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BIOPEP-UWM Database of Bioactive Peptides: Current Opportunities
Open accessAbstract
The BIOPEP-UWM™ database of bioactive peptides (formerly BIOPEP) has recently become a popular tool in the research on bioactive peptides, especially on these derived from foods and being constituents of diets that prevent development of chronic diseases. The database is continuously updated and modified. The addition of new peptides and the introduction of new information about the existing ones (e.g., chemical codes and references to other databases) is in progress. New opportunities include the possibility of annotating peptides containing D-enantiomers of amino acids, batch processing option, converting amino acid sequences into SMILES code, new quantitative parameters characterizing the presence of bioactive fragments in protein sequences, and finding proteinases that release particular peptides.
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“Libraries of bioactive peptide sequences obtained via proteolysis of food proteins are widely available in databases like BIOPEP-UWM and contain modules of in silico proteolysis, activity prediction, and structure-function analysis [209].”
From Navigating the potential of algal peptides: health effects, market applications, and scientific challenges (2026) · cites this paper as [209]
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“Biological informatics platforms based on machine learning and artificial intelligence (AI) have transformed the field of peptide studies by allowing predictions of bioactivity, toxicity, physicochemical properties, and possible health impact within hours.”
From Navigating the potential of algal peptides: health effects, market applications, and scientific challenges (2026) · cites this paper as [209]
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David, L., Thakkar, A., Mercado, R., & Engkvist, O. (2020) · Journal of Cheminformatics · doi:10.1186/s13321-020-00460-5 · Cited by 587
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Current Trends of Bioactive Peptides—New Sources and Therapeutic Effect
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Metadata
- Authors
- Minkiewicz, P., Iwaniak, A., & Darewicz, M.
- Affiliations
- Chair of Food Biochemistry, University of Warmia and Mazury in Olsztyn, Plac Cieszyński 1, 10-726 Olsztyn-Kortowo, Poland
- University of Warmia and Mazury in Olsztyn (PL)
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2019-11-27
- Volume
- 20
- Issue
- 23
- Pages
- 5978
- ISSN
- 1422-0067 (ISSN-L)
- PMC
- PMC6928608
- OpenAlex
- W2989775272
- Cited by
- 958
- References
- 104
- Citations by year
- 2026: 161 · 2025: 189 · 2024: 156 · 2023: 160 · 2022: 135 · 2021: 103 · 2020: 53 · 2019: 1
- FWCI
- 24.15
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- International Journal of Molecular Sciences (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- The project was financially supported by the Minister of Science and Higher Education in the range of the program entitled “Regional Initiative of Excellence” for the years 2019–2022, amount of funding 12,000,000 PLN (010/RID/2018/19)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Protein Hydrolysis and Bioactive Peptides
- Physical Sciences › Chemistry › Organic Chemistry › Chemical Synthesis and Analysis
- Life Sciences › Immunology and Microbiology › Microbiology › Antimicrobial Peptides and Activities
- Keywords
- bioactive peptides, peptide database, food-derived peptides, chronic disease prevention, D-enantiomer, peptide annotation
- MeSH terms
- Amino Acid Sequence, Amino Acids, Animals, Humans, Peptide Hydrolases, Peptides, Databases, Factual
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