Muscle loss: The new malnutrition challenge in clinical practice
Open accessAbstract
Recent definitions of malnutrition include low muscle mass within its diagnostic criteria. In fact, malnutrition is one of the main risk factors of skeletal muscle loss contributing to the onset of sarcopenia. However, differences in the screening and diagnosis of skeletal muscle loss, especially as a result of malnutrition in clinical and community settings, still occur mainly as techniques and thresholds used vary in clinical practice. The objectives of this position paper are firstly to emphasize the link between skeletal muscle loss and malnutrition-related conditions and secondly to raise awareness for the timely identification of loss of skeletal muscle mass and function in high risk populations. Thirdly to recognize the need to implement appropriate nutritional strategies for prevention and treatment of skeletal muscle loss and malnutrition across the healthcare continuum. Malnutrition needs to be addressed clinically as a muscle-related disorder and clinicians should integrate nutritional assessment with muscle mass measurements for optimal evaluation of these two interrelated entities to tailor interventions appropriately. The design of monitoring/evaluation and discharge plans need to include multimodal interventions with nutrition and physical exercise that are key to preserve patient's muscle mass and function in clinical and community settings.
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Adequate nutrition is essential for the maintenance of muscle mass.
“Adequate nutrition is essential for the maintenance of muscle mass.”
From Strategies for minimizing muscle loss during use of incretin‐mimetic drugs for treatment of obesity (2025) · cites this paper as [63]
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- Authors
- Landi, F., Camprubi-Robles, M., Bear, D. E., Cederholm, T., Malafarina, V., Welch, A. A., & Cruz-Jentoft, A. J.
- Affiliations
- Università Cattolica del Sacro Cuore (IT)
- St Thomas' Hospital (GB)
- Uppsala University (SE)
- Complejo Hospitalario de Navarra (ES)
- University of East Anglia (GB)
- Instituto Ramón y Cajal de Investigación Sanitaria (ES)
- Corresponding author
- Landi, F.
- Bear, D.E.
- Cederholm, T.
- Malafarina, V.
- Welch, A.A.
- Cruz-Jentoft, A.J.
- Venue
- Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2019-10
- Volume
- 38
- Issue
- 5
- Pages
- 2113-2120
- ISSN
- 0261-5614 (ISSN-L)
- OpenAlex
- W2903073296
- Semantic Scholar
- 77927824550cab3c08379c64535abb3c9c98ef95
- Cited by
- 235
- References
- 79
- Citations by year
- 2026: 19 · 2025: 36 · 2024: 35 · 2023: 24 · 2022: 40 · 2021: 33 · 2020: 34 · 2019: 14
- FWCI
- 13.88
- Type
- journal article
- Language
- en
- Open access
- green
- ueaeprints.uea.ac.uk
- Locations
- Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- UEA Digital Repository (University of East Anglia) (acceptedVersion)
- Research Portal (King's College London) (submittedVersion, cc-by-nc-nd)
- Funders
- Dairy Australia
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Keywords
- muscle mass loss, sarcopenia, malnutrition, skeletal muscle mass, muscle function, nutritional assessment, malnutrition screening, dietary intervention, physical activity, multimodal intervention, discharge planning, vulnerable populations
- MeSH terms
- Adult, Aged, Aging, Continuity of Patient Care, Humans, Middle Aged, Nutritional Status, Nutrition Assessment, Muscle, Skeletal, Malnutrition, Sarcopenia
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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