Cited by 47Gastrointestinal motility and disordersGut microbiota and healthPsychosomatic Disorders and Their Treatments

Functional dyspepsia and irritable bowel syndrome, are they different entities and does it matter

Open access
Gwee, Kok-Ann·2006·World Journal of Gastroenterology

Abstract

A high prevalence of overlap between functional dyspepsia and irritable bowel syndrome has been consistently and universally reported. Recent studies demonstrating shared common pathophysiological disturbances including delayed gastric emptying and visceral hypersensitivity involving more than one region, suggest that these patients have a generalised rather than regional, disorder of the gut. Furthermore, a study of the natural history of dyspepsia suggests that with time, a substantial proportion will evolve into IBS. The recognition of IBS in dyspeptic patients has potentially profound therapeutic importance. It could help to reduce the risk of unnecessary cholecystectomy in IBS patients. The ability to appreciate the extent of involvement could allow us to address the disturbances more comprehensively, and thereby achieve greater patient satisfaction with their treatment.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.3748/wjg.v12.i17.2708

Cites

43 of 43 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • IBS and FD share a similar profile of patients (female predominance, high levels of psychological co-morbidities) and pathophysiologic mechanisms, mainly visceral hypersensitivity.

    “These 2 entities also share a similar profile of patients (female predominance, high levels of psychological co-morbidities) and pathophysiologic mechanisms, mainly visceral hypersensitivity.”

    From Irritable Bowel Syndrome and Co-morbid Gastrointestinal and Extra-gastrointestinal Functional Syndromes (2010) · cites this paper as [15]

    The “Shared Common Pathophysiological Disturbances” and “Visceral hypersensitivity” sections support visceral hypersensitivity as a mechanism found in both FD and IBS. Our copy does not establish the claimed female predominance or high levels of psychological comorbidity in both patient groups (searched: female, psychological, and related terms). (LLM, conf=0.88)

    Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 2

  1. Chen MH, Zhong BB, Li CJ. A epidemiological study of dys- pepsia in Guangdong area. J Gastroenterol Hepatol 1997; 12 : A199
  2. Gwee KA, Teng L, Yeoh KG, Ho KY. Patients with functional dyspepsia who have symptoms of irritable bowel syndrome are more likely to have dysmotility-like than ulcer-like dys- pepsia. Neurogastroenterol Motil 2000; 12: 387

Cited by

Sorted by citations

Authors
Gwee, K.-A.
Affiliations
Gleneagles Hospital (SG)
Corresponding author
Gwee, Kok-Ann
Venue
World Journal of Gastroenterology
Published
2006
Volume
12
Issue
17
Pages
2708
ISSN
1007-9327 (ISSN-L)
OpenAlex
W7947047
Cited by
47
References
43
Citations by year
2026: 3 · 2025: 1 · 2024: 2 · 2023: 4 · 2022: 1 · 2021: 1 · 2020: 3 · 2018: 5 · 2016: 4 · 2015: 3 · 2014: 1 · 2013: 1 · 2012: 2
FWCI
0.50
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • World Journal of Gastroenterology (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • National University of Singapore (submittedVersion)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Keywords
functional dyspepsia, irritable bowel syndrome, delayed gastric emptying, visceral hypersensitivity, cholecystectomy, gastrointestinal motility disorders, dyspepsia treatment
MeSH terms
Diagnosis, Differential, Dyspepsia, Gastric Emptying, Gastrointestinal Diseases, Humans, Prevalence, Gastrointestinal Tract, Irritable Bowel Syndrome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review