The DOI matches its Crossref record; 103 of the 103 references it cites were found in a registry or an index.
The Effects of Flavonoids in Cardiovascular Diseases
Open accessAbstract
Flavonoids are metabolites of plants and fungus. Flavonoid research has been paid special attention to in recent times after the observation of their beneficial effects on the cardiovascular system. These favorable effects are exerted by flavonoids mainly due to their antioxidant properties, which result from the ability to decrease the oxidation of low-density lipoproteins, thus improving the lipid profiles. The other positive effect exerted on the cardiovascular system is the ability of flavonoids to produce vasodilation and regulate the apoptotic processes in the endothelium. Researchers suggested that these effects, including their anti-inflammatory function, are consequences of flavonoids’ potent antioxidant properties, but recent studies have shown multiple signaling pathways linked to them, thus suggesting that there are more mechanisms involved in the beneficial effect of the flavonoids on the human body. This review aims to present the latest data on the classification of these substances, their main mechanisms of action in the human body, and the beneficial effects on the physiological and pathological status of the cardiovascular system.
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Cites
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Cited by
Plant Flavonoids: Chemical Characteristics and Biological Activity
Dias, M. C., Pinto, D. C. G. A., & Silva, A. M. S. (2021) · Molecules · doi:10.3390/molecules26175377 · Cited by 1,512
Almuntashiri, S. A., Alsubaie, F. F., & Alotaybi, M. (2025) · Cureus · doi:10.7759/cureus.78629 · Cited by 10
“These compounds, such as flavonoids and carotenoids, have been linked to reduced risk of cardiovascular diseases and certain cancers [43,56].”
Metadata
- Authors
- Ciumărnean, L., Milaciu, M. V., Runcan, O., Vesa, Ș. C., Răchișan, A. L., Negrean, V., Perné, M.-G., Donca, V. I., Alexescu, T.-G., Para, I., & Dogaru, G.
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2020-09-21
- Volume
- 25
- Issue
- 18
- Pages
- 4320
- ISSN
- 1420-3049 (ISSN-L)
- OpenAlex
- W3087634314
- Cited by
- 444
- References
- 103
- FWCI
- 19.61
- Type
- journal article
- Language
- en
- Open access
- gold
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- Ciumărnean, L., Milaciu, M. V., Runcan, O., Vesa, Ș. C., Răchișan, A. L., Negrean, V., Perné, M.-G., Donca, V. I., Alexescu, T.-G., Para, I., & Dogaru, G. (2020). The Effects of Flavonoids in Cardiovascular Diseases. Molecules. https://doi.org/10.3390/molecules25184320
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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