Ginsenoside Rg1 Prevents Starvation-Induced Muscle Protein Degradation Via Regulation of AKT/mTOR/FoxO Signaling in C2C12 Myotubes

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The Administration of Panax Ginseng Berry Extract Attenuates High-Fat-Diet-Induced Sarcopenic Obesity in C57BL/6 Mice

Shin, J., Jeon, S.-H., Lee, S. J., & Choung, S. (2022) · Nutrients · doi:10.3390/nu14091747 · Cited by 23 · see citing works

Astragalus membranaceus Enhances Myotube Hypertrophy through PI3K-Mediated Akt/mTOR Signaling Phosphorylation

Yeh, T., Lei, T., Liu, J., & Hsu, M. (2022) · Nutrients · doi:10.3390/nu14081670 · Cited by 21 · see citing works

Therapeutic applications of ginseng for skeletal muscle-related disorder management

Ahmad, S. S., Chun, H. J., Ahmad, K., & Choi, I. (2023) · Journal of Ginseng Research · doi:10.1016/j.jgr.2023.06.003 · Cited by 20 · see citing works

Lactobacillus curvatus CP2998 Prevents Dexamethasone-Induced Muscle Atrophy in C2C12 Myotubes

KATSUKI, R., SAKATA, S., Nakao, R., Oishi, K., & Nakamura, Y. (2019) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.65.455 · Cited by 20 · see citing works

Natural constituents from food sources: potential therapeutic agents against muscle wasting

Shen, S., Yu, H., Gan, L., Yang, Y., & Lin, L. (2019) · Food & Function · doi:10.1039/c9fo00912d · Cited by 20 · see citing works

Identification of Withania somnifera-Silybum marianum-Trigonella foenum-graecum Formulation as a Nutritional Supplement to Contrast Muscle Atrophy and Sarcopenia

Salvadori, L., Mandrone, M., Manenti, T., Ercolani, C., Cornioli, L., Lianza, M., Tomasi, P., Chiappalupi, S., Filippo, E. S. D., Fulle, S., et al. (2020) · Nutrients · doi:10.3390/nu13010049 · Cited by 15 · see citing works

Expression patterns of regulatory lncRNAs and miRNAs in muscular atrophy models induced by starvation in vitro and in vivo

Lei, S., She, Y., Zeng, J., Chen, R., Zhou, S., & Shi, H. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.10661 · Cited by 14 · see citing works

Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro

Yakabe, M., Hosoi, T., Sasakawa, H., Akishita, M., & Ogawa, S. (2022) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-022-03812-w · Cited by 12 · see citing works

A Review of Complementary and Alternative Medicine Therapies on Muscular Atrophy: A Literature Review of In Vivo/In Vitro Studies

Jeong, S.-M., Seo, B.-K., Park, Y., & Baek, Y.-H. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/8654719 · Cited by 12 · see citing works

The potential of traditional herbal active ingredients in the treatment of sarcopenia animal models: focus on therapeutic effects and mechanisms

Ding, K., Jiang, W., Zhangwang, J., Wang, Y., Zhang, J., & Lei, M. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02639-7 · Cited by 11 · see citing works

Exploring the potential of ginseng-derived compounds in treating cancer cachexia

Ho, P. T. B., Rini, I. A., Hoang, P. T., Lee, T., & Lee, S. (2025) · Journal of Ginseng Research · doi:10.1016/j.jgr.2025.08.002 · Cited by 10 · see citing works

Panax notoginseng saponins promotes cerebral recovery from ischemic injury by downregulating LINGO-1 and activating the EGFR/PI3K/AKT signaling pathways in vivo

Yang, T., Guo, Q., Shi, X., Wu, S., Li, Y., Sun, Y., Zhao, Y., Chai, L., Gao, Y., Lou, L., et al. (2018) · Journal of Traditional Chinese Medical Sciences · doi:10.1016/j.jtcms.2018.03.009 · Cited by 7 · see citing works

Data-Independent Acquisition Method for In-Depth Proteomic Screening of Donkey Meat

Wang, L., Qu, H., Wang, X., Wang, T., Ma, Q., Khan, M. Z., Zhu, M., Wang, C., Liu, W., & Chai, W. (2024) · Agriculture · doi:10.3390/agriculture14122102 · Cited by 6 · see citing works

Korean red ginseng suppresses mitochondrial apoptotic pathway in denervation-induced skeletal muscle atrophy

Jeong, J.-S., Kim, J., Kim, J., Kim, C.-Y., Ko, J., & Kim, T. (2023) · Journal of Ginseng Research · doi:10.1016/j.jgr.2023.07.002 · Cited by 6 · see citing works

Glucose, glutamine, lactic acid and α‑ketoglutarate restore metabolic disturbances and atrophic changes in energy‑deprived muscle cells

Ikeda, M., Matsumoto, M., Tamura, M., Kobayashi, M., & Iida, K. (2025) · Molecular Medicine Reports · doi:10.3892/mmr.2025.13562 · Cited by 4 · see citing works

Transcriptome and Methylome Profiling in Rat Skeletal Muscle: Impact of Post-Weaning Protein Restriction

Ma, S., Hasegawa, E., Nakai, Y., Jia, H., & Kato, H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232415771 · Cited by 1 · see citing works

Bangle (Zingiber purpureum Rosc.) extract alleviates skeletal muscle atrophy through modulating Akt/FoxO1/NFκB pathway and enhancing mitochondrial biogenesis in a mouse colitis model

Kasai, S., Kato, M., & Sato, S. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107274 · Cited by 1 · see citing works

Inhibitory Effect of the Glycerophosphate Moiety of Lipoteichoic Acid from Lactic Acid Bacteria on Dexamethasone-Induced Atrogin-1 Expression in C2C12 Myotubes

KATSUKI, R., Shiraishi, T., SAKATA, S., Hirota, T., Nakamura, Y., & Yokota, S. (2021) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.67.351 · Cited by 1 · see citing works

Ginsenoside Rg1 attenuates arsenic-induced mice nephrotoxicity via the activated HO-1/mTOR-associated apoptosis or autophagy signalingPreprint

Yang, Y. (2021) · doi:10.14293/s2199-1006.1.sor-.ppsygzi.v1 · Cited by 1 · see citing works

Additional file 1 of Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro

Yakabe, M., Hosoi, T., Sasakawa, H., Akishita, M., & Ogawa, S. (2023) · Figshare · doi:10.6084/m9.figshare.22604452

Ninjin-yoei-to improves survival and attenuates cachexia by preserving muscle and body weight in murine models of lung cancer and fibrosis

Shigekusa, T., Tsubouchi, H., Yanagi, S., Sakai, K., Honda, M., Inomata, R., Miyazaki, T., & Nakazato, M. (2026) · Heliyon · doi:10.1016/j.heliyon.2026.e44532

Therapeutic potential of ginseng and ginsenosides on muscle wasting disorders: Cachexia, sarcopenia, anorexia, and aging

Bae, C., Muthamil, S., Lyu, J. H., Oh, J. M., Shin, U. C., Sihombing, M. A. E. M., Nguyen, T. Q. D., Kim, S.-W., Kim, J., Azim, M. M. N., et al. (2026) · Journal of Ginseng Research · doi:10.1016/j.jgr.2026.101021

The role of ginsenosides in obesity-associated sarcopenia: Focus on E3 ubiquitin ligase-mediated regulation of protein homeostasis

Zhou, W., Li, P.-T., Li, H.-Y., & Li, W. (2026) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2026.179200

Potential Molecular Mechanisms of Ginsenosides for Alleviating Cancer-Related Fatigue and Clinical Research Progress of Ginseng Preparations: A Review

Guo, J., Feng, Q., Shen, K., Cheng, J., Zhu, Y., Luan, Y., Gao, J., Zhu, S., Huang, F., Zhang, N., et al. (2026) · Molecules · doi:10.3390/molecules31213917

Ginsenoside Rg5 promotes muscle regeneration via p38MAPK and Akt/mTOR signaling

Kim, R., Kim, J. W., Choi, H., Oh, J., Kim, T. H., Go, G.-Y., Lee, S.-J., & Bae, G. (2023) · Journal of Ginseng Research · doi:10.1016/j.jgr.2023.06.004 · Cited by 21 · see citing works

Ginsenoside Rg1 Attenuates Muscle Atrophy in Hyperglycemic Conditions, Inactivity and Protein Deprivation Models via AKT/mTOR Pathway Activation

He, X., Li, Y., Chen, J., Zhang, L., Huang, Y., Zhou, Y., & Li, J. (2025) · Current Molecular Medicine · doi:10.2174/0115665240355315250414051525 · Cited by 1 · see citing works

Ginsenoside Rg1 from Panax ginseng enhances myoblast differentiation and myotube growth

Go, G.-Y., Lee, S.-J., Jo, A., Lee, J., Seo, D. W., Kang, J., Kim, S., Kim, S., Kim, Y. K., & Bae, G. (2017) · Journal of Ginseng Research · doi:10.1016/j.jgr.2017.05.006 · Cited by 30 · see citing works

Ubiquitin E3 ligase Atrogin-1 protein is regulated via the rapamycin-sensitive mTOR-S6K1 signaling pathway in C2C12 muscle cells

Nishimura, Y., Chunthorng-Orn, J., Lord, S., Musa, I., Dawson, P., Holm, L., & Lai, Y.-C. (2022) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00384.2021 · Cited by 23 · see citing works

20(S)-ginsenoside Rg3 promotes myoblast differentiation and protects against myotube atrophy via regulation of the Akt/mTOR/FoxO3 pathway

Wang, M., Ren, J., Chen, X., Liu, J., Xu, X., Li, X., Zhao, D., & Sun, L. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.114145 · Cited by 26 · see citing works