Cited by 32Nutrition and Health in AgingClinical Nutrition and GastroenterologyFrailty in Older Adults

Association between malnutrition assessed by the global leadership initiative on malnutrition criteria and mortality in older people: a scoping review

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Sánchez-Rodríguez, Dolores, De Meester, Dorien, Minon, Léa, Claessens, Marie, Gümüs, Neslian, Lieten, Siddhartha, Benoit, Florence, Surquin, Murielle +1 more·2023·International Journal of Environmental Research and Public Health

Abstract

The Global Leadership Initiative on Malnutrition (GLIM) criteria were introduced in 2018 for the diagnosis of malnutrition in adults. This review was aimed at gathering the evidence about the association between malnutrition according to the GLIM criteria and mortality in older people, an emerging and clinically meaningful topic in the implementation of the GLIM criteria in geriatric healthcare settings. This scoping review considered meta-analyses, systematic reviews, cohort studies, and cross-sectional studies published in PubMed, Scopus, and the Cochrane Database for Systematic Reviews from the development of the GLIM criteria in 2018 to January 2023. Seventeen articles (15 cohort and 2 cross-sectional studies) were included. The association between GLIM criteria and mortality had been assessed in hospitalized (11 over the 17 articles) and community-dwelling older populations, and those in nursing homes. The review found a strong association between malnutrition according to GLIM criteria and mortality in hospitalized (1.2-fold to 7-fold higher mortality) and community-dwelling older people (1.6-fold to 4-fold higher mortality). These findings highlight the prognostic value of the GLIM criteria and support strategies towards the implementation of malnutrition evaluation according to the GLIM, in order to optimize comprehensive geriatric assessment and provide older people with the highest quality of nutritional care. Studies in nursing home populations were very scarce and may be urgently required.

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Crossref · 10.3390/ijerph20075320

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  • The systematic reviews included studies conducted in hospital settings, among community-dwelling older adults, and in nursing homes.

    “The SRs included studies conducted in hospital settings, 14 among community‐dwelling older adults, 15 and in nursing homes. 15”

    From GLIM consensus approach to diagnosis of malnutrition: A 5‐year update (2025) · cites this paper as [15]

    The Results report that this review included studies of hospitalized, community-dwelling, and nursing-home older adults. However, the Discussion calls it a scoping review and notes its non-systematic nature, so describing this source as a systematic review is not supported. (LLM, conf=0.89)

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  • Eight systematic reviews, some with meta-analyses, of predictive validity (mainly mortality as the outcome) were published.

    “Concurrently, eight SRs, some with meta‐analyses, of predictive validity (mainly mortality as the outcome) were published (Table 1). 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21”

    From GLIM consensus approach to diagnosis of malnutrition: A 5‐year update (2025) · cites this paper as [15]

    The Discussion (page unavailable) says this review examines whether the GLIM criteria predict death in older people, supporting its inclusion as a review of predictive validity with mortality as the outcome. But the same section explicitly calls the review non-systematic, so this source does not support counting it as a systematic review. The claim that there were eight reviews depends on the other cited works, not this paper alone. (LLM, conf=0.88)

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  • Among hospitalized patients with malnutrition, there was a 1.2- to 7.2-fold increase in mortality over 4 months; among nursing home patients, 1.3- to 4.7-fold over 1 or 2 years; among community settings, 1.6- to 4.4-fold over 2-14 years.

    “Among hospitalized patients with malnutrition, there was a 1.2‐ to 7.2‐fold increase in mortality over 4 months; among nursing home patients with malnutrition, there was a 1.3‐ to 4.7‐fold increase in mortality over 1 or 2 years; and finally, among patients in community settings with malnutrition, there was a 1.6‐ to 4.4‐fold increase in mortality over 2–14 years. 15”

    From GLIM consensus approach to diagnosis of malnutrition: A 5‐year update (2025) · cites this paper as [15]

    The Results section reports associations close to the cited ranges for hospitalized and community-dwelling older people. For nursing-home residents, however, it reports HRs of 1.37–2.41, not an increase up to 4.7-fold. It also gives hospital-study follow-up periods of 4 months to 8 years, rather than a common 4-month period. (LLM, conf=0.91)

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Authors
Sánchez-Rodríguez, D., De Meester, D., Minon, L., Claessens, M., Gümüs, N., Lieten, S., Benoit, F., Surquin, M., & Marco, E.
Affiliations
  • Geriatrics Department, Brugmann University Hospital, Université Libre de Bruxelles, Place A. Van Gehuchten 4, 1020 Brussels, Belgium
  • Department of Geriatrics, Onze Lieve Vrouw Ziekehuis (OLV) Aalst, Moorselbaan 164, 9300 Aalst, Belgium
  • Université Libre de Bruxelles (BE)
  • Universitair Ziekenhuis Brussel (BE)
  • Universitat Pompeu Fabra (ES)
Venue
International Journal of Environmental Research and Public Health
Publisher
MDPI AG
Published
2023-03-30
Volume
20
Issue
7
Pages
5320
ISSN
1660-4601 (ISSN-L)
OpenAlex
W4361278155
Cited by
32
References
40
Citations by year
2026: 7 · 2025: 13 · 2024: 11 · 2023: 1
FWCI
1.14
Type
journal article
Language
en
Open access
Locations
  • International Journal of Environmental Research and Public Health (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Repositori digital de la UPF (Universitat Pompeu Fabra) (acceptedVersion, cc-by)
  • Open Repository and Bibliography (University of Liège) (submittedVersion, other-oa)
  • VUBIR (Vrije Universiteit Brussel) (submittedVersion)
  • RePEc: Research Papers in Economics (submittedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
Keywords
malnutrition, GLIM criteria, mortality, older adults, hospitalized older adults, community-dwelling older adults, nursing homes, prognostic value, geriatric assessment, dietary management, malnutrition screening
MeSH terms
Systematic Reviews as Topic, Adult, Aged, Cross-Sectional Studies, Humans, Leadership, Nursing Homes, Nutritional Status, Nutrition Assessment, Malnutrition

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