The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Measuring the Strength of Mice
Open accessAbstract
Kondziela devised the inverted screen test and published it in 1964. It is a test of muscle strength using all four limbs. Most normal mice easily score maximum on this task; it is a quick but insensitive gross screen, and the weights test described in this article will provide a finer measure of muscular strength. There are also several strain gauge-based pieces of apparatus available commercially that will provide more graded data than the inverted screen test, but their cost may put them beyond the reach of many laboratories which do not specialize in strength testing. Hence in 2000 a cheap and simple apparatus was devised by the author. It consists of a series of chain links of increasing length, attached to a "fur collector" a ball of fine wire mesh sold for preventing limescale build up in hard water areas. An accidental observation revealed that mice could grip these very tightly, so they proved ideal as a grip point for a weight-lifting apparatus. A common fault with commercial strength meters is that the bar or other grip feature is not thin enough for mice to exert a maximum grip. As a general rule, the thinner the wire or bar, the better a mouse can grip with its small claws. This is a pure test of strength, although as for any test motivational factors could potentially play a role. The use of scale collectors, however, seems to minimize motivational problems as the motivation appears to be very high for most normal young adult mice.
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Cites
X chromosome-linked muscular dystrophy (mdx) in the mouse
Bulfield, G., Siller, W. G., Wight, P. A., & Moore, K. J. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.4.1189 · Cited by 1,765
Hippocampal cytotoxic lesion effects on species-typical behaviours in mice
Deacon, R. M. J., Croucher, A., & Rawlins, J. N. P. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00401-6 · Cited by 304
Self-citationContet, C. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00231-5 · Cited by 176
Early behavioural changes in scrapie‐affected mice and the influence of dapsone
Guenther, K. M., Deacon, R. M. J., Perry, V. H., & Rawlins, J. N. P. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01645.x · Cited by 150
Self-citationBehavioral phenotyping of mice lacking the KATP channel subunit Kir6.2
Deacon, R. M. J., Brook, R. C., Meyer, D. H., Haeckel, O., Ashcroft, F. M., Miki, T., Seino, S., & Liss, B. (2006) · Physiology & Behavior · doi:10.1016/j.physbeh.2006.01.013 · Cited by 51
Self-citationA comparison of the behavior of C57BL/6 and C57BL/10 mice
Deacon, R. M. J., Thomas, C., Rawlins, J. N. P., & Morley, B. J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.02.009 · Cited by 46
Self-citation[A NEW METHOD FOR THE MEASUREMENT OF MUSCLE RELAXATION IN WHITE MICE].
Kondziella, W. (1964) · PubMed · Cited by 43
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Metadata
- Authors
- Deacon, R. M. J.
- Venue
- Journal of Visualized Experiments
- Publisher
- MyJove Corporation
- Published
- 2013-06-02
- Issue
- 76
- ISSN
- 1940-087X (ISSN-L)
- DOI
- 10.3791/2610
- OpenAlex
- W1982034065
- Cited by
- 281
- References
- 7
- FWCI
- 10.62
- Type
- journal article
- Language
- en
- Open access
- green
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