The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Apoptosis: A Target for Anticancer Therapy
Open accessAbstract
Apoptosis, the cell’s natural mechanism for death, is a promising target for anticancer therapy. Both the intrinsic and extrinsic pathways use caspases to carry out apoptosis through the cleavage of hundreds of proteins. In cancer, the apoptotic pathway is typically inhibited through a wide variety of means including overexpression of antiapoptotic proteins and under-expression of proapoptotic proteins. Many of these changes cause intrinsic resistance to the most common anticancer therapy, chemotherapy. Promising new anticancer therapies are plant-derived compounds that exhibit anticancer activity through activating the apoptotic pathway.
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1 retracted
Apoptosis and Molecular Targeting Therapy in Cancer
Hassan, M., Watari, H., AbuAlmaaty, A., Ohba, Y., & Sakuragi, N. (2014) · BioMed Research International · doi:10.1155/2014/150845 · Cited by 1,121
RetractedApoptosis: A Review of Programmed Cell Death
Elmore, S. (2007) · Toxicologic Pathology · doi:10.1080/01926230701320337 · Cited by 13,853
The Bcl-2 Protein Family: Arbiters of Cell Survival
Adams, J. M., & Cory, S. (1998) · Science · doi:10.1126/science.281.5381.1322 · Cited by 5,332
Danial, N. N., & Korsmeyer, S. J. (2004) · Cell · doi:10.1016/s0092-8674(04)00046-7 · Cited by 4,651
Green, D. R., & Llambi, F. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a006080 · Cited by 1,101
Bcl-2 family proteins and cancer
Yip, K. W., & Reed, J. C. (2008) · Oncogene · doi:10.1038/onc.2008.307 · Cited by 881
Mitochondrial apoptosis: killing cancer using the enemy within
Lopez, J., & Tait, S. W. G. (2015) · British Journal of Cancer · doi:10.1038/bjc.2015.85 · Cited by 784
Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively?
Ravindran, J., Prasad, S., & Aggarwal, B. B. (2009) · The AAPS Journal · doi:10.1208/s12248-009-9128-x · Cited by 768
Molecular Mechanisms of Apoptosis and Roles in Cancer Development and Treatment
Goldar, S., Khaniani, M. S., Derakhshan, S. M., & Baradaran, B. (2015) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2015.16.6.2129 · Cited by 606
Heger, M., van Golen, R. F., Broekgaarden, M., & Michel, M. C. (2014) · Pharmacological Reviews · doi:10.1124/pr.110.004044 · Cited by 576
Cited by
Mustafa, M., Ahmad, R., Tantry, I. Q., Ahmad, W., Siddiqui, S., Alam, M., Abbas, K., Moinuddin, Hassan, M. I., Habib, S., et al. (2024) · Cells · doi:10.3390/cells13221838 · Cited by 595
Mc Larney, B. E., Sonay, A. Y., Apfelbaum, E., Mostafa, N., Monette, S., Goerzen, D., Aguirre, N., Exner, R. M., Habjan, C., Isaac, E., et al. (2024) · Nature Biomedical Engineering · doi:10.1038/s41551-024-01248-w · Cited by 28
Proapoptotic and proautophagic activity of 20-hydroxyecdysone in breast cancer cells in vitro
Romaniuk-Drapała, A., Lisiak, N., Totoń, E., Matysiak, A., Nawrot, J., Nowak, G., Kaczmarek, M., Rybczyńska, M., & Rubiś, B. (2021) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2021.109479 · Cited by 27
Metadata
- Authors
- Pfeffer, C., & Singh, A.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2018-02-02
- Volume
- 19
- Issue
- 2
- Pages
- 448
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2793972506
- Cited by
- 1,542
- References
- 42
- FWCI
- 39.39
- Type
- journal article
- Language
- en
- Open access
- gold
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
