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Cited by 293

The DOI matches its Crossref record; 165 of the 165 references it cites were found in a registry or an index.

When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in Glioma

Open access
Roesch, Saskia, Rapp, Carmen, Dettling, Steffen, Herold-Mende, Christel·2018·International Journal of Molecular Sciences

Abstract

As a substantial part of the brain tumor microenvironment (TME), glioma-associated microglia/macrophages (GAMs) have an emerging role in tumor progression and in controlling anti-tumor immune responses. We review challenges and improvements of cell models and highlight the contribution of this highly plastic cell population to an immunosuppressive TME, besides their well-known functional role regarding glioma cell invasion and angiogenesis. Finally, we summarize first therapeutic interventions to target GAMs and their effect on the immunobiology of gliomas, focusing on their interaction with T cells.

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Crossref · 10.3390/ijms19020436

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Metadata

Authors
Roesch, S., Rapp, C., Dettling, S., & Herold-Mende, C.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2018-02-01
Volume
19
Issue
2
Pages
436
ISSN
1422-0067 (ISSN-L)
OpenAlex
W2791477629
Cited by
293
References
165
FWCI
12.82
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in Glioma. https://app.cochat.ai/papers/10.3390/ijms19020436
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Roesch, S., Rapp, C., Dettling, S., & Herold-Mende, C. (2018). When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in Glioma. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms19020436

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.