The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
An overview of the antimicrobial resistance mechanisms of bacteria
Open accessAbstract
Resistance to antimicrobial agents has become a major source of morbidity and mortality worldwide. When antibiotics were first introduced in the 1900's, it was thought that we had won the war against microorganisms. It was soon discovered however, that the microorganisms were capable of developing resistance to any of the drugs that were used. Apparently most pathogenic microorganisms have the capability of developing resistance to at least some antimicrobial agents. The main mechanisms of resistance are: limiting uptake of a drug, modification of a drug target, inactivation of a drug, and active efflux of a drug. These mechanisms may be native to the microorganisms, or acquired from other microorganisms. Understanding more about these mechanisms should hopefully lead to better treatment options for infective diseases, and development of antimicrobial drugs that can withstand the microorganisms attempts to become resistant.
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Cites
Updated Functional Classification of β-Lactamases
Bush, K., & Jacoby, G. A. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01009-09 · Cited by 2,367
Clinically Relevant Chromosomally Encoded Multidrug Resistance Efflux Pumps in Bacteria
Piddock, L. J. V. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.19.2.382-402.2006 · Cited by 1,231
Trimethoprim and sulfonamide resistance.
Huovinen, P., Sundström, L., Swedberg, G., & Sköld, O. (1995) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.39.2.279 · Cited by 523
Antibiotic consumption and link to resistance
Goossens, H. (2009) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2009.02725.x · Cited by 379
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Multidrug Resistance (MDR): A Widespread Phenomenon in Pharmacological Therapies
Catalano, A., Iacopetta, D., Ceramella, J., Scumaci, D., Giuzio, F., Saturnino, C., Aquaro, S., Rosano, C., & Sinicropi, M. S. (2022) · Molecules · doi:10.3390/molecules27030616 · Cited by 450
Silva, K. P. T., Sundar, G., & Khare, A. (2023) · Nature Communications · doi:10.1038/s41467-023-38507-4 · Cited by 44
Aspergillus fumigatus Can Display Persistence to the Fungicidal Drug Voriconazole
Scott, J., Valero, C., Mato-López, Á., Donaldson, I. J., Roldán, A., Chown, H., Van Rhijn, N., Lobo-Vega, R., Gago, S., Furukawa, T., et al. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.04770-22 · Cited by 24
Pandey, M., Ojha, D., Bansal, S., Rode, A. B., & Chawla, G. (2021) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2021.101003 · Cited by 23
Mahmud, Z., Shabnam, S. A., Mishu, I. D., Johura, F.-T., Mannan, S. B., Sadique, A., Islam, L. N., & Alam, M. (2021) · Gene Reports · doi:10.1016/j.genrep.2021.101182 · Cited by 9
Dey, R., Valle, D. O., Chakraborty, A., Mayer, K. A., Uppala, J. K., Chakraborty, A., Mirza, S., Skwor, T., Forst, S., & Dey, M. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1560663 · Cited by 1
Metadata
- Authors
- C Reygaert, W., & Department of Biomedical Sciences, O. U. W. B. S. O. M.
- Venue
- AIMS Microbiology
- Published
- 2018
- Volume
- 4
- Issue
- 3
- Pages
- 482-501
- ISSN
- 2471-1888 (ISSN-L)
- OpenAlex
- W2811512821
- Cited by
- 1,893
- References
- 4
- FWCI
- 19.80
- Type
- journal article
- Language
- en
- Open access
- gold
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