Cited by 218Redox biology and oxidative stressCancer and biochemical researchAntioxidant Activity and Oxidative Stress

The DOI matches its Crossref record; 107 of the 107 references it cites were found in a registry or an index.

Chemistry of Hydrogen Peroxide Formation and Elimination in Mammalian Cells, and Its Role in Various Pathologies

Open access

Andrés, Celia María Curieses, Pérez de la Lastra, José Manuel, Juan, Celia Andrés, Plou, Francisco J., Pérez-Lebeña, Eduardo·2022·Stresses

DOI 10.3390/stresses2030019

Open this paper in CoChat — free account Open PDF

Abstract

Hydrogen peroxide (H2O2) is a compound involved in some mammalian reactions and processes. It modulates and signals the redox metabolism of cells by acting as a messenger together with hydrogen sulfide (H2S) and the nitric oxide radical (•NO), activating specific oxidations that determine the metabolic response. The reaction triggered determines cell survival or apoptosis, depending on which downstream metabolic pathways are activated. There are several ways to produce H2O2 in cells, and cellular systems tightly control its concentration. At the cellular level, the accumulation of hydrogen peroxide can trigger inflammation and even apoptosis, and when its concentration in the blood reaches toxic levels, it can lead to bioenergetic failure. This review summarizes existing research from a chemical perspective on the role of H2O2 in various enzymatic pathways and how this biochemistry leads to physiological or pathological responses.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.3390/stresses2030019

Cites

107 of 107 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Free Radicals in Biology and Medicine
Halliwell, B., & Gutteridge, J. M. C. (2015) · doi:10.1093/acprof:oso/9780198717478.001.0001 · Cited by 8,990
NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses
Ghosh, S., May, M. J., & Kopp, E. B. (1998) · Annual Review of Immunology · doi:10.1146/annurev.immunol.16.1.225 · Cited by 5,182
Heavy Metal Pollution in the Environment and Their Toxicological Effects on Humans
Briffa, J., Sinagra, E., & Blundell, R. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e04691 · Cited by 4,402
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
Zanger, U. M., & Schwab, M. (2013) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2012.12.007 · Cited by 4,169
ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis
D'Autréaux, B., & Toledano, M. B. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2256 · Cited by 3,642
Reactive oxygen species in cancer
Liou, G., & Störz, P. (2010) · Free Radical Research · doi:10.3109/10715761003667554 · Cited by 3,528
Untitled work
Fridovich (1978) · doi:10.1126/science.210504 · Cited by 3,329
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4.
Nordberg, J., & Arnér, E. S. J. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00724-9 · Cited by 2,720
Physiological Roles of Mitochondrial Reactive Oxygen Species
Sena, L. A., & Chandel, N. S. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.09.025 · Cited by 2,632
Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress
Sies, H. (2017) · Redox Biology · doi:10.1016/j.redox.2016.12.035 · Cited by 2,148

Show all 107 references

Research works printed but not linked: 3

Ren, J., Sowers, J.R., and Zhang, Y. (2018). Autophagy and Cardiometabolic Diseases: From Molecular Mechanisms to Translational Medicine, Elsevier.
Nriagu, J.O. (2011). Encyclopedia of Environmental Health, Elsevier.
Preedy, V.R. (2020). Chapter 1—Free radicals: What they are and what they do. Pathology, Academic Press.

Sorted by citations

Items 101–200 of 218

Algae as a Functional Food: A Case Study on Spirulina
Stunda-Zujeva, A., & Berele, M. (2023) · Springer eBooks · doi:10.1007/978-3-031-42026-9_17 · Cited by 9
Crosstalk between copper, Alzheimer’s disease, and melatonin
Deepika, Thakur, A., Panghal, A., Pundir, R., Singh, C., Goyal, M., Namdeo, A. G., & Kumar, J. (2025) · BioMetals · doi:10.1007/s10534-025-00712-7 · Cited by 6
High Levels of Superoxide Dismutase 2 Are Associated With Worse Prognosis in Patients With Breast Cancer
de Bastos, D. R., Longatto‐Filho, A., Conceição, M. P. F., & Termini, L. (2024) · European Journal of Breast Health · doi:10.4274/ejbh.galenos.2024.2024-3-6 · Cited by 6
Assessing the therapeutic potential of KK14 peptide derived from Cyprinus Carpio in reducing intercellular ROS levels in oxidative Stress‐Induced In vivo zebrafish larvae model: An integrated bioinformatics, antioxidant, and neuroprotective analysis
Vijayanand, M., Guru, A., Shaik, M. R., Hussain, S. A., & Issac, P. K. (2024) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.70027 · Cited by 6
Mixed-Metal 2D Chalcogenides MoxRe1–xS2 as Antifungal Near-Infrared-Responsive Nanozymes
Zhang, F., Sahani, R., An, C., Na, H., Oyon, S. A., Radu, D. R., McGoron, A. J., & Lai, C. (2024) · ACS Applied Nano Materials · doi:10.1021/acsanm.4c05939 · Cited by 6
Phytochemical Screening and In Vitro Evaluation of the Antioxidant Potential of Dichloromethane Extracts of Strychnos henningsii Gilg. and Ficus sycomorus L.
Wafula, K. W., Mworia, J. K., & Ngugi, M. P. (2023) · The Scientific World JOURNAL · doi:10.1155/2023/8494176 · Cited by 7
In Vivo Assessment of Hepatic and Kidney Toxicity Induced by Silicon Quantum Dots in Mice
Cristian, R.-E., Baltă, C., Herman, H., Trică, B., Sbarcea, G., Hermenean, A. O., Dinischiotu, A., & Stan, M. S. (2024) · Nanomaterials · doi:10.3390/nano14050457 · Cited by 6
Antibacterial activity and synergistic interaction between Artemisia roxburghiana Wall. ex Besser extracts and synthetic antibiotics against resistant clinical isolates
Ali, S. M., Sara-Tun-Nisa, Fatima, H., & Haq, I. U. (2024) · South African Journal of Botany · doi:10.1016/j.sajb.2024.10.035 · Cited by 6
The electrochemical fabrication of Ag nanoparticles decorated poly(l-cysteine) modifed electrode for non-enzymatic H2O2 sensor
Doğan, H. Ö., Ertuğrul, B., Çelebi, N., & Yüksel, A. K. (2025) · Applied Physics A · doi:10.1007/s00339-025-08495-x · Cited by 5
Beyond antioxidants: How ROS-RNS-RSS microdomains encode redox information in health and disease
de la Lastra, J. M. P., Andrés, C. M. C., Munguira, E. B., Andrés, C., & Pérez‐Lebeña, E. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.03.004 · Cited by 5
Self-citation
Superoxidase dismutases (SODs) in the European eel: Gene characterization, expression response to temperature combined with hormonal maturation and possible migratory implications
Morini, M., Ferrão, L., Blanes-García, M., Pérez, L., Asturiano, J. F., & Morini, M. (2024) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2024.111590 · Cited by 7
Immune response, oxidative stress, and histological changes of Wistar rats after being administered with Parascaris equorum antigen
Yehia, S., Badr, A. M., Bashtar, A.-R., Ibrahim, M. A.-A., Mousa, M. R., & Mostafa, N. A. (2024) · Scientific Reports · doi:10.1038/s41598-024-67788-y · Cited by 5
Chiral-Dependent Redox Capacitive Biosensor Using Cu-Cys-GSH Nanoparticles for Ultrasensitive H2O2 Detection
Aydın, D. Y., Wu, J. J., & Chen, J. (2025) · Biosensors · doi:10.3390/bios15050315 · Cited by 5
Hypoglycemic effect of Coffea arabica leaf extracts and major bioactive constituents
do Nascimento, G. O., Marques, S. P. D., Maia, C. E. G., de Sousa, A. F., Cunha, R. L., Malta, M. R., Owen, R. W., Ferreira, M. K. A., da Silva, A. W., Rebouças, E. L., et al. (2023) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2023.2188421 · Cited by 5
Assessment of Artemisia Campestris L. Leaf Extract Effects on Polycystic Ovarian Syndrome in Rats, Antioxidant and α‐Amylase Inhibition Activities
Cherfi, I., Mahboub, N., Toumi, I., Laouini, S. E., Hasan, G. G., Bouafia, A., Alharthi, F. A., & Emran, T. B. (2024) · Chemistry & Biodiversity · doi:10.1002/cbdv.202402184 · Cited by 5
Influence of Pin-to-Plane Discharge Modes on the Physicochemical Properties of Single-Pass Flow-Through Plasma-Activated Water and Its Efficacy in Agricultural Applications
Thana, P., Buppan, P., Theepharaksapan, S., Yooyongsatit, S., Sonhom, W., Pakdee, K., Jinpol, A., Surinsuk, S., Thummaraksa, N., & Matra, K. (2025) · IEEE Access · doi:10.1109/access.2025.3639415 · Cited by 4
Eco-evolutionary dynamics of experimental Pseudomonas aeruginosa populations under oxidative stress
Fu, T., Gifford, D. R., Cg, K., & Brockhurst, M. A. (2023) · Microbiology · doi:10.1099/mic.0.001396 · Cited by 6
Tirzepatide mitigates cognitive decline in zebrafish model of type 2 diabetes mellitus induced by high-fat diet
Misra, S., Rajput, P., & Kaur, A. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-03827-3 · Cited by 5
Critical role of copper ions and active hydrogen for fast reduction of 4-nitrophenol using CuS mesh
Lee, M. G., Selvaraj, R., & Kim, Y. (2025) · Chemical Engineering Science · doi:10.1016/j.ces.2025.121303 · Cited by 4
Redox Regulation of cAMP-Dependent Protein Kinase and Its Role in Health and Disease
Ekhator, E. S., Fazzari, M., & Newman, R. H. (2025) · Life · doi:10.3390/life15040655 · Cited by 5
Determination of Gaseous H2O2 Using UV-Vis Spectroscopy
Modic, A., Filip, L., & Jovanovski, V. (2025) · Chemosensors · doi:10.3390/chemosensors13050157 · Cited by 5
A hidrogén-peroxid paradigmaváltásai a sebészettől a celluláris jelátvitelig
Nagy, I., Kisa-Nagy, V., Bozsó, S., Koller, Á., Ferencz, A., & Debreczeni, B. (2026) · Orvosi Hetilap · doi:10.1556/650.2026.33461 · Cited by 4
Antioxidant Effect of a Fucus vesiculosus Extract on Intestinal Ischemia/Reperfusion Injury in Rats: A Biochemical and Histological Study
Sánchez-Bonet, D., Padrón-Sanz, C., Lloris‐Cejalvo, J. M., Lloris‐Carsí, J. M., & Cejalvo‐Lapeña, D. (2025) · Antioxidants · doi:10.3390/antiox14060624 · Cited by 4
Gold and gold‑platinum clusters as nanocatalysts for conversion of hydrogen peroxide
Zdunek, K., & Wieckowska, A. (2025) · Journal of Electroanalytical Chemistry · doi:10.1016/j.jelechem.2025.119009 · Cited by 3
Modulatory effects of lannea welwitschia on cadmium-induced reproductive and biochemical dysregulation via steroidogenic enzyme regulation in female rats
Eko, O. W., Eteng, M. U., Iwara, I. A., Eteng, K. K., Arikpo, K. E., Ekam, V. S., Igile, G. O., & Eyong, E. U. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.120821 · Cited by 3
Pharmacological targeting of nuclear factor (erythroid-derived 2)-like 2 (NRF2): a potential strategy to improve the efficacy of oncological photodynamic therapy
de Klerk, D. J., de Keijzer, M. J., Franchi, L. P., Tian, J., Gureev, M., Ge, Y., Mesquita, B. S., Saelman, G., herteryck, I. V., Dias, L. M., et al. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.117620 · Cited by 3
Impact of rising temperature on physiological and biochemical alterations that affect the viability of blood cells in American bullfrog crossbreeds
Chaiyasing, R., Jinagool, P., Wipassa, V., Kusolrat, P., & Aengwanich, W. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e32416 · Cited by 3
Assessment of the Environmental Impact of Solid Oil Materials Based on Pyrolysis Oil
Staroń, A., Kijania-Kontak, M., Dziadas, M., & Banach, M. (2023) · Materials · doi:10.3390/ma16175847 · Cited by 3
Synthesis of Bis-Chalcones and Evaluation of Its Effect on Peroxide-Induced Cell Death and Lipopolysaccharide-Induced Cytokine Production
Tom, A., Jacob, J., Mathews, M., Rajagopal, R., Alfarhan, A., Barceló, ‪., & Narayanankutty, A. (2023) · Molecules · doi:10.3390/molecules28176354 · Cited by 3
Effect of aqueous-alcoholic extract of Ducrosia Anethifolia Boiss on the fetal liver of diabetic rats
Jahromi, H. K., Ghasemi, F., & Mikaeiliagah, E. (2024) · World Journal of Traditional Chinese Medicine · doi:10.4103/wjtcm.wjtcm_47_23 · Cited by 3
Chrysin attenuates epithelial prostatic hyperplasia in the ventral prostate of spontaneously hypertensive rats
dos Santos, N. R. L., de Sousa, G. C., de Lima, P. N., Medeiros, B. C. M., Manso, L. A., da Silva, C. R. B., da Silveira, C. C. R., Ghedini, P. C., Campos, H. M., Costa, M. S., et al. (2024) · Cell Biology International · doi:10.1002/cbin.12218 · Cited by 3
Angiotensin II Exposure In Vitro Reduces High Salt-Induced Reactive Oxygen Species Production and Modulates Cell Adhesion Molecules’ Expression in Human Aortic Endothelial Cell Line
Kolobarić, N., Kozina, N., Mihaljević, Z., & Drenjančević, I. (2024) · Biomedicines · doi:10.3390/biomedicines12122741 · Cited by 3
Antioxidant enzyme dynamics suggest the absence of oxidative stress in the canine endometrium across the estrous cycle
Payan‐Carreira, R., Santos, C., & Santos, D. L. (2025) · Animal Reproduction Science · doi:10.1016/j.anireprosci.2025.107819 · Cited by 2
Salivary Zinc and Copper Levels Are Differentially Associated with ROS Levels in Breast Cancer Patients
Dyachenko, E. I., Sarf, E. A., & Bel’skaya, L. V. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26104784 · Cited by 2
Enzymatic and nonenzymatic antioxidant defense in plants under cold or chilling stress
Mazeed, A., Ansari, M. I., & NILOFER, N. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-26799-4.00001-3 · Cited by 2
Molecular delineation, immune modulation analysis, and antioxidant functional assessment of catalase (CAT) from chub mackerel (Scomber japonicus)
Dilshan, M. A. H., Omeka, W. K. M., Udayantha, H. M. V., Liyanage, D. S., Rodrigo, D. C. G., Ganepola, G. A. N. P., Harishchandra, H. P. U. M., Hanchapola, H. A. C. R., Kodagoda, Y. K., Kim, J., et al. (2025) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2025.105447 · Cited by 2
Photolysis of reactive species in plasma-activated water through combination treatment with ultraviolet light led to synergistic inactivation of foodborne pathogens
Jyung, S., & Kang, D. (2025) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2025.104348 · Cited by 2
Design and Synthesis of Caffeine-Based Derivatives with Antioxidant and Neuroprotective Activity: In Vitro Evaluation and SwissADME Profiling
Stefanova, D., Garip, A., Tzankova, V., Kostov, S., Mateev, E., Zlatkov, A., & Mitkov, Y. (2026) · Antioxidants · doi:10.3390/antiox15020217 · Cited by 2
HPV Infection and Oxidative Stress in Cervical Carcinogenesis: Linking Apoptosis, Senescence, SASP, and EMT
Despot, A., Fureš, R., Despot, A.-M., Hrgović, Z., Gredičak, M., Malojčić, S. M., Ćosić, V., Ðogić, L. M., Sinković, N., & Sabol, I. (2026) · Antioxidants · doi:10.3390/antiox15040486 · Cited by 3
Complementary in vitro and in vivo strategies to assess the biological effects of the nano enabled food additives E171 and E551
Peropadre, A., Vega-Cuesta, P., Freire, P. F., Pulido, D., Carrière, M., & de Celis, J. F. (2023) · Environmental Science Nano · doi:10.1039/d3en00009e · Cited by 2
Sub-Acute Toxicity Profile of Aqueous Leaf Extract of Pavetta crassipes (K. Schum) in Rats
Patrick, E. B., Otimenyin, S. O., & Bukar, B. B. (2023) · Tropical Journal of Natural Product Research · doi:10.26538/tjnpr/v7i5.25 · Cited by 2
Alzheimer’s Disease: An Attempt of Total Recall
Bolshakov, A. P., Gerasimov, K., & Dobryakova, Y. V. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-240620 · Cited by 2
Genetic Markers Associated with Ferroptosis in Cardiovascular Diseases
Fisher-Bautista, B., Fonseca‐Camarillo, G., & Cruz‐Gregorio, A. (2025) · Future Pharmacology · doi:10.3390/futurepharmacol5030037 · Cited by 3
Testing of yeast cells damage using hydrogen peroxide spiking and Pd-NPs-based electrodes and impact of oxidoreductase presence on electrochemical read-out
Koch, M., Katsen‐Globa, A., Zolotukhina, E. V., & Silina, Y. E. (2023) · Biochemical Engineering Journal · doi:10.1016/j.bej.2023.108908 · Cited by 2
Measurement of chemiluminescence induced by cytochrome c plus hydrogen peroxide to characterize the peroxidase activity of various wines and the Botrytis cinerea related quality of Aszú wines of Tokaj in Hungary
Sipka, S., Nagy, A., Nagy, J. A., Nokhoijav, E., Csősz, É., & Baráth, S. (2023) · European Food Research and Technology · doi:10.1007/s00217-023-04370-2 · Cited by 3
BIOLOGICAL ROLE OF REACTIVE OXYGEN SPECIES IN MITOCHONDRIA
Dikal, М. V., Ferenchuk, Y., Bilous, T., Kopchuk, T., Драчук, В. М., & Bilous, V. (2023) · Clinical anatomy and operative surgery · doi:10.24061/1727-0847.22.2.2023.24 · Cited by 2
Superoxidase Dismutases (Sods) in the European Eel: Gene Characterization, Expression Response to Temperature Combined with Hormonal Maturation and Possible Migratory ImplicationsPreprint
Morini, M., Ferrão, L., Blanes-García, M., Pérez, L., Asturiano, J. F., & Morini, M. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4576896 · Cited by 2
Effect of Bitter-leaf (Vernonia amygdalina) Flavored Non-alcoholic Wheat Beer (NAWB) on, Insulin and GLUT-2 expression in Pancreas of High fat diet/Streptozotocin (HFD/STZ) Induced Diabetic Wistar Rats
Akerele, G. P., Adedayo, B. C., Oboh, G., & Ogunsuyi, O. B. (2023) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-023-01216-2 · Cited by 1
Hydrogen Peroxide
Duca, G. G., & Travin, S. (2023) · Advances in chemical and materials engineering book series · doi:10.4018/978-1-6684-7198-2.ch003 · Cited by 1
The effects of submicron particles of metal oxides on the production of hydrogen peroxide and the activity of oxidative enzymes of Aspergillus niger and Penicillium chrysogenum
Аникина, Н. А., Baryshkov, R. V., Shishkin, A. Y., Smirnova, O. N., & Смирнов, В. Ф. (2024) · Микология и фитопатология · doi:10.31857/s0026364824020055 · Cited by 1
Utilizing the apical-out enteroids in vitro model to investigate intestinal glucose transport, barrier function, oxidative stress, and inflammatory responses in broiler chickens
Mann, P., Liu, J., Yu, L.-E., Wolfenden, R., & Li, Y. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1470009 · Cited by 2
Investigation of neuroprotective effects of newly synthesized benzimidazolium salt against neurotoxicity in differentiated SH-SY5Y neuronal cells
Yıldız, F. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.152255 · Cited by 1
Role of hydrogen peroxide preconditioning in mesenchymal stem cell-mediated heart regeneration: Molecular insights
Siraj, A., & Haneef, K. (2025) · World Journal of Cardiology · doi:10.4330/wjc.v17.i8.107437 · Cited by 1
Pathogens That Rewrite the Rules: Ascoviruses, Elegant Manipulators of Cell Death Pathways and Architects of the Extracellular Viral Paradigm
Rudd, S. R., Miranda, L. S., Asariah, S., Rodgers, C. S., Estrada, J. T., Alonzo, M. A., & Bideshi, D. K. (2025) · Pathogens · doi:10.3390/pathogens14111094 · Cited by 1
Utilizing redox and catalytic activity of click-chemistry engineered Prussian blue anchored carbon black composite for cancer biomarker and H2O2 detection
Anbalagan, A. C., Mankala, K., Sahu, A. K., & Sawant, S. N. (2025) · Microchemical Journal · doi:10.1016/j.microc.2025.116287 · Cited by 1
Lutein protects against oxidative stress-mediated dysregulation of cardiac Beclin-1/mTOR activities and other pathological sequalae in rats exposed to doxorubicin
Asiwe, J. N., Yovwin, G. D., Omatseye, S. A., Kokori, M., Akpotor, E., Fabulous, P. O., Adueniwoma, E. O., Joseph, S. O., Ogodo, B. O., Ogbebor, F. O., et al. (2025) · Nutrire · doi:10.1186/s41110-025-00391-x · Cited by 2
Hepatoprotective Effects and Antioxidant Properties of a Herbal Detoxifying Formula Against Chlorpyrifos-Induced Toxicity in Sprague-Dawley Rats
Kunnaja, P., Chansakaow, S., Taychaworaditsakul, W., Intatham, S., Jaijoy, K., Wittayapraparat, A., Yusuk, P., Suksathan, R., & Sireeratawong, S. (2025) · Biology · doi:10.3390/biology15010017 · Cited by 2
AAD-2004 through clearing H2O2 reduces astrocyte proliferation and promotes neural regeneration after spinal cord injury
Mi, X., Shan, K., Ye, X., & Cheng, R. (2025) · Scientific Reports · doi:10.1038/s41598-025-33322-x · Cited by 1
Combined cyclodextrins and porphyrinoid derivatives in drug delivery systems: Developments and perspectives
de Souza, J. F., Silvestri, S., Souza, P. R., Fajardo, A. R., & Iglesias, B. A. (2025) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2025.126544 · Cited by 1
Iron Phosphide Aerogel Applied as Nanozymes for Sensitive Colorimetric Detection of H 2 O 2
Feng, X., Fan, H., Miao, J., Li, G., & Gao, J. (2026) · Advanced Sustainable Systems · doi:10.1002/adsu.202501731 · Cited by 1
Effects of Supramolecular Interactions on E/Z ‐Isomerizations in Water and Their Importance for Biological Applications
Akbulut, D., Pölderl, G., & Næsborg, L. (2026) · Archiv der Pharmazie · doi:10.1002/ardp.70242 · Cited by 1
Making sense of subcellular H2O2 in mammals
Waldeck‐Weiermair, M., Covington, T. A., Pandey, A. K., & Michel, T. M. (2026) · Redox Biochemistry and Chemistry · doi:10.1016/j.rbc.2026.100080 · Cited by 1
Harnessing salt stress to drive the efficient and inexpensive bioproduction of a valuable thermotolerant biocatalyst (Mn-catalase) from cyanobacterial biomass
Chakravarty, D., Tewari, H., & Ballal, A. D. (2023) · Bioresource Technology Reports · doi:10.1016/j.biteb.2023.101535 · Cited by 1
Isolation and Screening of Proteolytic Bacteria from Rice-Fish Farming System Sediments
Riady, R. M., Fitriadi, R., Kasprijo, Ryandini, D., Palupi, M., Sukardi, P., Nurhafid, M., Ahmad, M., & Asaf, R. (2024) · International Journal of Design & Nature and Ecodynamics · doi:10.18280/ijdne.190310 · Cited by 1
Evaluating the Efficacy of Titanium Dioxide Nanoparticles in Combination with Commonly Used Bleaching Agents: An In Vitro Study
Vemareddy, R., Naidu, S., Korrai, B., Nagadevara, S., Battu, S., Jyotsnanjali, T., & Kavuri, S. (2024) · World Journal of Dentistry · doi:10.5005/jp-journals-10015-2422 · Cited by 1
Dynamics of Free Radical Oxidative Processes During the Latent Period of Experimental Metastasizing to the Liver
Frantsiyants, E. M., Surikova, E. I., Kaplieva, I. V., Neskubina, I. V., Shakaryan, E. G., Снежко, А. В., Bandovkina, V. A., Trepitaki, L. K., Pogorelova, Y. A., Nemashkalova, L. A., et al. (2024) · Ural Medical Journal · doi:10.52420/umj.23.5.89 · Cited by 1
Action of 3-Hydroxy-3-Methylglutaryl-CoA Reductase Inhibitors on ABCA-1 protein (ATP-Binding Cassette Transporter-1) in endothelial cells stimulated with uremic serum
Carmona, S. D. M., Jardim, D. P., Dalboni, M. A., Nakamichi, R., Kuniyoshi, M., Marrocos, M. S. M., Quinto, B. M. R., & Batista, M. C. (2025) · Lipids in Health and Disease · doi:10.1186/s12944-024-02420-6 · Cited by 1
Phytochemical Profiling, GC-MS Analysis, and Antioxidant Activity of Polar Solvent Extracts of Conoclinium coelestinum Leaves
Odeghe, O. B., Onobrudu, D. A., Orororo, O. C., Ikoya, S., Apitikori-Owumi, J. E., Egbune, E. O., Nwogueze, B. C., Ojugbeli, E. T., Agboola, O. E., Awhin, E. P., et al. (2025) · Tropical Journal of Natural Product Research · doi:10.26538/tjnpr/v9i7.48 · Cited by 1
The Ameliorative Effect Of Vitamin C Against Hematological , Biochemical , Oxidative And Immunosuppressive Effect Of Cadmium Chloride In Rats.
Risha, E., Abdelhamid, F., Elshopakey, G. E., & Fawzy, M. (2023) · Egyptian Journal of Veterinary Science · doi:10.21608/ejvs.2023.181316.1417
Heavy Metals (Cadmium and Arsenic) Bioaccumulation and Their Impact on Antioxidant Status in Liver and Kidney of Male Albino Rats
Sreedevi, C., Kesavulu, V., & Rani, A. U. (2022) · Journal of Environmental Science and Pollution Research · doi:10.30799/jespr.229.22080401
MANAGEMENT OF COATED TONGUE RESEMBLES PSEUDOMEMBRANOUS CANDIDIASIS IN A MULTIDRUG-THERAPY PATIENT
Santoso, A. W., Santo, A. N. T., & Setiadhi, R. (2024) · Dentino Jurnal Kedokteran Gigi · doi:10.20527/dentino.v9i1.18863
Engineering of effective redox enzymes by exploring enzyme fusions
Purwani, N. (2024) · doi:10.33612/diss.1015988121
Estimation of antioxidant enzymes in hemodialysis patients
Majeed, S. A., محمد, A. M. J. ع. ا., & Atbee, M. Y. N. A. (2024) · Egyptian Pharmaceutical Journal · doi:10.4103/epj.epj_308_23 · Cited by 1
Role of Reactive Oxygen Species in Carcinogenesis and Polyphenols as an Emerging Therapeutic Intervention
Das, A. R., & Giri, S. (2024) · Biochemistry · doi:10.5772/intechopen.1006076
Decoding Translational Control and Gene Expression
Takalloo, S. (2024) · Carleton University's Institutional Repository (MacOdrum Library, Carleton University) · doi:10.22215/etd/2024-16062
Побічні ефекти сучасних хімічних дезінфектантів та антисептиків. Частина 2. Неалергічна та алергічна дія внаслідок їх інгаляційного проникнення в організм
Брицун, В. М., Попова, І. В., Ковальова, С. О., & Петренко, Т. В. (2024) · Asthma and allergy · doi:10.31655/2307-3373-2024-3-62-70
Characterization of Combined Effects of Reactive Oxygen Metabolites, Complement System, and Antimicrobial Peptides In Vitro
Krenev, I. A., Egorova, E. V., Gorbunov, N., Kostevich, V. A., Av, S., Komlev, A. S., Zabrodskaya, Y. A., Валерьевна, Ш. О., & Николаевич, Б. М. (2025) · Russian Journal of Bioorganic Chemistry · doi:10.1134/s1068162025010996
Phytochemical Profiling and Assessment of Lannea Welwitschia in Mitigation of Cdcl2-Induced Biochemical and Reproductive Dysregulation: Modulatory Effects on Steroidogenic Enzymes (3β-Hsd, 17β-Hsd, Cyp19a1, Star) and in Vivo Mechanisms in Female RatsPreprint
Eko, O. W., Eteng, M. U., Iwara, I. A., Eteng, K. K., Arikpo, K. E., Ekam, V. S., Igile, G. O., & Eyong, E. U. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5220062
Advances in Microbial Enzymes in Processing and Applications in Textiles
Fasim, A., Vaishnavi, K. S., Maheshwari, R., Sriprada, G., Veena, S. M., & More, S. S. (2025) · Springer eBooks · doi:10.1007/978-981-96-4860-3_6
Multifunctional nanoprobe for near-infrared and magnetic resonance dual-modal amyloid-β imaging and oxidative stress monitoring in early stage of Alzheimer's disease
Yang, Y., Wang, C., Kong, J., Zhang, J., & Wong, M. S. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.165383
Wss1 and Ddi1 DNA-Protein crosslink repair proteases protect Saccharomyces cerevisiae and Candida albicans against oxidative stress
Sukted, J., Junsuntonpass, A., Homchan, A., Mongkolsuk, S., Pakotiprapha, D., & Matangkasombut, O. (2025) · Scientific Reports · doi:10.1038/s41598-025-12238-6
The Effect of Intravenous Oxyhydrogen Nanobubble on Chronic Kidney Disease: Case Series
Indrajani, O., Hernowo, A. T., Ekasari, C. P., Yudhanata, R., & Sumitro, S. B. (2025) · Clinical Therapeutics · doi:10.1016/j.clinthera.2025.06.018
Exploring the antioxidant efficacy of boldine: A natural compound with broad-spectrum activity
Maharani Jaganathan, K. S. (2025) · International Journal of Biosciences (IJB) · doi:10.12692/ijb/27.4.82-92
Insect-Spinach Waste Synergy: Enhancing Cyamopsis tetragonoloba under Copper Stress
Afrouz, M., Majd-Marani, S., Zahedian, H., Arabnejad, F., Alebrahim, M. T., Eftekhari, A., Azghani, P., & Tseng, T. (2025) · ACS Omega · doi:10.1021/acsomega.5c06841
Role of plant defense enzymes, H2O2 and phenolics in resistance of cabbage cultivars to Plutella xylostella (L.)
Karmakar, P., Pal, S., & Chakraborty, G. (2025) · Journal of Plant Diseases and Protection · doi:10.1007/s41348-025-01178-y
Ameliorating Effect of Guaiacum officinale Mother Tincture on Adjuvant-Induced Arthritis Model by Modulating Oxidative Stress and Inflammation
Nisha, M., Sreelatha, S., Ratheesh, M., Sreevallabhan, S., Jose, S. P., Vijayan., T., & George, S. M. (2025) · Journal of Natural Remedies · doi:10.18311/jnr/2025/46425
Integrative Toxicology Profiling of Thuja sutchuenensis Essential Oil: From LD50 Safety Assessment to Hepatic Apoptosis and Gut Microbiota Modulation
Long, N., Zuo, Y., Yao, R., Yang, Q., Li, J., Zhang, X., You, S., Yang, P., & Deng, H. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.71296
Additional file 1 of MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation
Santiago, M. J., Chinnapaiyan, S., Panda, K., Rahman, M. S., Ghorai, S., Lucas, J. H., Black, S. M., Rahman, I., & Unwalla, H. J. (2024) · Figshare · doi:10.6084/m9.figshare.26860615
Additional file 7 of MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation
Santiago, M. J., Chinnapaiyan, S., Panda, K., Rahman, M. S., Ghorai, S., Lucas, J. H., Black, S. M., Rahman, I., & Unwalla, H. J. (2024) · Figshare · doi:10.6084/m9.figshare.26943498
Additional file 3 of MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation
Santiago, M. J., Chinnapaiyan, S., Panda, K., Rahman, M. S., Ghorai, S., Lucas, J. H., Black, S. M., Rahman, I., & Unwalla, H. J. (2024) · Figshare · doi:10.6084/m9.figshare.26943486
Additional file 2 of MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation
Santiago, M. J., Chinnapaiyan, S., Panda, K., Rahman, M. S., Ghorai, S., Lucas, J. H., Black, S. M., Rahman, I., & Unwalla, H. J. (2024) · Figshare · doi:10.6084/m9.figshare.26860676
Additional file 6 of MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation
Santiago, M. J., Chinnapaiyan, S., Panda, K., Rahman, M. S., Ghorai, S., Lucas, J. H., Black, S. M., Rahman, I., & Unwalla, H. J. (2024) · Figshare · doi:10.6084/m9.figshare.26943495
Additional file 5 of MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation
Santiago, M. J., Chinnapaiyan, S., Panda, K., Rahman, M. S., Ghorai, S., Lucas, J. H., Black, S. M., Rahman, I., & Unwalla, H. J. (2024) · Figshare · doi:10.6084/m9.figshare.26943492
Additional file 4 of MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation
Santiago, M. J., Chinnapaiyan, S., Panda, K., Rahman, M. S., Ghorai, S., Lucas, J. H., Black, S. M., Rahman, I., & Unwalla, H. J. (2024) · Figshare · doi:10.6084/m9.figshare.26943489
Additional file 8 of MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation
Santiago, M. J., Chinnapaiyan, S., Panda, K., Rahman, M. S., Ghorai, S., Lucas, J. H., Black, S. M., Rahman, I., & Unwalla, H. J. (2024) · Figshare · doi:10.6084/m9.figshare.26943501
L-tyrosine-stabilized silver nanoparticles for colorimetric detection of hydrogen peroxide
Shekhovtsov, N. V., Sych, T. S., Buglak, A. A., & Kononov, A. I. (2026) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2026.127631
Oxygen Free Radicals and Cancer: Protective Role of Endogenous Antioxidants and Natural Compounds
Irfan, Z., Firdous, S. M., Giri, S., & Hashmi, A. (2026) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/0118715206459486260128064009
Luminescent Transition Metal Complexes for Biological Sensing and Labelling
Morales-Pioz, E., Benedi, A., & Fernández‐Moreira, V. (2026) · Royal Society of Chemistry eBooks · doi:10.1039/9781837677061-00108
Differential Oxidative Susceptibility Between Metabolically Healthy and Unhealthy Obesity
Khadra, K. M. A., Bataineh, M. I., Abu-Khadra, R. K., & Saleh, J. (2026) · Biomedical & Pharmacology Journal · doi:10.13005/bpj/3364
Management of the antioxidant response of the hyperaccumulator plant Noccaea caerulescens to abiotic stress
Sherri, M. C. (2023) · theses.fr (ABES) · doi:10.70675/76aade76z590cz4e03z9407z1e7b0bfbd4b4

Authors: Andrés, C. M. C., Pérez de la Lastra, J. M., Juan, C. A., Plou, F. J., & Pérez-Lebeña, E.
Affiliations: Hospital Clínico Universitario de Valladolid (ES)
Institute of Natural Products and Agrobiology, CSIC-Spanish Research Council, Avda. Astrofísico Fco. Sánchez, 3, 38206 La Laguna, Spain
Cinquima Institute and Department of Organic Chemistry, Faculty of Sciences, Valladolid University, Paseo de Belén, 7, 47011 Valladolid, Spain
Consejo Superior de Investigaciones Científicas (ES)
Sistemas de Biotecnología y Recursos Naturales, 47625 Valladolid, Spain
ORCID: Andrés, Celia María Curieses
Pérez de la Lastra, José Manuel
Plou, Francisco J.
Venue: Stresses
Publisher: MDPI AG
Published: 2022-07-25
Volume: 2
Issue: 3
Pages: 256-274
ISSN: 2673-7140 (ISSN-L)
DOI: 10.3390/stresses2030019
OpenAlex: W4287879577
Cited by: 218
References: 107
Citations by year: 2026: 29 · 2025: 65 · 2024: 68 · 2023: 51 · 2022: 5
FWCI: 15.44
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Stresses (publishedVersion, cc-by)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: Junta de Castilla y León (FEDER-VA115P17, VA149G18, ProID2020010134, 2019SP43, PID2019-105838RB-C31)
European Funds for Regional Development-FEDER (FEDER-VA115P17, VA149G18, ProID2020010134, 2019SP43, PID2019-105838RB-C31)
Caja Canarias (FEDER-VA115P17, VA149G18, ProID2020010134, 2019SP43, PID2019-105838RB-C31)
Spanish Ministry of Economy and Competitiveness (FEDER-VA115P17, VA149G18, ProID2020010134, 2019SP43, PID2019-105838RB-C31)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cancer and biochemical research
Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
Keywords: hydrogen peroxide, redox signaling, hydrogen sulfide, nitric oxide, apoptosis, inflammation, oxidative stress, bioenergetic failure, enzymatic pathways, mammalian cells, pathology

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Chemistry of Hydrogen Peroxide Formation and Elimination in Mammalian Cells, and Its Role in Various Pathologies

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks