Genomic Basis for Methicillin Resistance in Staphylococcus aureus
Open accessAbstract
Since the discovery of the first strain in 1961 in England, MRSA, the most notorious multidrug-resistant hospital pathogen, has spread all over the world. MRSA repeatedly turned down the challenges by number of chemotherapeutics, the fruits of modern organic chemistry. Now, we are in short of effective therapeutic agents against MRSA prevailing among immuno-compromised patients in the hospital. On top of this, we recently became aware of the rise of diverse clones of MRSA, some of which have increased pathogenic potential compared to the classical hospital-associated MRSA, and the others from veterinary sources. They increased rapidly in the community, and started menacing otherwise healthy individuals by causing unexpected acute infection. This review is intended to provide a whole picture of MRSA based on its genetic makeup as a versatile pathogen and our tenacious colonizer.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
To date, 11 different SCCmec allotypes have been described with varying degrees of genetic homology and different sizes, insertion sequences and accompanying resistance genes.
“To date, 11 different SCCmec allotypes have been described with varying degrees of genetic homology and different sizes, insertion sequences and accompanying resistance genes (68, 69).”
From Mechanisms of Antibiotic Resistance (2016) · cites this paper as [68]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility
Hiramatsu, K. (1997) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/40.1.135 · Cited by 1,984 · see citing works
Self-citationWhole genome sequencing of meticillin-resistant Staphylococcus aureus
Kuroda, M., Ohta, T., Uchiyama, I., Baba, T., Yuzawa, H., Kobayashi, I., Cui, L., Oguchi, A., Aoki, K.-I., Nagai, Y., et al. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04403-2 · Cited by 1,950 · see citing works
Self-citation"Celbenin" - resistant Staphylococci
Jevons, M. P. (1961) · BMJ · doi:10.1136/bmj.1.5219.124-a · Cited by 1,683 · see citing works
Diep, B. A., Gill, S. R., Chang, R. F., Phan, T. H., Chen, J. H., Davidson, M. G., Lin, F., Lin, J., Carleton, H. A., Mongodin, E. F., et al. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68231-7 · Cited by 1,633 · see citing works
The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)
Enright, M. C., Robinson, D. A., Randle, G. A., Feil, E. J., Grundmann, H., & Spratt, B. G. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.122108599 · Cited by 1,591 · see citing works
The Changing Epidemiology of Staphylococcus aureus ?
Chambers, H. F. “. (2001) · Emerging infectious diseases · doi:10.3201/eid0702.010204 · Cited by 1,419 · see citing works
Genome and virulence determinants of high virulence community-acquired MRSA
Baba, T., Takeuchi, F., Kuroda, M., Yuzawa, H., Aoki, K.-I., Oguchi, A., Nagai, Y., Iwama, N., Asano, K., Naimi, T. S., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08713-5 · Cited by 1,356 · see citing works
Self-citationChang, S., Sievert, D. M., Hageman, J. C., Boulton, M. L., Tenover, F. C., Downes, F. P., Shah, S., Rudrik, J. T., Pupp, G. R., Brown, W. J., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa025025 · Cited by 1,095 · see citing works
Katayama, Y., Ito, T., & Hiramatsu, K. (2000) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.44.6.1549-1555.2000 · Cited by 1,042 · see citing works
Self-citationGill, S. R., Fouts, D. E., Archer, G. L., Mongodin, E. F., DeBoy, R. T., Ravel, J., Paulsen, I. T., Kolonay, J. F., Brinkac, L. M., Beanan, M., et al. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.7.2426-2438.2005 · Cited by 1,026 · see citing works
Ito, T., Katayama, Y., Asada, K., Mori, N., Tsutsumimoto, K., Tiensasitorn, C., & Hiramatsu, K. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.5.1323-1336.2001 · Cited by 964 · see citing works
Self-citationKondo, Y., Ito, T., Xue, X., Watanabe, S., Kreiswirth, B. N., Étienne, J., & Hiramatsu, K. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00165-06 · Cited by 958 · see citing works
Self-citationGarcía-Álvarez, L., Holden, M. T. G., Lindsay, H., Webb, C. R., Brown, D. F. J., Curran, M. D., Walpole, E., Brooks, K. L., Pickard, D., Teale, C. J., et al. (2011) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70126-8 · Cited by 941 · see citing works
Hartman, B. J., & Tomasz, A. (1984) · Journal of Bacteriology · doi:10.1128/jb.158.2.513-516.1984 · Cited by 893 · see citing works
Stokes, H. W., & Hall, R. M. (1989) · Molecular Microbiology · doi:10.1111/j.1365-2958.1989.tb00153.x · Cited by 889 · see citing works
Dissemination of New Methicillin-Resistant Staphylococcus aureus Clones in the Community
Okuma, K., Iwakawa, K., Turnidge, J. D., Grubb, W. B., Bell, J. M., O’Brien, F. G., Coombs, G. W., Pearman, J. W., Tenover, F. C., Kapi, M., et al. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.11.4289-4294.2002 · Cited by 888 · see citing works
Self-citationHolden, M. T. G., Feil, E. J., Lindsay, J. A., Peacock, S. J., Day, N., Enright, M. C., Foster, T. J., Moore, C. E., Hurst, L. D., Atkin, R. J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402521101 · Cited by 885 · see citing works
The emergence and evolution of methicillin-resistant Staphylococcus aureus
Hiramatsu, K., Cui, L., Kuroda, M., & Ito, T. (2001) · Trends in Microbiology · doi:10.1016/s0966-842x(01)02175-8 · Cited by 825 · see citing works
Self-citation(2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00579-09 · Cited by 804 · see citing works
Ito, T., Xue, X., Takeuchi, F., Okuma, K., Yuzawa, H., & Hiramatsu, K. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.7.2637-2651.2004 · Cited by 677 · see citing works
Self-citationMa, X. X., Ito, T., Tiensasitorn, C., Jamklang, M., Chongtrakool, P., Boyle-Vavra, S., Daum, R. S., & Hiramatsu, K. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.4.1147-1152.2002 · Cited by 587 · see citing works
Self-citationBaba, T., Bae, T., Schneewind, O., Takeuchi, F., & Hiramatsu, K. (2007) · Journal of Bacteriology · doi:10.1128/jb.01000-07 · Cited by 564 · see citing works
Self-citationCellbenin-resistant staphylococci.
Jevons, M. P. (1961) · Medical Entomology and Zoology · Cited by 553 · see citing works
Kuroda, M., Kuroda, H., Oshima, T., Takeuchi, F., Mori, H., & Hiramatsu, K. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03599.x · Cited by 515 · see citing works
Self-citationIto, T., Katayama, Y., & Hiramatsu, K. (1999) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.43.6.1449 · Cited by 451 · see citing works
Self-citationLindsay, J. A., Ruzin, A. V., Ross, H. F., Kurepina, N., & Novick, R. P. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.00947.x · Cited by 414 · see citing works
Zhang, Y., Ren, S., Li, H., Wang, Y., Fu, G., Yang, J., Qin, Z., Miao, Y., Wang, W., Chen, R., et al. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03671.x · Cited by 387 · see citing works
Shore, A. C., Deasy, E. C., Slickers, P., Brennan, G. I., O'Connell, B. C., Monecke, S., Ehricht, R., & Coleman, D. C. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00187-11 · Cited by 383 · see citing works
Chongtrakool, P., Ito, T., Xue, X., Kondo, Y., Trakulsomboon, S., Tiensasitorn, C., Jamklang, M., Chavalit, T., Song, J., & Hiramatsu, K. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.50.3.1001-1012.2006 · Cited by 378 · see citing works
Self-citationUtsui, Y., & Yokota, T. (1985) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.28.3.397 · Cited by 367 · see citing works
Udo, E. E. (1993) · Journal of Hospital Infection · doi:10.1016/0195-6701(93)90100-e · Cited by 358 · see citing works
The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages
Kwan, T., Liu, J., DuBow, M. S., Gros, P., & Pelletier, J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501140102 · Cited by 334 · see citing works
Takeuchi, F., Watanabe, S., Baba, T., Yuzawa, H., Ito, T., Morimoto, Y., Kuroda, M., Cui, L., Takahashi, M., Ankai, A., et al. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.21.7292-7308.2005 · Cited by 331 · see citing works
Self-citationMatsuhashi, M., Song, M., Ishino, F., Wachi, M., Doi, M., Inoue, M., Ubukata, K., Yamashita, N., & Konno, M. (1986) · Journal of Bacteriology · doi:10.1128/jb.167.3.975-980.1986 · Cited by 316 · see citing works
Phage-Mediated Intergeneric Transfer of Toxin Genes
Chen, J. Y.-S., & Novick, R. P. (2009) · Science · doi:10.1126/science.1164783 · Cited by 314 · see citing works
Standard Nomenclature for the Superantigens Expressed byStaphylococcus
Lina, G., Bohach, G. A., Nair, S. P., Hiramatsu, K., Jouvin‐Marche, E., & Mariuzza, R. A. (2004) · The Journal of Infectious Diseases · doi:10.1086/420852 · Cited by 310 · see citing works
Self-citationSong, M. D., Wachi, M., Doi, M., Ishino, F., & Matsuhashi, M. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)80373-3 · Cited by 301 · see citing works
Fitzgerald, J. R., Monday, S. R., Foster, T. J., Bohach, G. A., Hartigan, P. J., Meaney, W. J., & Smyth, C. J. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.1.63-70.2001 · Cited by 280 · see citing works
Highlander, S. K., Hultén, K. G., Qin, X., Jiang, H., Yerrapragada, S., Mason, E. O., Shang, Y., Williams, T. M., Fortunov, R. M., Liu, Y., et al. (2007) · BMC Microbiology · doi:10.1186/1471-2180-7-99 · Cited by 260 · see citing works
A Proteolytic Transmembrane Signaling Pathway and Resistance to β-Lactams in Staphylococci
Zhang, H. Z., Hackbarth, C. J., Chansky, K., & Chambers, H. F. “. (2001) · Science · doi:10.1126/science.1055144 · Cited by 253 · see citing works
Molecular Correlates of Host Specialization in Staphylococcus aureus
Herron‐Olson, L., Fitzgerald, J. R., Musser, J. M., & Kapur, V. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001120 · Cited by 245 · see citing works
Methicillin-Resistant Staphylococcus aureus as a Community Organism
Moreno, F., Crisp, C., Jorgensen, J. H., & PATTERSON, J. E. (1995) · Clinical Infectious Diseases · doi:10.1093/clinids/21.5.1308 · Cited by 239 · see citing works
Langley, R. J., Wines, B. D., Willoughby, N., Basu, I., Proft, T., & Fraser, J. D. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.5.2926 · Cited by 237 · see citing works
Ubukata, K., Yamashita, N., & Konno, M. (1985) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.27.5.851 · Cited by 234 · see citing works
Yamaguchi, T., Nishifuji, K., Sasaki, M., Fudaba, Y., Aepfelbacher, M., Takata, T., Ohara, M., Komatsuzawa, H., Amagai, M., & Sugai, M. (2002) · Infection and Immunity · doi:10.1128/iai.70.10.5835-5845.2002 · Cited by 230 · see citing works
Vancomycin resistance in staphylococci
Hiramatsu, K. (1998) · Drug Resistance Updates · doi:10.1016/s1368-7646(98)80029-0 · Cited by 226 · see citing works
Self-citationOrigin and Molecular Evolution of the Determinant of Methicillin Resistance in Staphylococci
Tsubakishita, S., Kuwahara‐Arai, K., Sasaki, T., & Hiramatsu, K. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00356-10 · Cited by 212 · see citing works
Self-citationHiramatsu, K. (1995) · Microbiology and Immunology · doi:10.1111/j.1348-0421.1995.tb02239.x · Cited by 206 · see citing works
Self-citationKuroda, M., Kuwahara‐Arai, K., & Hiramatsu, K. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.2277 · Cited by 190 · see citing works
Self-citationIntrinsic resistance to β‐lactam antibiotics in staphylococcus aureus
Brown, D. F. J., & Reynolds, P. E. (1980) · FEBS Letters · doi:10.1016/0014-5793(80)80455-8 · Cited by 188 · see citing works
Kozitskaya, S., Cho, S.-H., Dietrich, K., Marre, R., Naber, K. G., & Ziebuhr, W. (2004) · Infection and Immunity · doi:10.1128/iai.72.2.1210-1215.2004 · Cited by 187 · see citing works
Wu, S., C, P., de LENCASTRE, H., & Tomasz, A. (1996) · Microbial Drug Resistance · doi:10.1089/mdr.1996.2.435 · Cited by 185 · see citing works
Hiramatsu, K., Asada, K., Suzuki, E., Okonogi, K., & Yokota, T. (1992) · FEBS Letters · doi:10.1016/0014-5793(92)80039-j · Cited by 182 · see citing works
Self-citationSchnellmann, C., Gerber, V., Rossano, A., Jaquier, V., Panchaud, Y., Doherr, M. G., Thomann, A., Straub, R., & Perreten, V. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.00868-06 · Cited by 178 · see citing works
Molecular genetics of methicillin-resistant Staphylococcus aureus
Hiramatsu, K., Katayama, Y., Yuzawa, H., & Ito, T. (2002) · International Journal of Medical Microbiology · doi:10.1078/1438-4221-00192 · Cited by 168 · see citing works
Self-citationWilliamson, R., Bouguénec, C. L., Gutmann, L., & Horaud, T. (1985) · Microbiology · doi:10.1099/00221287-131-8-1933 · Cited by 157 · see citing works
Ryffel, C., Kayser, F. H., & Berger‐Bächi, B. (1992) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.36.1.25 · Cited by 151 · see citing works
Dissemination of Methicillin-Resistant Staphylococci among Healthy Japanese Children
Hisata, K., Kuwahara‐Arai, K., Yamanoto, M., Ito, T., Nakatomi, Y., Cui, L., Baba, T., Terasawa, M., Sotozono, C., Kinoshita, S., et al. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.7.3364-3372.2005 · Cited by 147 · see citing works
Self-citationCharacterization and Expression Analysis of Staphylococcus aureus Pathogenicity Island 3
Yarwood, J. M., McCormick, J. K., Paustian, M. L., Orwin, P. M., Kapur, V., & Schlievert, P. M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111661200 · Cited by 146 · see citing works
Distribution of mec regulator genes in methicillin-resistant Staphylococcus clinical strains
Suzuki, E., Kuwahara‐Arai, K., Richardson, J. F., & Hiramatsu, K. (1993) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.37.6.1219 · Cited by 144 · see citing works
Self-citationMechanisms of heteroresistance in methicillin-resistant Staphylococcus aureus
Ryffel, C., Strässle, A., Kayser, F. H., & Berger‐Bächi, B. (1994) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.38.4.724 · Cited by 140 · see citing works
Colony Spreading in Staphylococcus aureus
Kaito, C., & Sekimizu, K. (2006) · Journal of Bacteriology · doi:10.1128/jb.01635-06 · Cited by 139 · see citing works
Kuwahara‐Arai, K., Kondo, N., Hori, S., Tateda-Suzuki, E., & Hiramatsu, K. (1996) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.40.12.2680 · Cited by 136 · see citing works
Self-citationA Role in vivo for Penicillin‐Binding Protein‐4 of Staphylococcus aureus
Wyke, A. W., Ward, J. B., HAYES, M. V., & Curtis, N. A. C. (1981) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1981.tb05620.x · Cited by 136 · see citing works
Clarke, S. R., Harris, L. G., Richards, R. G., & Foster, S. J. (2002) · Infection and Immunity · doi:10.1128/iai.70.12.6680-6687.2002 · Cited by 133 · see citing works
Genome Analysis of the Meat Starter Culture BacteriumStaphylococcus carnosusTM300
Rosenstein, R., Nerz, C., Biswas, L., Resch, A., Raddatz, G., Schuster, S. C., & Götz, F. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.01982-08 · Cited by 130 · see citing works
Kaito, C., Saito, Y., Nagano, G., Ikuo, M., Omae, Y., Hanada, Y., Han, X., Kuwahara‐Arai, K., Hishinuma, T., Baba, T., et al. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1001267 · Cited by 130 · see citing works
Self-citationÚbeda, C., Tormo‐Más, M. Á., Cucarella, C., Trotonda, M. P., Foster, T. J., Lasa, Í., & Penadés, J. R. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03577.x · Cited by 126 · see citing works
Baba, T., Kuwahara‐Arai, K., Uchiyama, I., Takeuchi, F., Ito, T., & Hiramatsu, K. (2008) · Journal of Bacteriology · doi:10.1128/jb.01058-08 · Cited by 126 · see citing works
Self-citationMongkolrattanothai, K., Boyle, S., Murphy, T. V., & Daum, R. S. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.5.1823-1836.2004 · Cited by 123 · see citing works
Ruppé, É., Barbier, F., Mesli, Y., Maïga, A., Cojocaru, R., Benkhalfat, M., Benchouk, S., Hassaïne, H., Maïga, I., Diallo, A., et al. (2008) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00724-08 · Cited by 122 · see citing works
The SaPIs: Mobile Pathogenicity Islands of Staphylococcus
Novick, R. P., & Subedi, A. (2007) · KARGER eBooks · doi:10.1159/000100857 · Cited by 121 · see citing works
Kaito, C., Saito, Y., Ikuo, M., Omae, Y., Mao, H., Nagano, G., Fujiyuki, T., Numata, S., Han, X., Obata, K., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003269 · Cited by 120 · see citing works
Self-citationLee, S. M., Ender, M., Adhikari, R. P., Smith, J. M. B., Berger‐Bächi, B., & Cook, G. M. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01239-06 · Cited by 119 · see citing works
Gustafson, J. E., Strässle, A., Hächler, H., Kayser, F. H., & Berger‐Bächi, B. (1994) · Journal of Bacteriology · doi:10.1128/jb.176.5.1460-1467.1994 · Cited by 111 · see citing works
Chromosomal map location of the methicillin resistance determinant in Staphylococcus aureus
Kuhl, S. A., Pattee, P. A., & Baldwin, J. N. (1978) · Journal of Bacteriology · doi:10.1128/jb.135.2.460-465.1978 · Cited by 104 · see citing works
sarU , a sarA Homolog, Is Repressed by SarT and Regulates Virulence Genes in Staphylococcus aureus
Manna, A. C., & Cheung, A. L. (2002) · Infection and Immunity · doi:10.1128/iai.71.1.343-353.2003 · Cited by 103 · see citing works
Matsuo, M., Hishinuma, T., Katayama, Y., Cui, L., Kapi, M., & Hiramatsu, K. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00398-11 · Cited by 100 · see citing works
Self-citationLuong, T. T., Ouyang, S., Bush, K., & Lee, C. Y. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.13.3623-3629.2002 · Cited by 99 · see citing works
Staphylococcus aureus Pathogenicity Island DNA Is Packaged in Particles Composed of Phage Proteins
Tormo‐Más, M. Á., Ferrer, M. D., Maiques, E., Úbeda, C., Selva, L., Lasa, Í., Calvete, J. J., Novick, R. P., & Penadés, J. R. (2008) · Journal of Bacteriology · doi:10.1128/jb.01349-07 · Cited by 98 · see citing works
Staphylococcal Cassette Chromosome mec -Like Element in Macrococcus caseolyticus
Tsubakishita, S., Kuwahara‐Arai, K., Baba, T., & Hiramatsu, K. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00575-09 · Cited by 97 · see citing works
Self-citationChatterjee, S. S., Chen, L., Joo, H., Cheung, G. Y. C., Kreiswirth, B. N., & Otto, M. J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028781 · Cited by 96 · see citing works
O’Neill, A. J., Larsen, A. R., Skov, R. L., Henriksen, A. S., & Chopra, I. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.01984-06 · Cited by 96 · see citing works
Jamaluddin, T. Z. M. T., Kuwahara‐Arai, K., Hisata, K., Terasawa, M., Cui, L., Baba, T., Sotozono, C., Kinoshita, S., Ito, T., & Hiramatsu, K. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.02262-07 · Cited by 86 · see citing works
Self-citationTesch, W., Ryffel, C., Strässle, A., Kayser, F. H., & Berger‐Bächi, B. (1990) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.34.9.1703 · Cited by 83 · see citing works
SaPI operon I is required for SaPI packaging and is controlled by LexA
Úbeda, C., Maiques, E., Tormo‐Más, M. Á., Campoy, S., Lasa, Í., Barbé, J., Novick, R. P., & Penadés, J. R. (2007) · Molecular Microbiology · doi:10.1111/j.1365-2958.2007.05758.x · Cited by 83 · see citing works
Aubry-Damon, H., Legrand, P., Brun‐Buisson, C., Astier, A., Soussy, C., & Leclercq, R. (1997) · Clinical Infectious Diseases · doi:10.1086/513749 · Cited by 80 · see citing works
Hongo, I., Baba, T., Oishi, K., Morimoto, Y., Ito, T., & Hiramatsu, K. (2009) · The Journal of Infectious Diseases · doi:10.1086/605332 · Cited by 80 · see citing works
Self-citationHürlimann-Dalel, R. L., Ryffel, C., Kayser, F. H., & Berger‐Bächi, B. (1992) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.36.12.2617 · Cited by 79 · see citing works
A Staphylococcus xylosus Isolate with a New mecC Allotype
Harrison, E. M., Paterson, G. K., Holden, M. T. G., Morgan, F. J. E., Larsen, A. R., Petersen, A., Léroy, S., Vliegher, S. D., Perreten, V., Fox, L. K., et al. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01882-12 · Cited by 78 · see citing works
Uchiyama, I. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl978 · Cited by 76 · see citing works
Uchiyama, I. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkj448 · Cited by 75 · see citing works
Sjöström, J.-E., Löfdahl, S., & Philipson, L. (1975) · Journal of Bacteriology · doi:10.1128/jb.123.3.905-915.1975 · Cited by 72 · see citing works
Intrinsic Penicillin Resistance in Enterococci
Fontana, R., Ligozzi, M., Pittaluga, F., & Satta, G. (1996) · Microbial Drug Resistance · doi:10.1089/mdr.1996.2.209 · Cited by 71 · see citing works
Hiramatsu, K., Suzuki, E., Takayama, H., Katayama, Y., & Yokota, T. (1990) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.34.4.600 · Cited by 70 · see citing works
Self-citationKondo, N., Kuwahara‐Arai, K., Murakami-Kuroda, H., Tateda-Suzuki, E., & Hiramatsu, K. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.3.815-824.2001 · Cited by 68 · see citing works
Self-citationKharroubi, A. E., Jacques, P., Piras, G., BEEUMEN, J. V., Coyette, J., & Ghuysen, J. (1991) · Biochemical Journal · doi:10.1042/bj2800463 · Cited by 67 · see citing works
Changing epidemiology of methicillin‐resistant Staphylococcus aureus in Western Australia
Riley, T. V., Pearman, J. W., & Rouse, I. L. (1995) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1995.tb124656.x · Cited by 67 · see citing works
Hiramatsu, K., Igarashi, M., Morimoto, Y., Baba, T., Umekita, M., & Akamatsu, Y. (2012) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2012.02.007 · Cited by 62 · see citing works
Self-citationMaki, H., & Murakami, K. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.22.6944-6948.1997 · Cited by 62 · see citing works
Genetic basis for molecular epidemiology of MRSA
Hiramatsu, K., Kondo, N., & Ito, T. (1996) · Journal of Infection and Chemotherapy · doi:10.1007/bf02351563 · Cited by 60 · see citing works
Self-citationGenetic behavior of the methicillin resistance determinant in Staphylococcus aureus
Stewart, G. C., & Rosenblum, E. D. (1980) · Journal of Bacteriology · doi:10.1128/jb.144.3.1200-1202.1980 · Cited by 52 · see citing works
Subedi, A., Úbeda, C., Adhikari, R. P., Penadés, J. R., & Novick, R. P. (2007) · Microbiology · doi:10.1099/mic.0.2007/006932-0 · Cited by 52 · see citing works
Wada, A., Katayama, Y., Hiramatsu, K., & Yokota, T. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)90430-f · Cited by 50 · see citing works
Self-citationAiba, Y., Katayama, Y., Hishinuma, T., Murakami-Kuroda, H., Cui, L., & Hiramatsu, K. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00720-13 · Cited by 48 · see citing works
Self-citationKaito, C., Omae, Y., Matsumoto, Y., Nagata, M., Yamaguchi, H., Aoto, T., Ito, T., Hiramatsu, K., & Sekimizu, K. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003921 · Cited by 47 · see citing works
Self-citationPiras, G., Raze, D., Kharroubi, A. E., Hastir, D., Englebert, S., Coyette, J., & Ghuysen, J. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.10.2844-2852.1993 · Cited by 46 · see citing works
Yamakawa, J., Kurosawa, H., Kaneko, K., Yamakawa, J., AMINAKA, M., Hori, S., Cui, L., Ito, T., Jin, J., Hiramatsu, K., et al. (2011) · Journal of Infection and Chemotherapy · doi:10.1007/s10156-011-0330-2 · Cited by 35 · see citing works
Self-citationUchiyama, I. (2008) · BMC Genomics · doi:10.1186/1471-2164-9-515 · Cited by 31 · see citing works
Genetic Basis for Molecular Epidemiology of MRSA.
Kondo, N., Ito, T., & Hiramatsu, K. (1997) · Nippon Saikingaku Zasshi · doi:10.3412/jsb.52.417 · Cited by 29 · see citing works
Self-citationWatanabe, S., Ito, T., Morimoto, Y., Takeuchi, F., & Hiramatsu, K. (2007) · Journal of Bacteriology · doi:10.1128/jb.01485-06 · Cited by 22 · see citing works
Self-citationEffects of Penicillin-Binding Protein 4 Overproduction in Staphylococcus aureus
Henze, U., Roos, M. A., & Berger‐Bächi, B. (1996) · Microbial Drug Resistance · doi:10.1089/mdr.1996.2.193 · Cited by 21 · see citing works
The Staphylococcus aureus Genome
Baba, T., Takeuchi, F., Kuroda, M., Ito, T., Yuzawa, H., & Hiramatsu, K. (2004) · Elsevier eBooks · doi:10.1016/b978-1-898563-96-9.50008-7 · Cited by 12 · see citing works
Self-citation
Flagged first, then by citations
1 of the 114 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Mechanisms of Antibiotic Resistance
Munita, J. M., & Arias, C. A. (2016) · Microbiology Spectrum · doi:10.1128/microbiolspec.vmbf-0016-2015 · Cited by 2,782 · see citing works
What is a resistance gene? Ranking risk in resistomes
Martínez, J., Coque, T., & Baquero, F. (2014) · Nature Reviews Microbiology · doi:10.1038/nrmicro3399 · Cited by 938 · see citing works
Antimicrobial Resistance in Bacteria: Mechanisms, Evolution, and Persistence
Christaki, E., Marcou, M., & Tofarides, A. G. (2019) · Journal of Molecular Evolution · doi:10.1007/s00239-019-09914-3 · Cited by 818 · see citing works
Antibiotic Resistance and the MRSA Problem
Vestergaard, M. R., Frees, D., & Ingmer, H. (2019) · Microbiology Spectrum · doi:10.1128/microbiolspec.gpp3-0057-2018 · Cited by 515 · see citing works
Mechanisms of antibiotic resistance
Munita, J. M., & Arias, C. A. (2016) · Virulence Mechanisms of Bacterial Pathogens · doi:10.1128/9781555819286.ch17 · Cited by 421 · see citing works
Kaya, H., Hasman, H., Larsen, J., Stegger, M., Johannesen, T. B., Allesøe, R. L., Lemvigh, C. K., Aarestrup, F. M., Lund, O., & Larsen, A. R. (2018) · mSphere · doi:10.1128/msphere.00612-17 · Cited by 302 · see citing works
Bacteria from Animals as a Pool of Antimicrobial Resistance Genes
Argudín, M. Á., Deplano, A., Meghraoui, A., Dodémont, M., Heinrichs, A., Denis, O., Nonhoff, C., & Roisin, S. (2017) · Antibiotics · doi:10.3390/antibiotics6020012 · Cited by 286 · see citing works
Belay, W. Y., Getachew, M., Tegegne, B. A., Teffera, Z. H., Dagne, A., Zeleke, T. K., Abebe, R. B., Gedif, A. A., Fenta, A., Yirdaw, G., et al. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1444781 · Cited by 278 · see citing works
Multi-drug-resistant Staphylococcus aureus and future chemotherapy
Hiramatsu, K., Katayama, Y., Matsuo, M., Sasaki, T., Morimoto, Y., Sekiguchi, A., & Baba, T. (2014) · Journal of Infection and Chemotherapy · doi:10.1016/j.jiac.2014.08.001 · Cited by 246 · see citing works
Self-citationAntibiotic Resistance in the Treatment of Staphylococcus aureus Keratitis
Chang, V. S., Dhaliwal, D. K., Raju, L. V., & Kowalski, R. P. (2015) · Cornea · doi:10.1097/ico.0000000000000431 · Cited by 175 · see citing works
Miragaia, M. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02723 · Cited by 170 · see citing works
Streptomyces as a Prominent Resource of Future Anti-MRSA Drugs
Kemung, H. M., Tan, L. T., Khan, T. M., Chan, K., Pusparajah, P., Goh, B. H., & Lee, L. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02221 · Cited by 142 · see citing works
Bal, A. M., Coombs, G. W., Holden, M. T. G., Lindsay, J. A., Nimmo, G. R., Tattevin, P., & Skov, R. L. (2016) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2016.04.004 · Cited by 136 · see citing works
Novel SCC mec type XIII (9A) identified in an ST152 methicillin-resistant Staphylococcus aureus
Baig, S., Johannesen, T. B., Overballe‐Petersen, S., Larsen, J., Larsen, A. R., & Stegger, M. (2018) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2018.03.013 · Cited by 120 · see citing works
The Plasmidome of Firmicutes: Impact on the Emergence and the Spread of Resistance to Antimicrobials
Lanza, V. F., Tedim, A. P., Martínez, J. L., Baquero, F., & Coque, T. M. (2015) · Microbiology Spectrum · doi:10.1128/microbiolspec.plas-0039-2014 · Cited by 115 · see citing works
Schwendener, S., Cotting, K., & Perreten, V. (2017) · Scientific Reports · doi:10.1038/srep43797 · Cited by 103 · see citing works
Vancomycin-intermediate resistance in Staphylococcus aureus
Hiramatsu, K., Kayayama, Y., Matsuo, M., Aiba, Y., Saito, M., Hishinuma, T., & Iwamoto, A. (2014) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2014.04.006 · Cited by 101 · see citing works
Self-citationApreja, M., Sharma, A., Balda, S., Kataria, K., Capalash, N., & Sharma, P. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-17374-w · Cited by 97 · see citing works
Staphylococcus aureus in Agriculture: Lessons in Evolution from a Multispecies Pathogen
Park, S.-Y., & Ronholm, J. (2021) · Clinical Microbiology Reviews · doi:10.1128/cmr.00182-20 · Cited by 105 · see citing works
O’Brien, F. G., Eto, K. Y., Murphy, R. J. T., Fairhurst, H. M., Coombs, G. W., Grubb, W. B., & Ramsay, J. P. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv755 · Cited by 86 · see citing works
Novel integrative elements and genomic plasticity in ocean ecosystems
Hackl, T., Laurenceau, R., Ankenbrand, M. J., Bliem, C., Cariani, Z., Thomas, E., Dooley, K. D., Arellano, A. A., Hogle, S., Berube, P. M., et al. (2023) · Cell · doi:10.1016/j.cell.2022.12.006 · Cited by 87 · see citing works
Panchal, V. V., Griffiths, C., Mosaei, H., Bilyk, B. L., Sutton, J. A. F., Carnell, O. T., HORNBY, D. P., Green, J. D., Hobbs, J. K., Kelley, W. L., et al. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008672 · Cited by 85 · see citing works
Evidence for the evolutionary steps leading to mecA-mediated β-lactam resistance in staphylococci
Rolo, J., Worning, P., Nielsen, J. B., Sobral, R. G., Bowden, R. J., Bouchami, O., Damborg, P., Guardabassi, L., Perreten, V., Westh, H., et al. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006674 · Cited by 90 · see citing works
Urushibara, N., Aung, M. S., Kawaguchiya, M., & Kobayashi, N. (2019) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkz406 · Cited by 73 · see citing works
The History of Infectious Diseases and Medicine
Sakai, T., & Morimoto, Y. (2022) · Pathogens · doi:10.3390/pathogens11101147 · Cited by 69 · see citing works
Self-citationRecent Approaches for Downplaying Antibiotic Resistance: Molecular Mechanisms
Ahmed, S., Ahmed, M. Z., Rafique, S., Almasoudi, S. E., Shah, M., Jalil, N. A. C., & Ojha, S. C. (2023) · BioMed Research International · doi:10.1155/2023/5250040 · Cited by 75 · see citing works
Clinical and Molecular Epidemiology of Staphylococcal Toxic Shock Syndrome in the United Kingdom
Sharma, H., Smith, D. S., Turner, C. E., Gamé, L., Pichon, B., Hope, R., Hill, R., Kearns, A., & Sriskandan, S. (2018) · Emerging infectious diseases · doi:10.3201/eid2402.170606 · Cited by 68 · see citing works
Overcoming Multidrug Resistance of Antibiotics via Nanodelivery Systems
Imran, M., Jha, S. K., Hasan, N., Insaf, A., Shrestha, J., Shrestha, J., Devkota, H. P., Khan, S., Panth, N., Warkiani, M. E., et al. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14030586 · Cited by 69 · see citing works
Brown-Jaque, M., Calero‐Cáceres, W., Espinal, P., Rodríguez-Navarro, J., Miró, E., González‐López, J. J., Cornejo, T., Hurtado, J. C., Navarro, F., & Muniesa, M. (2017) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2017.11.014 · Cited by 63 · see citing works
Point-of-care testing system for digital single cell detection of MRSA directly from nasal swabs
Schulz, M., Calabrese, S., Hausladen, F., Wurm, H., Drossart, D., Stock, K., Sobieraj, A. M., Eichenseher, F., Loessner, M. J., Schmelcher, M., et al. (2020) · Lab on a Chip · doi:10.1039/d0lc00294a · Cited by 59 · see citing works
Strauß, L., Ruffing, U., Abdulla, S., Alabi, A. S., Akulenko, R., Garrine, M., Germann, A., Grobusch, M. P., Helms, V., Herrmann, M., et al. (2016) · Journal of Clinical Microbiology · doi:10.1128/jcm.03022-15 · Cited by 52 · see citing works
Antibiotic Resistance and the MRSA Problem
Vestergaard, M. R., Frees, D., & Ingmer, H. (2019) · ASM Press eBooks · doi:10.1128/9781683670131.ch47 · Cited by 52 · see citing works
Schwendener, S., & Perreten, V. (2022) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkac107 · Cited by 53 · see citing works
Wang, X., Liu, Q., Zhang, H., Li, X., Huang, W., Fu, Q., & Li, M. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01211 · Cited by 49 · see citing works
Guay, I., Boulanger, S., Isabelle, C., Brouillette, É., Chagnon, F., Bouarab, K., Marsault, É., & Malouin, F. (2018) · BMC Pharmacology and Toxicology · doi:10.1186/s40360-018-0197-2 · Cited by 48 · see citing works
Novais, C., Tedim, A. P., Lanza, V. F., Freitas, A. R., Silveira, E., Escada, R., Roberts, A. P., Al‐Haroni, M., Baquero, F., Peixe, L. M. S. V., et al. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01581 · Cited by 48 · see citing works
Alfouzan, W. A., Udo, E. E., Modhaffer, A., & Alosaimi, A. (2019) · Scientific Reports · doi:10.1038/s41598-019-54794-8 · Cited by 47 · see citing works
Mazhar, S., Hill, C., & McAuliffe, O. E. (2018) · Advances in applied microbiology · doi:10.1016/bs.aambs.2018.05.002 · Cited by 41 · see citing works
Staphylococci: Evolving Genomes
Lindsay, J. A. (2019) · Microbiology Spectrum · doi:10.1128/microbiolspec.gpp3-0071-2019 · Cited by 39 · see citing works
Nijhuis, R. H. T., van Maarseveen, N. M., van Hannen, E. J., van Zwet, A. A., & Mascini, E. M. (2014) · Journal of Clinical Microbiology · doi:10.1128/jcm.00808-14 · Cited by 39 · see citing works
Singh, R., & Kim, K. (2024) · Emerging contaminants · doi:10.1016/j.emcon.2024.100440 · Cited by 41 · see citing works
Nepal, R., Houtak, G., Shaghayegh, G., Bouras, G. S., Shearwin, K. E., Psaltis, A. J., Wormald, P., & Vreugde, S. (2021) · Microbial Genomics · doi:10.1099/mgen.0.000726 · Cited by 35 · see citing works
Silva‐Santana, G. (2025) · Research in Microbiology · doi:10.1016/j.resmic.2025.104267 · Cited by 35 · see citing works
Muzammil, I., Ijaz, M. U., Saleem, M. H., & Ali, M. M. (2022) · Microbial Pathogenesis · doi:10.1016/j.micpath.2022.105691 · Cited by 32 · see citing works
Dhungel, S., Rijal, K. R., Yadav, B., Dhungel, B., Adhikari, N., Shrestha, U. T., Adhikari, B., Banjara, M. R., & Ghimire, P. (2021) · Infectious Diseases Research and Treatment · doi:10.1177/11786337211037355 · Cited by 34 · see citing works
Zuo, H., Uehara, Y., Lu, Y., Sasaki, T., & Hiramatsu, K. (2021) · Scientific Reports · doi:10.1038/s41598-021-84481-6 · Cited by 28 · see citing works
Self-citationSheikh, A. F., Dezfuli, A. A. Z., Navidifar, T., Fard, S. S., & Dehdashtian, M. (2019) · Infection and Drug Resistance · doi:10.2147/idr.s204432 · Cited by 28 · see citing works
Jani, M., Sengupta, S., Hu, K. Y., & Azad, R. K. (2017) · Open Biology · doi:10.1098/rsob.170094 · Cited by 27 · see citing works
Boswihi, S. S., Udo, E. E., Mathew, B., Noronha, B., Verghese, T., & Tappa, S. B. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02912 · Cited by 27 · see citing works
Zhao, R., Wang, X., Wang, X., Du, B., Xu, K., Zhang, F., Jiang, C., Zhao, Y., & Zhu, Y. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1008052 · Cited by 26 · see citing works
Rosado, P. C., Marques, M. M., & Justino, G. C. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.117048 · Cited by 25 · see citing works
Lu, Y., Sasaki, T., Kuwahara‐Arai, K., Uehara, Y., & Hiramatsu, K. (2018) · Applied and Environmental Microbiology · doi:10.1128/aem.00517-18 · Cited by 24 · see citing works
Self-citationNovel integrative elements and genomic plasticity in ocean ecosystemsPreprint
Hackl, T., Laurenceau, R., Ankenbrand, M. J., Bliem, C., Cariani, Z., Thomas, E., Dooley, K. D., Arellano, A. A., Hogle, S., Berube, P. M., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.28.424599 · Cited by 23 · see citing works
Spiliopoulou, I. T., & Petinaki, E. (2015) · Veterinary Medicine Research and Reports · doi:10.2147/vmrr.s91313 · Cited by 22 · see citing works
Prediction of allosteric sites and signaling: Insights from benchmarking datasets
Wu, N., Strömich, L., & Yaliraki, S. N. (2021) · Patterns · doi:10.1016/j.patter.2021.100408 · Cited by 23 · see citing works
Ogura, K., Kaji, D., Sasaki, M., Otsuka, Y., Takemoto, N., Miyoshi‐Akiyama, T., & Kikuchi, K. (2022) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2022.01.011 · Cited by 22 · see citing works
Wan, T., Hung, W., Tsai, J., Lin, Y.-T., Lee, H., Hsueh, P., Lee, T.-F., & Teng, L. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01096-16 · Cited by 21 · see citing works
Batistão, D. W. D. F., de Campos, P. A., Camilo, N. C., Royer, S., Fuga, B., Naves, K. S. C., Martins, M. I. B. C., Pereira, M. O., Henriques, M., Gontijo-Filho, P. P., et al. (2016) · Journal of Medical Microbiology · doi:10.1099/jmm.0.000228 · Cited by 22 · see citing works
Uehara, Y., Sasaki, T., Baba, T., Lu, Y., Imajo, E., Sato, Y., Tanno, S., Furuichi, M., Kawada, M., & Hiramatsu, K. (2019) · BMC Infectious Diseases · doi:10.1186/s12879-018-3646-z · Cited by 20 · see citing works
Self-citationAdvancement towards Antibiotic Remediation: Heterostructure and Composite materials
Bhattacharyya, P., Basak, S., & Chakrabarti, S. (2021) · ChemistrySelect · doi:10.1002/slct.202100436 · Cited by 20 · see citing works
Okado, J. B., Avaca-Crusca, J. S., Oliveira, A. L., Dabul, A. N. G., & Camargo, I. L. B. D. C. (2018) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2018.05.001 · Cited by 20 · see citing works
Watanabe, S., Nsofor, C. A., Thitiananpakorn, K., Tan, X.-E., Aiba, Y., Takenouchi, R., Kiga, K., Sasahara, T., Miyanaga, K., Veeranarayanan, S., et al. (2024) · mBio · doi:10.1128/mbio.00339-24 · Cited by 19 · see citing works
Narayan, K. S., Adhikari, N., Dhungel, B., Shrestha, U. T., Angbuhang, K. B., Karki, G., Adhikari, B., Banjara, M. R., Rijal, K. R., & Ghimire, P. (2020) · Microbiology Insights · doi:10.1177/1178636120972695 · Cited by 20 · see citing works
da Cunha, I. V., Oliveira, D. D. D. S., Calefi, G. G., Silva, N. B. S., Martins, C. H. G., Júnior, C. D. O. R., & Tsubone, T. M. (2024) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2024.117197 · Cited by 17 · see citing works
El‐Deeb, W., Cave, R. J., Fayez, M., Alhumam, N., Quadri, S. A. Q., & Mkrtchyan, H. V. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.00387-22 · Cited by 17 · see citing works
Hirvonen, J. J. (2014) · Biomarkers in Medicine · doi:10.2217/bmm.14.60 · Cited by 17 · see citing works
Saklani, P., Lekshmi, M., Nayak, B. B., & Kumar, S. H. (2020) · Journal of Food Protection · doi:10.4315/jfp-19-546 · Cited by 17 · see citing works
Tsujiwaki, A., Hisata, K., Tohyama, Y., Matsunaga, N., Uehara, Y., Sasaki, T., Hiramatsu, K., & Shimizu, T. (2020) · Pediatrics International · doi:10.1111/ped.14241 · Cited by 17 · see citing works
Self-citationde Oliveira, C. F., Morey, A. T., Santos, J. P., Gomes, L. V. P., Cardoso, J., Pinge‐Filho, P., Perugini, M. R. E., Yamauchi, L. M., & Yamada‐Ogatta, S. F. (2015) · The Journal of Infection in Developing Countries · doi:10.3855/jidc.5868 · Cited by 17 · see citing works
Mortazavi, S. S., Haghighat, S., & Mahdavi, M. (2019) · Microbial Pathogenesis · doi:10.1016/j.micpath.2019.103945 · Cited by 16 · see citing works
Methicillin-resistant Staphylococcus aureus pneumonia in diabetics
Zhang, Q.-R., Chen, H., Liu, B., & Zhou, M. (2019) · Chinese Medical Journal · doi:10.1097/cm9.0000000000000270 · Cited by 16 · see citing works
Veloso, J. D. O., Lamaro‐Cardoso, J., Neves, L. S., Borges, L. F. D. A. E., Pires, C. H., Lamaro, L., Guerreiro, T. C., Ferreira, E. M. A., & André, M. C. P. (2019) · Apmis · doi:10.1111/apm.12989 · Cited by 16 · see citing works
Kumar, V., Singh, A., Sharma, N., Saini, R., Kumar, H., El–Shazly, M., & Dev, K. (2025) · Medicine in Drug Discovery · doi:10.1016/j.medidd.2025.100228 · Cited by 19 · see citing works
Brindangnanam, P., Sawant, A. R., Prashanth, K., & Coumar, M. S. (2021) · Tissue Barriers · doi:10.1080/21688370.2021.2013695 · Cited by 15 · see citing works
The inhibition effect of Chlorpromazine against the β-lactam resistance of MRSA
Kong, R., Kang, O., Seo, Y., Mun, S., Zhou, T., Shin, D.-W., & Kwon, D. (2016) · Asian Pacific Journal of Tropical Medicine · doi:10.1016/j.apjtm.2016.04.008 · Cited by 15 · see citing works
Staphylococcus epidermidis MSCRAMM SesJ Is Encoded in Composite Islands
Arora, S., Li, X., Hillhouse, A., Konganti, K., Little, S. V., Lawhon, S. D., Threadgill, D. W., Shelburne, S. A., & Höök, M. (2020) · mBio · doi:10.1128/mbio.02911-19 · Cited by 15 · see citing works
Semmler, T., Harrison, E. M., Lübke‐Becker, A., Ulrich, R. G., Wieler, L. H., Guenther, S., Stamm, I., Hanssen, A.-M., Holmes, M. A., Vincze, S., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147150 · Cited by 14 · see citing works
Dewulf, S., Boyen, F., Paepe, D., Clercx, C., Tilman, N., Dewulf, J., & Boland, C. (2025) · Antibiotics · doi:10.3390/antibiotics14070631 · Cited by 14 · see citing works
Zhu, H., Luo, H., Zhong, Q., Cao, X., Gu, S., Peng, S., Xiao, Y., Chen, Y., Hang, Y., Fang, X., et al. (2022) · Infection and Drug Resistance · doi:10.2147/idr.s359654 · Cited by 13 · see citing works
Khalili, H., Peerayeh, S. N., Mahrooghi, M., Mansouri, P., & Bakhshi, B. (2021) · BMC Microbiology · doi:10.1186/s12866-021-02340-w · Cited by 12 · see citing works
Mayandi, V., Sridhar, S., Fazil, M. H. U. T., Goh, E. T. L., Htoon, H. M., Orive, G., Choong, Y. K., Saravanan, R., Beuerman, R. W., Barkham, T., et al. (2019) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.9b00102 · Cited by 12 · see citing works
Unveiling the Mechanisms of Bacterial Resistance and Countermeasures
Xie, Y., Lu, H., Liu, Y., Hu, G., Lian, S., Liu, J., Pang, S., Zhu, G., & Ding, X. (2025) · Pathogens · doi:10.3390/pathogens14111085 · Cited by 11 · see citing works
You, Y., Song, L., Nonyane, B. A. S., Price, L. B., & Silbergeld, E. K. (2018) · PLoS ONE · doi:10.1371/journal.pone.0193820 · Cited by 11 · see citing works
Leveraging comparative genomics to uncover alien genes in bacterial genomes
Sengupta, S., & Azad, R. K. (2023) · Microbial Genomics · doi:10.1099/mgen.0.000939 · Cited by 11 · see citing works
Ngoi, S. T., Niek, W. K., Lee, Y. W., AbuBakar, S., & Teh, C. S. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-83661-8 · Cited by 11 · see citing works
Witek, K., Kaczor, A., Żesławska, E., Podlewska, S., Marć, M. A., Czarnota-Łydka, K., Nitek, W., Latacz, G., Tejchman, W., Bischoff, M., et al. (2023) · Antibiotics · doi:10.3390/antibiotics12111618 · Cited by 10 · see citing works
Hamzah, A. M. C., Chew, C. H., Al-Trad, E. I., Puah, S. M., Chua, K. H., Rahman, N. I. A., Ismail, S. B., Maeda, T., Palittapongarnpim, P., & Yeo, C. C. (2024) · Scientific Reports · doi:10.1038/s41598-024-54182-x · Cited by 14 · see citing works
Bains, S. S., Dubin, J. A., Hameed, D., Chen, Z., Moore, M. C., Shrestha, A., Nace, J., & Delanois, R. E. (2024) · Arthroplasty · doi:10.1186/s42836-023-00222-2 · Cited by 10 · see citing works
Ho, P., Liu, M. C.-J., Tong, M.-K., Fan, P.-M., Tse, C. W., Wu, A. K. L., Cheng, V. C., & Chow, K. (2019) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2019.08.021 · Cited by 10 · see citing works
Silva, A. T. F., da Silva, J. G., Aragão, B. B., Peixoto, R. D. M., & Mota, R. A. (2020) · Tropical Animal Health and Production · doi:10.1007/s11250-020-02259-w · Cited by 10 · see citing works
Motallebi, M., Jabalameli, F., Beigverdi, R., & Emaneini, M. (2019) · Antimicrobial Resistance and Infection Control · doi:10.1186/s13756-019-0501-y · Cited by 10 · see citing works
Scharn, C. R., Tickler, I. A., Tenover, F. C., & Goering, R. V. (2022) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02374-21 · Cited by 9 · see citing works
Ersoy, S. C., Manna, A. C., Proctor, R. A., Chambers, H. F. “., Harrison, E. M., Bayer, A. S., & Cheung, A. L. (2022) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00252-22 · Cited by 9 · see citing works
Moges, F., Tamiru, T., Amare, A., Mengistu, G., Eshetie, S., Dagnew, M., Feleke, T., Gizachew, M., & Abebe, W. (2023) · International Journal of Microbiology · doi:10.1155/2023/3848073 · Cited by 12 · see citing works
Peterson, L. R., Woods, C. W., Davis, T. E., Wang, Z.-X., Young, S. A., Osiecki, J. C., Lewinski, M. A., & Liesenfeld, O. (2017) · American Journal of Clinical Pathology · doi:10.1093/ajcp/aqx040 · Cited by 9 · see citing works
Genomic islands and the evolution of livestock-associatedStaphylococcus aureusgenomes
Rao, R. T., Sharma, S., Sivakumar, N., & Jayakumar, K. (2020) · Bioscience Reports · doi:10.1042/bsr20202287 · Cited by 9 · see citing works
Djoudi, F., Bonura, C., Touati, A., Aléo, A., Benallaoua, S., & Mammina, C. (2016) · Journal of Medical Microbiology · doi:10.1099/jmm.0.000361 · Cited by 8 · see citing works
Waruwu, Y. K. K., Khairullah, A. R., Effendi, M. H., Lukiswanto, B. S., Afnani, D. A., Kurniawan, S. C., Silaen, O. S. M., Riwu, K. H. P., Widodo, A., & Ramandinianto, S. C. (2023) · Biodiversitas Journal of Biological Diversity · doi:10.13057/biodiv/d240114 · Cited by 8 · see citing works
Granato, P. A., Unz, M. M., Widen, R. H., Silbert, S., Young, S. A., Heflin, K. L., Conover, M. S., Buchan, B. W., & Ledeboer, N. A. (2018) · Journal of Clinical Microbiology · doi:10.1128/jcm.00485-18 · Cited by 8 · see citing works
Collis, R. M., Biggs, P. J., Burgess, S. A., Midwinter, A. C., Liu, J., Brightwell, G., & Cookson, A. L. (2024) · Applied and Environmental Microbiology · doi:10.1128/aem.01390-24 · Cited by 7 · see citing works
- Authors
- Hiramatsu, K., Ito, T., Tsubakishita, S., Sasaki, T., Takeuchi, F., Morimoto, Y., Katayama, Y., Matsuo, M., Kuwahara-Arai, K., Hishinuma, T., & Baba, T.
- Affiliations
- Juntendo University (JP)
- Rakuno Gakuen University (JP)
- National Institute of Infectious Diseases (JP)
- Department of Bacteriology, Juntendo University, Tokyo, Japan.
- Corresponding author
- Hiramatsu, Keiichi
- ORCID
- Venue
- Infection & Chemotherapy
- Publisher
- XMLink
- Published
- 2013
- Volume
- 45
- Issue
- 2
- Pages
- 117
- ISSN
- 1598-8112 (ISSN-L)
- 2093-2340
- 2092-6448
- PMC
- PMC3780952
- OpenAlex
- W1969730343
- Cited by
- 189
- References
- 114
- Citations by year
- 2026: 6 · 2025: 14 · 2024: 14 · 2023: 17 · 2022: 16 · 2021: 17 · 2020: 20 · 2019: 25 · 2018: 16 · 2017: 9 · 2016: 15 · 2015: 12 · 2014: 8
- FWCI
- 1.48
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Infection and Chemotherapy (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Institutional Repositories DataBase (IRDB) (publishedVersion, other-oa)
- Funders
- Ministry of Education, Culture, Sports, Science and Technology (S1201013)
- Japan Society for the Promotion of Science (24780298)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Antibiotic Resistance in Bacteria
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Keywords
- methicillin resistance, Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, multidrug resistance, antimicrobial resistance, MRSA clones, community-acquired MRSA, hospital-acquired MRSA, bacterial genomics, pathogenicity, immunocompromised patients
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review