The DOI matches its Crossref record; 150 of the 150 references it cites were found in a registry or an index.
Ambient Air Pollution Increases the Risk of Cerebrovascular and Neuropsychiatric Disorders through Induction of Inflammation and Oxidative Stress
Open accessAbstract
Exposure to ambient air pollution is a well-established determinant of health and disease. The Lancet Commission on pollution and health concludes that air pollution is the leading environmental cause of global disease and premature death. Indeed, there is a growing body of evidence that links air pollution not only to adverse cardiorespiratory effects but also to increased risk of cerebrovascular and neuropsychiatric disorders. Despite being a relatively new area of investigation, overall, there is mounting recent evidence showing that exposure to multiple air pollutants, in particular to fine particles, may affect the central nervous system (CNS) and brain health, thereby contributing to increased risk of stroke, dementia, Parkinson’s disease, cognitive dysfunction, neurodevelopmental disorders, depression and other related conditions. The underlying molecular mechanisms of susceptibility and disease remain largely elusive. However, emerging evidence suggests inflammation and oxidative stress to be crucial factors in the pathogenesis of air pollution-induced disorders, driven by the enhanced production of proinflammatory mediators and reactive oxygen species in response to exposure to various air pollutants. From a public health perspective, mitigation measures are urgent to reduce the burden of disease and premature mortality from ambient air pollution.
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Cites
1 retracted
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The Lancet Commission on pollution and health
Landrigan, P. J., Fuller, R., Acosta, N. J. R., Adeyi, O., Arnold, R., Basu, N. (., Baldé, A. B., Bertollini, R., Bose-O'Reilly, S., Boufford, J. I., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(17)32345-0 · Cited by 4,929
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
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Cited by
Particulate pollution and its toxicity to fish: An overview
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Metadata
- Authors
- Hahad, O., Lelieveld, J., Birklein, F., Lieb, K., Daiber, A., & Münzel, T.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2020-06-17
- Volume
- 21
- Issue
- 12
- Pages
- 4306
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W3035710790
- Cited by
- 432
- References
- 150
- FWCI
- 16.81
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: Ambient Air Pollution Increases the Risk of Cerebrovascular and Neuropsychiatric Disorders through Induction of Inflammation and Oxidative Stress. https://app.cochat.ai/papers/10.3390/ijms21124306
- The paper
- Hahad, O., Lelieveld, J., Birklein, F., Lieb, K., Daiber, A., & Münzel, T. (2020). Ambient Air Pollution Increases the Risk of Cerebrovascular and Neuropsychiatric Disorders through Induction of Inflammation and Oxidative Stress. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms21124306
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
