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Cited by 16Diet and metabolism studiesDietary Effects on HealthMuscle metabolism and nutrition

High-Protein or Low Glycemic Index Diet—Which Energy-Restricted Diet Is Better to Start a Weight Loss Program?

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Waliłko, Ewa, Napierała, Małgorzata, Bryśkiewicz, Marta, Fronczyk, Aneta, Majkowska, Liliana·2021·Nutrients
DOI 10.3390/nu13041086PMC PMC8066419
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Abstract

Background: To date, no crossover studies have compared the effects of high-protein (HP) and low glycemic index (LGI) diets applied as starting energy-restricted diets. Methods: Thirty-five overweight or obese volunteers with sedentary lifestyles aged 41.4 ± 11.0 years, with body mass index (BMI) of 33.6 ± 4.2 kg/m2, without diabetes, completed an 8-week randomized crossover study of an energy-restricted diet (reduction of 30%; approximately 600 kcal/day). The anthropometric parameters, body composition, 24 h blood pressure, and basic metabolic profile were measured at baseline and after completing the two 4-week diets; i.e., the HP (protein at 30% of the daily energy intake) or LGI diet, followed by the opposite diet. All subjects maintained food diaries and attended six counselling sessions with a clinical dietitian. Results: The final weight loss was not significantly different when the HP diet was used first but was associated with a greater loss of fat mass: 4.6 kg (5.8; 3.0 kg) vs. 2.2 (4.5; 0.8); p < 0.025, preserved muscle mass, and reduced LDL-cholesterol. Conclusions: A short-term HP diet applied as a jump-start diet appeared to be more beneficial than an LGI diet, as indicated by the greater fat mass loss, preservation of muscle mass, and better effects on the lipid profile.

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  • Environmental factors such as availability of high-calorie foods and sedentary lifestyles may present challenges to maintaining a healthy weight.

    “Environmental factors, such as the availability of high-calorie foods and sedentary lifestyles, may also present challenges to maintaining a healthy weight [101].”

    From Comparing caloric restriction regimens for effective weight management in adults: a systematic review and network meta-analysis (2024) · cites this paper as [101]

    The Introduction discusses calorie restriction and diet composition, while Methods §2.1 describes participants as having sedentary lifestyles. Neither passage says that the availability of high-calorie foods or sedentary lifestyles presents a challenge to maintaining a healthy weight. Searches for food availability, environmental factors, and sedentary lifestyles found no passage making that point. (LLM, conf=0.70)

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Cited by

Sorted by citations

Authors
Waliłko, E., Napierała, M., Bryśkiewicz, M., Fronczyk, A., & Majkowska, L.
Affiliations
Pomeranian Medical University (PL)
Corresponding author
Majkowska, Liliana
ORCID
Venue
Nutrients
Publisher
MDPI AG
Published
2021-03-26
Volume
13
Issue
4
Pages
1086
ISSN
2072-6643 (ISSN-L)
DOI
10.3390/nu13041086
PMC
PMC8066419
OpenAlex
W3145322769
Cited by
16
References
8
Citations by year
2026: 2 · 2025: 3 · 2024: 5 · 2023: 2 · 2022: 2 · 2021: 2
FWCI
1.73
Type
journal article
Language
en
Open access
Licence
Locations
  • Nutrients (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Physiology › Diet and metabolism studies
  • Health Sciences › Medicine › Physiology › Dietary Effects on Health
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
Keywords
high-protein diet, low glycemic index diet, hypocaloric diet, weight loss, fat loss, muscle mass preservation, LDL cholesterol, lipid profile, overweight and obesity, sedentary lifestyle, dietary intervention
MeSH terms
Diet, High-Protein, Adult, Body Composition, Diet, Reducing, Humans, Middle Aged, Weight Loss, Cross-Over Studies, Caloric Restriction, Glycemic Index, Overweight

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