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Chemical Composition and in Vitro Antimicrobial and Mutagenic Activities of Seven Lamiaceae Essential Oils
Open accessAbstract
Deeper knowledge of the potentiality of aromatic plants can provide results of economic importance for food and pharmacological industry. The essential oils of seven Lamiaceae species were analyzed by gas chromatography-mass spectrometry and assayed for their antibacterial, antifungal and mutagenic activities. Monoterpenes in the oils ranged between 82.47% (hyssop oil) and 97.48% (thyme oil), being mainly represented by oxygenated compounds. The antibacterial activity was evaluated against six pathogenic and five non-pathogenic bacterial strains. Oregano and thyme oils showed the strongest antibacterial activity against the pathogenic ones. The antifungal activity was evaluated against six fungal strains of agrifood interest: the oils tested exhibited variable degrees of activity. Two Salmonella typhimurium strains were used to assess the possible mutagenic activity. No oil showed mutagenic activity. Data obtained let us hypothesise that the use of essential oils could be a viable and safe way to decrease the utilisation of synthetic food preservatives. Further research is needed to obtain information regarding the practical effectiveness of essential oils to prevent the growth of food borne and spoiling microbes under specific application conditions.
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“EOs contain a wide series of secondary metabolites that can inhibit or slow the growth of bacteria, yeasts and moulds [3,4,5].”
From Effect of essential oils on pathogenic bacteria (2013) · cites this paper as [5]
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“De Martino et al. [5,15] observed that two strains of Bacillus cereus behaved differently when exposed to the same EOs and their singular components.”
From Effect of essential oils on pathogenic bacteria (2013) · cites this paper as [5]
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Cited by
Sorted by citations
Effect of essential oils on pathogenic bacteria
Nazzaro, F., Fratianni, F., De Martino, L., Coppola, R., & De Feo, V. (2013) · Pharmaceuticals · doi:10.3390/ph6121451 · Cited by 2,186
“due to the formation of exopolysaccharides that increase resistance to EOs [5,57].”
BackgroundEssential Oils and Antifungal Activity
Nazzaro, F., Fratianni, F., Coppola, R., & Feo, V. D. (2017) · Pharmaceuticals · doi:10.3390/ph10040086 · Cited by 889
Essential Oils as Antimicrobial Agents—Myth or Real Alternative?
Wińska, K., Mączka, W., Łyczko, J., Grabarczyk, M., Czubaszek, A., & Szumny, A. (2019) · Molecules · doi:10.3390/molecules24112130 · Cited by 591
Essential Oils: Chemistry and Pharmacological Activities
de Sousa, D. P., Damasceno, R. O. S., Amorati, R., Elshabrawy, H. A., de Castro, R. D., Bezerra, D. P., Nunes, V. R. V., Gomes, R. C., & Lima, T. C. (2023) · Biomolecules · doi:10.3390/biom13071144 · Cited by 554
Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review
Urîtu, C. M., Mihai, C. T., Stanciu, G. D., Dodi, G., Alexa‐Stratulat, T., Luca, A., Leon, M. M., Ştefănescu, R., Bild, V., Melnic, S., et al. (2018) · Pain Research and Management · doi:10.1155/2018/7801543 · Cited by 398
Metadata
- Authors
- De Martino, L., De Feo, V., & Nazzaro, F.
- Affiliations
- Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, via Ponte don Melillo, 84084 Fisciano (Salerno), Italy
- University of Salerno (IT)
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2009-10-20
- Volume
- 14
- Issue
- 10
- Pages
- 4213-4230
- ISSN
- 1420-3049 (ISSN-L)
- PMC
- PMC6254799
- OpenAlex
- W2055798838
- Cited by
- 169
- References
- 46
- Citations by year
- 2026: 2 · 2025: 10 · 2024: 7 · 2023: 18 · 2022: 11 · 2021: 19 · 2020: 13 · 2019: 14 · 2018: 14 · 2017: 16 · 2016: 6 · 2015: 8 · 2014: 7 · 2013: 10 · 2012: 5
- FWCI
- 7.41
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Molecules (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Insect Pest Control Strategies
- Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
- Keywords
- Lamiaceae, essential oils, chemical composition, antibacterial activity, antifungal activity, mutagenicity, monoterpenes, oregano essential oil, thyme essential oil, Salmonella typhimurium, food preservatives, foodborne pathogens, spoilage microorganisms
- MeSH terms
- Anti-Infective Agents, Bacteria, Fungi, Gas Chromatography-Mass Spectrometry, Mutagens, Oils, Volatile, Lamiaceae
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