The DOI matches its Crossref record; 112 of the 112 references it cites were found in a registry or an index.
Mediterranean diet and nonalcoholic fatty liver disease
Open accessAbstract
Nonalcoholic fatty liver disease (NAFLD) is emerging as the most common chronic liver disease, and is characterized by a wide spectrum of fat-liver disorders that can result in severe liver disease and cirrhosis. Inflammation and oxidative stress are the major risk factors involved in the pathogenesis of NAFLD. Currently, there is no consensus concerning the pharmacological treatment of NAFLD. However, lifestyle interventions based on exercise and a balanced diet for quality and quantity, are considered the cornerstone of NAFLD management. Mediterranean diet (MD), rich in polyunsaturated fats, polyphenols, vitamins and carotenoids, with their anti-inflammatory and anti-oxidant effects, has been suggested to be effective in preventing cardiovascular risk factors. In adults, MD has also been demonstrated to be efficacious in reducing the risk of metabolic syndrome. However, few studies are available on the effects of the MD in both adult and pediatric subjects with NAFLD. Thus, the aims of the present narrative review are to analyze the current clinical evidence on the impact of MD in patients with NAFLD, and to summarize the main mechanisms of action of MD components on this condition.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“omega-3 PUFAs, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are renowned for their antioxidant and anti-inflammatory properties (95–97).”
From Diet and physical exercise as key players to tackle MASLD through improvement of insulin resistance and metabolic flexibility (2024) · cites this paper as [96]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2 retracted
RETRACTED: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet
Estruch, R., Ros, E., Salas-Salvadó, J., Covas, M.-I., Corella, D., Arós, F., Gómez-Gracia, E., Ruiz-Gutiérrez, V., Fiol, M., Lapetra, J., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1200303 · Cited by 4,257
RetractedEstruch, R., Ros, E., Salas-Salvadó, J., Covas, M.-I., Corella, D., Arós, F., Gómez-Gracia, E., Ruiz-Gutiérrez, V., Fiol, M., Lapetra, J., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmc1806491 · Cited by 1,008
RetractedYaşlı Kadınlarda Üreme Sağlığı
Kokanalı, D., & Engin Üstün, Y. (n.d.) · DergiPark (Istanbul University) · Cited by 170,090
Diet rapidly and reproducibly alters the human gut microbiome
David, L. A., Maurice, C. F., Carmody, R. N., Gootenberg, D. B., Button, J. E., Wolfe, B. E., Ling, A. V., Devlin, A. S., Varma, Y., Fischbach, M. A., et al. (2014) · Nature · doi:10.1038/nature12820 · Cited by 10,100
Mechanisms linking obesity to insulin resistance and type 2 diabetes
Kahn, S. E., Hull, R. L., & Utzschneider, K. M. (2006) · Nature · doi:10.1038/nature05482 · Cited by 5,448
Nonalcoholic Fatty Liver Disease
Angulo, P. (2002) · New England Journal of Medicine · doi:10.1056/nejmra011775 · Cited by 5,228
EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease
(2016) · Journal of Hepatology · doi:10.1016/j.jhep.2015.11.004 · Cited by 4,836
Adherence to a Mediterranean diet and survival in a Greek population
Trichopoulou, A., Costacou, T., Bamia, C., & Trichopoulos, D. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa025039 · Cited by 4,397
A short questionnaire for the measurement of habitual physical activity in epidemiological studies
Baecke, J. A. H., BUREMA, J., & Frijters, J. E. R. (1982) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/36.5.936 · Cited by 3,950
The impact of the gut microbiota on human health: an integrative view
Clemente, J. C., Ursell, L. K., Parfrey, L. W., & Knight, R. (2012) · Cell · doi:10.1016/j.cell.2012.01.035 · Cited by 3,710
Cited by
Sorted by citations
Items 301–352 of 352
Simeoni, S., & Catalano, D. (2016) · Journal of Functional Morphology and Kinesiology · doi:10.3390/jfmk1030303
Nutrition in Inflammatory Lung Diseases
Aguilar-López, D. K., Sandoval, C. O., Estrada-Luna, D., Vega, J. A. I., Sharma, A. K., & Cabrera, G. B. (2019) · Springer eBooks · doi:10.1007/978-981-13-8413-4_1
Das Leben und das Essen trotz nichtalkoholischer Fettleber genießen
Bojunga, J., Meyer, G., & Mondorf, A. W. (2019) · Info Diabetologie · doi:10.1007/s15034-019-1527-1
Nonalcoholic Fatty Liver Disease in Children: Spectrum and Consequences
Aneja, A., & Lal, S. B. (2021) · Journal of Postgraduate Medicine Education and Research · doi:10.5005/jp-journals-10028-1429
Bischoff, S. C., Bernal, W. E., Dasarathy, S., Merli, M., Plank, L. D., Schütz, T., Plauth, M., Скрипник, І. М., & Shvets, O. (2021) · Modern Gastroenterology · doi:10.30978/mg-2021-1-59
Grün, sauer, bitter: Ernährungstherapie für die Leber
März, H. (2020) · Deutsche Heilpraktiker-Zeitschrift · doi:10.1055/a-1221-6911
Kırık, A., Gürel, H., TÜREL, S., & Şen, H. (2021) · Ahi Evran Medical Journal · doi:10.46332/aemj.961389
Oliveira, M. R., Ferreira, M. S., Delgado, L. F., Dazini, P. O., Ronzani, F. A. T., Lanna, C. M. M., & Luquetti, S. C. P. D. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/211205111
O desenho-história em Arteterapia no processo de reabilitação de dependentes de drogas psicoativas
Torres, A., & da Câmara, M. V. S. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/211205082
REDES DE ATENÇÃO À SAÚDE, PANORAMA E DESAFIOS NA PERSPECTIVA DE GESTORES, PROFISSIONAIS E USUÁRIOS
Campos, A. A. R., de Oliveira, M. C., & Kanan, L. A. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/211205121
O VISAGISMO E A SUA APLICABILIDADE NA ODONTOLOGIA
de Souza, C. F. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/211205133
O TRANSTORNO DE PERSONALIDADE NARCISISTA E AS RELAÇÕES AFETIVAS: UMA CONTRIBUIÇÃO DA PSICANÁLISE
da Fonseca, A. A., Leôncio, E. É., & Lins, T. K. D. B. P. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/211205176
Avaliação computacional de parâmetros radiobiológicos para um caso de glioblastoma multiforme
Fröhlich, L., do Santos, M. M., Sánchez, M. S. A., Botelho, V. R., & Pianoschi, T. A. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/211205085
Atividade antioxidante, composição centesimal e mineral de cogumelos Pleurotus ostreatus
Junior, N., & Oliveira, M. G. D. A. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/211205125
Cunha, F. M. A. M. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/211205144
Atendimento fisioterapêutico em paciente lesado medular: Relato de Experiência
Andrade, T. H., Oliveira, M. S., & Franco, F. S. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/211205120
Tavares, W. A., Souza, G. D. A., Filho, H. M. G. G., & Alexandre, S. F. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/211205137
Antibiofilm activity of glycolic plant extracts on Klebsiella pneumoniaeclinical isolates
de Lima, P. M. N., Ramos, L. D. P., Pereira, T. C., Oliveira, M. D. S., Assis, M. A. D. S., Amaral, S. S., Figueira, L. W., Santos, C. E. R., dos Santos, J. M. T., & de Oliveira, L. D. (2021) · Editora Conhecimento Livre eBooks · doi:10.37423/211205139
Porras, D. (2021) · Buleria (Universidad de León) · doi:10.18002/10612/13641
Livzan, M. A., Gaus, O. V., & Fedorin, M. M. (2023) · Russian Medical Inquiry · doi:10.32364/2587-6821-2023-7-5-11
Козак, О. А., & Господарський, І. Я. (2023) · Здобутки клінічної і експериментальної медицини · doi:10.11603/1811-2471.2023.v.i3.14003
Covid-19 Döneminde Kentsel Ve Kırsal Alanlarda Yaşayan Bireylerin Beslenme Alışkanlıkları
ÖNAL, H. Y., ÖZGENÇ, B., PULAT, B., ZORTUK, Y., ÇOKOKUR, S. A., Yoldaş, K., Koçak, B., & Alphan, M. E. (2023) · Türkiye Sağlık Bilimleri ve Araştırmaları Dergisi · doi:10.51536/tusbad.1381385
Akdeniz diyeti ve Non alkolik yağlı karaciğer hastalığı
Bektaş, A., & Ulusoy, M. (2023) · Troia Medical Journal · doi:10.55665/troiamedj.1363991
Twenty four food intakes and nonalcoholic fatty liver disease: A Mendelian randomization studyPreprint
Chen, Z., Li, C., Gao, T., & Ke, D. (2024) · Research Square · doi:10.21203/rs.3.rs-4066050/v1
Nonpharmacologic and nonsurgical treatment of NAFLD/NASH, obesity, and metabolic disease
Balogun, O. O., Shaikh, E. S., & Corey, K. E. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99649-5.00018-2
Principles of Nutrition in Patients with Non-alcoholic Fatty Liver Disease
Mobasheri, N., Ghahremani, L., & Nazari, M. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.1008363
The Role of Gut Microbiota in Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD)
Bucurica, S. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.1008148
Non alkolik yağlı karaciğer hastalığı ile kafein alımı arasındaki ilişki
Akkaya, İ., & Yıldırım, İ. G. (2025) · Sağlık Profesyonelleri Araştırma Dergisi · doi:10.57224/jhpr.1555046
Alhouei, B., & Doaei, S. (2025) · Food Science and Nutrition Cases · doi:10.1079/fsncases.2025.0014
Bioactive Phytochemical–Based Nanocarriers for Targeting Non‐Alcoholic Fatty Liver Disease (NAFLD)
Kumar, G., Fathima, S., Gurram, P. C., Bala, C., Sindhu, R. K., & Begum, F. (2025) · Wiley eBooks · doi:10.1002/9781394287345.ch16
Cernea, S., Onișor, D. M., & Roiban, A. L. (2025) · Acta Marisiensis. Seria Medica · doi:10.2478/amma-2025-0030
hasannia, F., Keshavarz, S. A., & Shadnoush, M. (2025) · Journal of Nutrition Sciences and Food Technology · doi:10.61882/nsft.20.3.21
Fatigue in Cholestatic Liver Disease: A Review of Mechanisms and Non-Pharmacological Management
Isley, S., Johnson, E., Swain, M. G., & Tandon, P. (2025) · Current Hepatology Reports · doi:10.1007/s11901-025-00706-6
“Evidence from other chronic disease populations sug - gests that a Mediterranean-style diet may be effective for fatigue management, likely through its anti-inflammatory and metabolic benefits [ 86–88 ].”
Godria, P., Patel, C., Patel, H., Thaker, P., Bhuva, R., Patel, D. M., & Bhudhrani, D. S. (2025) · International Journal of Research in Medical Sciences · doi:10.18203/2320-6012.ijrms20253602
Alarming Global Rise in Adolescent Metabolic Dysfunction‐Associated Steatotic Liver Disease by 2030
Li, X., & Hua, Y. (2025) · Acta Paediatrica · doi:10.1111/apa.70373 · Cited by 1
Azevedo, S. A. D., Costa, A. C. X., Rego, K. A. D. S., Oliveira, F. D. S., Mantesso, J. B. D. O., Paiva, G. S. C., Falcão, A. D. S., & Mignoni, M. S. P. M. (2025) · Aracê. · doi:10.56238/arev7n11-266
Petermann-Rocha, F., Wirth, M. D., Boonpor, J., Parra-Soto, S. L., Zhou, Z., Mathers, J. C., Livingstone, K., Forrest, E., Pell, J. P., Ho, F. K., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22622068
Wang, H., Li, H., Liu, Y., Wang, X., He, C., Huang, J., Zhang, Y., Yang, Y., & Ge, N. N. (2026) · Hepatology Communications · doi:10.1097/hc9.0000000000000866
Zheng, H., Yao, Y.-H., Li, S., & Liu, L. (2026) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.70349
Kou, Y., Yang, J., Yuan, G., Zhong, G., Chen, F., Liang, M., Huang, Y., He, K., Lin, Y., Huang, Z., et al. (2026) · Comprehensive physiology · doi:10.1002/cph4.70135
Zraiby, M. R.-E. (2019) · doi:10.70675/91fc6a76z3cf2z4911za47bz997596a26dd8
“n (%) n (%) n (%) Age, années 59,9 [52,1-65,5] 59,8 [53,5-66,4] 61,7 [55,9-68,3] 0,027 Sexe 0,119 Homme 134 (68,7) 141 (71,6) 148 (77,9) Niveau d’éducation 0,702 ≤12 ans d’études 169 (87,1) 170 (86,3) 160 (84,2) Plus de 12 ans d’études ou diplôme des grandes écoles/universitaire 25 (12,9) 27 (13,7) 30 (15,8) Activité…”
BackgroundLiu, J.-R., Zhao, L., Niu, Q., Cai, J.-Z., & Liu, H.-Y. (2026) · World Journal of Gastrointestinal Surgery · doi:10.4240/wjgs.121285
Dietary polyphenols in pediatric obesity and cardiometabolic risk: mechanisms and clinical evidence
Calcaterra, V., Cena, H., Conti, M. V., Scavone, I. A. M., Basilico, S., Quatrale, A. E., & Zuccotti, G. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1849842 · Cited by 1
“Dietary patterns rich in plant-derived bioactive compounds have been associated with improved lipid profiles and reduced hepatic fat accumulation (60), partly attributable to the anti-inflammatory and antioxidant properties of polyphenols (109).”
Ahmad, T., Samee-Ullah, Saeed, M., Shaukat, F., Huang, J., Khalid, S., Sun, J., Sun, X., Guo, Y., Du, F., et al. (2026) · Food Reviews International · doi:10.1080/87559129.2026.2699348
Javaheri‐Tafti, F., Ghaeminejad, Z., Boroujeni, L. Z. B., Naghshi, N., Hekmatdoost, A., Pashayee-Khamene, F., Karimi, S., Ahmadzadeh, S., Saberifiroozi, M., Hatami, B., et al. (2026) · Health Science Reports · doi:10.1002/hsr2.72936
Silva, R. R., Lima, J. A., Cantador, V. H. C., Teixeira, M. C. C., Santos, D. R., Durante, L. H. C., Paludetto, L. S., Mata, A. C. C., & Moraes, K. C. M. (2026) · Brazilian Journal of Biology · doi:10.1590/1519-6984.304026
Han, Z., Song, H., Wang, C., Li, Q., Ye, Y., Liu, W., Pang, G., Sun, W., Zhu, X., Wang, S., et al. (2026) · Annals of Surgical Oncology · doi:10.1245/s10434-026-20370-4
“23 –26 Indeed, a case-control study of 518 cases of HCC and 772 controls has reported that the level of adherence to the MD is significantly and inversely correlated with the risk of HCC in a nearly mono-tonic manner.”
The global cardiovascular-kidney-liver-metabolic burden from 1990 to 2023
Jayabaskaran, J., Himan, H. R., Nagarajan, S., Chong, B., Chen, Y., Tan, E. E.-R., le Roux, C. W., Khan, M. S., Mehta, A., Muthiah, M. D., et al. (2026) · EClinicalMedicine · doi:10.1016/j.eclinm.2026.104155
“77,78 83 While policy-driven strategies, that include sugar taxation, front-of-pack food labeling, and nationwide physical activity promotion 79 have tried to tackle upstream determinants of the CKLM burden, the sustainability of such public health strategies are often complex, less effective than…”
Aljarallah, B. M. (2026) · Advances in Human Biology · doi:10.4103/aihb.aihb_31_26
Wang, W., Tang, Y., Wan, Z., Zhang, Z., Zheng, Z., Liu, H., Shu, Q., & Li, S. (2026) · Pharmacological Research · doi:10.1016/j.phrs.2026.108444
Eighty Years After Vague: Advances in Understanding Ectopic Fat and Metabolic Dysfunction
Conte, C., Sumithran, P., le Roux, C. W., Miras, A. D., & Gaal, L. V. (2026) · Obesity Reviews · doi:10.1111/obr.70229
Endocrine determinants of MASLD: mechanisms and therapeutic targets
Chaturvedi, R., Mathew, A., Pradhan, A., Goyal, M., Sharma, M., Kachroo, V., Agrawal, C., Krishnamurthy, A., Atreja, S. M., & Atreja, A. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1967494
Metadata
- Authors
- Anania, C., Perla, F. M., Olivero, F., Pacifico, L., & Chiesa, C.
- Affiliations
- Policlinico Umberto I (IT)
- Corresponding author
- Chiesa, Claudio
- Venue
- World Journal of Gastroenterology
- Publisher
- Baishideng Publishing Group Inc.
- Published
- 2018-05-21
- Volume
- 24
- Issue
- 19
- Pages
- 2083-2094
- ISSN
- 1007-9327 (ISSN-L)
- PMC
- PMC5960814
- OpenAlex
- W2803151742
- Cited by
- 353
- References
- 112
- Citations by year
- 2026: 23 · 2025: 45 · 2024: 46 · 2023: 47 · 2022: 33 · 2021: 42 · 2020: 39 · 2019: 30 · 2018: 18
- FWCI
- 4.61
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- World Journal of Gastroenterology (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion, cc-by-nc)
- Topics
- Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Keywords
- Mediterranean diet, non-alcoholic fatty liver disease, polyphenols, polyunsaturated fatty acids, carotenoids, anti-inflammatory activity, antioxidant activity, oxidative stress, inflammation, metabolic syndrome, cardiovascular risk, lifestyle intervention, pediatric NAFLD, pathogenesis
- MeSH terms
- Gastrointestinal Microbiome, Adult, Child, Humans, Life Style, Lipids, Liver, Patient Compliance, Risk Factors, Exercise, Treatment Outcome, Oxidative Stress, Diet, Mediterranean, Lipid Metabolism, Non-alcoholic Fatty Liver Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
