CoChat
Sign Up
Cited by 31Microbial bioremediation and biosurfactantsMicrobial Metabolic Engineering and BioproductionSteroid Chemistry and Biochemistry

Synthetic Biology: A New Era in Hydrocarbon Bioremediation

Open access
Jiménez-Díaz, Valentina, Pedroza-Rodríguez, Aura Marina, Ramos-Monroy, Oswaldo, Castillo-Carvajal, Laura C.·2022·Processes
DOI 10.3390/pr10040712
Open this paper in CoChat — free accountOpen PDF

Abstract

Crude oil is a viscous dark liquid resource composed by a mix of hydrocarbons which, after refining, is used for the elaboration of distinct products. A major concern is that many petroleum components are highly toxic due to their teratogenic, hemotoxic, and carcinogenic effects, becoming an environmental concern on a global scale, which must be solved through innovative, efficient, and sustainable techniques. One of the most widely used procedures to totally degrade contaminants are biological methods such as bioremediation. Synthetic biology is a scientific field based on biology and engineering principles, with the purpose of redesigning and restructuring microorganisms to optimize or create new biological systems with enhanced features. The use of this discipline offers improvement of bioremediation processes. This article will review some of the techniques that use synthetic biology as a platform to be used in the area of hydrocarbon bioremediation.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.3390/pr10040712

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The transfer of engineered metabolic pathways could alter nutrient cycles or create unintended selective pressures within microbial communities.

    “For example, the transfer of engineered metabolic pathways could alter nutrient cycles or create unintended selective pressures within microbial communities [166,172].”

    From Harnessing bacterial consortia for effective bioremediation: targeted removal of heavy metals, hydrocarbons, and persistent pollutants (2025) · cites this paper as [172]

    Section 3 describes engineered degradative pathways carried on plasmids that can undergo horizontal gene transfer. Section 6 says recombinant genes may reach indigenous microorganisms and discusses competition with native species, but it does not say that such transfer alters nutrient cycles or creates selective pressures within microbial communities. (LLM, conf=0.84)

    Experimental — accuracy not yet measured

  • Synthetic genes introduced into engineered microbes may transfer to native microorganisms, potentially resulting in the spread of novel traits with unforeseen ecological consequences.

    “Synthetic genes introduced into engineered microbes may transfer to native microorganisms, potentially resulting in the spread of novel traits with unforeseen ecological consequences.”

    From Harnessing bacterial consortia for effective bioremediation: targeted removal of heavy metals, hydrocarbons, and persistent pollutants (2025) · cites this paper as [172]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 83

  1. Speight, J.G.; El-Gendy, N.S. (Eds.) Chapter 1-Petroleum Composition and Properties. In Introduction to Petroleum Biotechnology; Gulf Professional Publishing: Boston, MA, USA, 2018; pp. 1-39.
  2. Varjani, S.J. Microbial degradation of petroleum hydrocarbons. Bioresour. Technol. 2017, 223, 277-286. [CrossRef] [PubMed] · DOI
  3. Selley, R.C.; Sonnenberg, S.A. (Eds.) Chapter 2-The Physical and Chemical Properties of Petroleum. In Elements of Petroleum Geology, 3rd ed.; Academic Press: Boston, MA, USA, 2015; pp. 13-39.
  4. Bilal, M.; Iqbal, H.M.N. Microbial-derived biosensors for monitoring environmental contaminants: Recent advances and future outlook. Process Saf. Environ. Prot. 2019, 124, 8-17. [CrossRef] · DOI
  5. Wu, M.; Wu, J.; Zhang, X.; Ye, X. Effect of bioaugmentation and biostimulation on hydrocarbon degradation and microbial community composition in petroleum-contaminated loessal soil. Chemosphere 2019, 237, 124456. [CrossRef] [PubMed] · DOI
  6. Xiang, L.; Li, G.; Wen, L.; Su, C.; Liu, Y.; Tang, H.; Dai, J. Biodegradation of aromatic pollutants meets synthetic biology. Synth. Syst. Biotechnol. 2021, 6, 153-162. [CrossRef] · DOI
  7. Baniasadi, M.; Mousavi, S.M. A Comprehensive Review on the Bioremediation of Oil Spills. In Microbial Action on Hydrocarbons;
  8. Jaiswal, S.; Shukla, P. Alternative Strategies for Microbial Remediation of Pollutants via Synthetic Biology. Front. Microbiol. 2020, 11, 808. [CrossRef] [PubMed] · DOI · Paper page
  9. Kumari, A.; Chaudhary, D.R. 21-Engineered microbes and evolving plastic bioremediation technology. In Bioremediation of Pollutants; Pandey, V.C., Singh, V., Eds.; Elsevier: Amsterdam, The Netherlands, 2020; pp. 417-443.
  10. Imam, A.; Suman, S.K.; Ghosh, D.; Kanaujia, P.K. Analytical approaches used in monitoring the bioremediation of hydrocarbons in petroleum-contaminated soil and sludge. TrAC Trends Anal. Chem. 2019, 118, 50-64. [CrossRef] · DOI
  11. Pal, A.K.; Singh, J.; Soni, R.; Tripathi, P.; Kamle, M.; Tripathi, V.; Kumar, P. 10-The role of microorganism in bioremediation for sustainable environment management. In Bioremediation of Pollutants; Pandey, V.C., Singh, V., Eds.; Elsevier: Amsterdam, The Netherlands, 2020; pp. 227-249.
  12. Azubuike, C.C.; Chikere, C.B.; Okpokwasili, G.C. Bioremediation techniques-classification based on site of application: Principles, advantages, limitations and prospects. World J. Microbiol. Biotechnol. 2016, 32, 180. [CrossRef] · DOI
  13. Myazin, V.A.; Korneykova, M.V.; Chaporgina, A.A.; Fokina, N.V.; Vasilyeva, G.K. The Effectiveness of Biostimulation, Bioaugmen- tation and Sorption-Biological Treatment of Soil Contaminated with Petroleum Products in the Russian Subarctic. Microorganisms 2021, 9, 1722. [CrossRef] · DOI
  14. Ossai, I.C.; Ahmed, A.; Hassan, A.; Hamid, F.S. Remediation of soil and water contaminated with petroleum hydrocarbon: A review. Environ. Technol. Innov. 2020, 17, 100526. [CrossRef] · DOI
  15. Sakshi; Singh, S.K.; Haritash, A.K. Polycyclic aromatic hydrocarbons: Soil pollution and remediation. Int. J. Environ. Sci. Technol. 2019, 16, 6489-6512. [CrossRef] · DOI
  16. Yaman, C. Performance and Kinetics of Bioaugmentation, Biostimulation, and Natural Attenuation Processes for Bioremediation of Crude Oil-Contaminated Soils. Processes 2020, 8, 883. [CrossRef] · DOI
  17. Cai, Y.; Wang, R.; Rao, P.; Wu, B.; Yan, L.; Hu, L.; Park, S.; Ryu, M.; Zhou, X. Bioremediation of Petroleum Hydrocarbons Using Acinetobacter sp. SCYY-5 Isolated from Contaminated Oil Sludge: Strategy and Effectiveness Study. Int. J. Environ. Res. Public Health 2021, 18, 819. [CrossRef] [PubMed] · DOI
  18. Hussain, A.; Rehman, F.; Rafeeq, H.; Waqas, M.; Asghar, A.; Afsheen, N.; Rahdar, A.; Bilal, M.; Iqbal, H.M.N. In-situ, Ex-situ, and nano-remediation strategies to treat polluted soil, water, and air-A review. Chemosphere 2022, 289, 133252. [CrossRef] [PubMed] · DOI
  19. Jørgensen, K.S.; Puustinen, J.; Suortti, A.-M. Bioremediation of petroleum hydrocarbon-contaminated soil by composting in biopiles. Environ. Pollut. 2000, 107, 245-254. [CrossRef] · DOI
  20. Benyahia, F.; Embaby, A.S. Bioremediation of Crude Oil Contaminated Desert Soil: Effect of Biostimulation, Bioaugmentation and Bioavailability in Biopile Treatment Systems. Int. J. Environ. Res. Public Health 2016, 13, 219. [CrossRef] [PubMed] · DOI
  21. Steliga, T.; Kluk, D. Assessment of the Suitability of Melilotus officinalis for Phytoremediation of Soil Contaminated with Petroleum Hydrocarbons (TPH and PAH), Zn, Pb and Cd Based on Toxicological Tests. Toxics 2021, 9, 148. [CrossRef] [PubMed] · DOI
  22. Xu, X.; Liu, W.; Tian, S.; Wang, W.; Qi, Q.; Jiang, P.; Gao, X.; Li, F.; Li, H.; Yu, H. Petroleum Hydrocarbon-Degrading Bacteria for the Remediation of Oil Pollution Under Aerobic Conditions: A Perspective Analysis. Front. Microbiol. 2018, 9, 2885. [CrossRef] · DOI
  23. Jariyal, M.; Yadav, M.; Singh, N.K.; Yadav, S.; Sharma, I.; Dahiya, S.; Thanki, A. 8-Microbial remediation progress and future prospects. In Bioremediation of Pollutants; Pandey, V.C., Singh, V., Eds.; Elsevier: Amsterdam, The Netherlands, 2020; pp. 187-214.
  24. Sharma, B.; Shukla, P. Designing synthetic microbial communities for effectual bioremediation: A review. Biocatal. Biotransform. 2020, 38, 405-414. [CrossRef] · DOI
  25. Rylott, E.L.; Bruce, N.C. How synthetic biology can help bioremediation. Curr. Opin. Chem. Biol. 2020, 58, 86-95. [CrossRef] · DOI
  26. Xin, F.; Dong, W.; Dai, Z.; Jiang, Y.; Yan, W.; Lv, Z.; Fang, Y.; Jiang, M. Chapter 9-Biosynthetic Technology and Bioprocess Engineering. In Current Developments in Biotechnology and Bioengineering;
  27. Bhattacharjee, G.; Gohil, N.; Singh, V. 14-Synthetic biology approaches for bioremediation. In Bioremediation of Pollutants; Pandey, V.C., Singh, V., Eds.; Elsevier: Amsterdam, The Netherlands, 2020; pp. 303-312.
  28. Meng, L.; Bao, M.; Sun, P. Construction of long-chain alkane degrading bacteria and its application in bioremediation of crude oil pollution. Int. J. Biol. Macromol. 2018, 119, 524-532. [CrossRef] · DOI
  29. Liu, J.; Zhao, B.; Lan, Y.; Ma, T. Enhanced degradation of different crude oils by defined engineered consortia of Acinetobacter venetianus RAG-1 mutants based on their alkane metabolism. Bioresour. Technol. 2021, 327, 124787. [CrossRef] [PubMed] · DOI
  30. Samin, G.; Pavlova, M.; Arif, M.I.; Postema, C.P.; Damborsky, J.; Janssen, D.B. A Pseudomonas putida strain genetically engineered for 1,2,3-trichloropropane bioremediation. Appl. Environ. Microbiol. 2014, 80, 5467-5476. [CrossRef] [PubMed] · DOI
  31. Xie, Y.; Yu, F.; Wang, Q.; Gu, X.; Chen, W. Cloning of Catechol 2,3-Dioxygenase Gene and Construction of a Stable Genetically Engineered Strain for Degrading Crude Oil. Indian J. Microbiol. 2014, 54, 59-64. [CrossRef] [PubMed] · DOI
  32. Kim, J.; Salvador, M.; Saunders, E.; González, J.; Avignone-Rossa, C.; Jiménez, J.I. Properties of alternative microbial hosts used in synthetic biology: Towards the design of a modular chassis. Essays Biochem. 2016, 60, 303-313. [PubMed]
  33. Chi, H.; Wang, X.; Shao, Y.; Qin, Y.; Deng, Z.; Wang, L.; Chen, S. Engineering and modification of microbial chassis for systems and synthetic biology. Synth. Syst. Biotechnol. 2019, 4, 25-33. [CrossRef] [PubMed] · DOI
  34. McCarty, N.S.; Ledesma-Amaro, R. Synthetic Biology Tools to Engineer Microbial Communities for Biotechnology. Trends Biotechnol. 2019, 37, 181-197. [CrossRef] · DOI
  35. Göpfrich, K.; Platzman, I.; Spatz, J.P. Mastering Complexity: Towards Bottom-up Construction of Multifunctional Eukaryotic Synthetic Cells. Trends Biotechnol. 2018, 36, 938-951. [CrossRef] · DOI
  36. Mutschler, H.; Robinson, T.; Tang, T.-D.; Wegner, S. Special Issue on Bottom-Up Synthetic Biology. ChemBioChem 2019, 20, 2533-2534. [CrossRef] · DOI
  37. Roberts, M.A.J.; Cranenburgh, R.M.; Stevens, M.P.; Oyston, P.C.F. Synthetic biology: Biology by design. Microbiology 2013, 159, 1219-1220. [CrossRef] · DOI
  38. Varjani, S.J.; Upasani, V.N. A new look on factors affecting microbial degradation of petroleum hydrocarbon pollutants. Int. Biodeterior. Biodegrad. 2017, 120, 71-83. [CrossRef] · DOI
  39. Hussain, I.; Aleti, G.; Naidu, R.; Puschenreiter, M.; Mahmood, Q.; Rahman, M.M.; Wang, F.; Shaheen, S.; Syed, J.H.; Reichenauer, T.G. Microbe and plant assisted-remediation of organic xenobiotics and its enhancement by genetically modified organisms and recombinant technology: A review. Sci. Total Environ. 2018, 628-629, 1582-1599. [CrossRef] [PubMed] · DOI
  40. Tran, K.M.; Lee, H.; Thai, T.D.; Shen, J.; Eyun, S.; Na, D. Synthetically engineered microbial scavengers for enhanced bioremedia- tion. J. Hazard. Mater. 2021, 419, 126516. [CrossRef] [PubMed] · DOI
  41. Chaudhary, D.K.; Kim, J. New insights into bioremediation strategies for oil-contaminated soil in cold environments. Int. Biodeterior. Biodegrad. 2019, 142, 58-72. [CrossRef] · DOI
  42. Kumar, A.; Singh, R.; Kumar, A.; Rai, R.; Singh, V.; Bhadouria, R. Genetically engineered bacteria for the degradation of dye and other organic compounds. In Abatement of Environmental Pollutants; Singh, P., Kumar, A., Borthakur, A., Eds.; Elsevier: Amsterdam, The Netherlands, 2020; pp. 331-350.
  43. Pant, G.; Garlapati, D.; Agrawal, U.; Prasuna, R.G.; Mathimani, T.; Pugazhendhi, A. Biological approaches practised using genetically engineered microbes for a sustainable environment: A review. J. Hazard. Mater. 2021, 405, 124631. [CrossRef] [PubMed] · DOI · Paper page
  44. Liu, L.; Bilal, M.; Duan, X.; Iqbal, H.M.N. Mitigation of environmental pollution by genetically engineered bacteria-Current challenges and future perspectives. Sci. Total Environ. 2019, 667, 444-454. [CrossRef] · DOI
  45. Miri, S.; Naghdi, M.; Rouissi, T.; Kaur Brar, S.; Martel, R. Recent biotechnological advances in petroleum hydrocarbons degradation under cold climate conditions: A review. Crit. Rev. Environ. Sci. Technol. 2019, 49, 553-586. [CrossRef] · DOI
  46. Boronin, A.M.; Kosheleva, I.A. The Role of Catabolic Plasmids in Biodegradation of Petroleum Hydrocarbons. In Current Environmental Issues and Challenges; Cao, G., Orrù, R., Eds.; Springer: Dordrecht, The Netherlands, 2014; pp. 159-168.
  47. Bhatt, P.; Bhandari, G.; Bhatt, K.; Maithani, D.; Mishra, S.; Gangola, S.; Bhatt, R.; Huang, Y.; Chen, S. Plasmid-mediated catabolism for the removal of xenobiotics from the environment. J. Hazard. Mater. 2021, 420, 126618. [CrossRef] · DOI
  48. Emamalipour, M.; Seidi, K.; Zununi Vahed, S.; Jahanban-Esfahlan, A.; Jaymand, M.; Majdi, H.; Amoozgar, Z.; Chitkushev, L.T.; Javaheri, T.; Jahanban-Esfahlan, R.; et al. Horizontal Gene Transfer: From Evolutionary Flexibility to Disease Progression. Front. Cell Dev. Biol. 2020, 8, 229. [CrossRef] · DOI · Paper page
  49. Maloy, S., Hughes, K., Eds.; Academic Press: San Diego, CA, USA, 2013; pp. 530-532.
  50. Abbasian, F.; Lockington, R.; Megharaj, M.; Naidu, R. A Review on the Genetics of Aliphatic and Aromatic Hydrocarbon Degradation. Appl. Biochem. Biotechnol. 2016, 178, 224-250. [CrossRef] · DOI
  51. Wang, B.; Xu, J.; Gao, J.; Fu, X.; Han, H.; Li, Z.; Wang, L.; Tian, Y.; Peng, R.; Yao, Q. Construction of an Escherichia coli strain to degrade phenol completely with two modified metabolic modules. J. Hazard. Mater. 2019, 373, 29-38. [CrossRef] · DOI
  52. Jones, J.A.; Koffas, M.A.G. Chapter Eight-Optimizing Metabolic Pathways for the Improved Production of Natural Products. Meth. Enzymol. 2016, 575, 179-193.
  53. Jain, C.K.; Gupta, M.; Prasad, Y.; Wadhwa, G.; Sharma, S.K. Homology modeling and protein engineering of alkane monooxyge- nase in Burkholderia thailandensis MSMB121: In silico insights. J. Mol. Model. 2014, 20, 2340-2343. [CrossRef] [PubMed] · DOI
  54. Dueber, J.E.; Wu, G.C.; Malmirchegini, G.R.; Moon, T.S.; Petzold, C.J.; Ullal, A.V.; Prather, K.L.J.; Keasling, J.D. Synthetic protein scaffolds provide modular control over metabolic flux. Nat. Biotechnol. 2009, 27, 753-759. [CrossRef] · DOI
  55. Jiang, B.; Song, Y.; Liu, Z.; Huang, W.E.; Li, G.; Deng, S.; Xing, Y.; Zhang, D. Whole-cell bioreporters for evaluating petroleum hydrocarbon contamination. Crit. Rev. Environ. Sci. Technol. 2021, 51, 272-322. [CrossRef] · DOI
  56. Behera, B.K.; Das, A.; Sarkar, D.J.; Weerathunge, P.; Parida, P.K.; Das, B.K.; Thavamani, P.; Ramanathan, R.; Bansal, V. Polycyclic Aromatic Hydrocarbons (PAHs) in inland aquatic ecosystems: Perils and remedies through biosensors and bioremediation. Environ. Pollut. 2018, 241, 212-233. [CrossRef] [PubMed] · DOI
  57. Nandimandalam, H.; Gude, V.G. Indigenous biosensors for in situ hydrocarbon detection in aquatic environments. Mar. Pollut. Bull. 2019, 149, 110643. [CrossRef] · DOI
  58. Paitan, Y.; Biran, I.; Shechter, N.; Biran, D.; Rishpon, J.; Ron, E.Z. Monitoring aromatic hydrocarbons by whole cell electrochemical biosensors. Anal. Biochem. 2004, 335, 175-183. [CrossRef] · DOI
  59. Rajkumar, P.; Ramprasath, T.; Selvam, G.S. 12-A simple whole cell microbial biosensors to monitor soil pollution. In New Pesticides and Soil Sensors; Grumezescu, A.M., Ed.; Academic Press: Cambridge, MA, USA, 2017; pp. 437-481.
  60. Nigam, V.K.; Pratyoosh, S. Enzyme Based Biosensors for Detection of Environmental Pollutants-A Review. J. Microbiol. Biotechnol. 2015, 25, 1773-1781. [CrossRef] · DOI
  61. Voon, C.H.; Yusop, N.M.; Khor, S.M. The state-of-the-art in bioluminescent whole-cell biosensor technology for detecting various organic compounds in oil and grease content in wastewater: From the lab to the field. Talanta 2022, 241, 123271. [CrossRef] · DOI
  62. Moratti, C.F.; Scott, C.; Coleman, N.V. Synthetic Biology Approaches to Hydrocarbon Biosensors: A Review. Front. Bioeng. Biotechnol. 2022, 9, 804234. [CrossRef] · DOI
  63. Tecon, R.; Van der Meer, J.R. Bacterial Biosensors for Measuring Availability of Environmental Pollutants. Sensors 2008, 8, 4062-4080. [CrossRef] · DOI
  64. Plotnikova, E.G.; Shumkova, E.S.; Shumkov, M.S. Whole-cell bacterial biosensors for the detection of aromatic hydrocarbons and their chlorinated derivatives. Appl. Biochem. Microbiol. 2016, 52, 347-357. [CrossRef] · DOI
  65. Patel, R.; Zaveri, P.; Mukherjee, A.; Agarwal, P.K.; More, P.; Munshi, N.S. Development of fluorescent protein-based biosensing strains: A new tool for the detection of aromatic hydrocarbon pollutants in the environment. Ecotoxicol. Environ. Saf. 2019, 182, 109450. [CrossRef] [PubMed] · DOI
  66. Roy, R.; Ray, S.; Chowdhury, A.; Anand, R. Tunable Multiplexed Whole-Cell Biosensors as Environmental Diagnostics for ppb-Level Detection of Aromatic Pollutants. ACS Sens. 2021, 6, 1933-1939. [CrossRef] [PubMed] · DOI
  67. Padmaperuma, G.; Butler, T.; Shuhaili, F.; Almalki, W.; Vaidyanathan, S. Microbial consortia: Concept and application in fruit crop management. In Fruit Crops; Elsevier: Amsterdam, The Netherlands, 2020; pp. 353-366.
  68. Kong, W.; Meldgin, D.R.; Collins, J.J.; Lu, T. Designing microbial consortia with defined social interactions. Nat. Chem. Biol. 2018, 14, 821-829. [CrossRef] · DOI · Paper page
  69. Zhang, Z.; Yan, C.; Zhang, H. Mutualism between antagonists: Its ecological and evolutionary implications. Integr. Zool. 2021, 16, 84-96. [CrossRef] · DOI
  70. Drew, G.C.; Stevens, E.J.; King, K.C. Microbial evolution and transitions along the parasite-mutualist continuum. Nat. Rev. Microbiol. 2021, 19, 623-638. [CrossRef] · DOI
  71. Bidja Abena, M.T.; Sodbaatar, N.; Li, T.; Damdinsuren, N.; Choidash, B.; Zhong, W. Crude Oil Biodegradation by Newly Isolated Bacterial Strains and Their Consortium Under Soil Microcosm Experiment. Appl. Biochem. Biotechnol. 2019, 189, 1223-1244. [CrossRef] · DOI
  72. Qian, X.; Chen, L.; Sui, Y.; Chen, C.; Zhang, W.; Zhou, J.; Dong, W.; Jiang, M.; Xin, F.; Ochsenreither, K. Biotechnological potential and applications of microbial consortia. Biotechnol. Adv. 2020, 40, 107500. [CrossRef] · DOI
  73. Srivastava, A.K.; Singh, R.K.; Singh, D. Chapter 20-Microbe-based bioreactor system for bioremediation of organic contaminants: Present and future perspective. In Microbe Mediated Remediation of Environmental Contaminants; Kumar, A., Singh, V.K., Singh, P., Mishra, V.K., Eds.; Woodhead Publishing: Sawston, UK, 2021; pp. 241-253.
  74. Chen, W.; Kong, Y.; Li, J.; Sun, Y.; Min, J.; Hu, X. Enhanced biodegradation of crude oil by constructed bacterial consortium comprising salt-tolerant petroleum degraders and biosurfactant producers. Int. Biodeterior. Biodegrad. 2020, 154, 105047. [CrossRef] · DOI
  75. Guo, G.; Tian, F.; Ding, K.; Wang, L.; Liu, T.; Yang, F. Effect of a bacterial consortium on the degradation of polycyclic aromatic hydrocarbons and bacterial community composition in Chinese soils. Int. Biodeterior. Biodegrad. 2017, 123, 56-62. [CrossRef] · DOI
  76. Xu, C.; Yu, H. Insights into constructing a stable and efficient microbial consortium. Chin. J. Chem. Eng. 2021, 30, 112-120. [CrossRef] · DOI
  77. Jia, X.; He, Y.; Jiang, D.; Liu, C.; Lu, W. Construction and analysis of an engineered Escherichia coli-Pseudomonas aeruginosa co-culture consortium for phenanthrene bioremoval. Biochem. Eng. J. 2019, 148, 214-223. [CrossRef] · DOI
  78. Wu, C.; Li, F.; Yi, S.; Ge, F. Genetically engineered microbial remediation of soils co-contaminated by heavy metals and polycyclic aromatic hydrocarbons: Advances and ecological risk assessment. J. Environ. Manag. 2021, 296, 113185. [CrossRef] · DOI
  79. Wang, F.; Zhang, W. Synthetic biology: Recent progress, biosafety and biosecurity concerns, and possible solutions. J. Biosaf. Biosecurity 2019, 1, 22-30. [CrossRef] · DOI
  80. de Lorenzo, V. Environmental biosafety in the age of Synthetic Biology: Do we really need a radical new approach? Bioessays 2010, 32, 926-931. [CrossRef] · DOI
  81. Cases, I.; de Lorenzo, V. Genetically modified organisms for the environment: Stories of success and failure and what we have learned from them. Int Microbiol. 2005, 8, 213-222.
  82. Torres, L.; Krüger, A.; Csibra, E.; Gianni, E.; Pinheiro, V.B. Synthetic biology approaches to biological containment: Pre-emptively tackling potential risks. Essays Biochem. 2016, 60, 393-410.
  83. Kim, D.; Lee, J.W. Genetic Biocontainment Systems for the Safe Use of Engineered Microorganisms. Biotechnol. Bioprocess Eng. 2020, 25, 974-984. [CrossRef] · DOI

Cited by

Sorted by citations

Authors
Jiménez-Díaz, V., Pedroza-Rodríguez, A. M., Ramos-Monroy, O., & Castillo-Carvajal, L. C.
Affiliations
  • Universidad Anáhuac (MX)
  • Pontificia Universidad Javeriana (CO)
  • Instituto Politécnico Nacional (MX)
Corresponding author
Castillo-Carvajal, Laura C.
ORCID
Venue
Processes
Publisher
MDPI AG
Published
2022-04-06
Volume
10
Issue
4
Pages
712
ISSN
2227-9717 (ISSN-L)
DOI
10.3390/pr10040712
OpenAlex
W4224257725
Cited by
31
References
1
Citations by year
2026: 9 · 2025: 6 · 2024: 10 · 2023: 4 · 2022: 2
FWCI
1.29
Type
journal article
Language
en
Open access
Licence
Locations
  • Processes (publishedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Topics
  • Physical Sciences › Environmental Science › Pollution › Microbial bioremediation and biosurfactants
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Steroid Chemistry and Biochemistry
Keywords
synthetic biology, hydrocarbon bioremediation, crude oil, petroleum hydrocarbons, engineered microorganisms, biodegradation, environmental pollution

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review