The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
Herpesviruses: latency and reactivation – viral strategies and host response
Open accessAbstract
Eight members of the Herpesviridae family commonly infect humans, and close to 100% of the adult population is infected with at least one of these. The five that cause the most health concerns are: herpes simplex virus (HSV) type 1 and 2, Epstein-Barr virus (EBV), cytomegalovirus (CMV), and varicella zoster virus (VZV). In addition, there are human herpes virus (HHV) types 6-8. The review starts by introducing possible viral strategies in general. The particular biology and host relationship of the various human herpesviruses, including their pathology, are examined subsequently. Factors that contribute to the maintenance of latency and reactivation of viral replication are discussed. There will be special reference to how these viruses exploit and contribute to pathology in the oral cavity. Reactivation does not necessarily imply clinical symptoms, as reflected in the asymptomatic shedding of EBV and CMV from oral mucosa. The immune response and the level of viral output are both important to the consequences experienced.
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Cites
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Herpesvirus latency confers symbiotic protection from bacterial infection
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Viruses, microRNAs, and Host Interactions
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Decoding Human Cytomegalovirus
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Herpes Simplex Epithelial and Stromal Keratitis: An Epidemiologic Update
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A population-based study of primary human herpesvirus 6 infection
Zerr, D. M., Meier, A. S., Selke, S. S., Frenkel, L. M., Huang, M.-L., Wald, A., Rhoads, M. P., Nguy, L., Bornemann, R., Morrow, R. A., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa042207 · Cited by 462
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Cited by
Epidemiology and Immune Pathogenesis of Viral Sepsis
Lin, G.-L., McGinley, J. P., Drysdale, S. B., & Pollard, A. J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02147 · Cited by 351
Herpes Virus Reactivation in Astronauts During Spaceflight and Its Application on Earth
Rooney, B. V., Crucian, B. E., Pierson, D. L., Laudenslager, M. L., & Mehta, S. K. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00016 · Cited by 174
The Pathogenesis and Immune Evasive Mechanisms of Equine Herpesvirus Type 1
Laval, K., Poelaert, K. C. K., Van Cleemput, J., Zhao, J., Vandekerckhove, A. P., Gryspeerdt, A. C., Garré, B., van der Meulen, K., Baghi, H. B., Dubale, H. N., et al. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.662686 · Cited by 54
“A hallmark of herpesviruses is the establishment of a reactivable, latent infection in its host (Grinde, 2013).”
BackgroundMechanistic insights into the role of herpes simplex virus 1 in Alzheimer’s disease
Feng, S., Liu, Y., Zhou, Y., Shu, Z., Cheng, Z., Brenner, C., & Feng, P. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1245904 · Cited by 36
Spaceflight virology: what do we know about viral threats in the spaceflight environment?
Pavletić, B., Runzheimer, K., Siems, K., Koch, S., Cortesão, M., Ramos-Nascimento, A., & Moeller, R. (2022) · Astrobiology · doi:10.1089/ast.2021.0009 · Cited by 30
Metadata
- Authors
- Grinde, B.
- Venue
- Journal of Oral Microbiology
- Publisher
- Informa UK Limited
- Published
- 2013-01-01
- Volume
- 5
- Issue
- 1
- Pages
- 22766
- ISSN
- 2000-2297 (ISSN-L)
- OpenAlex
- W2034892842
- Cited by
- 489
- References
- 44
- FWCI
- 13.40
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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