Lacticaseibacillus rhamnosus FM9 and Limosilactobacillus fermentum Y57 are as effective as statins at improving blood lipid profile in high cholesterol, high-fat diet model in male Wistar rats
Open accessAbstract
Elevated serum cholesterol is a major risk factor for coronary heart diseases. Some Lactobacillus strains with cholesterol-lowering potential have been isolated from artisanal food products. The purpose of this study was to isolate probiotic Lactobacillus strains from traditional yoghurt (dahi) and yogurt milk (lassi) and investigate the impact of these strains on the blood lipid profile and anti-obesity effect in a high cholesterol high fat diet model in Wistar rats. Eight candidate probiotic strains were chosen based on in vitro probiotic features and cholesterol reduction ability. By 16S rDNA sequencing, these strains were identified as Limosilactibacillus fermentum FM6, L. fermentum FM16, L. fermentum FM12, Lacticaseibacillus rhamnosus FM9, L. fermentum Y55, L. fermentum Y57, L. rhamnosus Y59, and L. fermentum Y63. The safety of these strains was investigated by feeding 2 × 108 CFU/mL in saline water for 28 days in a Wistar rat model. No bacterial translocation or any other adverse effects were observed in animals after administration of strains in water, which indicates the safety of strains. The cholesterol-lowering profile of these probiotics was evaluated in male Wistar rats using a high-fat, high-cholesterol diet (HFCD) model. For 30 days, animals were fed probiotic strains in water with 2 × 108 CFU/mL/rat/day, in addition to a high fat, high cholesterol diet. The cholesterol-lowering effects of various probiotic strains were compared to those of statin. All strains showed improvement in total cholesterol, LDL, HDL, triglycerides, and weight gain. Serum cholesterol levels were reduced by 9% and 8% for L. rhamnosus FM9 and L. fermentum Y57, respectively, compared to 5% for the statin-treated group. HDL levels significantly improved by 46 and 44% for L. rhamnosus FM9 and L. fermentum Y57, respectively, compared to 46% for the statin-treated group. Compared to the statin-treated group, FM9 and Y57 significantly reduced LDL levels by almost twofold. These findings show that these strains can improve blood lipid profiles as effectively as statins in male Wistar rats. Furthermore, probiotic-fed groups helped weight control in animals on HFCD, indicating the possible anti-obesity potential of these strains. These strains can be used to develop food products and supplements to treat ischemic heart diseases and weight management. Clinical trials, however, are required to validate these findings.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Some probiotics are effective in reducing lipid concentrations and lipid deposition in rats fed with a high-fat diet.
“Interestingly, some probiotics are effective in reducing lipid concentrations and lipid deposition in rats fed with a high-fat diet.”
From Lactiplantibacillus plantarum N4 ameliorates lipid metabolism and gut microbiota structure in high fat diet-fed rats (2024) · cites this paper as Zafar et al., 2022
Previous studies have confirmed the efficacy of reducing lipids in rats fed high-fat diets using L. rhamnosus and L. fermentans.
“Previous studies have confirmed the efficacy of reducing lipids in rats fed high-fat diets using L. rhamnosus and L. fermentans (Yadav et al., 2018; Thakkar et al., 2020; Zafar et al., 2022).”
From Lactiplantibacillus plantarum N4 ameliorates lipid metabolism and gut microbiota structure in high fat diet-fed rats (2024) · cites this paper as Zafar et al., 2022
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Zheng, J., Wittouck, S., Salvetti, E., Franz, C. M. A. P., Harris, H. M. B., Mattarelli, P., O’Toole, P. W., Pot, B., Vandamme, P., Walter, J., et al. (2020) · International Journal of Systematic and Evolutionary Microbiology · doi:10.1099/ijsem.0.004107 · Cited by 3,313 · see citing works
Lactic acid bacteria as functional starter cultures for the food fermentation industry
Leroy, F., & De Vuyst, L. (2004) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2003.09.004 · Cited by 1,852 · see citing works
Determination of cholesterol using o-phthalaldehyde
Rudel, L. L., & Morris, M. D. (1973) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)36896-6 · Cited by 1,044 · see citing works
European Society of Cardiology: Cardiovascular Disease Statistics 2017
Timmis, A., Petersen, S. E., Belle, E. V., Townsend, N. P., Conrad, N., Kaplon-Cieslicka, A., Kazakiewicz, D., Kavousi, M., Cvijić, M., Ignatiuk, B., et al. (2017) · European Heart Journal · doi:10.1093/eurheartj/ehag345 · Cited by 964 · see citing works
Cholesterol-Lowering Effects of Probiotics and Prebiotics: A Review of in Vivo and in Vitro Findings
Ooi, L.-G., & Liong, M. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11062499 · Cited by 690 · see citing works
Grefhorst, A., Elzinga, B. M., Voshol, P. J., Plösch, T., Kok, T., Bloks, V. W., van der Sluijs, F. H., Havekes, L. M., Romijn, J. A., Verkade, H. J., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204887200 · Cited by 502 · see citing works
Cholesterol-Lowering Probiotics as Potential Biotherapeutics for Metabolic Diseases
Kumar, M., Nagpal, R., Kumar, R., Hemalatha, R., Verma, V., Kumar, A., Chakraborty, C., Singh, B., Marotta, F., Jain, S., et al. (2012) · Experimental Diabetes Research · doi:10.1155/2012/902917 · Cited by 439 · see citing works
Bao, Y., Zhang, Y., Zhang, Y., Liu, Y., Wang, S., Dong, X., Wang, Y., & Zhang, H. (2009) · Food Control · doi:10.1016/j.foodcont.2009.10.010 · Cited by 395 · see citing works
Probiotic Properties of Lactobacillus plantarum RYPR1 from an Indigenous Fermented Beverage Raabadi
Yadav, R., Puniya, A. K., & Shukla, P. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01683 · Cited by 233 · see citing works
Yoo, S., Kim, Y., Park, D., Jung, U., Jeon, S., Ahn, Y., Huh, C., McGregor, R., & Choi, M. S. (2013) · Obesity · doi:10.1002/oby.20428 · Cited by 230 · see citing works
Xie, N., Cui, Y., Yin, Y.-N., Zhao, X., Yang, J.-W., Wang, Z.-G., Fu, N., Tang, Y., Wang, X.-H., Liu, X.-W., et al. (2011) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-11-53 · Cited by 211 · see citing works
Wang, Y., Xu, N., Xi, A., Ahmed, Z., Zhang, B., & Bai, X. (2009) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-009-2012-x · Cited by 200 · see citing works
Mathara, J. M., Schillinger, U., Guigas, C., Franz, C. M. A. P., Kutima, P. M., Mbugua, S. K., Shin, H. C., & Holzapfel, W. H. (2008) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2008.04.027 · Cited by 189 · see citing works
Kotzamanidis, C., Kourelis, A., LITOPOULOU‐TZANETAKI, E., Tzanetakis, N., & Yiangou, M. (2010) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.04.004 · Cited by 173 · see citing works
Safety Aspects of Genetically Modified Lactic Acid Bacteria
Plavec, T. V., & Berlec, A. (2020) · Microorganisms · doi:10.3390/microorganisms8020297 · Cited by 162 · see citing works
Cholesterol Assimilation byLactobacillusProbiotic Bacteria: AnIn VitroInvestigation
Tomaro-Duchesneau, C., Jones, M. L., Shah, D., Jain, P., Saha, S., & Prakash, S. (2014) · BioMed Research International · doi:10.1155/2014/380316 · Cited by 152 · see citing works
Choi, E. A., & Chang, H. C. (2015) · LWT · doi:10.1016/j.lwt.2015.01.019 · Cited by 149 · see citing works
Pan, D. D., Zeng, X. Q., & Yan, Y. T. (2010) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.4214 · Cited by 143 · see citing works
Ghosh, T., Beniwal, A., Semwal, A., & Navani, N. K. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00502 · Cited by 141 · see citing works
Zarrati, M., Salehi, E., Nourijelyani, K., Mofid, V., Zadeh, M. J. H., Najafi, F., Ghaflati, Z., Bidad, K., Chamari, M., Karimi, M., et al. (2014) · Journal of the American College of Nutrition · doi:10.1080/07315724.2013.874937 · Cited by 130 · see citing works
Probiotic Properties of Exopolysaccharide-Producing Lactobacillus Strains Isolated from Tempoyak
Khalil, E. S., Manap, M. Y. A., Mustafa, S., Alhelli, A. M., & Shokryazdan, P. (2018) · Molecules · doi:10.3390/molecules23020398 · Cited by 128 · see citing works
Antibiotic Resistance of Lactobacillus sp. Isolated from Commercial Probiotic Preparations
Sharma, P., Tomar, S. K., Sangwan, V., Goswami, P., & Singh, R. (2015) · Journal of Food Safety · doi:10.1111/jfs.12211 · Cited by 127 · see citing works
Kumar, R., Grover, S., & Batish, V. K. (2012) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-012-9101-3 · Cited by 123 · see citing works
Mechanisms responsible for the hypocholesterolaemic effect of regular consumption of probiotics
dos Reis, S. A., da Conceição, L. L., Rosa, D. D., Siqueira, N. P., & Pelúzio, M. D. C. G. (2016) · Nutrition Research Reviews · doi:10.1017/s0954422416000226 · Cited by 114 · see citing works
Gao, M., Jebb, S. A., Aveyard, P. N., Ambrosini, G. L., Perez‐Cornago, A., Carter, J. L., Sun, X., & Piernas, C. (2021) · BMC Medicine · doi:10.1186/s12916-021-01958-x · Cited by 109 · see citing works
Liong, M. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2007.tb00309.x · Cited by 106 · see citing works
Turchi, B., Mancini, S., Fratini, F., Pedonese, F., Nuvoloni, R., Bertelloni, F., Ebani, V. V., & Cerri, D. (2013) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-013-1356-7 · Cited by 90 · see citing works
de Champs, C., Maroncle, N., Balestrino, D., Rich, C., & Forestier, C. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.3.1270-1273.2003 · Cited by 86 · see citing works
Probiotic characteristics of Lactobacillus fermentum strains isolated from tulum cheese
Tulumoğlu, Ş., Kaya, H. İ., & Şimşek, Ö. (2014) · Anaerobe · doi:10.1016/j.anaerobe.2014.09.015 · Cited by 85 · see citing works
Harun‐ur‐Rashid, M., Togo, K., Ueda, M., & MIYAMOTO, T. (2006) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-006-9201-x · Cited by 72 · see citing works
Cavallini, D., Suzuki, J. Y., Abdalla, D. S. P., Vendramini, R. C., Pauly-Silveira, N. D., Roselino, M. N., Pinto, R. A., & Rossi, E. A. (2011) · Lipids in Health and Disease · doi:10.1186/1476-511x-10-126 · Cited by 66 · see citing works
Intervention of five strains of Lactobacillus on obesity in mice induced by high-fat diet
Wang, M., Zhang, B., Hu, J., Nie, S., Xiong, T., & Xie, M. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104078 · Cited by 66 · see citing works
Lara‐Villoslada, F., Sierra, S., Martı́n, R., Delgado, S., Rodríguez, J. M., Olivares, M. M., & Xaus, J. (2006) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2006.03225.x · Cited by 54 · see citing works
Liang, C., Zhou, X., Jiao, Y., Guo, M., Li, M., Gong, P., Lyu, L., Niu, H., Wu, Y., Chen, S., et al. (2021) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202100136 · Cited by 44 · see citing works
Two different methods for screening of bile salt hydrolase activity in Lactobacillus strains
Sedláčková, P., Horáčková, Š., Shi, T., Kosová, M., & Plocková, M. (2015) · Czech Journal of Food Sciences · doi:10.17221/299/2014-cjfs · Cited by 42 · see citing works
Bao, Q., Yu, J. Z., Liu, W., Qing, M., Wang, W., Chen, X., Wang, F., Li, M., Wang, H., Lv, Q., et al. (2012) · Dairy Science and Technology · doi:10.1007/s13594-012-0061-x · Cited by 40 · see citing works
Le, B., & Yang, S. H. (2018) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-018-9469-9 · Cited by 39 · see citing works
Guo, L., Wang, L., Liu, F., Li, B., Tang, Y., Yu, S., Zhang, D., & Huo, G. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103497 · Cited by 37 · see citing works
Detection and Purification of Bacillus cereus Enterotoxins
Lindbäck, T., & Granum, P. E. (2008) · Methods in biotechnology · doi:10.1385/1-59259-990-7:015 · Cited by 32 · see citing works
Thakkar, P. N., Patel, A., Modi, H. A., & Prajapati, J. B. (2020) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-019-09622-w · Cited by 32 · see citing works
Russo, M., Marquez, A., Herrera, H., Mukdsi, M. C. A., Saavedra, L., Hebert, E. M., Gauffin-Cano, P., & Medina, R. B. (2020) · Food & Function · doi:10.1039/d0fo00730g · Cited by 29 · see citing works
Park, J. H., Lee, Y. H., Moon, E., Seok, S. H., Bæk, M., Lee, H., Kim, D. J., & Kim, C. H. (2005) · Seoul National University Open Repository (Seoul National University) · Cited by 25 · see citing works
Peng, Z., Wei, B., Huang, T., Liu, Z., Guan, Q., Xie, M., Li, H., & Xiong, T. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.566473 · Cited by 15 · see citing works
Koirala, R., Ricci, G., Taverniti, V., Ferrario, C., Malla, R., Shrestha, S., Fortina, M. G., & Guglielmetti, S. (2014) · Dairy Science and Technology · doi:10.1007/s13594-014-0167-4 · Cited by 13 · see citing works
Physicians’ Experiences as Patients with Statin Side Effects: A Case Series
Koslik, H. J., Meskimen, A. H., & Golomb, B. A. (2017) · Drug Safety - Case Reports · doi:10.1007/s40800-017-0045-0 · Cited by 13 · see citing works
Bonczar, G., Walczycka, M. B., Domagała, J., Maciejowski, K., Najgebauer‐Lejko, D., Sady, M., & Wszołek, M. (2015) · Small Ruminant Research · doi:10.1016/j.smallrumres.2015.12.033 · Cited by 10 · see citing works
Safety concerns of Probiotic use: A review
Suresh, K. S. (2013) · IOSR Journal of Dental and Medical Sciences · doi:10.9790/0853-1215660 · Cited by 6 · see citing works
Flagged first, then by citations
3 of the 51 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Agolino, G., Pino, A., Vaccalluzzo, A., Cristofolini, M., Solieri, L., Caggia, C., & Randazzo, C. L. (2024) · Journal of Functional Foods · doi:10.1016/j.jff.2024.106357 · Cited by 87 · see citing works
Exploring lactic acid bacteria in food, human health, and agriculture
Murata, R., Shim, Y. Y., Kim, Y. J., Reaney, M. J. T., & Tse, T. J. (2025) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2025.2493236 · Cited by 42 · see citing works
Freire, M. O. D. L., Neto, J. P. R. C., Lemos, D. E. D. A., de Albuquerque, T. M. R., Garcia, E. F., de Souza, E. L., & Alves, J. L. D. B. (2024) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-024-10235-1 · Cited by 35 · see citing works
Gut Microbiota and Coronary Artery Disease: Current Therapeutic Perspectives
Katsimichas, T., Theofilis, P., Tsioufis, K. P., & Tousoulis, D. (2023) · Metabolites · doi:10.3390/metabo13020256 · Cited by 31 · see citing works
Liu, M., Uyanga, V. A., Cao, X., Liu, X., & Lin, H. (2023) · The Journal of Poultry Science · doi:10.2141/jpsa.2023011 · Cited by 24 · see citing works
Jo, D.-M., Ko, S.-C., Kim, K. W., Yang, D., Kim, J.-Y., Oh, G.-W., Choi, G., Lee, D.-S., Tabassum, N., Kim, Y.-M., et al. (2025) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2025.105309 · Cited by 20 · see citing works
Agolino, G., Cristofolini, M., Vaccalluzzo, A., Tagliazucchi, D., Cattivelli, A., Pino, A., Caggia, C., Solieri, L., & Randazzo, C. L. (2025) · Biomolecules · doi:10.3390/biom15010086 · Cited by 19 · see citing works
Asai, T. T., Yoshikawa, S., Ikeda, Y., Taniguchi, K., Sawamura, H., Tsuji, A., & Matsuda, S. (2022) · Biomolecules · doi:10.3390/biom13010010 · Cited by 19 · see citing works
Kowalski, K., Żebrowska-Różańska, P., Karpiński, P., Kujawa, D., Łaczmański, Ł., Samochowiec, J., Chęć, M., Piotrowski, P., & Misiak, B. (2023) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2023.110834 · Cited by 16 · see citing works
Deng, M., Zhang, S., Wu, S., Jiang, Q., Teng, W., Luo, T., Ouyang, Y., Liu, J., & Gu, B. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1390293 · Cited by 15 · see citing works
Jeong, H., Hwang, U.-S., Choi, H.-J., & Park, Y. (2023) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-023-10198-9 · Cited by 15 · see citing works
Unveiling the Impact of Lactic Acid Bacteria on Blood Lipid Regulation for Cardiovascular Health
Yılmaz, B., Arslan, N., Şahin, T. Ö., Ağagündüz, D., Özoğul, F., & Rocha, J. M. (2024) · Fermentation · doi:10.3390/fermentation10070350 · Cited by 15 · see citing works
An Overview of the Use and Applications of Limosilactobacillus fermentum in Broiler Chickens
Racines, M. P., Solis, M. N., Šefcová, M. A., Herich, R., Larrea-Álvarez, M., & Révajová, V. (2023) · Microorganisms · doi:10.3390/microorganisms11081944 · Cited by 14 · see citing works
Melo, N. C. D. O., Cuevas‐Sierra, A., Arellano-García, L., Portillo, M. P., Milton‐Laskibar, I., & Martínez, J. A. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105808 · Cited by 12 · see citing works
Ma, C., Chen, X., Zheng, M., Zhang, S., Liu, Q., Lyu, J., Pang, X., & Wang, Y. (2024) · Foods · doi:10.3390/foods13244058 · Cited by 12 · see citing works
Melia, S., Juliyarsi, I., Kurnia, Y. F., Aritonang, S. N., Purwati, E., Sukma, A., Fitria, N., Susmiati, S., Meinapuri, M., Pratama, Y. E., et al. (2023) · Journal of Advanced Veterinary and Animal Research · doi:10.5455/javar.2023.j653 · Cited by 11 · see citing works
Lactobacillus rhamnosus B16 regulates lipid metabolism homeostasis by producing acetic acid
Che, Z., Huang, J., Wen, S., Chai, X., Zhang, S., Yu, H., Lin, B., Liang, Y., Ye, Z., & Zeng, J. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-07228-1 · Cited by 9 · see citing works
Unlocking Cardioprotective Potential of Gut Microbiome: Exploring Therapeutic Strategies
Qu, J., Meng, F., Wang, Z., & Xu, W. (2024) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2405.05019 · Cited by 10 · see citing works
Porphyromonas gingivalis induces cardiovascular dysfunction
Stanišić, D., Jeremic, N. S., Singh, M., Pushpakumar, S. B., Mokshagundam, S. P., & Tyagi, S. C. (2023) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2022-0392 · Cited by 8 · see citing works
Guo, H., Singhania, R. R., Patel, A. K., Tsai, T.-R., Tsai, M., Sharma, V., & Dong, C. (2023) · Journal of Food Science and Technology · doi:10.1007/s13197-023-05897-8 · Cited by 8 · see citing works
Sidorova, Y. S., Petrov, N. A., Markova, Y. M., Kolobanov, A. I., & Zorin, S. N. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105383 · Cited by 4 · see citing works
Zepeda-Hernández, A., la Cruz, M. F. R.-D., Antunes‐Ricardo, M., Ortega‐Hernández, É., García-García, J. D., García-Amezquita, L. E., & García‐Cayuela, T. (2025) · International Dairy Journal · doi:10.1016/j.idairyj.2025.106276 · Cited by 4 · see citing works
Ai, X. Z., Zhang, Q., Ma, Q., Fang, M., Zhu, K., Cai, Y., Qinqin, Y. A. N. G., & ZHANG, L. (2024) · EXPERIMENTAL ANIMALS · doi:10.1538/expanim.24-0080 · Cited by 3 · see citing works
Javed, S., Latif, Z., Javed, G. A., Munir, A., Mushtaq, M., Hameed, M., Arshad, M., & Arshad, N. (2025) · Current Microbiology · doi:10.1007/s00284-025-04173-6 · Cited by 3 · see citing works
Phongnu, N., Chonpathompikunlert, P., Singhtho, S., Kumlung, T., Reungpatthanaphong, S., Suttikul, S., Tunsophon, S., & Malakul, W. (2025) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.70094 · Cited by 3 · see citing works
Bourroubey, B., Bettouati, A., Bendjebbar, K., Menad, B., Bourroubey, A. E., & Meddah, B. (2025) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093024600441 · Cited by 2 · see citing works
Chong, S. Y., Raja‐Razali, R. B., Ismail, N. H., Ushidee-Radzi, M. A., Zahia-Azizan, N. A., Manickam, M., Norhisham, D. ‘., Ilham, Z., Reale, A., Nazzaro, S., et al. (2026) · Foods · doi:10.3390/foods15122079 · Cited by 2 · see citing works
Elughi, G. N., Oniha, M. I., Obafemi, Y. D., Akinyosoye, A. D., Ahuekwe, E. F., & Akinduti, P. A. (2024) · Journal of Pure and Applied Microbiology · doi:10.22207/jpam.18.1.28 · Cited by 2 · see citing works
Zhou, M., Xiao, M., Guo, H., Guo, X., Zang, X., Zhang, Q., Yu, L., Zhao, J., Zhai, Q., Tian, F., et al. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.106574 · Cited by 1 · see citing works
Lactobacillus murinus Alleviates High Fructose‐Induced MASLD by Boosting Arginine Production
Mo, X., Zhao, G., Liu, L., Zhen, L., Huang, Q. Y., Wang, Y., Yang, X., Huang, L., Wan, L., Wei, C., et al. (2026) · Food Science & Nutrition · doi:10.1002/fsn3.71502 · Cited by 1 · see citing works
Jiang, J., Zhang, Y., Zheng, C., Zhang, S., Ding, Y., Liang, Y., Huang, J., Chai, X., Lin, B., Sun, J., et al. (2026) · Current Molecular Pharmacology · doi:10.1016/j.cmp.2026.03.005 · Cited by 1 · see citing works
A Review on the Resistance of Probiotic Microorganisms to Antibiotics
Ram, A., Bhattacharjee, D., Alam, S. M., Jana, S., & Pal, R. (2024) · Asian Journal of Pharmacy and Technology · doi:10.52711/2231-5713.2024.00054 · Cited by 1 · see citing works
Colón, A. M., Meneses-Mayo, M., & Ahuacatitan, L. L. (2023) · Proceedings of Scientific Research Universidad Anáhuac Multidisciplinary Journal of Healthcare · doi:10.36105/psrua.2023v3n6.02
Lipid metabolism correction with statins and probiotics
Baryshnikova, N. V., Vm, L., Uspenskiy, Y. P., Suvorov, A. N., & Ермоленко, Е. И. (2025) · Экспериментальная и клиническая гастроэнтерология · doi:10.31146/1682-8658-ecg-229-9-161-174
Никитина, Е. В. (2025) · Current Research in Nutrition and Food Science Journal · doi:10.12944/crnfsj.13.2.11
A sequential multi‐strain inoculation approach for designing functional Sicilian table olives
Zingale, I. M., Vaccalluzzo, A., Checco, G. A. C., Marino, V. M., Caccamo, M., Randazzo, C. L., Russo, N., Dikmetaş, D. N., Esatbeyoglu, T., Çapanoğlu, E., et al. (2025) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.70180
Almatrafi, M. M., Nada, A. H., Doghish, A. S., Elebeedy, D., Ghanem, A., Fayad, E., El-Mekkawy, H. I., Mohammed, O. A., Elkhawaga, S. Y., Alshaya, D. S., et al. (2025) · Folia Microbiologica · doi:10.1007/s12223-025-01346-5
Chriaa, O., Amor, M. G.-B., Mathlouthi, N. E. H., Slima, A. B., Mhalhel, K., Turki, M., Kacem, F. H., Germanà, A., Ali, M. B., & Gdoura, R. (2026) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-026-04816-1
Xu, Z., Sun, Z., Wang, F., Han, Q., Li, S., Xue, C., Li, Y., Liu, D., Cai, J., & Sun, H. (2026) · Foods · doi:10.3390/foods15091508
Kılınç, G. E., & Söğüt, M. Ü. (2026) · Food Science & Nutrition · doi:10.1002/fsn3.71967
Altınöz, E., Kayılı, H. M., Çetinavcı, D., Biçer, Y., Najım, N. A., Aydin, H., Üğe, M., & Elbe, H. (2026) · Biological Rhythm Research · doi:10.1080/09291016.2026.2720352
- Authors
- Zafar, H., Ain, N. U., Alshammari, A., Alghamdi, S., Raja, H., Ali, A., Siddique, A., Tahir, S. D., Akbar, S., Arif, M., Alharbi, M., & Rahman, A.
- Affiliations
- National University of Sciences and Technology (PK)
- King Saud University (SA)
- Security Forces Hospital (SA)
- Université de Lorraine (FR)
- Department of Clinical Nutrition, Rawalpindi Institute of Cardiology, Rawalpindi 46000, Pakistan
- Corresponding author
- Alharbi, Metab
- Rahman, Abdur
- ORCID
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2022-04-15
- Volume
- 14
- Issue
- 8
- Pages
- 1654
- ISSN
- 2072-6643 (ISSN-L)
- PMC
- PMC9027066
- OpenAlex
- W4224289317
- Cited by
- 41
- References
- 51
- Citations by year
- 2026: 7 · 2025: 13 · 2024: 10 · 2023: 10 · 2022: 1
- FWCI
- 4.52
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Nutrients (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Keywords
- Lactobacillus rhamnosus, Lactobacillus fermentum, probiotics, cholesterol-lowering effect, lipid profile, high-fat high-cholesterol diet, statin comparison, HDL cholesterol, LDL cholesterol, triglycerides, anti-obesity, dahi, lassi, yogurt, probiotic safety, bacterial translocation
- MeSH terms
- Animals, Cholesterol, Hypercholesterolemia, Lactobacillus, Lipids, Male, Obesity, Rats, Wistar, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Probiotics, Rats, Limosilactobacillus fermentum, Lacticaseibacillus rhamnosus, Diet, High-Fat
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
