged, Cross-Sectional Studies, Humans, Leadership, Nursing Homes, Nutritional Status, Nutrition Assessment, Malnutrition
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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