Viral and host factors regulating HIV-1 envelope protein trafficking and particle incorporation

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

Ke, Z., Otón, J., Qu, K., Cortese, M., Žíla, V., McKeane, L., Nakane, T., Zivanov, J., Neufeldt, C. J., Cerikan, B., et al. (2020) · Nature · doi:10.1038/s41586-020-2665-2 · Cited by 1,113 · see citing works

Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.

Leonard, C. K., Spellman, M. W., Riddle, L. M., Harris, R. J., Thomas, J. N., & Gregory, T. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)86956-3 · Cited by 986 · see citing works

Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

Jacks, T., Power, M. D., Masiarz, F. R., Luciw, P. A., Barr, P. J., & Varmus, H. E. (1988) · Nature · doi:10.1038/331280a0 · Cited by 966 · see citing works

Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1

Göttlinger, H. G., Sodroski, J. G., & Haseltine, W. A. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.15.5781 · Cited by 841 · see citing works

Distribution and three-dimensional structure of AIDS virus envelope spikes

Zhu, P., Liu, J., Bess, J. W., Chertova, E. N., Lifson, J. D., Grisé, H., Ofek, G., Taylor, K. A., & Roux, K. H. (2006) · Nature · doi:10.1038/nature04817 · Cited by 776 · see citing works

Myristoylation-dependent replication and assembly of human immunodeficiency virus 1.

Bryant, M. L., & Ratner, L. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.2.523 · Cited by 624 · see citing works

Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus

McCune, J. M., Rabin, L. B., Feinberg, M. B., Lieberman, M., Kosek, J. C., Reyes, G. R., & Weissman, I. L. (1988) · Cell · doi:10.1016/0092-8674(88)90487-4 · Cited by 610 · see citing works

Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gpl60

Hallenberger, S., Bosch, V., Angliker, H., Shaw, E., Klenk, H.-D., & Garten, W. (1992) · Nature · doi:10.1038/360358a0 · Cited by 582 · see citing works

Virus budding and the ESCRT pathway

Votteler, J., & Sundquist, W. I. (2013) · Cell Host & Microbe · doi:10.1016/j.chom.2013.08.012 · Cited by 547 · see citing works

Infectious HIV-1 assembles in late endosomes in primary macrophages

Pelchen–Matthews, A., Kramer, B., & Marsh, M. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200304008 · Cited by 491 · see citing works

HIV-1 Envelope Glycoprotein Biosynthesis, Trafficking, and Incorporation

Checkley, M. A., Luttge, B. G., & Freed, E. O. (2011) · Journal of Molecular Biology · doi:10.1016/j.jmb.2011.04.042 · Cited by 477 · see citing works

The retromer complex – endosomal protein recycling and beyond

Seaman, M. N. J. (2012) · Journal of Cell Science · doi:10.1242/jcs.103440 · Cited by 455 · see citing works

Lipid composition and fluidity of the human immunodeficiency virus envelope and host cell plasma membranes.

Aloia, R. C., Tian, H., & Jensen, F. C. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.11.5181 · Cited by 443 · see citing works

Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions

Zhu, P., Chertova, E., Bess, J., Lifson, J. D., Arthur, L. O., Liu, J., Taylor, K. A., & Roux, K. H. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2634931100 · Cited by 431 · see citing works

Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160

Willey, R. L., Bonifacino, J. S., Potts, B. J., Martin, M. A., & Klausner, R. D. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.24.9580 · Cited by 428 · see citing works

Domains of the human immunodeficiency virus type 1 matrix and gp41 cytoplasmic tail required for envelope incorporation into virions

Freed, E., & Martin, M. (1996) · Journal of Virology · doi:10.1128/jvi.70.1.341-351.1996 · Cited by 382 · see citing works

Virion incorporation of envelope glycoproteins with long but not short cytoplasmic tails is blocked by specific, single amino acid substitutions in the human immunodeficiency virus type 1 matrix

Freed, E., & Martin, M. (1995) · Journal of Virology · doi:10.1128/jvi.69.3.1984-1989.1995 · Cited by 344 · see citing works

In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53

Deneka, M., Pelchen–Matthews, A., Byland, R., Ruíz-Mateos, E., & Marsh, M. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200609050 · Cited by 340 · see citing works

Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein

Earl, P. L., Moss, B. A., & Doms, R. W. (1991) · Journal of Virology · doi:10.1128/jvi.65.4.2047-2055.1991 · Cited by 338 · see citing works

The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions

Yu, X., Yuan, X., Matsuda, Z., Lee, T. H., & Essex, M. (1992) · Journal of Virology · doi:10.1128/jvi.66.8.4966-4971.1992 · Cited by 319 · see citing works

Orchestration of cell surface proteins by Rab11

Welz, T., Wellbourne-Wood, J., & Kerkhoff, E. (2014) · Trends in Cell Biology · doi:10.1016/j.tcb.2014.02.004 · Cited by 317 · see citing works

Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1

Pinter, A., Honnen, W. J., TILLEY, S. A., Bona, C. A., Zaghouani, H., Górny, M. K., & Zolla‐Pazner, S. (1989) · Journal of Virology · doi:10.1128/jvi.63.6.2674-2679.1989 · Cited by 291 · see citing works

Envelope Glycoprotein Incorporation, Not Shedding of Surface Envelope Glycoprotein (gp120/SU), Is the Primary Determinant of SU Content of Purified Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus

Chertova, E. N., Julian W. Bess, Crise, B. J., Sowder, R. C., Schaden, T. M., Hilburn, J. M., Hoxie, J. A., Benveniste, R. Ė., Lifson, J. D., Henderson, L. E., et al. (2002) · Journal of Virology · doi:10.1128/jvi.76.11.5315-5325.2002 · Cited by 289 · see citing works

Role of the matrix protein in the virion association of the human immunodeficiency virus type 1 envelope glycoprotein

Dorfman, T., Mammano, F., Haseltine, W. A., & Göttlinger, H. G. (1994) · Journal of Virology · doi:10.1128/jvi.68.3.1689-1696.1994 · Cited by 288 · see citing works

Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides

Chan, R., Uchil, P. D., Jin, J., Shui, G., Ott, D. E., Mothes, W., & Wenk, M. R. (2008) · Journal of Virology · doi:10.1128/jvi.00981-08 · Cited by 282 · see citing works

Few and Far Between: How HIV May Be Evading Antibody Avidity

Klein, J. S., & Björkman, P. J. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1000908 · Cited by 272 · see citing works

Guanylate Binding Protein (GBP) 5 Is an Interferon-Inducible Inhibitor of HIV-1 Infectivity

Krapp, C., Hotter, D., Gawanbacht, A., McLaren, P. J., Kluge, S. F., Stürzel, C. M., Mack, K., Reith, E., Engelhart, S., Ciuffi, A., et al. (2016) · Cell Host & Microbe · doi:10.1016/j.chom.2016.02.019 · Cited by 256 · see citing works

The long cytoplasmic tail of gp41 is required in a cell type-dependent manner for HIV-1 envelope glycoprotein incorporation into virions

Murakami, T., & Freed, E. O. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.1.343 · Cited by 252 · see citing works

Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs

Schwartz, S., Felber, B. K., Fenyö, E. M., & Pavlakis, G. N. (1990) · Journal of Virology · doi:10.1128/jvi.64.11.5448-5456.1990 · Cited by 248 · see citing works

Adaptor proteins involved in polarized sorting

Bonifacino, J. S. (2014) · The Journal of Cell Biology · doi:10.1083/jcb.201310021 · Cited by 247 · see citing works

Distribution and Function of Ap-1 Clathrin Adaptor Complexes in Polarized Epithelial Cells

Fölsch, H., Pypaert, M., Schu, P. V., & Mellman, I. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.3.595 · Cited by 243 · see citing works

A conformational switch controlling HIV‐1 morphogenesis

Gross, I., Hohenberg, H., Wilk, T., Wiegers, K. J., Grättinger, M., Müller, B., Fuller, S., & Kräusslich, H. (2000) · The EMBO Journal · doi:10.1093/emboj/19.1.103 · Cited by 241 · see citing works

Cryo-Electron Tomographic Structure of an Immunodeficiency Virus Envelope Complex In Situ

Zanetti, G., Briggs, J. A. G., Grünewald, K., Sattentau, Q. J., & Fuller, S. D. (2006) · PLoS Pathogens · doi:10.1371/journal.ppat.0020083 · Cited by 232 · see citing works

Coupling of Human Immunodeficiency Virus Type 1 Fusion to Virion Maturation: a Novel Role of the gp41 Cytoplasmic Tail

Wyma, D. J., Jiang, J., Shi, J., Zhou, J., Lineberger, J. E., Miller, M. D., & Aiken, C. (2004) · Journal of Virology · doi:10.1128/jvi.78.7.3429-3435.2004 · Cited by 225 · see citing works

Genetic Evidence for an Interaction between Human Immunodeficiency Virus Type 1 Matrix and α-Helix 2 of the gp41 Cytoplasmic Tail

Murakami, T., & Freed, E. O. (2000) · Journal of Virology · doi:10.1128/jvi.74.8.3548-3554.2000 · Cited by 214 · see citing works

Direct interaction between the envelope and matrix proteins of HIV-1

Cosson, P. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00964.x · Cited by 211 · see citing works

A Membrane-proximal Tyrosine-based Signal Mediates Internalization of the HIV-1 Envelope Glycoprotein via Interaction with the AP-2 Clathrin Adaptor*

Böge, M., Wyss, S., Bonifacino, J., & Thali, M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.25.15773 · Cited by 210 · see citing works

The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains

Fölsch, H., Pypaert, M., Maday, S., Pelletier, L., & Mellman, I. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200309020 · Cited by 206 · see citing works

Interaction of Endocytic Signals from the HIV-1 Envelope Glycoprotein Complex with Members of the Adaptor Medium Chain Family

Ohno, H., Aguilar, R. C., Fournier, M.-C., Hennecke, S., Cosson, P., & Bonifacino, J. S. (1997) · Virology · doi:10.1006/viro.1997.8839 · Cited by 195 · see citing works

Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and role in processing for association with class II MHC

Rowell, J. F., Stanhope, P. E., & Siliciano, R. F. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.1.473 · Cited by 191 · see citing works

Interactions of the Cytoplasmic Domains of Human and Simian Retroviral Transmembrane Proteins with Components of the Clathrin Adaptor Complexes Modulate Intracellular and Cell Surface Expression of Envelope Glycoproteins

Berlioz‐Torrent, C., Shacklett, B. L., Erdtmann, L., Delamarre, L., Bouchaert, I., Sonigo, P., Dokhélar, M., & Bénarous, R. (1999) · Journal of Virology · doi:10.1128/jvi.73.2.1350-1361.1999 · Cited by 191 · see citing works

The membrane‐proximal intracytoplasmic tyrosine residue of HIV‐1 envelope glycoprotein is critical for basolateral targeting of viral budding in MDCK cells

Lodge, R., Lalonde, J., Lemay, G., & Cohen, É. A. (1997) · The EMBO Journal · doi:10.1093/emboj/16.4.695 · Cited by 186 · see citing works

Evidence for a Stable Interaction of gp41 with Pr55Gag in Immature Human Immunodeficiency Virus Type 1 Particles

Wyma, D. J., Kotov, A., & Aiken, C. (2000) · Journal of Virology · doi:10.1128/jvi.74.20.9381-9387.2000 · Cited by 182 · see citing works

Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins

Braun, E., Hotter, D., Koepke, L., Zech, F., Groß, R. M., Sparrer, K. M. J., Müller, J. A., Pfaller, C. K., Heusinger, E., Wombacher, R., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.04.063 · Cited by 179 · see citing works

Antiserum to a Synthetic Peptide Recognizes the HTLV-III Envelope Glycoprotein

Kennedy, R. C., Henkel, R. D., Pauletti, D., Allan, J. D., Lee, T. H., Essex, M., & Dreesman, G. R. (1986) · Science · doi:10.1126/science.3006246 · Cited by 174 · see citing works

The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells

Lodge, R., Göttlinger, H., Gabuzda, D., Cohen, É., & Lemay, G. (1994) · Journal of Virology · doi:10.1128/jvi.68.8.4857-4861.1994 · Cited by 172 · see citing works

Regulation of Human Immunodeficiency Virus Type 1 Env-Mediated Membrane Fusion by Viral Protease Activity

Murakami, T., Ablan, S. D., Freed, E. O., & Tanaka, Y. (2003) · Journal of Virology · doi:10.1128/jvi.78.2.1026-1031.2004 · Cited by 172 · see citing works

Studies with crosslinking reagents on the oligomeric structure of the env glycoprotein of HIV

Schawaller, M., Smith, G., Skehel, J. J., & Wiley, D. C. (1989) · Virology · doi:10.1016/0042-6822(89)90142-6 · Cited by 160 · see citing works

Retained in vitro infectivity and cytopathogenicity of HIV-1 despite truncation of the C-terminal tail of the env gene product

Wilk, T., Pfeiffer, T., & Bosch, V. (1992) · Virology · doi:10.1016/0042-6822(92)90692-i · Cited by 155 · see citing works

The EGFR odyssey – from activation to destruction in space and time

Bakker, J., Spits, M., Neefjes, J., & Berlin, I. (2017) · Journal of Cell Science · doi:10.1242/jcs.209197 · Cited by 152 · see citing works

The Highly Conserved C-Terminal Dileucine Motif in the Cytosolic Domain of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Is Critical for Its Association with the AP-1 Clathrin Adapter

Wyss, S., Berlioz‐Torrent, C., Boge, M., Blot, G., Höning, S., Bénarous, R., & Thali, M. (2001) · Journal of Virology · doi:10.1128/jvi.75.6.2982-2992.2001 · Cited by 149 · see citing works

The Clathrin Adaptor AP-1A Mediates Basolateral Polarity

Gravotta, D., Carvajal-Gonzalez, J. M., Mattera, R., Deborde, S., Banfelder, J. R., Bonifacino, J. S., & Rodriguez-Boulan, E. (2012) · Developmental Cell · doi:10.1016/j.devcel.2012.02.004 · Cited by 148 · see citing works

Tail-interacting protein TIP47 is a connector between Gag and Env and is required for Env incorporation into HIV-1 virions

López‐Vergès, S., Camus, G., Blot, G., Beauvoir, R., Bénarous, R., & Berlioz‐Torrent, C. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602941103 · Cited by 147 · see citing works

An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface.

Sauter, M. M., Pelchen–Matthews, A., Bron, R., Marsh, M., LaBranche, C. C., Vance, P. J., Romano, J., Haggarty, B., Hart, T. K., Lee, W. M., et al. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.132.5.795 · Cited by 146 · see citing works

A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells

Labranche, C. C., Sauter, M. M., Haggarty, B., Vance, P., Romano, J., Hart, T. K., Bugelski, P. J., Marsh, M., & Hoxie, J. (1995) · Journal of Virology · doi:10.1128/jvi.69.9.5217-5227.1995 · Cited by 143 · see citing works

HIV-1 Buds and Accumulates in “Nonacidic” Endosomes of Macrophages

Jouve, M. J., Sol‐Foulon, N., Watson, S., Schwartz, O., & Benaroch, P. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2007.06.011 · Cited by 141 · see citing works

Calreticulin Interacts with Newly Synthesized Human Immunodeficiency Virus Type 1 Envelope Glycoprotein, Suggesting a Chaperone Function Similar to That of Calnexin

Otteken, A., & Moss, B. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.1.97 · Cited by 136 · see citing works

A Conserved Dileucine Motif Mediates Clathrin and AP-2–dependent Endocytosis of the HIV-1 Envelope Protein

Byland, R., Vance, P. J., Hoxie, J. A., & Marsh, M. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-06-0535 · Cited by 134 · see citing works

Human immunodeficiency virus type 1 envelope protein endocytosis mediated by a highly conserved intrinsic internalization signal in the cytoplasmic domain of gp41 is suppressed in the presence of the Pr55gag precursor protein

Egan, M. A., Carruth, L. M., Rowell, J. F., Yu, X., & Siliciano, R. F. (1996) · Journal of Virology · doi:10.1128/jvi.70.10.6547-6556.1996 · Cited by 131 · see citing works

Recurrent Signature Patterns in HIV-1 B Clade Envelope Glycoproteins Associated with either Early or Chronic Infections

Gnanakaran, S., Tanmoy Bhattacharya, A., Daniels, M., Keele, B. F., Hraber, P., Lapedes, A. S., Shen, T., Gaschen, B. K., Krishnamoorthy, M., Li, H.-H., et al. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002209 · Cited by 128 · see citing works

Targeting of the Human Immunodeficiency Virus Type 1 Envelope to thetrans-Golgi Network through Binding to TIP47 Is Required for Env Incorporation into Virions and Infectivity

Blot, G., Janvier, K., Panse, S. L., Bénarous, R., & Berlioz‐Torrent, C. (2003) · Journal of Virology · doi:10.1128/jvi.77.12.6931-6945.2003 · Cited by 128 · see citing works

Mechanism of Translation of Monocistronic and Multicistronic Human Immunodeficiency Virus Type 1 mRNAs

Schwartz, S., Felber, B. K., & Pavlakis, G. N. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.1.207 · Cited by 127 · see citing works

Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies

Pritchard, L. K., Spencer, D. I. R., Royle, L., Bonomelli, C., Seabright, G. E., Behrens, A., Kulp, D. W., Menis, S., Krumm, S. A., Dunlop, D. C., et al. (2015) · Nature Communications · doi:10.1038/ncomms8479 · Cited by 125 · see citing works

The Tale of the Long Tail: the Cytoplasmic Domain of HIV-1 gp41

Postler, T. S., & Desrosiers, R. C. (2012) · Journal of Virology · doi:10.1128/jvi.02053-12 · Cited by 122 · see citing works

Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1

Hammonds, J. E., Beeman, N., Ding, L., Takushi, S., Francis, A. C., Wang, J.-J., Melikyan, G. B., & Spearman, P. (2017) · PLOS Pathogens · doi:10.1371/journal.ppat.1006181 · Cited by 110 · see citing works

Lentivirus genomic organization: The complete nucleotide sequence of the env gene region of equine infectious anemia virus

Rushlow, K. E., Olsen, K., Stiegler, G. L., Payne, S., Montelaro, R. C., & Issel, C. J. (1986) · Virology · doi:10.1016/0042-6822(86)90195-9 · Cited by 108 · see citing works

An amphipathic peptide from the C-terminal region of the human immunodeficiency virus envelope glycoprotein causes pore formation in membranes

Chernomordik, L., Chanturiya, A., Suss-Toby, E., Nora, E., & Zimmerberg, J. J. (1994) · Journal of Virology · doi:10.1128/jvi.68.11.7115-7123.1994 · Cited by 107 · see citing works

Rab11-FIP1C and Rab14 Direct Plasma Membrane Sorting and Particle Incorporation of the HIV-1 Envelope Glycoprotein Complex

Qi, M., Williams, J. A., Chu, H., Chen, X., Wang, J.-J., Ding, L., Akhirome, E., Wen, X., Lapierre, L. A., Goldenring, J. R., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003278 · Cited by 106 · see citing works

Dimeric RNA Recognition Regulates HIV-1 Genome Packaging

Nikolaitchik, O. A., Dilley, K. A., Fu, W., Gorelick, R. J., Tai, S.-H. S., Soheilian, F., Ptak, R. G., Nagashima, K., Pathak, V. K., & Hu, W.-S. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003249 · Cited by 106 · see citing works

Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis

Giridharan, S. S. P., Cai, B., Vitale, N., Naslavsky, N., & Caplan, S. (2013) · Molecular Biology of the Cell · doi:10.1091/mbc.e13-01-0026 · Cited by 105 · see citing works

Membrane interactions of synthetic peptides corresponding to amphipathic helical segments of the human immunodeficiency virus type-1 envelope glycoprotein.

Srinivas, S., Srinivas, R. V., Anantharamaiah, G. M., Segrest, J. P., & Compans, R. W. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50546-4 · Cited by 104 · see citing works

Maturation of the matrix and viral membrane of HIV-1

Qu, K., Ke, Z., Žíla, V., Anders‐Össwein, M., Glass, B., Muecksch, F., Müller, R., Schultz, C., Müller, B., Kräusslich, H., et al. (2021) · Science · doi:10.1126/science.abe6821 · Cited by 103 · see citing works

Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum

Land, A., & Braakman, I. (2001) · Biochimie · doi:10.1016/s0300-9084(01)01314-1 · Cited by 97 · see citing works

RNA Packaging in HIV

Rein, A. R. (2019) · Trends in Microbiology · doi:10.1016/j.tim.2019.04.003 · Cited by 96 · see citing works

Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses

McLaren, P. J., Gawanbacht, A., Pyndiah, N., Krapp, C., Hotter, D., Kluge, S. F., Götz, N., Heilmann, J., Mack, K., Sauter, D., et al. (2015) · Retrovirology · doi:10.1186/s12977-015-0165-5 · Cited by 91 · see citing works

Global site-specific analysis of glycoprotein N-glycan processing

Cao, L., Diedrich, J. K., Ma, Y., Wang, N., Pauthner, M. G., Park, S.-K. R., Delahunty, C. M., McLellan, J. S., Burton, D. R., Yates, J. R., et al. (2018) · Nature Protocols · doi:10.1038/nprot.2018.024 · Cited by 91 · see citing works

Cryo-ET of Env on intact HIV virions reveals structural variation and positioning on the Gag lattice

Prasad, V. M., Leaman, D. P., Lovendahl, K. N., Croft, J. T., Benhaim, M. A., Hodge, E. A., Zwick, M. B., & Lee, K. K. (2022) · Cell · doi:10.1016/j.cell.2022.01.013 · Cited by 91 · see citing works

Tetherin/BST-2 Is Essential for the Formation of the Intracellular Virus-Containing Compartment in HIV-Infected Macrophages

Chu, H., Wang, J.-J., Qi, M., Yoon, J.-J., Chen, X., Wen, X., Hammonds, J. E., Ding, L., & Spearman, P. W. (2012) · Cell Host & Microbe · doi:10.1016/j.chom.2012.07.011 · Cited by 85 · see citing works

Molecular Architecture of the Cleavage-Dependent Mannose Patch on a Soluble HIV-1 Envelope Glycoprotein Trimer

Behrens, A., Harvey, D. J., Milne, E., Cupo, A., Kumar, A., Zitzmann, N., Struwe, W. B., Moore, J. P., & Crispin, M. (2016) · Journal of Virology · doi:10.1128/jvi.01894-16 · Cited by 81 · see citing works

The impact of envelope glycoprotein cleavage on the antigenicity, infectivity, and neutralization sensitivity of Env-pseudotyped human immunodeficiency virus type 1 particles

Herrera, C., Klasse, P. J., Michael, E., Kake, S., Barnes, K., Kibler, C. W., Campbell-Gardener, L., Si, Z., Sodroski, J., Moore, J. P., et al. (2005) · Virology · doi:10.1016/j.virol.2005.05.002 · Cited by 78 · see citing works

Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein

Piai, A., Fu, Q., Cai, Y., Ghantous, F., Xiao, T., Shaik, M. M., Peng, H., Rits‐Volloch, S., Chen, W., Seaman, M. S., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16165-0 · Cited by 78 · see citing works

Biochemical evidence of a role for matrix trimerization in HIV-1 envelope glycoprotein incorporation

Tedbury, P. R., Novikova, M., Ablan, S. D., & Freed, E. O. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1516618113 · Cited by 77 · see citing works

Maturation-Dependent Human Immunodeficiency Virus Type 1 Particle Fusion Requires a Carboxyl-Terminal Region of the gp41 Cytoplasmic Tail

Jiang, J., & Aiken, C. (2007) · Journal of Virology · doi:10.1128/jvi.00592-07 · Cited by 74 · see citing works

Structure of the Ebola virus glycoprotein spike within the virion envelope at 11 Å resolution

Beniac, D. R., & Booth, T. F. (2017) · Scientific Reports · doi:10.1038/srep46374 · Cited by 74 · see citing works

Regulation of Virus Release by the Macrophage-Tropic Human Immunodeficiency Virus Type 1 AD8 Isolate Is Redundant and Can Be Controlled by either Vpu or Env

Schubert, U., Bour, S. P., Willey, R. L., & Strebel, K. (1999) · Journal of Virology · doi:10.1128/jvi.73.2.887-896.1999 · Cited by 73 · see citing works

A Leucine Zipper-Like Sequence from the Cytoplasmic Tail of the HIV-1 Envelope Glycoprotein Binds and Perturbs Lipid Bilayers

Kliger, Y., & Shai, Y. (1997) · Biochemistry · doi:10.1021/bi962935r · Cited by 69 · see citing works

Identification of Two Sequences in the Cytoplasmic Tail of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein That Inhibit Cell Surface Expression

Bültmann, A., Muranyi, W., Seed, B., & Haas, J. (2001) · Journal of Virology · doi:10.1128/jvi.75.11.5263-5276.2001 · Cited by 68 · see citing works

Identification of the Cellular Prohibitin 1/Prohibitin 2 Heterodimer as an Interaction Partner of the C-Terminal Cytoplasmic Domain of the HIV-1 Glycoprotein

Emerson, V., Holtkotte, D., Pfeiffer, T., Wang, I.-H., Schnölzer, M., Kempf, T., & Bosch, V. (2009) · Journal of Virology · doi:10.1128/jvi.01641-09 · Cited by 67 · see citing works

Interaction of peptide fragment 828-848 of the envelope glycoprotein of human immunodeficiency virus type I with lipid bilayers

Gawrisch, K., Han, K.-H., Yang, J. S., Bergelson, L. D., & Ferretti, J. A. (1993) · Biochemistry · doi:10.1021/bi00063a024 · Cited by 67 · see citing works

Deletion of the vpu Sequences prior to the env in a Simian–Human Immunodeficiency Virus Results in Enhanced Env Precursor Synthesis but Is Less Pathogenic for Pig-Tailed Macaques

Stephens, E. B., McCormick, C., Pacyniak, E., Griffin, D. M., Pinson, D. M., Sun, F., Nothnick, W. B., Wong, S. W., Gunderson, R. S., Berman, N. E. J., et al. (2002) · Virology · doi:10.1006/viro.2001.1244 · Cited by 65 · see citing works

Retromer Regulates HIV-1 Envelope Glycoprotein Trafficking and Incorporation into Virions

Groppelli, E., Len, A. C. L., Granger, L. A., & Jolly, C. L. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004518 · Cited by 64 · see citing works

HIV-1 Replication and the Cellular Eukaryotic Translation Apparatus

Guerrero, S. X., Batisse, J., Libre, C., Bernacchi, S., Marquet, R., & Paillart, J. (2015) · Viruses · doi:10.3390/v7010199 · Cited by 61 · see citing works

A Signature in HIV-1 Envelope Leader Peptide Associated with Transition from Acute to Chronic Infection Impacts Envelope Processing and Infectivity

Asmal, M., Hellmann, I., Liu, W., Keele, B. F., Perelson, A. S., Tanmoy Bhattacharya, A., Gnanakaran, S., Daniels, M., Haynes, B. F., Korber, B., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023673 · Cited by 58 · see citing works

Use of a resin-bound synthetic peptide for identifying a neutralizing antigenic determinant associated with the human immunodeficiency virus envelope.

Kennedy, R. C., Dreesman, G. R., Chanh, T. C., Boswell, R. N., Allan, J. D., Lee, T. H., Essex, M., Sparrow, J. T., Ho, D. D., & Kanda, P. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)45641-4 · Cited by 58 · see citing works

Solution Structure and Membrane Interaction of the Cytoplasmic Tail of HIV-1 gp41 Protein

Murphy, R., Samal, A., Vlach, J., & Saad, J. (2017) · Structure · doi:10.1016/j.str.2017.09.010 · Cited by 53 · see citing works

Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120

Yolitz, J., Schwing, C., Chang, J., Ryk, D. V., Nawaz, F., Wei, D., Cicala, C., Arthos, J. A., & Fauci, A. S. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1722627115 · Cited by 53 · see citing works

Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity

Bhakta, S. J., Shang, L., Prince, J. L., Claiborne, D. T., & Hunter, E. (2011) · Retrovirology · doi:10.1186/1742-4690-8-37 · Cited by 51 · see citing works

HIV-1 Envelope Glycoprotein Trafficking through the Endosomal Recycling Compartment Is Required for Particle Incorporation

Kirschman, J., Qi, M., Ding, L., Hammonds, J. E., Dienger-Stambaugh, K., Wang, J.-J., Lapierre, L. A., Goldenring, J. R., & Spearman, P. W. (2017) · Journal of Virology · doi:10.1128/jvi.01893-17 · Cited by 51 · see citing works

A tyrosine-based motif in the HIV-1 envelope glycoprotein tail mediates cell-type– and Rab11-FIP1C–dependent incorporation into virions

Qi, M., Chu, H., Chen, X., Choi, J., Wen, X., Hammonds, J. E., Ding, L., Hunter, E., & Spearman, P. W. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1504174112 · Cited by 49 · see citing works

Effects of HIV Type 1 Envelope Glycoprotein Proteolytic Processing on Antigenicity

Si, Z., Phan, N. M. H., Kiprilov, E., & Sodroski, J. (2003) · AIDS Research and Human Retroviruses · doi:10.1089/088922203763315722 · Cited by 47 · see citing works

Only Five of 10 Strictly Conserved Disulfide Bonds Are Essential for Folding and Eight for Function of the HIV-1 Envelope Glycoprotein

van Anken, E., Sanders, R. W., Liscaljet, I. M., Land, A., Bontjer, I., Tillemans, S., Nabatov, A. A., Paxton, W. A., Berkhout, B., & Braakman, I. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-12-1282 · Cited by 45 · see citing works

Topology of the C-Terminal Tail of HIV-1 gp41: Differential Exposure of the Kennedy Epitope on Cell and Viral Membranes

Steckbeck, J. D., Sun, C., Sturgeon, T. J., & Montelaro, R. C. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015261 · Cited by 40 · see citing works

Highly Conserved Structural Properties of the C-terminal Tail of HIV-1 gp41 Protein Despite Substantial Sequence Variation among Diverse Clades

Steckbeck, J. D., Craigo, J. K., Barnes, C. O., & Montelaro, R. C. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.258855 · Cited by 39 · see citing works

Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity

Rawson, J. M. O., Nikolaitchik, O. A., Keele, B. F., Pathak, V. K., & Hu, W.-S. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky910 · Cited by 39 · see citing works

Signal peptide of HIV-1 envelope modulates glycosylation impacting exposure of V1V2 and other epitopes

Upadhyay, C., Feyznezhad, R., Cao, L., Chan, K.-W., Liu, K., Yang, W., Zhang, H., Yolitz, J., Arthos, J. A., Nadas, A. J., et al. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1009185 · Cited by 37 · see citing works

Analysis of HIV-1 Matrix-Envelope Cytoplasmic Tail Interactions

Alfadhli, A., Staubus, A. O., Tedbury, P. R., Novikova, M., Freed, E. O., & Barklis, E. (2019) · Journal of Virology · doi:10.1128/jvi.01079-19 · Cited by 36 · see citing works

NMR Model of the Entire Membrane-Interacting Region of the HIV-1 Fusion Protein and Its Perturbation of Membrane Morphology

Piai, A., Fu, Q., Sharp, A. K., Bighi, B., Brown, A. M., & Chou, J. J. (2021) · Journal of the American Chemical Society · doi:10.1021/jacs.1c01762 · Cited by 36 · see citing works

Reevaluation of the Requirement for TIP47 in Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Incorporation

Checkley, M., Luttge, B., Mercredi, P. Y., Kyere, S., Donlan, J., Murakami, T., Summers, M., Cocklin, S., & Freed, E. (2013) · Journal of Virology · doi:10.1128/jvi.03299-12 · Cited by 35 · see citing works

Dual Pathways of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Trafficking Modulate the Selective Exclusion of Uncleaved Oligomers from Virions

Zhang, S., Nguyen, H., Ding, H., Wang, J., Zou, S.-T., Liu, L.-H., Guha, D., Gabuzda, D., Ho, D., Kappes, J., et al. (2020) · Journal of Virology · doi:10.1128/jvi.01369-20 · Cited by 35 · see citing works

Impact of Natural Polymorphism within the gp41 Cytoplasmic Tail of Human Immunodeficiency Virus Type 1 on the Intracellular Distribution of Envelope Glycoproteins and Viral Assembly

Lambelé, M., Labrosse, B., Roch, E., Moreau, A., Verrier, B., Barin, F., Roingeard, P., Mammano, F., & Brand, D. (2006) · Journal of Virology · doi:10.1128/jvi.01659-06 · Cited by 35 · see citing works

Budding of a Retrovirus: Some Assemblies Required

Rose, K. M., Hirsch, V. M., & Bouamr, F. (2020) · Viruses · doi:10.3390/v12101188 · Cited by 32 · cited 1× · see citing works

Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity

Rathore, U., Saha, P., Kesavardhana, S., Kumar, A. A., Datta, R., Sankar, D. S., Das, R., Mascola, J. R., & Varadarajan, R. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.788919 · Cited by 31 · see citing works

HIV-1 Matrix Trimerization-Impaired Mutants Are Rescued by Matrix Substitutions That Enhance Envelope Glycoprotein Incorporation

Tedbury, P. R., Novikova, M., Alfadhli, A., Hikichi, Y., Kagiampakis, I., KewalRamani, V. N., Barklis, E., & Freed, E. O. (2019) · Journal of Virology · doi:10.1128/jvi.01526-19 · Cited by 28 · see citing works

Effect of Promoters and Signal Sequences on the Production of Secreted HIV-1 gp120 Protein in the Baculovirus System

Golden, A., Austen, D. A., van Schravendijk, M. R., Sullivan, B. J., Kawasaki, E. S., & Osburne, M. S. (1998) · Protein Expression and Purification · doi:10.1006/prep.1998.0926 · Cited by 28 · see citing works

Diacylglycerol Kinase α Regulates Tubular Recycling Endosome Biogenesis and Major Histocompatibility Complex Class I Recycling

Xie, S., Naslavsky, N., & Caplan, S. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.594291 · Cited by 27 · see citing works

HIV-1 Cell-Free and Cell-to-Cell Infections Are Differentially Regulated by Distinct Determinants in the Env gp41 Cytoplasmic Tail

Durham, N. D., & Chen, B. K. (2015) · Journal of Virology · doi:10.1128/jvi.00655-15 · Cited by 24 · see citing works

Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations

Upadhyay, C., Feyznezhad, R., Yang, W., Zhang, H., Zolla‐Pazner, S., & Hioe, C. E. (2018) · PLoS Pathogens · doi:10.1371/journal.ppat.1006812 · Cited by 24 · see citing works

Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif

Breed, M. W., Elser, S. E., Torben, W., Jordan, A. P. O., Aye, P. P., Midkiff, C. C., Schiro, F. R., Sugimoto, C., Alvarez-Hernandez, X., Blair, R. V., et al. (2015) · Journal of Virology · doi:10.1128/jvi.01134-15 · Cited by 23 · see citing works

SnapShot: Influenza by the Numbers

Einav, T., Gentles, L. E., & Bloom, J. D. (2020) · Cell · doi:10.1016/j.cell.2020.05.004 · Cited by 22 · see citing works

Effects of signal peptide exchange on HIV‐1 glycoprotein expression and viral infectivity in mammalian cells

Pfeiffer, T., Pisch, T., Devitt, G., Holtkotte, D., & Bosch, V. (2006) · FEBS Letters · doi:10.1016/j.febslet.2006.05.070 · Cited by 21 · see citing works

Mapping of Domains on HIV Envelope Protein Mediating Association with Calnexin and Protein-disulfide Isomerase

Papandréou, M., Barbouche, R., Guieu, R., Rivera, S., Fantini, J., Khrestchatisky, M., Jones, I. M., & Fenouillet, E. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.066670 · Cited by 14 · see citing works

REPLICATION OF HIV-1 ENVELOPE PROTEIN CYTOPLASMIC DOMAIN VARIANTS IN PERMISSIVE AND RESTRICTIVE CELLS

Staubus, A., Alfadhli, A., Barklis, R. L., & Barklis, E. (2019) · Virology · doi:10.1016/j.virol.2019.09.008 · Cited by 10 · see citing works

Unique Functional Properties of Conserved Arginine Residues in the Lentivirus Lytic Peptide Domains of the C-terminal Tail of HIV-1 gp41

Kuhlmann, A.-S., Steckbeck, J. D., Sturgeon, T. J., Craigo, J. K., & Montelaro, R. C. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.529339 · Cited by 10 · see citing works

Efficiency of Erythropoietin's Signal Peptide for HIVMN-1 gp 120 Expression

Herrera, A. M., Musacchio, A., Fernández, J. R., & Duarte, C. A. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.2974 · Cited by 10 · see citing works

A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection

Lawrence, S. P., Elser, S. E., Torben, W., Blair, R. V., Pahar, B., Aye, P. P., Schiro, F. R., Szeltner, D. M., Doyle‐Meyers, L. A., Haggarty, B., et al. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010507 · Cited by 8 · see citing works

A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread

Snetkov, X., Haider, T., Mesner, D., Groves, N. S., van Engelenburg, S. B., & Jolly, C. L. (2022) · Viruses · doi:10.3390/v14010129 · Cited by 6 · see citing works

The HIV-1 envelope glycoprotein: structure, function and interactions with neutralizing antibodies

Klasse, P. J., Sanders, R. W., Ward, A. B., Wilson, I. A., & Moore, J. P. (2025) · Nature Reviews Microbiology · doi:10.1038/s41579-025-01206-6 · Cited by 36 · see citing works

Get in and get out: Remodeling of the cellular actin cytoskeleton upon HIV‐1 infection

Serrano, T., Frémont, S., & Échard, A. (2023) · Biology of the Cell · doi:10.1111/boc.202200085 · Cited by 17 · see citing works

The Dual Function of RhoGDI2 in Immunity and Cancer

Tripathi, M., Colige, A., & Deroanne, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24044015 · Cited by 12 · see citing works

Analysis of HIV-1 envelope cytoplasmic tail effects on viral replication

Alfadhli, A., Romanaggi, C., Barklis, R. L., & Barklis, E. (2023) · Virology · doi:10.1016/j.virol.2022.12.017 · Cited by 9 · see citing works

MicroRNAs in HIV infection: dual regulators of viral replication and host immunity

Mansour, R. M., El-Sayyad, G. S., Rizk, N. I., Mageed, S. S. A., Basiouny, M. S., Elsayed, S. S. M., Fayez, S. Z., Abdelaziz, M. M., Abuelhaded, K., Fahmy, H. A., et al. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-03893-7 · Cited by 8 · see citing works

Adaptor Protein Complexes in HIV-1 Pathogenesis: Mechanisms and Therapeutic Potential

Barone, M. E., Lim, A., Woody, M., Taklifi, P., Yeasmin, F., Wang, K., Lewinski, M. K., Singh, R., Stoneham, C. A., Jia, X., et al. (2025) · Viruses · doi:10.3390/v17050715 · Cited by 7 · see citing works

KIF16B Mediates Anterograde Transport and Modulates Lysosomal Degradation of the HIV-1 Envelope Glycoprotein

Weaver, N. C., Hammonds, J. E., Ding, L., Lerner, G., Dienger-Stambaugh, K., & Spearman, P. W. (2023) · Journal of Virology · doi:10.1128/jvi.00255-23 · Cited by 6 · see citing works

Probing Gag-Env dynamics at HIV-1 assembly sites using live-cell microscopy

Muecksch, F., Klaus, S., Laketa, V., Müller, B., & Kräusslich, H. (2024) · Journal of Virology · doi:10.1128/jvi.00649-24 · Cited by 6 · see citing works

Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication

Jehad, M. A., Ali, L. M., Pillai, V. N., Prabhu, S. G., Mustafa, F., & Rizvi, T. A. (2026) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuaf066 · Cited by 5 · see citing works

Characterization of full-length and cytoplasmic tail-truncated envelope glycoproteins incorporated into human immunodeficiency virus (HIV-1) virions and virus-like particles

Anang, S., Zhang, S., Ennis, A., Ding, H., Deshpande, A. A., Nguyen, H. T., Kappes, J. C., & Sodroski, J. (2025) · Journal of Virology · doi:10.1128/jvi.01585-25 · Cited by 5 · see citing works

Second site reversion of HIV-1 envelope protein baseplate mutations maps to the matrix protein

Alfadhli, A., Romanaggi, C., Barklis, R. L., & Barklis, E. (2024) · Journal of Virology · doi:10.1128/jvi.01742-23 · Cited by 5 · see citing works

Tryptophan-based motifs in the LLP3 region of the HIV-1 envelope glycoprotein cytoplasmic tail direct trafficking to the endosomal recycling compartment and mediate particle incorporation

Lerner, G., Ding, L., & Spearman, P. W. (2023) · Journal of Virology · doi:10.1128/jvi.00631-23 · Cited by 4 · see citing works

Molecular Genetics of Retrovirus Replication

Levin, J. G., Musier‐Forsyth, K., & Rein, A. R. (2023) · Viruses · doi:10.3390/v15071549 · Cited by 4 · see citing works

The Assembly of HTLV-1—How Does It Differ from HIV-1?

Herrmann, D., Meng, S., Yang, H., Mansky, L. M., & Saad, J. S. (2024) · Viruses · doi:10.3390/v16101528 · Cited by 3 · see citing works

Type I interferons sensitise HIV-1-reactivating T-cells for NK cell-mediated elimination despite HDACi-imposed dysregulation of innate immunityPreprint

Kazmierski, J., Postmus, D., Pietrobon, A. J., Wyler, E., Jansen, J., Møller, L. F., Fadejeva, J., Steijaert, T. H., Fischer, C., Koppe, U., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.04.075119 · Cited by 3 · see citing works

Poly (ADP-ribose) polymerase-1 regulates HIV-1 replication in human CD4+ T cellsPreprint

Martinez, Z. S., Gutiérrez, D. A., Valenzuela, C. A., Seong, C.-S., & Llano, M. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.11.598467 · Cited by 3 · see citing works

Incorporation of the HIV-1 envelope glycoprotein into viral particles is regulated by the tubular recycling endosome in a cell type-specific mannerPreprint

Lerner, G., Ding, L., Candor, K., & Spearman, P. W. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.17.572063 · Cited by 2 · see citing works

Endocytic motif on HIV-1 Env regulates cleavage status and antibody neutralization of cell-free and cell-to-cell infection

Figueroa, D. M., Valencia, T. R., Li, H., & Chen, B. K. (2026) · Journal of Virology · doi:10.1128/jvi.01542-25 · Cited by 1 · see citing works

Mechanisms of HIV-1 assembly, release and maturation

Kleinpeter, A. B., & Freed, E. O. (2026) · Nature Reviews Microbiology · doi:10.1038/s41579-026-01327-6 · Cited by 1 · see citing works

Contribution of endosomal proteins EHD1 and EHD4 to the HIV ‐1 replication cycle

Pacini, G., Poalas, K., Versapuech, M., Berlioz‐Torrent, C., & Janvier, K. (2026) · FEBS Journal · doi:10.1111/febs.70639

HIV-1 Env Heterogeneity: Cleavage, Trafficking, and Antigenic Consequences for Virions and Infected Cells

Figueroa, D. M., Khaleeq, S., Weiß, S., Valencia, T., Mason, G., & Chen, B. K. (2026) · Viruses · doi:10.3390/v18080811

HIV-1 Envelope Glycoprotein Trafficking through the Endosomal Recycling Compartment Is Required for Particle Incorporation

Kirschman, J., Qi, M., Ding, L., Hammonds, J. E., Dienger-Stambaugh, K., Wang, J.-J., Lapierre, L. A., Goldenring, J. R., & Spearman, P. W. (2017) · Journal of Virology · doi:10.1128/jvi.01893-17 · Cited by 51 · see citing works

Incorporation of the HIV-1 envelope glycoprotein into viral particles is regulated by the tubular recycling endosome in a cell type-specific mannerPreprint

Lerner, G., Ding, L., Candor, K., & Spearman, P. W. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.17.572063 · Cited by 2 · see citing works

Tryptophan-based motifs in the LLP3 region of the HIV-1 envelope glycoprotein cytoplasmic tail direct trafficking to the endosomal recycling compartment and mediate particle incorporation

Lerner, G., Ding, L., & Spearman, P. W. (2023) · Journal of Virology · doi:10.1128/jvi.00631-23 · Cited by 4 · see citing works

HIV-1 Envelope Glycoprotein Biosynthesis, Trafficking, and Incorporation

Checkley, M. A., Luttge, B. G., & Freed, E. O. (2011) · Journal of Molecular Biology · doi:10.1016/j.jmb.2011.04.042 · Cited by 477 · see citing works

Rab11-FIP1C and Rab14 Direct Plasma Membrane Sorting and Particle Incorporation of the HIV-1 Envelope Glycoprotein Complex

Qi, M., Williams, J. A., Chu, H., Chen, X., Wang, J.-J., Ding, L., Akhirome, E., Wen, X., Lapierre, L. A., Goldenring, J. R., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003278 · Cited by 106 · see citing works