X chromosome-linked muscular dystrophy (mdx) in the mouse

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

LYON, M. F. (1961) · Nature · doi:10.1038/190372a0 · Cited by 3,978 · see citing works

Linkage relationship of a cloned DNA sequence on the short arm of the X chromosome to Duchenne muscular dystrophy

Murray, J., Davies, K. E., Harper, P. S., Meredith, L., Mueller, C. R., & Williamson, R. (1982) · Nature · doi:10.1038/300069a0 · Cited by 330 · see citing works

ACID HYDROLASES AS MODELS OF GENETIC CONTROL

Paigen, K. (1979) · Annual Review of Genetics · doi:10.1146/annurev.ge.13.120179.002221 · Cited by 233 · see citing works

Genetic linkage between Becker muscular dystrophy and a polymorphic DNA sequence on the short arm of the X chromosome.

Kingston, H. M., Thomas, N. S. T., Pearson, P. L., Sarfarazi, M., & Harper, P. S. (1983) · Journal of Medical Genetics · doi:10.1136/jmg.20.4.255 · Cited by 90 · see citing works

Chimaera mouse study shows absence of disease in genetically dystrophic muscle

Peterson, A. C. (1974) · Nature · doi:10.1038/248561a0 · Cited by 61 · see citing works

Serum pyruvate kinase in muscle disease and carrier states

Alberts, M. C., & Samaha, F. J. (1974) · Neurology · doi:10.1212/wnl.24.5.462 · Cited by 54 · see citing works

A histological study of muscle from the bar harbor strain of dystrophic mice

Pearce, G. W., & Walton, J. N. (1963) · The Journal of Pathology and Bacteriology · doi:10.1002/path.1700860105 · Cited by 51 · see citing works

Polymorphism of kidney pyruvate kinase in the mouse is determined by a gene, Pk-3, on chromosome 9

Peters, J., Nash, H., Eicher, E. M., & Bulfield, G. (1981) · Biochemical Genetics · doi:10.1007/bf00484007 · Cited by 46 · see citing works

Pyruvate kinase isoenzymes in progressive muscular dystrophy and in acute myocardial infarction

Harano, Y., Adair, R., Vignos, P. J., Miller, M., & Kowal, J. (1973) · Metabolism · doi:10.1016/0026-0495(73)90041-3 · Cited by 41 · see citing works

Creatine Phosphokinase Isoenzymes in Muscle in human Myopathies

Kar, N. C., & Pearson, C. M. (1965) · American Journal of Clinical Pathology · doi:10.1093/ajcp/43.3.207 · Cited by 40 · see citing works

INVOLVEMENT OF PERIPHERAL AND CENTRAL NERVES IN MURINE DYSTROPHY *

Bradley, W. G., & Jaros, E. (1979) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1979.tb56518.x · Cited by 37 · see citing works

ANIMAL MODELS: WHAT IS THEIR RELEVANCE TO THE PATHOGENESIS OF HUMAN MUSCULAR DYSTROPHY?

Harris, J. B., & Slater, C. R. (1980) · British Medical Bulletin · doi:10.1093/oxfordjournals.bmb.a071637 · Cited by 32 · see citing works

MUSCULAR DYSTROPHY IN THE MOUSE: NEUROMUSCULAR TRANSMISSION AND THE CONCEPT OF FUNCTIONAL DENERVATION *

Harris, J. B., & Ribchester, R. R. (1979) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1979.tb56522.x · Cited by 31 · see citing works

GENETIC VARIATION IN ACTIVITY OF THE ENZYMES OF GLYCOLYSIS AND GLUCONEOGENESIS BETWEEN INBRED STRAINS OF MICE

Bulfield, G., Moore, E. A., & KACSER, H. (1978) · Genetics · doi:10.1093/genetics/89.3.551 · Cited by 27 · see citing works

Semi-automated assays for enzymopathies of carbohydrate metabolism in liver and erythrocytes, using a reaction rate analyser

Bulfield, G., & Moore, E. A. (1974) · Clinica Chimica Acta · doi:10.1016/0009-8981(74)90108-9 · Cited by 27 · see citing works

Report of the committee on the genetic constitution of the X and Y chromosomes

Miller, O. J., & Siniscalco, M. (2008) · Cytogenetics and Cell Genetics · doi:10.1159/000131697 · Cited by 20 · see citing works

An allele (Pk-1 b ) from wild-caught mice that affects the activity and kinetics of erythrocyte and liver pyruvate kinase

Moore, K. J., & Bulfield, G. (1981) · Biochemical Genetics · doi:10.1007/bf00484008 · Cited by 16 · see citing works

Dystrophin: the protein product of the Duchenne muscular dystrophy locus

Hoffman, E. P., Brown, R. H., & Kunkel, L. M. (1987) · Cell · doi:10.1016/0092-8674(87)90579-4 · Cited by 4,693 · see citing works

The Molecular Basis of Muscular Dystrophy in the <i>mdx</i> Mouse: a Point Mutation

Sicinski, P., Geng, Y., Ryder-Cook, A. S., Barnard, E. A., Darlison, M. G., & Barnard, P. J. (1989) · Science · doi:10.1126/science.2662404 · Cited by 1,086 · see citing works

Function and Genetics of Dystrophin and Dystrophin-Related Proteins in Muscle

Blake, D. J., Weir, A., Newey, S. E., & Davies, K. E. (2002) · Physiological Reviews · doi:10.1152/physrev.00028.2001 · Cited by 1,231 · see citing works

Loss of a-Type Lamin Expression Compromises Nuclear Envelope Integrity Leading to Muscular Dystrophy

Sullivan, T. L., Escalante‐Alcalde, D., Bhatt, H., Anver, M. R., BHAT, N. K., Nagashima, K., Stewart, C. L., & Burke, B. E. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.5.913 · Cited by 1,197 · see citing works

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

Kole, R., Krainer, A. R., & Altman, S. (2012) · Nature Reviews Drug Discovery · doi:10.1038/nrd3625 · Cited by 1,152 · see citing works

Calcium Ion in Skeletal Muscle: Its Crucial Role for Muscle Function, Plasticity, and Disease

Berchtold, M. W., Brinkmeier, H., & Müntener, M. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.3.1215 · Cited by 1,007 · see citing works

Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy

Brenman, J. E., Chao, D. S., Xia, H., Aldape, K. D., & Bredt, D. S. (1995) · Cell · doi:10.1016/0092-8674(95)90471-9 · Cited by 953 · see citing works

Function of the myogenic regulatory factors Myf5, MyoD, Myogenin and MRF4 in skeletal muscle, satellite cells and regenerative myogenesis

Zammit, P. S. (2017) · Seminars in Cell &amp; Developmental Biology · doi:10.1016/j.semcdb.2017.11.011 · Cited by 887 · see citing works

Conversion of mdx myofibres from dystrophin-negative to -positive by injection of normal myoblasts

Partridge, T. A., Morgan, J. E., Coulton, G. R., Hoffman, E. P., & Kunkel, L. M. (1989) · Nature · doi:10.1038/337176a0 · Cited by 874 · see citing works

Functional improvement of dystrophic muscle by myostatin blockade

Bogdanovich, S., Krag, T. O. B., Barton, E. R., Morris, L. D., Whittemore, L.-A., Ahima, R. S., & Khurana, T. S. (2002) · Nature · doi:10.1038/nature01154 · Cited by 831 · see citing works

Utrophin–dystrophin-deficient mice as a model for Duchenne muscular dystrophy

Deconinck, A. E., Rafael, J. A., Skinner, J. A., Brown, S. C., Potter, A. C., Metzinger, L., Watt, D. J., Dickson, J. G., Tinsley, J. M., & Davies, K. E. (1997) · Cell · doi:10.1016/s0092-8674(00)80532-2 · Cited by 752 · see citing works

Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors

Lemos, D. R., Babaeijandaghi, F., Low, M., Chang, C.-K., Lee, S. T., Fiore, D., Zhang, R.-H., Natarajan, A., Nedospasov, S. A., & Rossi, F. M. V. (2015) · Nature Medicine · doi:10.1038/nm.3869 · Cited by 740 · see citing works

Prevention of muscular dystrophy in mice by CRISPR/Cas9–mediated editing of germline DNA

Long, C., McAnally, J. R., Shelton, J. M., Mireault, A. A., Bassel-Duby, R., & Olson, E. N. (2014) · Science · doi:10.1126/science.1254445 · Cited by 720 · see citing works

The molecular regulation of myogenesis

Sabourin, L. A., & Rudnicki, M. A. (2000) · Clinical Genetics · doi:10.1034/j.1399-0004.2000.570103.x · Cited by 720 · see citing works

The Skeletal Muscle Satellite Cell: The Stem Cell That Came in From the Cold

Zammit, P. S., Partridge, T. A., & Yablonka‐Reuveni, Z. (2006) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.6r6995.2006 · Cited by 684 · see citing works

Skeletal and Cardiac Myopathies in Mice Lacking Utrophin and Dystrophin: A Model for Duchenne Muscular Dystrophy

Grady, R. M., Teng, H., Nichol, M. C., Cunningham, J. M., Wilkinson, R. S., & Sanes, J. R. (1997) · Cell · doi:10.1016/s0092-8674(00)80533-4 · Cited by 639 · see citing works

Expression of full-length utrophin prevents muscular dystrophy in mdx mice

Tinsley, J. M., Deconinck, N., Fisher, R., Kahn, D., Phelps, S., Gillis, J., & Davies, K. E. (1998) · Nature Medicine · doi:10.1038/4033 · Cited by 608 · see citing works

A New Look at the Origin, Function, and “Stem-Cell” Status of Muscle Satellite Cells

Seale, P., & Rudnicki, M. A. (2000) · Developmental Biology · doi:10.1006/dbio.1999.9565 · Cited by 590 · see citing works

Fast muscle fibers are preferentially affected in Duchenne muscular dystrophy

Webster, C., Silberstein, L., Hays, A. P., & Blau, H. M. (1988) · Cell · doi:10.1016/0092-8674(88)90463-1 · Cited by 579 · see citing works

A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice

Wehling, M., Spencer, M. J., & Tidball, J. G. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.200105110 · Cited by 530 · see citing works

Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice

Sacco, A., Mourkioti, F., Tran, R., Choi, J., Llewellyn, M., Kraft, P., Shkreli, M., Delp, S., Pomerantz, J. H., Artandi, S. E., et al. (2010) · Cell · doi:10.1016/j.cell.2010.11.039 · Cited by 512 · see citing works

Dynamics of muscle fibre growth during postnatal mouse development

White, R. B., Biérinx, A.-S., Gnocchi, V. F., & Zammit, P. S. (2010) · BMC Developmental Biology · doi:10.1186/1471-213x-10-21 · Cited by 512 · see citing works

Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy

McGreevy, J. W., Hakim, C. H., McIntosh, M. A., & Duan, D. (2015) · Disease Models & Mechanisms · doi:10.1242/dmm.018424 · Cited by 504 · see citing works

Muscle stem cells in development, regeneration, and diseasePreprint

Shi, X., & Garry, D. J. (2006) · Genes & Development · doi:10.1101/gad.1419406 · Cited by 502 · see citing works

Animal models for muscular dystrophy show different patterns of sarcolemmal disruption

Straub, V., Rafael, J. A., Chamberlain, J. S., & Campbell, K. P. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.139.2.375 · Cited by 488 · see citing works

Small and large animal models in cardiac contraction research: advantages and disadvantages

Milani-Nejad, N., & Janssen, P. M. L. (2014) · Pharmacology &amp; Therapeutics · doi:10.1016/j.pharmthera.2013.10.007 · Cited by 484 · see citing works

Expression Profiling in the Muscular Dystrophies

Chen, Y., Zhao, P., Borup, R., & Hoffman, E. P. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.6.1321 · Cited by 481 · see citing works

Development of Approaches to Improve Cell Survival in Myoblast Transfer Therapy

Qu, Z., Balkir, L., van Deutekom, J. C. T., Robbins, P. D., Pruchnic, R., & Huard, J. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.5.1257 · Cited by 456 · see citing works

Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice

Ragot, T., Vincent, N., Chafey, P., Vigne, E., Gilgenkrantz, H., Coutont, D., Cartaud, J., Briand, P., Kaplant, J.-C., Perricaude, M., et al. (1993) · Nature · doi:10.1038/361647a0 · Cited by 454 · see citing works

Immunoelectron microscopic localization of dystrophin in myofibres

Watkins, S. C., Hoffman, E. P., Slayter, H. S., & Kunkel, L. M. (1988) · Nature · doi:10.1038/333863a0 · Cited by 447 · see citing works

Recruitment of bone-marrow-derived cells by skeletal and cardiac muscle in adult dystrophic mdx mice

Bittner, R. E., Schöfer, C., Weipoltshammer, K., Ivanova, S., Streubel, B., Hauser, E., Freilinger, M., Höger, H., Elbe‐Bürger, A., & Wachtler, F. J. (1999) · Anatomy and Embryology · doi:10.1007/s004290050237 · Cited by 441 · see citing works

Muscular dystrophies involving the dystrophin–glycoprotein complex: an overview of current mouse models

Durbeej, M., & Campbell, K. P. (2002) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(02)00309-x · Cited by 434 · see citing works

The homologue of the Duchenne locus is defective in X-linked muscular dystrophy of dogs

Cooper, B. J., Winand, N. J., Stedman, H., Valentine, B. A., Hoffman, E. P., Kunkel, L. M., Scott, M.-O., Fischbeck, K. H., Kornegay, J. N., Avery, R. J., et al. (1988) · Nature · doi:10.1038/334154a0 · Cited by 428 · see citing works

Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca 2+ , Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy

Allen, D. G., Whitehead, N. P., & Froehner, S. C. (2015) · Physiological Reviews · doi:10.1152/physrev.00007.2015 · Cited by 422 · see citing works

Localization of dystrophin to postsynaptic regions of central nervous system cortical neurons

Lidov, H. G. W., Byers, T. J., Watkins, S. C., & Kunkel, L. M. (1990) · Nature · doi:10.1038/348725a0 · Cited by 421 · see citing works

Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice.

Ohlendieck, K., & Campbell, K. P. (1991) · The Journal of Cell Biology · doi:10.1083/jcb.115.6.1685 · Cited by 420 · see citing works

Histological parameters for the quantitative assessment of muscular dystrophy in the mdx-mouse

Briguet, A., Courdier-Fruh, I., Foster, M., Meier, T., & Magyar, J. P. (2004) · Neuromuscular Disorders · doi:10.1016/j.nmd.2004.06.008 · Cited by 417 · see citing works

Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse

Mann, C. J., Honeyman, K., Cheng, A. J., Ly, T., Lloyd, F., Fletcher, S., Morgan, J. E., Partridge, T. A., & Wilton, S. D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.1.42 · Cited by 406 · see citing works

mdx mice show progressive weakness and muscle deterioration with age

Pastoret, C., & Sébille, A. (1995) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(94)00276-t · Cited by 402 · see citing works

Calcium entry through stretch-inactivated ion channels in mdx myotubes

Franco‐Obregón, A., & Lansman, J. B. (1990) · Nature · doi:10.1038/344670a0 · Cited by 397 · see citing works

Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy

Lai, Y., Thomas, G. D., Yue, Y., Yang, H. T., Li, D., Long, C., Judge, L. M., Bostick, B., Chamberlain, J. S., Terjung, R. L., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci36612 · Cited by 383 · see citing works

Neuronal nitric oxide synthase and dystrophin-deficient muscular dystrophy.

Chang, W. J., Iannaccone, S. T., Lau, K. S., Masters, B. S. S., McCabe, T. J., McMillan, K., Padre, R. C., Spencer, M. J., Tidball, J. G., & Stull, J. T. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.17.9142 · Cited by 367 · see citing works

Impaired metabolic modulation of α-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle

Thomas, G. D., Sander, M., Lau, K. S., Huang, P. L., Stull, J. T., & Victor, R. G. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.15090 · Cited by 366 · see citing works

PGC-1α regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophyPreprint

Handschin, C., Kobayashi, Y. M., Chin, S., Seale, P., Campbell, K. P., & Spiegelman, B. M. (2007) · Genes & Development · doi:10.1101/gad.1525107 · Cited by 355 · see citing works

Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathy

Reddy, S., Smith, D. B. J., Rich, M. M., Leferovich, J. M., Reilly, P., Davis, B. M., Tran, K., Rayburn, H., Bronson, R. T., Cros, D. P., et al. (1996) · Nature Genetics · doi:10.1038/ng0796-325 · Cited by 352 · see citing works

Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy

Grounds, M. D., Radley‐Crabb, H. G., Lynch, G. S., Nagaraju, K., & Luca, A. D. (2008) · Neurobiology of Disease · doi:10.1016/j.nbd.2008.03.008 · Cited by 342 · see citing works

THE mdx MOUSE SKELETAL MUSCLE MYOPATHY: I. A HISTOLOGICAL, MORPHOMETRIC AND BIOCHEMICAL INVESTIGATION

Coulton, G. R., Morgan, J. E., Partridge, T. A., & Sloper, J. C. (1988) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1988.tb00866.x · Cited by 340 · see citing works

Skeletal muscle pathology in X chromosome-linked muscular dystrophy (mdx) mouse

Tanabe, Y., Esaki, K., & Nomura, T. (1986) · Acta Neuropathologica · doi:10.1007/bf00687043 · Cited by 329 · see citing works

Dystrophin‐deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma

Chamberlain, J. S., Metzger, J. M., Reyes, M., Townsend, D., & Faulkner, J. A. (2007) · The FASEB Journal · doi:10.1096/fj.06-7353com · Cited by 328 · see citing works

Dystrophin abnormalities in Duchenne/Becker muscular dystrophy

Hoffman, E. P., & Kunkel, L. M. (1989) · Neuron · doi:10.1016/0896-6273(89)90226-2 · Cited by 328 · see citing works

Decreased osmotic stability of dystrophin-less muscle cells from the mdx mouse

Menke, A., & Jockusch, H. (1991) · Nature · doi:10.1038/349069a0 · Cited by 327 · see citing works

The fate of individual myoblasts after transplantation into muscles of DMD patients

Gussoni, E., Blau, H. M., & Kunkel, L. M. (1997) · Nature Medicine · doi:10.1038/nm0997-970 · Cited by 326 · see citing works

Regulatory factors and cell populations involved in skeletal muscle regeneration

Broek, R. W. T., Grefte, S., & den Hoff, J. W. V. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22127 · Cited by 315 · see citing works

MyoD−/− Satellite Cells in Single-Fiber Culture Are Differentiation Defective and MRF4 Deficient

Cornelison, D., Olwin, B. B., Rudnicki, M. A., & Wold, B. J. (2000) · Developmental Biology · doi:10.1006/dbio.2000.9682 · Cited by 314 · see citing works

Expression of Matrix Metalloproteinases 2 and 9 in Regenerating Skeletal Muscle: A Study in Experimentally Injured andmdxMuscles

Kherif, S. A. A. B., Lafuma, C., Dehaupas, M., Lachkar, S., Fournier, J. G., Verdière‐Sahuqué, M., Fardeau, M., & Alameddine, H. S. (1999) · Developmental Biology · doi:10.1006/dbio.1998.9107 · Cited by 312 · see citing works

Brain function in Duchenne muscular dystrophy

Anderson, J. L., Head, S. I., Rae, C. D., & Morley, J. W. (2002) · Brain · doi:10.1093/brain/awf012 · Cited by 310 · see citing works

Force and power output of fast and slow skeletal muscles from mdx mice 6‐28 months old

Lynch, G. S., Hinkle, R. T., Chamberlain, J. S., Brooks, S. V., & Faulkner, J. A. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.00591.x · Cited by 305 · see citing works

Overview of the Muscle Cytoskeleton

Henderson, C. A., Gomez, C. G., Novak, S. M., Mi‐Mi, L., & Gregorio, C. C. (2017) · Comprehensive physiology · doi:10.1002/cphy.c160033 · Cited by 305 · see citing works

Gutless adenovirus: last-generation adenovirus for gene therapy

Alba, R., Bosch, A., & Chillón, M. (2005) · Gene Therapy · doi:10.1038/sj.gt.3302612 · Cited by 303 · see citing works

rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice

Gregorevic, P., Allen, J. M., Minami, E., Blankinship, M. J., Haraguchi, M., Meuse, L. A., Finn, E. E., Adams, M. E., Froehner, S. C., Murry, C. E., et al. (2006) · Nature Medicine · doi:10.1038/nm1439 · Cited by 303 · see citing works

Measuring the Strength of Mice

Deacon, R. M. J. (2013) · Journal of Visualized Experiments · doi:10.3791/2610 · Cited by 298 · see citing works

The Pathogenesis and Therapy of Muscular Dystrophies

Guiraud, S., Aartsma-Rus, A. M., Vieira, N. M., Davies, K. E., van Ommen, G. B., & Kunkel, L. M. (2015) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-090314-025003 · Cited by 297 · see citing works

Skeletal muscle mitochondrial remodeling in exercise and diseases

Gan, Z., Fu, T., Kelly, D. P., & Vega, R. B. (2018) · Cell Research · doi:10.1038/s41422-018-0078-7 · Cited by 287 · see citing works

Muscular dystrophy in the mdx mouse: Histopathology of the soleus and extensor digitorum longus muscles

Carnwath, J. W., & Shotton, D. M. (1987) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(87)90219-x · Cited by 286 · see citing works

Early onset of inflammation and later involvement of TGFβ in Duchenne muscular dystrophy

Chen, Y. W., Nagaraju, K., Bakay, M. A., McIntyre, O., Rawat, R., Shi, R., & Hoffman, E. P. (2005) · Neurology · doi:10.1212/01.wnl.0000173836.09176.c4 · Cited by 278 · see citing works

An adult tissue-specific stem cell in its niche: A gene profiling analysis of in vivo quiescent and activated muscle satellite cells

Pallafacchina, G., François, S., Regnault, B., Czarny, B., Dive, V., Cumano, A., Montarras, D., & BUCKINGHAM, M. E. (2009) · Stem Cell Research · doi:10.1016/j.scr.2009.10.003 · Cited by 278 · see citing works

Somatic reversion/suppression of the mouse mdx phenotype in vivo

Hoffman, E. P., Morgan, J. E., Watkins, S. C., & Partridge, T. A. (1990) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(90)90195-s · Cited by 276 · see citing works

Increased calcium influx in dystrophic muscle.

Turner, P. R., Fong, P. Y., Denetclaw, W. F., & Steinhardt, R. A. (1991) · The Journal of Cell Biology · doi:10.1083/jcb.115.6.1701 · Cited by 273 · see citing works

Enhanced Expression of the α7β1 Integrin Reduces Muscular Dystrophy and Restores Viability in Dystrophic Mice

Burkin, D. J., Wallace, G. Q., Nicol, K. J., Kaufman, D., & Kaufman, S. J. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.6.1207 · Cited by 269 · see citing works

Quantitation of central activation failure during maximal voluntary contractions in humans

Kent‐Braun, J. A., & Blanc, R. L. (1996) · Muscle & Nerve · doi:10.1002/(sici)1097-4598(199607)19:7 · Cited by 380 · see citing works

Fibroblast Growth Factor in the Extracellular Matrix of Dystrophic (mdx) Mouse Muscle

DiMario, J. X., Buffinger, N., Yamada, S., & Strohman, R. C. (1989) · Science · doi:10.1126/science.2717945 · Cited by 262 · see citing works

Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis

Kopinke, D., Roberson, E. C., & Reiter, J. F. (2017) · Cell · doi:10.1016/j.cell.2017.06.035 · Cited by 260 · see citing works

Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiationPreprint

Frock, R. L., Kudlow, B. A., Evans, A. M., Jameson, S. A., Hauschka, S. D., & Kennedy, B. K. (2006) · Genes & Development · doi:10.1101/gad.1364906 · Cited by 256 · see citing works

Regulatory T cells suppress muscle inflammation and injury in muscular dystrophy

Villalta, S. A., Rosenthal, W. L., Martinez, L., Kaur, A., Sparwasser, T. D., Tidball, J. G., Margeta, M., Spencer, M. J., & Bluestone, J. A. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009925 · Cited by 253 · see citing works

Defective muscle basement membrane and lack of M-laminin in the dystrophic dy/dy mouse.

Xu, H. W., Christmas, P., Wu, X., Wewer, U. M., & Engvall, E. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.12.5572 · Cited by 252 · see citing works

Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells

Wu, Y., Zhou, H., Fan, X., Zhang, Y., Zhang, M., Wang, Y., Xie, Z., Bai, M., Yin, Q., Liang, D., et al. (2015) · Cell Research · doi:10.1038/cr.2014.160 · Cited by 247 · see citing works

Delivery of therapeutic oligonucleotides with cell penetrating peptides

Boisguérin, P., Deshayes, S., Gait, M. J., O’Donovan, L., Godfrey, C., Betts, C., Wood, M. J. A., & Lebleu, B. (2015) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.02.008 · Cited by 245 · see citing works

CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice

Xu, L., Park, K. H., Zhao, L., Xu, J., El Refaey, M., Gao, Y., Zhu, H., Ma, J., & Han, R. (2016) · Molecular Therapy · doi:10.1038/mt.2015.192 · Cited by 244 · see citing works

Targeting β1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice

Rozo, M., Li, L., & Fan, C. (2016) · Nature Medicine · doi:10.1038/nm.4116 · Cited by 244 · see citing works

Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells

Earle, A., Kirby, T. J., Fedorchak, G. R., Isermann, P., Patel, J., Iruvanti, S., Moore, S. A., Bonne, G., Wallrath, L. L., & Lammerding, J. (2019) · Nature Materials · doi:10.1038/s41563-019-0563-5 · Cited by 243 · see citing works

Normal myogenic cells from newborn mice restore normal histology to degenerating muscles of the mdx mouse.

Morgan, J. E., Hoffman, E. P., & Partridge, T. A. (1990) · The Journal of Cell Biology · doi:10.1083/jcb.111.6.2437 · Cited by 242 · see citing works

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9

Chen, Y., Zheng, Y., Kang, Y., Yang, W., Niu, Y., Guo, X., Tu, Z., Si, C., Wang, H., Xing, R., et al. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddv120 · Cited by 241 · see citing works

Myostatin propeptide‐mediated amelioration of dystrophic pathophysiology

Bogdanovich, S., Perkins, K. J., Krag, T. O. B., Whittemore, L.-A., & Khurana, T. S. (2005) · The FASEB Journal · doi:10.1096/fj.04-2796com · Cited by 240 · see citing works

Deletion of Murine SMN Exon 7 Directed to Skeletal Muscle Leads to Severe Muscular Dystrophy

Cifuentes-Díaz, C., Frugier, T., Tiziano, F. D., Lacène, E., Roblot, N., Joshi, V., Moreau, M. H., & Melki, J. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.5.1107 · Cited by 236 · see citing works

Apoptosis precedes necrosis of dystrophin-deficient muscle

Tidball, J. G., Albrecht, D. E., Lokensgard, B., & Spencer, M. J. (1995) · Journal of Cell Science · doi:10.1242/jcs.108.6.2197 · Cited by 234 · see citing works

Dystrophin colocalizes with beta-spectrin in distinct subsarcolemmal domains in mammalian skeletal muscle

Porter, G. A., Dmytrenko, G. M., Winkelmann, J., & Bloch, R. (1992) · The Journal of Cell Biology · doi:10.1083/jcb.117.5.997 · Cited by 231 · see citing works

Recovery of induced mutations for X chromosome-linked muscular dystrophy in mice.

Chapman, V. M., Miller, D. R., Armstrong, D., & Caskey, C. T. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.4.1292 · Cited by 227 · see citing works

Pharmacological strategies for muscular dystrophy

Khurana, T. S., & Davies, K. E. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1085 · Cited by 225 · see citing works

SMASH – semi-automatic muscle analysis using segmentation of histology: a MATLAB application

Smith, L., & Barton, E. R. (2014) · Skeletal Muscle · doi:10.1186/2044-5040-4-21 · Cited by 223 · see citing works

Cell and fiber type distribution of dystrophin

Hoffman, E. P., Hudecki, M. S., Rosenberg, P. A., Pollina, C. M., & Kunkel, L. M. (1988) · Neuron · doi:10.1016/0896-6273(88)90191-2 · Cited by 218 · see citing works

Postsynaptic Abnormalities at the Neuromuscular Junctions of Utrophin-deficient Mice

Deconinck, A. E., Potter, A. C., Tinsley, J. M., Wood, S. J., Vater, R., Young, C., Metzinger, L., Vincent, A. C., Slater, C. R., & Davies, K. E. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.136.4.883 · Cited by 218 · see citing works

Muscle satellite cells are a functionally heterogeneous population in both somite-derived and branchiomeric muscles

Ono, Y., Boldrin, L., Knopp, P., Morgan, J. E., & Zammit, P. S. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.10.005 · Cited by 217 · see citing works

Invited review: Myoblast transfer: A possible therapy for inherited myopathies?

Partridge, T. A. (1991) · Muscle & Nerve · doi:10.1002/mus.880140302 · Cited by 217 · see citing works

Assessing Functional Performance in the Mdx Mouse Model

Aartsma-Rus, A. M., & van Putten, M. (2014) · Journal of Visualized Experiments · doi:10.3791/51303 · Cited by 216 · see citing works

Dystrophin is expressed in mdx skeletal muscle fibers after normal myoblast implantation.

Karpati, G., Pouliot, Y., Zubrzycka‐Gaarn, E. E., Carpenter, S., Ray, P. N., Worton, R. G., & Holland, P. C. (1989) · Europe PMC (PubMed Central) · Cited by 216 · see citing works

The role of aquaporin-4 in the blood–brain barrier development and integrity: Studies in animal and cell culture models

Nicchia, G. P., Nico, B., Camassa, L. M. A., Mola, M. G., Loh, N., Dermietzel, R., Spray, D. C., Svelto, M., & Frigeri, A. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.07.055 · Cited by 216 · see citing works

Small‐caliber skeletal muscle fibers do not suffer necrosis in mdx mouse dystrophy

Karpati, G., Carpenter, S., & Prescott, S. (1988) · Muscle & Nerve · doi:10.1002/mus.880110802 · Cited by 214 · see citing works

Specific removal of the nonsense mutation from the mdx dystrophin mRNA using antisense oligonucleotides

Wilton, S. D., Lloyd, F., Carville, K. S., Fletcher, S., Honeyman, K., Agrawal, S., & Kole, R. (1999) · Neuromuscular Disorders · doi:10.1016/s0960-8966(99)00010-3 · Cited by 214 · see citing works

Chromosome maps of man and mouse. IV

Searle, A. G., Peters, J., Lyon, M. F., Hall, J. G., Evans, E. P., Edwards, J. H., & Buckle, V. J. (1989) · Annals of Human Genetics · doi:10.1111/j.1469-1809.1989.tb01777.x · Cited by 213 · see citing works

Differential expression of dystrophin isoforms in strains of mdx mice with different mutations

Im, W. B. (1996) · Human Molecular Genetics · doi:10.1093/hmg/5.8.1149 · Cited by 212 · see citing works

trophy (mdx) in the mouse

Bulfield, G., Wg, S., Wight, P. A. L., & MOOREt, K. J. (2016)

Recovery of induced mutations for X chromosome-linked muscular dystrophy in mice.

Chapman, V. M., Miller, D. R., Armstrong, D., & Caskey, C. T. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.4.1292 · Cited by 227 · see citing works

X Chromosome-Linked Muscular Dystrophy (mdx) of the Skeletal Muscle, Mouse

Tanabe, Y., Woo, M., & Nonaka, I. (1991) · Monographs on pathology of laboratory animals · doi:10.1007/978-3-642-76533-9_22 · Cited by 2 · see citing works

The mapping of a cDNA from the human X-linked Duchenne muscular dystrophy gene to the mouse X chromosome

Brockdorff, N., Cross, G. S., Cavanna, J., Fisher, E., Lyon, M. F., Davies, K. E., & Brown, S. D. M. (1987) · Nature · doi:10.1038/328166a0 · Cited by 66 · see citing works

Localization of the region homologous to the Duchenne muscular dystrophy locus on the mouse X chromosome

Heilig, R., Lemaire‐Vieille, C., Mandel, J., Dandolo, L., Amar, L., & Avner, P. R. (1987) · Nature · doi:10.1038/328168a0 · Cited by 53 · see citing works