The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Mechanisms of Regulation of the Chemokine-Receptor Network
Open accessAbstract
The interactions of chemokines with their G protein-coupled receptors promote the migration of leukocytes during normal immune function and as a key aspect of the inflammatory response to tissue injury or infection. This review summarizes the major cellular and biochemical mechanisms by which the interactions of chemokines with chemokine receptors are regulated, including: selective and competitive binding interactions; genetic polymorphisms; mRNA splice variation; variation of expression, degradation and localization; down-regulation by atypical (decoy) receptors; interactions with cell-surface glycosaminoglycans; post-translational modifications; oligomerization; alternative signaling responses; and binding to natural or pharmacological inhibitors.
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Crump, M. P., Gong, J., Loetscher, P., Rajarathnam, K., Amara, A., Arenzana‐Seisdedos, F., Virelizier, J., Baggiolini, M., Sykes, B. D., & Clark‐Lewis, I. (1997) · The EMBO Journal · doi:10.1093/emboj/16.23.6996 · Cited by 731 · cited 1×
“The recent structures of chemokine-bound receptors [13,14], in addition to several structures of chemokines bound to receptor fragments [20–22], have confirmed two central aspects of the popular “two-site model” for chemokine-receptor interactions [23] (Figure 3c).”
BackgroundTuning inflammation and immunity by chemokine sequestration: decoys and more
Mantovani, A., Bonecchi, R., & Locati, M. (2006) · Nature Reviews Immunology · doi:10.1038/nri1964 · Cited by 481
Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity
Smith, P., Fallon, R. E., Mangan, N. E., Walsh, C. M., Saraiva, M., Sayers, J. R., McKenzie, A. N. J., Alcami, A., & Fallon, P. G. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20050955 · Cited by 160
Cited by
Mesenchymal stem/stromal cells in cancer therapy
Lan, T., Luo, M., & Wei, X. (2021) · Journal of Hematology & Oncology · doi:10.1186/s13045-021-01208-w · Cited by 374
The role of chemokines and chemokine receptors in multiple sclerosis
Cui, L.-Y., Chu, S.-F., & Chen, N.-H. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.106314 · Cited by 135
Yin, X., Wang, Z., Wu, T., Ma, M., Zhang, Z., Chu, Z., Hu, Q., Ding, H., Han, X., Xu, J., et al. (2019) · Journal of Translational Medicine · doi:10.1186/s12967-019-02172-3 · Cited by 54
Zhao, Y.-C., Hu, T., Chen, Y., & Du, K.-T. (2019) · Balkan Medical Journal · doi:10.4274/balkanmedj.galenos.2019.2019.6.47 · Cited by 9
Metadata
- Authors
- Stone, M., Hayward, J., Huang, C., E. Huma, Z., & Sanchez, J.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2017-02-07
- Volume
- 18
- Issue
- 2
- Pages
- 342
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2586779720
- Cited by
- 275
- References
- 3
- FWCI
- 11.31
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
