The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Inhibition of Quorum Sensing-Controlled Virulence Factor Production in Pseudomonas aeruginosa PAO1 by Ayurveda Spice Clove (Syzygium Aromaticum) Bud Extract
Open accessAbstract
Quorum sensing controls the virulence determinants in most proteobacteria. In this work, the hexane, chloroform and methanol extracts of an Ayurveda spice, namely clove (Syzygium aromaticum), shown anti-quorum sensing activity. Hexane and methanol extracts of clove inhibited the response of C. violaceum CV026 to exogenously supplied N‑hexanoylhomoserine lactone, in turn preventing violacein production. Chloroform and methanol extracts of clove significantly reduced bioluminescence production by E. coli [pSB1075] grown in the presence of N-(3-oxododecanoyl)-L-homoserine lactone. We demonstrated that clove extract inhibited quorum sensing-regulated phenotypes in Pseudomonas aeruginosa PA01, including expression of lecA::lux (by hexane extract), swarming (maximum inhibition by methanol extract), pyocyanin (maximum inhibition by hexane extract). This study shows that the presence of natural compounds that exhibit anti-quorum sensing activity in the clove extracts may be useful as the lead of anti-infective drugs.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Khan, M. S. A., Zahin, M., Hasan, S., Husain, F. M., & Ahmad, I. (2009) · Letters in Applied Microbiology · doi:10.1111/j.1472-765x.2009.02666.x · Cited by 279
Cited by
Essential Oils, A New Horizon in Combating Bacterial Antibiotic Resistance
Yap, P. S. X., Yiap, B. C., Ping, H. C., & Lim, S. H. E. (2014) · The Open Microbiology Journal · doi:10.2174/1874285801408010006 · Cited by 426
Ouyang, J., Sun, F., Feng, W., Sun, Y., Qiu, X., Xiong, L., Liu, Y., & Chen, Y. (2016) · Journal of Applied Microbiology · doi:10.1111/jam.13073 · Cited by 286
Liu, K., Wang, X., Sha, K., Zhang, F., Xiong, F., Wang, X., Chen, J., Li, J., Churilov, L. P., Chen, S., et al. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.04.007 · Cited by 23
Metadata
- Authors
- Krishnan, T., Yin, W.-F., & Chan, K.-G.
- Venue
- Sensors
- Publisher
- MDPI AG
- Published
- 2012-03-27
- Volume
- 12
- Issue
- 4
- Pages
- 4016-4030
- ISSN
- 1424-8220 (ISSN-L)
- OpenAlex
- W2146399628
- Cited by
- 176
- References
- 1
- FWCI
- 5.81
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Inhibition of Quorum Sensing-Controlled Virulence Factor Production in Pseudomonas aeruginosa PAO1 by Ayurveda Spice Clove (Syzygium Aromaticum) Bud Extract. https://app.cochat.ai/papers/10.3390/s120404016
- The paper
- Krishnan, T., Yin, W.-F., & Chan, K.-G. (2012). Inhibition of Quorum Sensing-Controlled Virulence Factor Production in Pseudomonas aeruginosa PAO1 by Ayurveda Spice Clove (Syzygium Aromaticum) Bud Extract. Sensors. https://doi.org/10.3390/s120404016
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
