What Is New in Metabolic Dysfunction-Associated Steatotic Liver Disease in Lean Individuals: From Bench to Bedside

A multisociety Delphi consensus statement on new fatty liver disease nomenclature

Rinella, M. E., Lazarus, J. V., Ratziu, V., Francque, S. M., Sanyal, A. J., Kanwal, F., Romero, D., Abdelmalek, M. F., Anstee, Q. M., Arab, J. P., et al. (2023) · Hepatology · doi:10.1097/hep.0000000000000520 · Cited by 3,476 · see citing works

The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review

Younossi, Z. M., Golabi, P., Paik, J. M., Henry, A., Van Dongen, C., & Henry, L. (2023) · Hepatology · doi:10.1097/hep.0000000000000004 · Cited by 3,383 · see citing works

A multisociety Delphi consensus statement on new fatty liver disease nomenclature

Rinella, M. E., Lazarus, J. V., Ratziu, V., Francque, S. M., Sanyal, A. J., Kanwal, F., Romero, D., Abdelmalek, M. F., Anstee, Q. M., Arab, J. P., et al. (2023) · Journal of Hepatology · doi:10.1016/j.jhep.2023.06.003 · Cited by 3,100 · see citing works

AASLD practice guidance on the clinical assessment and management of nonalcoholic fatty liver disease

Rinella, M. E., Neuschwander-Tetri, B. A., Siddiqui, M. S., Abdelmalek, M. F., Caldwell, S., Barb, D., Kleiner, D. E., & Loomba, R. (2023) · Hepatology · doi:10.1097/hep.0000000000000323 · Cited by 2,667 · cited 1× · see citing works

Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity

Ross, R., Neeland, I. J., Yamashita, S., Shai, I., Seidell, J., Magni, P., Santos, R. D., Arsenault, B., Cuevas, A., Hu, F. B., et al. (2020) · Nature Reviews Endocrinology · doi:10.1038/s41574-019-0310-7 · Cited by 1,966 · see citing works

Metabolic syndrome: pathophysiology, management, and modulation by natural compounds

Rochlani, Y. M., Pothineni, N. V. K., Kovelamudi, S., & Mehta, J. L. (2017) · Therapeutic Advances in Cardiovascular Disease · doi:10.1177/1753944717711379 · Cited by 1,103 · see citing works

Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis

Ye, Q., Zou, B., Yeo, Y. H., Li, J., Huang, D. Q., Wu, Y., Yang, H., Liu, C., Kam, L. Y., Tan, X. X. E., et al. (2020) · The Lancet Gastroenterology & Hepatology · doi:10.1016/s2468-1253(20)30077-7 · Cited by 925 · see citing works

Nonalcoholic Steatohepatitis Is the Most Rapidly Increasing Indication for Liver Transplantation in the United States

Younossi, Z. M., Stepanova, M., Ong, J. P., Trimble, G., Alqahtani, S. A., Younossi, I. M., Ahmed, A., Racila, A., & Henry, L. L. (2020) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2020.05.064 · Cited by 586 · see citing works

Multifaceted Physiological Roles of Adiponectin in Inflammation and Diseases

Choi, H. M., Doss, H. M., & Kim, K. S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21041219 · Cited by 520 · see citing works

Leptin in the interplay of inflammation, metabolism and immune system disorders

Abella, V., Scotece, M., Conde, J., Pino, J., González-Gay, M. Á., Gómez-Reino, J. J., Mera, A., Lago, F., Gómez, R., & Gualillo, O. (2017) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2016.209 · Cited by 497 · see citing works

Relationship between sarcopenia and physical activity in older people: a systematic review and meta-analysis

Šteffl, M., Bohannon, R. W., Sontáková, L., Tufano, J. J., Shiells, K. R., & Holmerová, I. (2017) · Clinical Interventions in Aging · doi:10.2147/cia.s132940 · Cited by 480 · see citing works

Can we use old NAFLD data under the new MASLD definition?

Song, S. J., Lai, J. C.-T., Wong, G. L.-H., Wong, V. W.-S., & Yip, T. C.-F. (2024) · Journal of Hepatology · doi:10.1016/j.jhep.2023.07.021 · Cited by 374 · see citing works

Histological severity and clinical outcomes of nonalcoholic fatty liver disease in nonobese patients

Leung, J. C., Loong, T. C., Wei, J. L., Wong, G. L., Chan, A. W. H., Choi, P. C., Shu, S. S., Chim, A. M., Chan, H. L., & Wong, V. W. (2016) · Hepatology · doi:10.1002/hep.28697 · Cited by 348 · see citing works

Lean NAFLD: A Distinct Entity Shaped by Differential Metabolic Adaptation

Chen, F., Esmaili, S., Rogers, G. B., Bugianesi, E., Petta, S., Marchesini, G., Bayoumi, A., Metwally, M., Azardaryany, M. K., Coulter, S., et al. (2019) · Hepatology · doi:10.1002/hep.30908 · Cited by 330 · see citing works

Beneficial effects of lifestyle intervention in non-obese patients with non-alcoholic fatty liver disease

Wong, V. W.-S., Wong, G. L.-H., Chan, R. S.-M., Shu, S. S.-T., Cheung, B. H.-K., Li, L. S., Chim, A. M.-L., Chan, C. K.-M., Leung, J. K.-Y., Chu, W. C.-W., et al. (2018) · Journal of Hepatology · doi:10.1016/j.jhep.2018.08.011 · Cited by 319 · see citing works

Risk for development of severe liver disease in lean patients with nonalcoholic fatty liver disease: A long‐term follow‐up study

Hagström, H., Nasr, P., Ekstedt, M., Hammar, U., Stal, P. I., Hultcrantz, R. W., & Kechagias, S. (2017) · Hepatology Communications · doi:10.1002/hep4.1124 · Cited by 309 · see citing works

AGA Clinical Practice Update: Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Lean Individuals: Expert Review

Long, M. T., Noureddin, M., & Lim, J. K. (2022) · Gastroenterology · doi:10.1053/j.gastro.2022.06.023 · Cited by 299 · see citing works

Adiponectin-leptin Ratio is a Functional Biomarker of Adipose Tissue Inflammation

Frühbeck, G., Catalán, V., Rodrı́guez, A., Ramírez, B., Becerril, S., Salvador, J., Colina, I., & Gómez‐Ambrosi, J. (2019) · Nutrients · doi:10.3390/nu11020454 · Cited by 265 · see citing works

Metabolic (dysfunction)-associated fatty liver disease in individuals of normal weight

Eslam, M., El‐Serag, H. B., Francque, S., Sarin, S. K., Wei, L., Bugianesi, E., & George, J. (2022) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-022-00635-5 · Cited by 246 · see citing works

Effect of Fecal Microbiota Transplantation on Non-Alcoholic Fatty Liver Disease: A Randomized Clinical Trial

Xue, L.-F., Deng, Z., Luo, W.-H., He, X., & Chen, Y. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.759306 · Cited by 242 · see citing works

Clinical and Metabolic Characterization of Lean Caucasian Subjects With Non-alcoholic Fatty Liver

Feldman, A., Eder, S. K., Felder, T. K., Kedenko, L., Paulweber, B., Stadlmayr, A., Huber-Schönauer, U., Niederseer, D., Stickel, F., Auer, S., et al. (2016) · The American Journal of Gastroenterology · doi:10.1038/ajg.2016.318 · Cited by 239 · see citing works

Liver and Cardiovascular Damage in Patients With Lean Nonalcoholic Fatty Liver Disease, and Association With Visceral Obesity

Fracanzani, A. L., Petta, S., Lombardi, R., Pisano, G., Russello, M., Consonni, D., Marco, V. D., Cammà, C., Mensi, L., Dongiovanni, P., et al. (2017) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2017.04.045 · Cited by 230 · see citing works

Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease

Chen, Y., Du, X., Kuppa, A., Feitosa, M. F., Bielak, L. F., O’Connell, J. R., Musani, S. K., Guo, X., Kahali, B., Chen, V. L., et al. (2023) · Nature Genetics · doi:10.1038/s41588-023-01497-6 · Cited by 215 · see citing works

Caucasian lean subjects with non-alcoholic fatty liver disease share long-term prognosis of non-lean: time for reappraisal of BMI-driven approach?

Younes, R., Govaere, O., Petta, S., Miele, L., Tiniakos, D., Burt, A., David, E., Vecchio, F. M., Maggioni, M., Cabibi, D., et al. (2022) · Gut · doi:10.1136/gutjnl-2020-322564 · Cited by 205 · see citing works

A Polygenic Risk Score to Refine Risk Stratification and Prediction for Severe Liver Disease by Clinical Fibrosis Scores

De Vincentis, A., Tavaglione, F., Jamialahmadi, O., Picardi, A., Antonelli Incalzi, R., Valenti, L., Romeo, S., & Vespasiani-Gentilucci, U. (2022) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2021.05.056 · Cited by 158 · see citing works

Prevalence and Profile of Nonalcoholic Fatty Liver Disease in Lean Adults: Systematic Review and Meta‐Analysis

Young, S. K., Tariq, R., Provenza, J., Satapathy, S. K., Faisal, K., Choudhry, A., Friedman, S. L., & Singal, A. K. (2020) · Hepatology Communications · doi:10.1002/hep4.1519 · Cited by 154 · see citing works

Metabolic dysfunction-associated steatotic liver disease (MASLD) definition is better than MAFLD criteria for lean patients with NAFLD

De, A., Bhagat, N., Mehta, M., Taneja, S., & Duseja, A. K. (2023) · Journal of Hepatology · doi:10.1016/j.jhep.2023.07.031 · Cited by 148 · see citing works

379 Characteristics and Long-Term Prognosis of Lean Patients With Nonalcoholic Fatty Liver Disease

Cruz, A. C. D., Bugianesi, E., George, J., Day, C. P., Liaquat, H., Charatcharoenwitthaya, P., Mills, P. R., Dam‐Larsen, S., Bjornsson, E. S., Hafliðadóttir, S., et al. (2014) · Gastroenterology · doi:10.1016/s0016-5085(14)63307-2 · Cited by 144 · see citing works

Gut microbiome composition in lean patients with NASH is associated with liver damage independent of caloric intake: A prospective pilot study

Duarte, S. M. B., Stefano, J. T., Miele, L., Ponziani, F. R., de Souza-Basqueira, M., Okada, L. S. R. R., Costa, F., Toda, K., Mazo, D. F. D. C., Sabino, É. C., et al. (2017) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2017.10.014 · Cited by 136 · see citing works

Non-alcoholic Fatty Liver Disease and Alcohol-Related Liver Disease: Two Intertwined Entities

Idalsoaga, F., Kulkarni, A. V., Mousa, O. Y., Arrese, M., & Arab, J. P. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.00448 · Cited by 136 · see citing works

Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology

Chen, V. L., Du, X., Chen, Y., Kuppa, A., Handelman, S. K., Vohnoutka, R. B., Peyser, P. A., Palmer, N. D., Bielak, L. F., Halligan, B. D., et al. (2021) · Nature Communications · doi:10.1038/s41467-020-20870-1 · Cited by 129 · see citing works

Effect of increased alcohol consumption during COVID‐19 pandemic on alcohol‐associated liver disease: A modeling study

Julien, J., Ayer, T., Tapper, E. B., Barbosa, C., Dowd, W. N., & Chhatwal, J. (2021) · Hepatology · doi:10.1002/hep.32272 · Cited by 129 · see citing works

Nonalcoholic fatty liver disease in Asia: emerging perspectives

Seto, W., & Yuen, M. (2016) · Journal of Gastroenterology · doi:10.1007/s00535-016-1264-3 · Cited by 123 · see citing works

Lean non-alcoholic fatty liver disease

Wang, A. Y., Dhaliwal, J., & Mouzaki, M. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2018.08.008 · Cited by 120 · see citing works

Lean individuals with NAFLD have more severe liver disease and poorer clinical outcomes (NASH-CO Study)

Nabi, O., Lapidus, N., Boursier, J., de Lédinghen, V., Petit, J., Kab, S., Renuy, A., Zins, M., Lacombe, K., & Serfaty, L. (2023) · Hepatology · doi:10.1097/hep.0000000000000329 · Cited by 116 · see citing works

Comparative Burden of Metabolic Dysfunction in Lean NAFLD vs Non-lean NAFLD - A Systematic Review and Meta-analysis

Tang, A. S. P., Ng, C. H., Phang, P. H., Chan, K. E., Chin, Y. H., Fu, C. E., Zeng, R. W., Xiao, J., Tan, D. J. H., Quek, J., et al. (2022) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2022.06.029 · Cited by 106 · see citing works

Incorporating fatty liver disease in multidisciplinary care and novel clinical trial designs for patients with metabolic diseases

Eslam, M., Ahmed, A., Després, J., Jha, V., Halford, J. C. G., Chieh, J. T. W., Harris, D. C. H., Nangaku, M., Colagiuri, S., Targher, G., et al. (2021) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(21)00132-1 · Cited by 101 · see citing works

Natural History of Nonalcoholic Fatty Liver Disease With Normal Body Mass Index: A Population-Based Study

Ahmed, O. T., Gidener, T., Mara, K. C., Larson, J. J., Therneau, T. M., & Allen, A. M. (2021) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2021.07.016 · Cited by 94 · see citing works

Exercise Training Is Associated With Treatment Response in Liver Fat Content by Magnetic Resonance Imaging Independent of Clinically Significant Body Weight Loss in Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis

Stine, J. G., DiJoseph, K., Pattison, Z., Harrington, A., Chinchilli, V. M., Schmitz, K. H., & Loomba, R. (2023) · American Journal of Gastroenterology · doi:10.14309/ajg.0000000000002098 · Cited by 94 · see citing works

Cardiovascular Risk Is Elevated in Lean Subjects with Nonalcoholic Fatty Liver Disease

Kim, Y., Han, E., Lee, J. S., Lee, H. W., Kim, B. K., Kim, M. K., Kim, H. S., Park, J. Y., Kim, D. Y., Ahn, S. H., et al. (2021) · Gut and Liver · doi:10.5009/gnl210084 · Cited by 87 · see citing works

Physical activity and sarcopenia in older adults

Meier, N. F., & Lee, D.-C. (2019) · Aging Clinical and Experimental Research · doi:10.1007/s40520-019-01371-8 · Cited by 86 · see citing works

Systematic review with meta‐analysis: bariatric surgery reduces the incidence of hepatocellular carcinoma

Ramai, D., Singh, J. K., Lester, J., Khan, S. R., Chandan, S., Tartaglia, N., Ambrosi, A., Serviddio, G., & Facciorusso, A. (2021) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.16335 · Cited by 86 · see citing works

Emerging role of genomic analysis in clinical evaluation of lean individuals with NAFLD

Vilarinho, S., Ajmera, V., Zheng, M., & Loomba, R. (2021) · Hepatology · doi:10.1002/hep.32047 · Cited by 85 · see citing works

Consistency between self-reported alcohol consumption and biological markers among patients with alcohol use disorder – A systematic review

Nielsen, D. G., Andersen, K., Nielsen, A. S., Juhl, C. B., & Mellentin, A. I. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.006 · Cited by 84 · see citing works

Lean NAFLD: an underrecognized and challenging disorder in medicine

Maier, S., Wieland, A. C., Cree‐Green, M., Nadeau, K. J., Sullivan, S. A., Lanaspa, M. A., Johnson, R. J., & Jensen, T. (2021) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-020-09621-1 · Cited by 77 · see citing works

Race and Ethnicity in Non-Alcoholic Fatty Liver Disease (NAFLD): A Narrative Review

Riazi, K., Swain, M. G., Congly, S. E., Kaplan, G. G., & Shaheen, A. A. (2022) · Nutrients · doi:10.3390/nu14214556 · Cited by 71 · see citing works

Lean Americans With Nonalcoholic Fatty Liver Disease Have Lower Rates of Cirrhosis and Comorbid Diseases

Weinberg, E. M., Trinh, H. N., Firpi, R. J., Bhamidimarri, K. R., Klein, S., Durlam, J., Watkins, S. E., Reddy, K. R., Weiss, M., Zink, R. C., et al. (2020) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2020.06.066 · Cited by 64 · see citing works

Hepatocellular carcinoma in non-alcoholic fatty liver disease—a review of an emerging challenge facing clinicians

Geh, D., Manas, D., & Reeves, H. L. (2021) · HepatoBiliary Surgery and Nutrition · doi:10.21037/hbsn.2019.08.08 · Cited by 63 · see citing works

Higher mortality among lean patients with non-alcoholic fatty liver disease despite fewer metabolic comorbidities

Wijarnpreecha, K., Li, F., Lundin, S. K., Suresh, D., Song, M. W., Tao, C., Chen, V. L., & Lok, A. S. F. (2023) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.17424 · Cited by 61 · see citing works

Gastrointestinal cancers in lean individuals with non‐alcoholic fatty liver disease: A systematic review and meta‐analysis

de Souza, M. H. G., Diaz, I., Barchetta, I., & Mantovani, A. (2023) · Liver International · doi:10.1111/liv.15763 · Cited by 60 · see citing works

The relationship between glycosylated haemoglobin (HbA1c) and measures of insulin resistance across a range of glucose tolerance

Borai, A., Livingstone, C., Abdelaal, F., Bawazeer, A., Keti, V., & Ferns, G. A. (2011) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365513.2010.547947 · Cited by 55 · see citing works

Inherited non-alcoholic fatty liver disease and dyslipidemia due to monoallelic ABHD5 mutations

Youssefian, L., Vahidnezhad, H., Saeidian, A. H., Pajouhanfar‎, S., Sotoudeh, S., Mansouri, P., Amirkashani, D., Zeinali, S., Levine, M. A., Peris, K., et al. (2019) · Journal of Hepatology · doi:10.1016/j.jhep.2019.03.026 · Cited by 55 · see citing works

Nonalcoholic Fatty Liver Disease in Lean Subjects: Associations With Metabolic Dysregulation and Cardiovascular Risk—A Single-Center Cross-Sectional Study

Semmler, G., Wernly, S., Bachmayer, S., Wernly, B., Schwenoha, L., Huber-Schönauer, U., Stickel, F., Niederseer, D., Aigner, E. S., & Datz, C. (2021) · Clinical and Translational Gastroenterology · doi:10.14309/ctg.0000000000000326 · Cited by 54 · see citing works

Epidemiology and prevalence of lean nonalcoholic fatty liver disease and associated cirrhosis, hepatocellular carcinoma, and cardiovascular outcomes in the United States: a population‐based study and review of literature

Almomani, A., Kumar, P. N., Onwuzo, S., Boustany, A., Krishtopaytis, E., Hitawala, A. A., Alshaikh, D., Albakri, A. A., Hussein, L., Hussein, E., et al. (2022) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.16049 · Cited by 43 · see citing works

Outcomes of subjects who are lean, overweight or obese with nonalcoholic fatty liver disease: A cohort study in China

Lan, Y., Lu, Y., Li, J., Hu, S., Chen, S., Wang, Y., Yuan, X., Liu, H., Wang, X., Wu, S., et al. (2022) · Hepatology Communications · doi:10.1002/hep4.2081 · Cited by 37 · see citing works

From Shadows to Spotlight: Exploring the Escalating Burden of Alcohol-Associated Liver Disease and Alcohol Use Disorder in Young Women

Danpanichkul, P., Ng, C. H., Muthiah, M. D., Suparan, K., Tan, D. J. H., Duangsonk, K., Sukphutanan, B., Kongarin, S., Harinwan, N., Panpradist, N., et al. (2023) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000002642 · Cited by 36 · see citing works

Novel Serum Biomarkers for Detection of Excessive Alcohol Use

Liangpunsakul, S., Lai, X., Ross, R. A., Yu, Z., Modlik, E., Westerhold, C., Heathers, L., Paul, R., O’Connor, S., Crabb, D. W., et al. (2015) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12654 · Cited by 32 · see citing works

The silent burden of non‐alcoholic fatty liver disease in the elderly: A global burden of disease analysis

Danpanichkul, P., Ng, C. H., Muthiah, M. D., Duangsonk, K., Yong, J. N., Tan, D. J. H., Lim, W. H., Wong, Z. Y., Syn, N. L. X., Tsusumi, T., et al. (2023) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.17714 · Cited by 32 · see citing works

Interactions between Metabolic Syndrome, MASLD, and Arterial Stiffening: A Single-Center Cross-Sectional Study

Solomon, A., Negrea, M. O., Cipăian, C. R., Boicean, A., Mihăilă, R. G., Rezi, C., Cristinescu, B. A., Berghea-Neamtu, C. S., Popa, M. L., Teodoru, M., et al. (2023) · Healthcare · doi:10.3390/healthcare11192696 · Cited by 32 · see citing works

Changing trends of liver transplantation and mortality from non-alcoholic fatty liver disease

Majumdar, A., & Tsochatzis, E. A. (2020) · Metabolism · doi:10.1016/j.metabol.2020.154291 · Cited by 31 · see citing works

Presence of sarcopenia identifies a special group of lean NAFLD in middle-aged and older people

Zhu, X., Huang, Q., Ma, S., Chen, L., Wu, Q., Wu, L., Ma, H., Li, X., Li, Q., Aleteng, Q., et al. (2022) · Hepatology International · doi:10.1007/s12072-022-10439-z · Cited by 30 · see citing works

NAFLD in Lean Asians

Eslam, M., Chen, F., & George, J. (2020) · Clinical Liver Disease · doi:10.1002/cld.930 · Cited by 29 · see citing works

Fatty Liver Disease, Metabolism and Alcohol Interplay: A Comprehensive Review

Odriozola, A., Santos‐Laso, Á., Barrio, M. D., Cabezas, J., Iruzubieta, P., Arias, M., Rivas, C., Duque, J. C. R., Antón, Á., Fábrega, E., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24097791 · Cited by 28 · see citing works

The Association of Sarcopenia and Visceral Obesity with Lean Nonalcoholic Fatty Liver Disease in Chinese Patients with Type 2 Diabetes Mellitus

Zhang, X., He, Z., Si, Q., Hu, X., Yang, L., Gu, X., Du, L.-J., Wang, L., Pan, L., Li, Y., et al. (2022) · Journal of Diabetes Research · doi:10.1155/2022/2229139 · Cited by 26 · see citing works

Genomic analysis of lean individuals with NAFLD identifies monogenic disorders in a prospective cohort study

Zheng, M., Huang, D. Q., Konkwo, C., Agrawal, S., Khera, A. V., Loomba, R. S., Vilarinho, S., & Ajmera, V. H. (2023) · JHEP Reports · doi:10.1016/j.jhepr.2023.100692 · Cited by 26 · see citing works

Distinctive clinical and genetic features of lean vs overweight fatty liver disease using the UK Biobank

Chahal, D., Sharma, D., Keshavarzi, S., Arisar, F. A. Q., Patel, K., Xu, W., & Bhat, M. (2022) · Hepatology International · doi:10.1007/s12072-022-10304-z · Cited by 25 · see citing works

Diabetes is the strongest risk factor of hepatic fibrosis in lean patients with non-alcoholic fatty liver disease

Park, H., Yoon, E. L., Cho, S., Jun, D. W., & Nah, E. (2021) · Gut · doi:10.1136/gutjnl-2021-325102 · Cited by 23 · see citing works

Special Population

Duseja, A. K., De, A., & Wong, V. W. (2023) · Clinics in Liver Disease · doi:10.1016/j.cld.2023.01.011 · Cited by 23 · see citing works

Adiponectin–leptin ratio for the early detection of lean non-alcoholic fatty liver disease independent of insulin resistance

Lu, C., Yang, K., Chi, Y., Wu, T.-Y., Chiang, C., Chang, H., Huang, K., & Yang, W. (2023) · Annals of Medicine · doi:10.1080/07853890.2023.2179106 · Cited by 22 · see citing works

Genetic variants in HFE are associated with non-alcoholic fatty liver disease in lean individuals

Sun, Z., Pan, X., Tian, A., Surakka, I. L., Wang, T., Xu, J., He, S., Song, J., Tian, X., Tong, D., et al. (2023) · JHEP Reports · doi:10.1016/j.jhepr.2023.100744 · Cited by 22 · see citing works

NAFLD in lean individuals: not a benign disease

Francque, S., & Wong, V. W. (2021) · Gut · doi:10.1136/gutjnl-2021-324162 · Cited by 21 · see citing works

Lean nonalcoholic fatty liver disease: Age‐dependent differences in pathology, prognosis, and liver‐related events

Kawanaka, M., Nishino, K., Kawada, M., Ishii, K., Tanikawa, T., Katsumata, R., Urata, N., Nakamura, J., Suehiro, M., Haruma, K., et al. (2023) · Hepatology Research · doi:10.1111/hepr.13911 · Cited by 18 · see citing works

Longitudinal association between overweight years, polygenic risk and NAFLD, significant fibrosis and cirrhosis

Ajmera, V. H., Wang, N., Xu, H., Liu, C., & Long, M. T. (2023) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.17452 · Cited by 17 · see citing works

Waist circumference mediates the association between rs1260326 in GCKR gene and the odds of lean NAFLD

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The risk of cardiometabolic disorders in lean non-alcoholic fatty liver disease: A longitudinal study

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Lean MASLD and IBD: Exploring the Intersection of Metabolic Dysfunction and the Gut–Liver Axis

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Lean MASLD and Cardiovascular Disease: A Review

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Oxidative Stress in Liver Metabolic Dysfunction and Diseases, with a Focus on Hepatogenic Diabetes: Effect of Alcohol Consumption

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Longitudinal Clinical Outcomes and Mortality from Steatotic Liver Disease: A Meta-Analysis

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Increased Cardiovascular and Cerebrovascular Events in Patients With Lean vs Non-lean MASLD: A Multicenter Analysis

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Ultrasound-derived visceral adipose tissue as a reliable marker of hepato-metabolic risk in patients with MASLD

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Non-alcoholic fatty liver disease in people with normal body weight

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AMPK Activation and Lipid Homeostasis Regulation in MASLD: Investigating the Hepatoprotective and Anti‐Inflammatory Effects of Meta‐Capridin Medium‐Chain Triglycerides

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Molecular mechanisms and pathogenesis of MASH

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Alcohol-related liver and extrahepatic malignancies: burden of disease and socioeconomic disparities in 2019

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Sub-chronic exposure to crude acetylene results in the development of deleterious cardio metabolic changes in Sprague Dawley rats

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Circulating hepatocyte-derived extracellular particles as potential biomarker of steatohepatitis progression to fibrogenesis: Exploring the impact of smoking

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Contemporary global epidemiology of cirrhosis

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DCNN with Barnacles Mating Optimizer for Performance Analysis of Classification for Liver Disease

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Comment on Rotaru et al. Lean MASLD and IBD: Exploring the Intersection of Metabolic Dysfunction and the Gut–Liver Axis. Life 2025, 15, 288

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A new name for an old problem. Metabolic dysfunction-associated steatotic liver disease - review of literature

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Metabolic dysfunction associated steatotic liver disease in lean patients. Diagnostic and treatment challenges

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Evolving Public Attention to Steatotic Liver Disease: A 20‐Year Analysis (2004–2024)

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Implication of the Androgen Receptor in Muscle–Liver Crosstalk: An Overlooked Mechanistic Link in Lean-MASLD

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Low to moderate alcohol intake is not associated with increased liver stiffness or cardiometabolic risk in MASLD: a cross-sectional analysis from NHANES 2017–2018

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Fuel toxicity-associated spectrum (FTAS): a unifying nomenclature for metabolic disorders

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Clinical pathophysiological and health system implications of the transition from NAFLD to MASLD: a narrative review

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Metabolic dysfunction-associated steatotic liver disease and arterial stiffness by body mass index: the Kailuan Study

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Characteristics and outcomes of lean versus non-lean metabolic dysfunction-associated steatohepatitis liver transplant recipients.

Anouti, A., Danpanichkul, P., Dahshi, H., Rady, E. D., Pandurangi, S., Hassan, S., Aqul, A., Kerr, T. A., Kwon, Y. K., Patel, M. S., et al. (2026) · Annals of Hepatology · doi:10.1016/j.aohep.2026.102456

Metabolic dysfunction associated steatotic liver disease in lean patients. Diagnostic and treatment challenges

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Lean Metabolic-Dysfunction-Associated Steatotic Liver Disease (MASLD): Pathophysiology, Diagnostic Challenges, Clinical Outcomes, and Management

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Lean Metabolic Dysfunction‐Associated Steatotic Liver Disease: A Wolf in Sheep's Clothing

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Metabolic dysfunction-associated steatotic liver disease: Prevalence and progression in lean patients

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Lean metabolic dysfunction-associated steatotic liver disease: Current insights and knowledge gaps

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