Effects of Malaria in pregnancy on newborn anthropometry
Open accessAbstract
Background: Malaria in pregnancy remains a major cause of infant mortality through its contribution to preterm delivery, low birth weight and intrauterine death. Methodology: During a cross-sectional study of 983 mothers delivering in a secondary health care facility in Ibadan, southwestern Nigeria, an area of high malaria transmission, the effect of maternal and placental malaria parasitaemia on newborn anthropometry was evaluated. Malaria parasitemia was detected by microscopy of Giemsa stained thick blood smears. Results: Placental, maternal and combined placental and maternal malaria parasitaemia rates at the time of delivery were 13.1%, 12.7% and 11.1% respectively. The geometric mean parasite densities in maternal and placental smears were significantly higher in primigravid mothers than others (p = 0.004 and 0.002 respectively). Low birth weight rate was higher among babies born to mothers with maternal parasitaemia compared to those without (8.0 % versus 6.3%, p < 0.05). The mean birth weight was lower in neonates of mothers with peripheral and placental parasitaemia by 138 g and 122 g (p = 0.01 and 0.02) respectively, while the respective difference was up to 168 g and 151 g among primigravidae (p = 0.03 and 0.04). Neonates of mothers with maternal and placental parasitaemia had a lower mean length than those without parasitaemia (48.2 vs 49.2cm, p = < 0.0001 and 48.5 vs 49.2cm p = 0.02 respectively). Occiptofrontal circumference and ponderal indices were not significantly affected by maternal malaria parasitaemia. Conclusion: Malaria in pregnancy results in symmetric foetal growth restriction and the effect is more marked among primigravid mothers.
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Several meta-analyses support the finding that the overall odds of anaemia are higher among pregnant women with malaria.
“Several meta-analyses support our findings as the overall odds of malaria of anaemia are higher amongst pregnant women with malaria [24].”
From Malaria in pregnancy: Meta-analyses of prevalence and associated complications (2024) · cites this paper as [24]
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“Many other studies also observed that the mother’s age and parity are risk factors for placental malaria (Falade et al., 2010; Ndeserua et al., 2015; Ojurongbe et al., 2010; Tako et al., 2005; Walker et al., 2013), which is in contrast with our previously published results (Adam et al., 2005a; Adam…”
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Cord blood malaria parasitaemia in term, normal birthweight Nigerian babies
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- Authors
- Falade, C. O., Tongo, O. O., Ogunkunle, O. O., & Orimadegun, A. E.
- Affiliations
- University of Ibadan (NG)
- Venue
- The Journal of Infection in Developing Countries
- Published
- 2010-05-09
- Volume
- 4
- Issue
- 07
- Pages
- 448-453
- ISSN
- 1972-2680 (ISSN-L)
- OpenAlex
- W2032913785
- Cited by
- 46
- References
- 14
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 3 · 2022: 5 · 2021: 5 · 2020: 1 · 2019: 2 · 2018: 8 · 2017: 4 · 2016: 1 · 2015: 1 · 2014: 5 · 2013: 3 · 2012: 2
- FWCI
- 2.54
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- The Journal of Infection in Developing Countries (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- United States Agency for International Development
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Global Maternal and Child Health
- Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
- Keywords
- malaria in pregnancy, placental malaria, neonatal anthropometry, low birth weight, birth length, fetal growth restriction, primigravida, parasite density
- MeSH terms
- Adolescent, Adult, Anthropometry, Cross-Sectional Studies, Female, Fetal Growth Retardation, Humans, Infant, Newborn, Malaria, Microscopy, Middle Aged, Nigeria, Parasitology, Pregnancy, Pregnancy Complications, Infectious, Parasitemia, Young Adult
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