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Cited by 299

The DOI matches its Crossref record; 187 of the 187 references it cites were found in a registry or an index.

Tissue-Specific Decellularization Methods: Rationale and Strategies to Achieve Regenerative Compounds

Open access
Mendibil, Unai, Ruiz-Hernandez, Raquel, Retegi-Carrion, Sugoi, Garcia-Urquia, Nerea, Olalde-Graells, Beatriz, Abarrategi, Ander·2020·International Journal of Molecular Sciences

Abstract

The extracellular matrix (ECM) is a complex network with multiple functions, including specific functions during tissue regeneration. Precisely, the properties of the ECM have been thoroughly used in tissue engineering and regenerative medicine research, aiming to restore the function of damaged or dysfunctional tissues. Tissue decellularization is gaining momentum as a technique to obtain potentially implantable decellularized extracellular matrix (dECM) with well-preserved key components. Interestingly, the tissue-specific dECM is becoming a feasible option to carry out regenerative medicine research, with multiple advantages compared to other approaches. This review provides an overview of the most common methods used to obtain the dECM and summarizes the strategies adopted to decellularize specific tissues, aiming to provide a helpful guide for future research development.

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Metadata

Authors
Mendibil, U., Ruiz-Hernandez, R., Retegi-Carrion, S., Garcia-Urquia, N., Olalde-Graells, B., & Abarrategi, A.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2020-07-30
Volume
21
Issue
15
Pages
5447
ISSN
1422-0067 (ISSN-L)
OpenAlex
W3045665724
Cited by
299
References
187
FWCI
29.57
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Tissue-Specific Decellularization Methods: Rationale and Strategies to Achieve Regenerative Compounds. https://app.cochat.ai/papers/10.3390/ijms21155447
The paper
Mendibil, U., Ruiz-Hernandez, R., Retegi-Carrion, S., Garcia-Urquia, N., Olalde-Graells, B., & Abarrategi, A. (2020). Tissue-Specific Decellularization Methods: Rationale and Strategies to Achieve Regenerative Compounds. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms21155447

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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