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Exercise: A Possibly Effective Way to Improve Vitamin D Nutritional Status

Zhang, Jinghua, Cao, Zhen-Bo·2022·Nutrients

Abstract

Vitamin D deficiency has become a widespread public health problem owing to its potential adverse health effects. Generally, the nutritional status of vitamin D depends on sunlight exposure and dietary or supplementary intake. However, recent studies have found that exercise can influence circulating 25(OH)D levels; although, the results have been inconclusive. In this review, we focused on the effect of exercise on circulating vitamin D metabolites and their possible mechanisms. We found that endurance exercise can significantly increase serum 25(OH)D levels in vitamin D-deficient people but has no significant effect on vitamin D-sufficient people. This benefit has not been observed with resistance training. Only chronic endurance exercise training can significantly increase serum 1,25(OH)2D, and the effect may be sex-dependent. Exercise may influence 25(OH)D levels in the circulation by regulating either the vitamin D metabolites stored in tissues or the utilization by target tissues. The effects of exercise on 25(OH)D levels in the circulation may be dependent on many factors, such as the vitamin D nutritional status, exercise type and intensity, and sex. Therefore, further research on the effects and mechanisms of exercise on vitamin D metabolites is required.

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Metadata

Authors
Zhang, J., & Cao, Z.-B.
Affiliations
Shanghai Frontiers Science Research Base of Exercise and Metabolic Health, Shanghai University of Sport, Shanghai 200438, China
Venue
Nutrients
Publisher
MDPI AG
Published
2022-06-27
Volume
14
Issue
13
Pages
2652
ISSN
2072-6643
Cited by
43
References
5
Language
en
Funders
National Natural Science Foundation of Shanghai (20ZR1454400)

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