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Phenotypes and Endotypes of Peach Allergy: What Is New?

Barni, Simona, Caimmi, Davide, Chiera, Fernanda, Comberiati, Pasquale, Mastrorilli, Carla, Pelosi, Umberto, Paravati, Francesco, Marseglia, Gian Luigi, Arasi, Stefania·2022·Nutrients
DOI 10.3390/nu14050998PMC PMC8912752
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Abstract

Peach allergy is emerging as a common type of fresh-fruit allergy in Europe, especially in the Mediterranean area. The clinical manifestations of peach allergy tend to have a peculiar geographical distribution and can range from mild oral symptoms to anaphylaxis, depending on the allergic sensitization profile. The peach allergen Pru p 7, also known as peamaclein, has recently been identified as a marker of peach allergy severity and as being responsible for peculiar clinical features in areas with high exposure to cypress pollen. This review addresses the latest findings on molecular allergens for the diagnosis of peach allergy, the clinical phenotypes and endotypes of peach allergy in adults and children, and management strategies, including immunotherapy, for peach allergy.

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Figure 1 Diagnostic algorithm for peach allergy. Adapted from [40].
Figure 1 Diagnostic algorithm for peach allergy. Adapted from [40].CC BY · PubMed Central

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Cited by

Sorted by citations

Metadata

Authors
Barni, S., Caimmi, D., Chiera, F., Comberiati, P., Mastrorilli, C., Pelosi, U., Paravati, F., Marseglia, G. L., & Arasi, S.
Venue
Nutrients
Publisher
MDPI AG
Published
2022-02-26
Volume
14
Issue
5
Pages
998
ISSN
2072-6643
DOI
10.3390/nu14050998
PMC
PMC8912752
Cited by
22
References
1
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (vor)
Funders
The Italian Society of Pediatric Allergy and Immunology (SIAIP) (0000)

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