The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Isolation of extracellular vesicles: Determining the correct approach (Review)
Open accessAbstract
The discovery of extracellular vesicles (EVs) has revised the interpretation of intercellular communication. It is now well established that EVs play a significant role in coagulation, inflammation, cancer and stem cell renewal and expansion. Their release presents an intriguing, transporting/trafficking network of biologically active molecules, which are able to reach and modulate the function/behavior of the target cells in a variety of ways. Moreover, the presence of EVs in various body fluids points to their potential for use as biomarkers and prognostic indicators in the surveillance/monitoring of a variety of diseases. Although vast knowledge on the subject of EVs has accumulated over the years, there are still fundamental issues associated with the correct approach for their isolation. This review comprises the knowledge on EV isolation techniques that are currently available. The aim of this reveiw was to make both experienced researchers and newcomers to the field aware that different types of EVs require unique isolation approaches. The realization of this 'uniqueness' is the first step in the right direction for the complete assessment of EVs.
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Isolation and characterization of extracellular vesicle subpopulations from tissues
Crescitelli, R., Lässer, C., & Lötvall, J. (2021) · Nature Protocols · doi:10.1038/s41596-020-00466-1 · Cited by 507
Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives
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Zhang, X., Deeke, S. A., Ning, Z., Starr, A. E., Butcher, J., Li, J., Mayne, J., Cheng, K., Liao, B., Li, L., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05357-4 · Cited by 258
Mesenchymal Stem Cell-Derived Extracellular Vesicles to the Rescue of Renal Injury
Birtwistle, L., Chen, X.-M., & Pollock, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126596 · Cited by 113
Circulating exosomes in cardiovascular disease: Novel carriers of biological information
Liu, Q., Piao, H., Wang, Y., Zheng, D., & Wang, W. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.111148 · Cited by 70
Metadata
- Authors
- SZATANEK, R., BARAN, J., SIEDLAR, M., & BAJ-KRZYWORZEKA, M.
- Venue
- International Journal of Molecular Medicine
- Publisher
- Spandidos Publications
- Published
- 2015-04-22
- Volume
- 36
- Issue
- 1
- Pages
- 11-17
- ISSN
- 1107-3756 (ISSN-L)
- 1791-244X
- OpenAlex
- W1985619179
- Cited by
- 280
- References
- 54
- FWCI
- 9.65
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- SZATANEK, R., BARAN, J., SIEDLAR, M., & BAJ-KRZYWORZEKA, M. (2015). Isolation of extracellular vesicles: Determining the correct approach (Review). International Journal of Molecular Medicine. https://doi.org/10.3892/ijmm.2015.2194
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