The DOI matches its Crossref record; 91 of the 91 references it cites were found in a registry or an index.
Osteoblast Differentiation and Signaling: Established Concepts and Emerging Topics
Open accessAbstract
Osteoblasts, the cells that build up our skeleton, are remarkably versatile and important cells that need tight regulation in all the phases of their differentiation to guarantee proper skeletal development and homeostasis. Although we know many of the key pathways involved in osteoblast differentiation and signaling, it is becoming clearer and clearer that this is just the tip of the iceberg, and we are constantly discovering novel concepts in osteoblast physiology. In this review, we discuss well-established pathways of osteoblastic differentiation, i.e., the classical ones committing mesenchymal stromal cells to osteoblast, and then osteocytes as well as recently emerged players. In particular, we discuss micro (mi)RNAs, long non-coding (lnc)RNAs, circular (circ)RNAs, and extracellular vesicles, focusing on the mechanisms through which osteoblasts are regulated by these factors, and conversely, how they use extracellular vesicles to communicate with the surrounding microenvironment.
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1 retracted
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RetractedShedding light on the cell biology of extracellular vesicles
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Oncomirs—MicroRNAs with a role in cancer
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Bone: Formation by Autoinduction
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Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation
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Origins and Mechanisms of miRNAs and siRNAs
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Novel Regulators of Bone Formation: Molecular Clones and Activities
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circRNA biogenesis competes with pre-mRNA splicing
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Cited by
The Metabolic Features of Osteoblasts: Implications for Multiple Myeloma (MM) Bone Disease
Lungu, O., Toscani, D., Burroughs-Garcia, J., & Giuliani, N. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054893 · Cited by 10
Metadata
- Authors
- Ponzetti, M., & Rucci, N.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2021-06-22
- Volume
- 22
- Issue
- 13
- Pages
- 6651
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W3174998679
- Cited by
- 282
- References
- 91
- FWCI
- 10.33
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
