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Trends in 24-h urinary sodium excretion in the United States, 1957–2003: a systematic review
Open accessAbstract
Background Few studies have examined temporal trends in sodium intake in the US population. Collections of 24-h urine sodium excretions are reliable markers for dietary sodium intake.Objective We examined temporal trends in 24-h urine sodium excretions to estimate temporal trends in sodium intake in the US population.Design We performed a systematic search of English-language articles in MEDLINE for studies that reported collections of 24-h urine sodium excretions in the United States. We estimated mean urine sodium excretions over time for all studies and demographic subgroups.Results We analyzed 38 studies, which dated from 1957 to 2003, and estimated a mean (± SE) 24-h urine sodium excretion per person of 3526 ± 75 mg Na. In a multivariate random-effects model with study year, sex, age, and race, the study year was not associated with any significant change in sodium excretions (coefficient = 154 mg Na · 24 h⁻¹ · 10 y⁻¹; 95% CI: -140, 448 mg Na · 24 h⁻¹ · 10 y⁻¹). In subgroup analyses, there was no significant temporal trend seen in male, female, black, or white study participants.Conclusion Sodium intake in the US adult population appears to be well above current guidelines and does not appear to have decreased with time.
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“it is rare for anyone to voluntarily follow a diet that low in sodium,19”
From Reducing Dietary Sodium to 1000 mg per Day Reduces Neurovascular Transduction Without Stimulating Sympathetic Outflow (2019) · cites this paper as [19]
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Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & the PRISMA Group* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00135 · Cited by 37,554
Intravenous Fluids and Acute Kidney Injury
Ding, X., Cheng, Z., & Qian, Q. (2017) · Blood Purification · doi:10.1159/000452702 · Cited by 6,868
A Clinical Trial of the Effects of Dietary Patterns on Blood Pressure
Appel, L. J., Moore, T. J., Obarzanek, E., Vollmer, W. M., Svetkey, L. P., Sacks, F. M., Bray, G. A., Vogt, T. M., Cutler, J. A., Windhauser, M. M., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704173361601 · Cited by 5,981
Sacks, F. M., Svetkey, L. P., Vollmer, W. M., Appel, L. J., Bray, G. A., Harsha, D., Obarzanek, E., Conlin, P. R., Miller, E. R., Simons-Morton, D. G., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200101043440101 · Cited by 5,638
Trumbo (2001) · doi:10.1016/s0002-8223(01)00078-5 · Cited by 4,852
Willett, W. C. (1998) · doi:10.1093/acprof:oso/9780195122978.001.0001 · Cited by 4,541
Self-citationNational Center for Health Statistics (NCHS)
Feinleib, M. (2005) · Encyclopedia of Biostatistics · doi:10.1002/0470011815.b2a16042 · Cited by 3,134
Systematic Reviews in Health Care : Meta-Analysis in Context
Egger, M., Smith, G. D., & Altman, D. G. (2000) · Cited by 2,312
Flagged first, then by citations
2 of the 78 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Institute of Medicine Food and Nutrition Board. Water, potassium, sodium, chloride, and sulfate. Dietary reference intakes. Washington, DC: National Academy Press, 2005:270.
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Sorted by citations
Items 101–166 of 166
Dietary Policies and Programs: Moving Beyond Efficacy and Into “Real-World” Settings
Yi, S. S., Lee, M. S. L., Russo, R. G., Li, Y., Trinh‐Shevrin, C., & Kwon, S. C. (2021) · Health Equity · doi:10.1089/heq.2020.0050 · Cited by 15
“Furthermore, evidence suggests modest or no changes in food consumption patterns in recent decades.(4,5) Before investing in adoption and implementation, community-based organizations, public health practitioners, and policymakers—often working with limited resources—need to compare the health impact of different diet…”
BackgroundAmbak, R., He, F. J., Othman, F., Michael, V., Yusoff, M. F. M., & Aris, T. (2021) · Journal of Health Population and Nutrition · doi:10.1186/s41043-021-00229-y · Cited by 14
“These findings are consistent with most studies in other countries such as the USA [27], Spain [28], Sweden [29], and China [26].”
ResultFishman, B., Zloof, Y., Orr, O., Tsur, A. M., Furer, A., Omer, M., Chodick, G., Leiba, A., Derazne, E., Tzur, D., et al. (2021) · Cardiovascular Diabetology · doi:10.1186/s12933-021-01433-0 · Cited by 15
“While dietary changes are associated with hypertension, multinational long-term cross-sectional studies have indicated stable rates of salt consumption across recent decades [38, 39].”
BackgroundPhysiology, Not Policy, Drives Sodium Intake
McCarron, D. A. (2013) · American Journal of Hypertension · doi:10.1093/ajh/hpt151 · Cited by 14
Dietary sodium intake among US adults with hypertension, 1999–2012
Dolmatova, E. V., Moazzami, K., & Bansilal, S. (2017) · Journal of Hypertension · doi:10.1097/hjh.0000000000001558 · Cited by 13
Eufinger, S. C., Votaw, J. R., Faber, T. L., Ziegler, T. R., Goldberg, J. H., Bremner, J. D., & Vaccarino, V. (2012) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.018077 · Cited by 13
“The average sodium intake in the United States, particularly in adults 50 y of age (2), far exceeds the recommended amount (3, 4), possibly as a consequence of readily available processed foods and inexpensive fast food chains (5).”
BackgroundLeshem, M. (2020) · British Journal Of Nutrition · doi:10.1017/s0007114520000173 · Cited by 13
How Robust Is the Evidence for Recommending Very Low Salt Intake in Entire Populations? ∗
Mente, A., O'Donnell, M. J., & Yusuf, S. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.08.008 · Cited by 12
Cooper, J. N., Evans, R. G., Brooks, M. M., Fried, L. F., Holmes, C. E., Barinas‐Mitchell, E., & Sutton-Tyrrell, K. (2013) · Clinical and Experimental Hypertension · doi:10.3109/10641963.2013.789045 · Cited by 12
“The additional goal of the sodium reduction intervention (Low Na) was to gradually reduce daily sodium intake to approximately 1 mg Naþ/ 1 kcal/day, an average reduction of about 50% from the participant’s usual diet (17).”
BackgroundChen, A., Jerums, G., Baqar, S., Lambert, É., Somarajah, G., Thomas, G., O’Callaghan, C., MacIsaac, R. J., & Ekinci, E. I. (2015) · Clinical Science · doi:10.1042/cs20140536 · Cited by 10
Pereira, T. S. S., Mill, J. G., Griep, R. H., Sichieri, R., & Molina, M. D. C. B. (2019) · Medicine · doi:10.1097/md.0000000000016278 · Cited by 10
“Bernstein and Willett([34]) evaluated sodium intake in the American population from 1957 to 2003, concluding that there were no changes in intake and that intake levels remained above recommended levels.”
BackgroundExtreme Sodium Reductions for the Entire Population: Zealotry or Evidence Based?
Mente, A., O'Donnell, M. J., & Yusuf, S. (2013) · American Journal of Hypertension · doi:10.1093/ajh/hpt148 · Cited by 10
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Hummel, S. L., & Konerman, M. C. (2016) · JACC: Heart Failure · doi:10.1016/j.jchf.2015.10.003 · Cited by 14
Quality-oriented diet therapy for chronic kidney disease
Carrero, J. J., St‐Jules, D. E., Biruete, A., Cuppari, L., Piccoli, G. B., Picard, K., Hansen, N. M., Sabatino, A., Winkelman, D., & Avesani, C. M. (2026) · Nature Reviews Nephrology · doi:10.1038/s41581-025-01034-0 · Cited by 10
The Human Penchant for Deranged Salt Balance
Leshem, M. (2013) · Frontiers in neuroscience · doi:10.1201/b15544-2 · Cited by 8
Sodium intake in Germany estimated from sodium excretion measured in spot urine samples
Klenow, S., Thamm, M., & Mensink, G. (2016) · BMC Nutrition · doi:10.1186/s40795-016-0075-5 · Cited by 7
“Women uniformly consume less sodium [40, 43, 44] as a reflection of lower caloric intake with lower intake of nutrients [45].”
BackgroundLipphardt, M., Koziolek, M. J., Lehnig, L.-Y., Schäfer, A.-K. C., Muller, G. A., Lüders, S., & Wallbach, M. (2019) · Clinical Research in Cardiology · doi:10.1007/s00392-019-01464-4 · Cited by 8
Impacto del consumo de alimentos ultraprocesados en la enfermedad renal crónica
Arnal, L. M. L., Vercet, A., Muñoz, A. C., Villarroya, C. M., Calvo, E. L., Navarro, P. M., & París, A. S. (2021) · Nefrología · doi:10.1016/j.nefro.2020.11.013 · Cited by 11
Haddad, N. J., Shim, R., & Hebert, L. A. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-391934-2.00022-9 · Cited by 6
Armanini, D., Bordin, L., Donà, G., Pezzani, R., Ambrosini, G., Andrisani, A., & Sabbadin, C. (2017) · Journal of Clinical Hypertension · doi:10.1111/jch.13019 · Cited by 6
What Level of Sodium Intake Worsens Renal Outcomes?
Lipkowitz, M. S., & Wilcox, C. S. (2014) · American Journal of Hypertension · doi:10.1093/ajh/hpu067 · Cited by 6
Role of Sodium and Sodium Restriction in Heart Failure
Martens, P., & Tang, W. H. W. (2023) · Current Heart Failure Reports · doi:10.1007/s11897-023-00607-z · Cited by 5
Khalid, U., & Deswal, A. M. (2013) · Annals of Internal Medicine · doi:10.7326/0003-4819-158-4-201302190-02007 · Cited by 5
Does the Mediterranean Dietary Pattern Promote Lower Sodium Urinary Excretion in Children?
Rodrigues, M., Mendes, F. C., Padrão, P., Delgado, L., Barros, R., Rufo, J. C., Silva, D., Moreira, A. M., & Moreira, P. A. M. (2023) · Children · doi:10.3390/children10091478 · Cited by 4
“A study reported that mean urinary Na+ concentrations were significantly decreased in participants in the highest tertiles of adherence to the MD [16].”
MethodThe salt debate—More salacious than salubrious
Satin, M. (2011) · Nutrition · doi:10.1016/j.nut.2011.05.003 · Cited by 4
Association between ultrapocessed food and chronic kidney disease
Arnal, L. M. L., Vercet, A., Muñoz, A. C., Villarroya, C. M., Calvo, E. L., Navarro, P. M., & París, A. S. (2021) · Nefrología (English Edition) · doi:10.1016/j.nefroe.2021.11.013 · Cited by 5
Urinary sodium excretion patterns in adult population in spot urine samples
Sequera, G., Cañete, F., Paiva, T., Giménez, E., Santacruz, E., Fretes, G. B. A., & Benítez, G. (2017) · Anales de la Facultad de Ciencias Médicas (Asunción) · doi:10.18004/anales/2017.050(01)51-060 · Cited by 4
Lewis, K. A., Madden, A. M., Tammam, J., Tzilivakis, J., & Vafeiadou, K. (2019) · EFSA Supporting Publications · doi:10.2903/sp.efsa.2019.en-692 · Cited by 3
Farapti, F., Maulia, P. H., Fadilla, C., Yogiswara, N., Rejeki, P. S., Miftahussurur, M., & Majid, H. A. (2022) · F1000Research · doi:10.12688/f1000research.122560.1 · Cited by 4
Wang, N. X., McLean, R. M., Cameron, C., & Skeaff, S. A. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1065710 · Cited by 3
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(EFSA), E. F. S. A. (2017) · EFSA Supporting Publications · doi:10.2903/sp.efsa.2017.en-1356 · Cited by 2
Sanders, T. A. B. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818460-8.00021-6 · Cited by 2
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Hite, A. H. (2011) · Nutrition · doi:10.1016/j.nut.2010.12.003 · Cited by 2
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The dangers of mandating policy in the absence of clear evidence
Satin, M. (2011) · Heart · doi:10.1136/hrt.2010.217778 · Cited by 1
Is a trend to reduced sodium intake in the United States concealed by obesity?
Strazzullo, P., D’Elia, L., & Siani, A. (2011) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.009373 · Cited by 1
A longitudinal comparison of two salt reduction strategies and acceptability of a low sodium food
Bobowski, N. K. (2013) · University of Minnesota Digital Conservancy (University of Minnesota) · Cited by 1
Bernstein, A. M., & Willett, W. C. (2011) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.009597 · Cited by 1
Self-citationSalt intake in a sample of adult population of Novi Sad
Popović, M. B. (2013) · doi:10.2298/ns20130426popovic · Cited by 1
Salt intake and iodine status around the world
Ji, C. (2026) · Warwick Research Archive Portal (University of Warwick) · doi:10.82444/warw.33632551
Does sodium reduction affect mortality?
Korownyk, C. S., Burgess, E. D., & Taylor, I. (2013) · Europe PMC (PubMed Central)
The Salt Debate - Far More Salacious Than Salubrious
Satin, M. (2015) · Blood Purification · doi:10.1159/000368971
Mente, A., Dagenais, G. R., Wielgosz, A. T., Lear, S. A., McQueen, M., Zeidler, J. G., Fu, L., DeJesus, J., Rangarajan, S., Bourlaud, A.-S., et al. (2016)
White Crystals Controversy: Sugar rather than Salt as the Etiology of Hypertension
Nair, T. (2016) · Hypertension Journal · doi:10.5005/jp-journals-10043-0022
Sugar and sodium content of baby foods in South Africa
Marais, N. (2016)
The ‘scent’ and ‘flavour’ of hypertension
Cappuccio, F. P. (2018) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2018.07.001
“However, the human consumption of salt has not declined and has increased in some instances [12], contributing to the development of chronic diseases.”
BackgroundWillett, W. C. (2012) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199754038.003.0016
Self-citationSECTION I Evidence on Lifestyle Factors and Overview
Lin, P.-H., & Svetkey, L. P. (2012) · CRC Press eBooks · doi:10.1201/b12280-5
Sanders, T. A. B. (2012) · Wiley eBooks · doi:10.1002/9781119946045.ch46
Salt, hypertension and cardiovascular outcomes
Drüeke, T. B., & Suter, P. M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821848-8.00099-8
Ingestão e excreção de sódio em idosos institucionalizados no município de Bragança
Rodrigues, C., Martins, T., de Aguiar, V. C., Fernandes, A., & Almeida‐de‐Souza, J. (2016) · Egitania Sciencia · doi:10.46691/es.v2i19.242
Reducing salt intake as a first step to prevent hypertension
Lazić, V., Mulić, M., Todorović, M., Stanić, S., Maksimović, K., & Obrenović, M. (2022) · Hrana i ishrana · doi:10.5937/hraish2202009l
“The amount of ingested sodium necessary to maintain sodium homeostasis in the body is 500 mg per day [18].”
BackgroundSoares, A. P., Rodrigues, M., Padrão, P., Gonçalves, C., Moreira, A. M., & Moreira, P. A. M. (2024) · Nutrients · doi:10.3390/nu16081197
“…excretion (mEq/day), and 24 h sodium excretion using the following formulas, respectively: 23 mg of Na + = 1 mmol of Na + or 1 mEq of Na + [34], and 39.1 mg of K + = 1 mmol of K + On the fi rst morning of collection, they were instructed to discard the initial sample and subsequently…”
MethodInfluentialFarapti, F., Maulia, P. H., Fadilla, C., Yogiswara, N., Rejeki, P. S., Miftahussurur, M., & Majid, H. A. (2024) · F1000Research · doi:10.12688/f1000research.122560.2
Serotonin neurons are necessary for tonic sodium intake inhibition
Gasparini, S., Buchanan, G. F., & Geerling, J. C. (2025) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00029.2025
Sodium Imbalance and Hypertension: An Old and Current Disease
Aguilar-Soto, M., & Solis‐Jiménez, F. (2025) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815305692125010012 · Cited by 1
The impact of a western diet with high salt on metabolic outcomes in male C57bl/6J mice
Ponte, M. E., Prom, J. C., Devkota, P., Yerrathota, S., Carradine, M., Ha, L., Morris, E. M., & Lutkewitte, A. J. (2026) · The Journal of Nutritional Physiology · doi:10.1016/j.jnphys.2026.100025
Fishman, B., Zloof, Y., Orr, O., Tsur, A. M., Furer, A., Omer, M., Chodick, G., Leiba, A., Derazne, E., Tzur, D., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17701646
Rodrigues, M., Pinho, O., Silva-Santos, T., Padrão, P., Moreira, P. A. M., & Gonçalves, C. (2026) · RISE Health Research Journal · doi:10.1097/j.pbj.0000000000000327
Validade de um dia de recolha alimentar às 24 h anteriores para estimativa da ingestão de sódio
Silva, J. F. D. C. E. (2013) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · doi:10.34626/6qv7-hz65
Metadata
- Authors
- Bernstein, A. M., & Willett, W. C.
- Affiliations
- Harvard University (US)
- ORCID
- Willett, Walter C
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2010-11
- Volume
- 92
- Issue
- 5
- Pages
- 1172-1180
- ISSN
- 0002-9165 (ISSN-L)
- PMC
- PMC2954449
- OpenAlex
- W2139499460
- Semantic Scholar
- 806768d9d6a3e9689ebeda05bd3d45dc2dcaf034
- Cited by
- 166
- References
- 78
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 4 · 2023: 5 · 2022: 5 · 2021: 9 · 2020: 3 · 2019: 7 · 2018: 7 · 2017: 12 · 2016: 12 · 2015: 21 · 2014: 18 · 2013: 23 · 2012: 16
- FWCI
- 1.97
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Diabetes and Digestive and Kidney Diseases (DK00703)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Keywords
- sodium intake, 24-hour urinary sodium excretion, temporal trends, dietary sodium, sex differences, racial differences
- MeSH terms
- Diet, Female, Humans, Male, Sodium, Sodium, Dietary, United States, Nutrition Policy
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