The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Advances in Analysis of Biodistribution of Exosomes by Molecular Imaging
Open accessAbstract
Exosomes are nano-sized membranous vesicles produced by nearly all types of cells. Since exosome-like vesicles are produced in an evolutionarily conserved manner for information and function transfer from the originating cells to recipient cells, an increasing number of studies have focused on their application as therapeutic agents, drug delivery vehicles, and diagnostic targets. Analysis of the in vivo distribution of exosomes is a prerequisite for the development of exosome-based therapeutics and drug delivery vehicles with accurate prediction of therapeutic dose and potential side effects. Various attempts to evaluate the biodistribution of exosomes obtained from different sources have been reported. In this review, we examined the current trends and the advantages and disadvantages of the methods used to determine the biodistribution of exosomes by molecular imaging. We also reviewed 29 publications to compare the methods employed to isolate, analyze, and label exosomes as well as to determine the biodistribution of labeled exosomes.
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Cites
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Tumour exosome integrins determine organotropic metastasis
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Advances in therapeutic applications of extracellular vesicles
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Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy
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Cited by
Exosomes: Large-scale production, isolation, drug loading efficiency, and biodistribution and uptake
Kimiz-Gebologlu, I., & Oncel, S. S. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.05.027 · Cited by 722
Biodistribution of extracellular vesicles following administration into animals: A systematic review
Kang, M., Jordan, V., Blenkiron, C., & Chamley, L. W. (2021) · Journal of Extracellular Vesicles · doi:10.1002/jev2.12085 · Cited by 485
Wang, C., Tsai, T., & Lee, C. (2024) · Clinical and Translational Science · doi:10.1111/cts.13904 · Cited by 280
Zhang, L., Lin, J., Xiang, K., Shi, T., & Guo, B. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.10.033 · Cited by 26
Exosomes and Biomaterials: In Search of a New Therapeutic Strategy for Multiple Sclerosis
Ojeda-Hernández, D. D., Hernández-Sapiéns, M. A., Reza-Zaldívar, E. E., Canales-Aguirre, A., Matías-Guiu, J. A., Matías-Guiu, J., Mateos-Díaz, J. C., Gómez-Pinedo, U., & Sancho-Bielsa, F. (2022) · Life · doi:10.3390/life12091417 · Cited by 25
Metadata
- Authors
- Yi, Y. W., Lee, J. H., Kim, S.-Y., Pack, C.-G., Ha, D. H., Park, S. R., Youn, J., & Cho, B. S.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2020-01-19
- Volume
- 21
- Issue
- 2
- Pages
- 665
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W3000102939
- Cited by
- 190
- References
- 10
- FWCI
- 8.92
- Type
- journal article
- Language
- en
- Open access
- gold
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- Yi, Y. W., Lee, J. H., Kim, S.-Y., Pack, C.-G., Ha, D. H., Park, S. R., Youn, J., & Cho, B. S. (2020). Advances in Analysis of Biodistribution of Exosomes by Molecular Imaging. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms21020665
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
