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Cited by 319

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

Late side effects of radiation treatment for head and neck cancer

Open access
Brook, Itzhak·2020·Radiation Oncology Journal

Abstract

Patients undergoing radiation therapy for head and neck cancer (HNC) experience significant early and long-term side effects. The likelihood and severity of complications depends on a number of factors, including the total dose of radiation delivered, over what time it was delivered and what parts of the head and neck received radiation. Late side effects include: permanent loss of saliva; osteoradionecrosis; radiation recall myositis, pharyngoesophageal stenosis; dental caries; oral cavity necrosis; fibrosis; impaired wound healing; skin changes and skin cancer; lymphedema; hypothyroidism, hyperparathyroidism, lightheadedness, dizziness and headaches; secondary cancer; and eye, ear, neurological and neck structures damage. Patients who undergo radiotherapy for nasopharyngeal carcinoma tend to suffer from chronic sinusitis. These side effects present difficult challenges to the patients and their caregivers and require life-long strategies to alleviate their deleterious effect on basic life functions and on the quality of life. This review presents these side effects and their management.

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Metadata

Authors
Brook, I.
Venue
Radiation Oncology Journal
Published
2020-06-30
Volume
38
Issue
2
Pages
84-92
ISSN
  • 1229-8719 (ISSN-L)
  • 2234-1900
  • 2234-3156
OpenAlex
W3036562742
Cited by
319
References
23
FWCI
11.57
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Late side effects of radiation treatment for head and neck cancer. https://app.cochat.ai/papers/10.3857/roj.2020.00213
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Brook, I. (2020). Late side effects of radiation treatment for head and neck cancer. Radiation Oncology Journal. https://doi.org/10.3857/roj.2020.00213

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.