microRNA-9 attenuates amyloidβ-induced synaptotoxicity by targeting calcium/calmodulin-dependent protein kinase kinase 2
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miR-9 inhibits CAMKK2 to protect against Aβ-induced synaptotoxicity and tau phosphorylation.
“and by inhibiting CAMKK2 to protect against Aβ-induced synaptotoxicity and tau phosphorylation (Chang et al., 2014).”
From Cell-specific MicroRNA networks orchestrate the pathogenesis of Alzheimer’s disease (2026) · cites this paper as Chang et al., 2014
miR-9 regulates NSC proliferation, differentiation, and neuronal integration, with context-dependent functional effects in AD-relevant contexts.
“Among these, miR-9 is one of the more extensively studied regulators of NSC proliferation, differentiation, and neuronal integration, and it displays context-dependent functional effects in AD-relevant contexts (Chang et al., 2014; Liu et al., 2020; Roese-Koerner et al., 2017; Xie et al., 2017).”
From Cell-specific MicroRNA networks orchestrate the pathogenesis of Alzheimer’s disease (2026) · cites this paper as Chang et al., 2014
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Cites
Cogswell, J. P., Ward, J., Taylor, I. A., Waters, M., Shi, Y., Cannon, B., Kelnar, K., Kemppainen, J., Brown, D., Chen, C., et al. (2008) · Journal of Alzheimer s Disease · doi:10.3233/jad-2008-14103 · Cited by 943 · see citing works
MicroRNAs in Metabolic Disease
Fernández-Hernando, C., Ramírez, C. M., Goedeke, L., & Suárez, Y. (2013) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.112.300144 · Cited by 257 · cited 2× · see citing works
“Currently, >700 miRNAs have been identified, and are essential in a number of cellular processes, including cell polarity, migration, apoptosis and synaptic plasticity (13).”
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MicroRNAs in Extracellular Vesicles of Alzheimer’s Disease
Li, W., & Zheng, Y. (2023) · Cells · doi:10.3390/cells12101378 · Cited by 43 · see citing works
Cell-specific MicroRNA networks orchestrate the pathogenesis of Alzheimer’s disease
Donepudi, K., Eadha, S., Rodarte, D., Sharma, B., & Kumar, S. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103211
- Authors
- CHANG, F., ZHANG, L.-H., XU, W.-P., JING, P., & ZHAN, P.-Y.
- Venue
- Molecular Medicine Reports
- Publisher
- Spandidos Publications
- Published
- 2014-03-06
- Volume
- 9
- Issue
- 5
- Pages
- 1917-1922
- ISSN
- 1791-2997
- 1791-3004
- Cited by
- 58
- References
- 2
- Language
- en
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