Cited by 346Nutritional Studies and DietDietary Effects on HealthDiabetes Treatment and Management

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Mediterranean Diet Effects on Type 2 Diabetes Prevention, Disease Progression, and Related Mechanisms. A Review

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Martín-Peláez, Sandra, Fito, Montse, Castaner, Olga·2020·Nutrients

DOI 10.3390/nu12082236PMC PMC7468821

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Abstract

The search for a quality diet has grown over the past decade. Diet is considered one of the pillars for the prevention and progression of several diseases, among them: diabetes. Type 2 diabetes (T2D) is an epidemic of western countries that increases the vulnerability of other diseases, such as cardiovascular and cancer. T2D is associated with lifestyle and diet. The traditional Mediterranean diet has proven its benefits over several cardiovascular risk factors, and specifically on diabetes. This review compiles recent published evidence on the effects of the Mediterranean diet on the incidence and progression of type 2 diabetes (T2D) and its relation with several other cardiovascular healthy diets. We will also focus on how the Mediterranean diet could play a role in T2D-related mechanisms, such as anti-inflammatory or antioxidant compounds, glucagon-like peptide agonist compounds, and changes in gut microbiota. Each component of the Mediterranean diet could be involved in processes related to diabetes homeostasis, many of them sharing common physio-pathological pathways. The importance of this diet within the set of habits of a healthy lifestyle must be emphasized.

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Authors: Martín-Peláez, S., Fito, M., & Castaner, O.
Affiliations: Department of Preventive Medicine and Public Health, Faculty of Medicine, University of Granada, 18071 Granada, Spain
Cardiovascular Risk and Nutrition Research Group, Hospital del Mar Medical Research Institute [IMIM], 08003 Barcelona, Spain
ORCID: Martín-Peláez, Sandra
Castaner, Olga
Venue: Nutrients
Publisher: MDPI AG
Published: 2020-07-27
Volume: 12
Issue: 8
Pages: 2236
ISSN: 2072-6643 (ISSN-L)
DOI: 10.3390/nu12082236
PMC: PMC7468821
OpenAlex: W3044725267
Cited by: 330
References: 109
Citations by year: 2026: 48 · 2025: 64 · 2024: 66 · 2023: 67 · 2022: 59 · 2021: 26
FWCI: 6.35
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Nutrients (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, cc-by)
RISalud Institutional Health Repository of Andalucía (submittedVersion, cc-by)
Institutional Repository of the University of Granada (University of Granada) (submittedVersion, cc-by)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Repositori digital de la UPF (Universitat Pompeu Fabra) (submittedVersion, cc-by)
Funders: Instituto de Salud Carlos III (PI18/00020, JR17/00022)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Keywords: Mediterranean diet, type 2 diabetes, diabetes prevention, disease progression, anti-inflammatory agents, antioxidants, gut microbiota, cardiovascular risk factors, healthy lifestyle, diabetes pathophysiology
MeSH terms: Diet, Healthy, Heart Disease Risk Factors, Adult, Cardiovascular Diseases, Diabetes Mellitus, Type 2, Female, Humans, Male, Middle Aged, Incidence, Disease Progression, Diet, Mediterranean

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Mediterranean Diet Effects on Type 2 Diabetes Prevention, Disease Progression, and Related Mechanisms. A Review

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