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Cited by 289

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Application of Porphyrins in Antibacterial Photodynamic Therapy

Open access
Amos-Tautua, Bamidele, Songca, Sandile, Oluwafemi, Oluwatobi·2019·Molecules

Abstract

Antibiotics are commonly used to control, treat, or prevent bacterial infections, however bacterial resistance to all known classes of traditional antibiotics has greatly increased in the past years especially in hospitals rendering certain therapies ineffective. To limit this emerging public health problem, there is a need to develop non-incursive, non-toxic, and new antimicrobial techniques that act more effectively and quicker than the current antibiotics. One of these effective techniques is antibacterial photodynamic therapy (aPDT). This review focuses on the application of porphyrins in the photo-inactivation of bacteria. Mechanisms of bacterial resistance and some of the current ‘greener’ methods of synthesis of meso-phenyl porphyrins are discussed. In addition, significance and limitations of aPDT are also discussed. Furthermore, we also elaborate on the current clinical applications and the future perspectives and directions of this non-antibiotic therapeutic strategy in combating infectious diseases.

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Crossref · 10.3390/molecules24132456

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Metadata

Authors
Amos-Tautua, B., Songca, S., & Oluwafemi, O.
Venue
Molecules
Publisher
MDPI AG
Published
2019-07-04
Volume
24
Issue
13
Pages
2456
ISSN
1420-3049 (ISSN-L)
OpenAlex
W2954110626
Cited by
289
References
5
FWCI
22.40
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Application of Porphyrins in Antibacterial Photodynamic Therapy. https://app.cochat.ai/papers/10.3390/molecules24132456
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Amos-Tautua, B., Songca, S., & Oluwafemi, O. (2019). Application of Porphyrins in Antibacterial Photodynamic Therapy. Molecules. https://doi.org/10.3390/molecules24132456

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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