The DOI matches its Crossref record; 186 of the 186 references it cites were found in a registry or an index.
Advances in Growth Factor Delivery for Bone Tissue Engineering
Open accessAbstract
Shortcomings related to the treatment of bone diseases and consequent tissue regeneration such as transplants have been addressed to some extent by tissue engineering and regenerative medicine. Tissue engineering has promoted structures that can simulate the extracellular matrix and are capable of guiding natural bone repair using signaling molecules to promote osteoinduction and angiogenesis essential in the formation of new bone tissues. Although recent studies on developing novel growth factor delivery systems for bone repair have attracted great attention, taking into account the complexity of the extracellular matrix, scaffolding and growth factors should not be explored independently. Consequently, systems that combine both concepts have great potential to promote the effectiveness of bone regeneration methods. In this review, recent developments in bone regeneration that simultaneously consider scaffolding and growth factors are covered in detail. The main emphasis in this overview is on delivery strategies that employ polymer-based scaffolds for spatiotemporal-controlled delivery of both single and multiple growth factors in bone-regeneration approaches. From clinical applications to creating alternative structural materials, bone tissue engineering has been advancing constantly, and it is relevant to regularly update related topics.
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Cites
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Self-citationApplication of decellularized bone matrix as a bioscaffold in bone tissue engineering
Amirazad, H., Dadashpour, M., & Zarghami, N. (2022) · Journal of Biological Engineering · doi:10.1186/s13036-021-00282-5 · Cited by 154
MOFs and bone: application of MOFs in bone tissue engineering and bone diseases
Li, X., Shu, X., Shi, Y., Li, H., & Pei, X. (2023) · Chinese Chemical Letters · doi:10.1016/j.cclet.2022.107986 · Cited by 65
Metadata
- Authors
- Oliveira, É. R., Nie, L., Podstawczyk, D., Allahbakhsh, A., Ratnayake, J., Brasil, D. L., & Shavandi, A.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2021-01-18
- Volume
- 22
- Issue
- 2
- Pages
- 903
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W3125837796
- Cited by
- 258
- References
- 186
- FWCI
- 10.29
- Type
- journal article
- Language
- en
- Open access
- gold
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- Oliveira, É. R., Nie, L., Podstawczyk, D., Allahbakhsh, A., Ratnayake, J., Brasil, D. L., & Shavandi, A. (2021). Advances in Growth Factor Delivery for Bone Tissue Engineering. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms22020903
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
